Published in J Am Chem Soc on March 17, 2007
Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils. PLoS Comput Biol (2007) 1.71
Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour. Nat Commun (2014) 1.20
Inhibition of amyloid peptide fibrillation by inorganic nanoparticles: functional similarities with proteins. Angew Chem Int Ed Engl (2011) 1.06
Human serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanism. Biophys J (2009) 1.05
Phenolic compounds prevent amyloid β-protein oligomerization and synaptic dysfunction by site-specific binding. J Biol Chem (2012) 1.05
Stoichiometry and affinity of the human serum albumin-Alzheimer's Aβ peptide interactions. Biophys J (2011) 0.99
Conformational recognition of an intrinsically disordered protein. Biophys J (2014) 0.98
Human serum albumin can regulate amyloid-β peptide fiber growth in the brain interstitium: implications for Alzheimer disease. J Biol Chem (2012) 0.97
Unfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis. EMBO J (2014) 0.96
Soluble aggregates of the amyloid-beta peptide are trapped by serum albumin to enhance amyloid-beta activation of endothelial cells. J Biol Eng (2009) 0.91
Serum albumin concentration and cognitive impairment. Curr Alzheimer Res (2010) 0.90
A new function of human HtrA2 as an amyloid-beta oligomerization inhibitor. J Alzheimers Dis (2009) 0.88
Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies. J Biol Chem (2008) 0.84
Aβ association inhibition by transferrin. Biophys J (2013) 0.84
Structural characterization and inhibition of toxic amyloid-β oligomeric intermediates. Biophys J (2013) 0.83
Mapping the interactions between the Alzheimer's Aβ-peptide and human serum albumin beyond domain resolution. Biophys J (2013) 0.82
Development and validation of risk index for cognitive decline using blood-derived markers. Neurology (2015) 0.81
Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner. Sci Rep (2015) 0.79
Fluorescent filter-trap assay for amyloid fibril formation kinetics in complex solutions. ACS Chem Neurosci (2015) 0.78
Structural basis of synaptic vesicle assembly promoted by α-synuclein. Nat Commun (2016) 0.76
Structural and fluctuational difference between two ends of Aβ amyloid fibril: MD simulations predict only one end has open conformations. Sci Rep (2016) 0.75
Amyloid-β adopts a conserved, partially folded structure upon binding to zwitterionic lipid bilayers prior to amyloid formation. Chem Commun (Camb) (2016) 0.75
Probing conformational dynamics in biomolecules via chemical exchange saturation transfer: a primer. J Biomol NMR (2017) 0.75
Temperature dependence of Congo red binding to amyloid β12-28. Eur Biophys J (2013) 0.75
Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell (2009) 4.78
Conformational coupling across the plasma membrane in activation of the EGF receptor. Cell (2013) 2.49
Architecture and membrane interactions of the EGF receptor. Cell (2013) 2.29
Mapping allostery through the covariance analysis of NMR chemical shifts. Proc Natl Acad Sci U S A (2011) 1.89
cAMP activation of PKA defines an ancient signaling mechanism. Proc Natl Acad Sci U S A (2006) 1.79
MicroRNA-199b-5p impairs cancer stem cells through negative regulation of HES1 in medulloblastoma. PLoS One (2009) 1.73
The alpha-to-beta conformational transition of Alzheimer's Abeta-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of beta conformation seeding. Chembiochem (2006) 1.70
Dynamically driven ligand selectivity in cyclic nucleotide binding domains. J Biol Chem (2009) 1.38
Signaling through dynamic linkers as revealed by PKA. Proc Natl Acad Sci U S A (2013) 1.28
Regulation of the catalytic activity of the EGF receptor. Curr Opin Struct Biol (2011) 1.26
Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife (2013) 1.22
Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP. J Biol Chem (2008) 1.21
Josephin domain of ataxin-3 contains two distinct ubiquitin-binding sites. Biopolymers (2009) 1.17
A model for agonism and antagonism in an ancient and ubiquitous cAMP-binding domain. J Biol Chem (2006) 1.16
Interaction of sweet proteins with their receptor. A conformational study of peptides corresponding to loops of brazzein, monellin and thaumatin. Eur J Biochem (2004) 1.11
Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIalpha. Proteins (2007) 1.10
Mapping allostery through equilibrium perturbation NMR spectroscopy. J Am Chem Soc (2006) 1.10
The projection analysis of NMR chemical shifts reveals extended EPAC autoinhibition determinants. Biophys J (2012) 1.10
Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting. Nat Chem Biol (2009) 1.09
Communication between tandem cAMP binding domains in the regulatory subunit of protein kinase A-Ialpha as revealed by domain-silencing mutations. J Biol Chem (2010) 1.05
Human serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanism. Biophys J (2009) 1.05
The auto-inhibitory role of the EPAC hinge helix as mapped by NMR. PLoS One (2012) 1.05
A new modified thrombin binding aptamer containing a 5'-5' inversion of polarity site. Nucleic Acids Res (2006) 1.04
Stoichiometry and affinity of the human serum albumin-Alzheimer's Aβ peptide interactions. Biophys J (2011) 0.99
Induction of flexibility through protein-protein interactions. J Biol Chem (2003) 0.99
Cold denaturation of yeast frataxin offers the clue to understand the effect of alcohols on protein stability. J Am Chem Soc (2008) 0.98
Understanding cAMP-dependent allostery by NMR spectroscopy: comparative analysis of the EPAC1 cAMP-binding domain in its apo and cAMP-bound states. J Am Chem Soc (2007) 0.98
Stability and structure of telomeric DNA sequences forming quadruplexes containing four G-tetrads with different topological arrangements. Biochemistry (2004) 0.98
NMR solution structure of a parallel LNA quadruplex. Nucleic Acids Res (2004) 0.93
Role of dynamics in the autoinhibition and activation of the exchange protein directly activated by cyclic AMP (EPAC). J Biol Chem (2011) 0.93
Understanding cold denaturation: the case study of Yfh1. J Am Chem Soc (2010) 0.92
An apolipoprotein AI mimetic peptide: membrane interactions and the role of cholesterol. Biochemistry (2004) 0.92
Thermodynamics and kinetics of PNA-DNA quadruplex-forming chimeras. J Am Chem Soc (2005) 0.89
8-methyl-2'-deoxyguanosine incorporation into parallel DNA quadruplex structures. Nucleic Acids Res (2005) 0.88
Mapping polypeptide self-recognition through (1)H off-resonance relaxation. J Am Chem Soc (2005) 0.88
A new function of human HtrA2 as an amyloid-beta oligomerization inhibitor. J Alzheimers Dis (2009) 0.88
Position of residues in transmembrane peptides with respect to the lipid bilayer: a combined lipid Noes and water chemical exchange approach in phospholipid bicelles. J Biomol NMR (2002) 0.87
Structural studies on LNA quadruplexes. Nucleosides Nucleotides Nucleic Acids (2005) 0.87
NMR structures reveal how oxidation inactivates thrombomodulin. Biochemistry (2003) 0.87
Biophysical properties of quadruple helices of modified human telomeric DNA. Biopolymers (2005) 0.86
Effects of 8-methyl-2'-deoxyadenosine incorporation into quadruplex forming oligodeoxyribonucleotides. Bioorg Med Chem (2005) 0.86
Analysis and optimization of saturation transfer difference NMR experiments designed to map early self-association events in amyloidogenic peptides. J Phys Chem B (2008) 0.86
Effect of chemical exchange on radiation damping in aqueous solutions of the osmolyte glycine. J Am Chem Soc (2002) 0.86
cAMP-dependent allostery and dynamics in Epac: an NMR view. Biochem Soc Trans (2012) 0.85
Using chemical exchange to assign non-covalent protein complexes in slow exchange with the free state: enhanced resolution and efficient signal editing. J Biomol NMR (2004) 0.85
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes. Biochimie (2010) 0.85
Tapping the translation potential of cAMP signalling: molecular basis for selectivity in cAMP agonism and antagonism as revealed by NMR. Biochem Soc Trans (2014) 0.84
Aβ association inhibition by transferrin. Biophys J (2013) 0.84
Relative stability of quadruplexes containing different number of G-tetrads. Nucleosides Nucleotides Nucleic Acids (2005) 0.84
NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit. J Biomol NMR (2006) 0.84
Mapping the interactions between the Alzheimer's Aβ-peptide and human serum albumin beyond domain resolution. Biophys J (2013) 0.82
In vitro amyloid-β binding and inhibition of amyloid-β self-association by therapeutic albumin. J Alzheimers Dis (2014) 0.82
High-resolution protein hydration NMR experiments: probing how protein surfaces interact with water and other non-covalent ligands. Anal Chim Acta (2005) 0.82
The kinase domain of Drosophila Tribbles is required for turnover of fly C/EBP during cell migration. Dev Biol (2013) 0.81
Interaction of distamycin A and netropsin with quadruplex and duplex structures: a comparative 1H-NMR study. Nucleosides Nucleotides Nucleic Acids (2002) 0.81
Allosteric linkers in cAMP signalling. Biochem Soc Trans (2014) 0.81
Analysis and parametric optimization of 1H off-resonance relaxation NMR experiments designed to map polypeptide self-recognition and other noncovalent interactions. J Phys Chem B (2006) 0.81
The abasic site lesions in the human telomeric sequence d[TA(G(3)T(2)A)(3)G(3)]: a thermodynamic point of view. Biochim Biophys Acta (2012) 0.80
Dynamics of the fragment of thrombomodulin containing the fourth and fifth epidermal growth factor-like domains correlate with function. Biochemistry (2005) 0.80
Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands. Bioorg Med Chem (2011) 0.80
Strand directionality affects cation binding and movement within tetramolecular G-quadruplexes. Nucleic Acids Res (2012) 0.79
Structural investigations on the anti-HIV G-quadruplex-forming oligonucleotide TGGGAG and its analogues: evidence for the presence of an A-tetrad. Chembiochem (2012) 0.79
Dynamic unfolding of a regulatory subunit of cAMP-dependent protein kinase by capillary electrophoresis: Impact of cAMP dissociation on protein stability. Electrophoresis (2006) 0.78
5-Hydroxymethyl-2'-deoxyuridine residues in the thrombin binding aptamer: investigating anticoagulant activity by making a tiny chemical modification. Chembiochem (2014) 0.78
The insertion of two 8-methyl-2'-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands. Nucleic Acids Res (2011) 0.78
Unprecedented right- and left-handed quadruplex structures formed by heterochiral oligodeoxyribonucleotides. Biochimie (2011) 0.77
Molecular modelling studies of four stranded quadruplexes containing a 3'-3' or 5'-5' inversion of polarity site. Nucleosides Nucleotides Nucleic Acids (2007) 0.77
The oxidative damage to the human telomere: effects of 5-hydroxymethyl-2'-deoxyuridine on telomeric G-quadruplex structures. Org Biomol Chem (2015) 0.77
Expanding the potential of G-quadruplex structures: formation of a heterochiral TBA analogue. Chembiochem (2014) 0.77
Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer. Eur J Med Chem (2012) 0.77
Cystatins: a versatile family. Biomol Concepts (2011) 0.77
A novel non-canonical forkhead-associated (FHA) domain-binding interface mediates the interaction between Rad53 and Dbf4 proteins. J Biol Chem (2013) 0.77
Ultrasonic and densimetric characterization of the association of cyclic AMP with the cAMP-binding domain of the exchange protein EPAC1. J Phys Chem B (2013) 0.77
Interaction of porphyrin with G-quadruplex structures. Nucleosides Nucleotides Nucleic Acids (2005) 0.77
Label-free assay for thermodynamic analysis of protein-ligand interactions: a multivariate strategy for allosteric ligand screening. Biochemistry (2009) 0.76
Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA. Bioorg Med Chem Lett (2013) 0.76
Structural Basis of Tonic Inhibition by Dimers of Dimers in Hyperpolarization-Activated Cyclic-Nucleotide-Modulated (HCN) Ion Channels. J Phys Chem B (2016) 0.76
Synthesis and structural study of quadruplex structures containing 2'-deoxy-8-methyladenosine. Nucleosides Nucleotides Nucleic Acids (2005) 0.75
A novel equilibrium relating to the helix handedness in G-quadruplexes formed by heterochiral oligonucleotides with an inversion of polarity site. Chem Commun (Camb) (2013) 0.75
The Introduction of Inversion of Polarity Sites in DNA G-Quadruplex Structures: Effects and Perspectives. Mini Rev Med Chem (2016) 0.75
Configuration assignment in small organic molecules via residual dipolar couplings. Chem Commun (Camb) (2003) 0.75
1H-NMR study of the quadruplex [d(TGGGT)]4 containing a modified thymine. Nucleosides Nucleotides Nucleic Acids (2003) 0.75
More than one non-canonical phosphodiester bond in the G-tract: formation of unusual parallel G-quadruplex structures. Org Biomol Chem (2013) 0.75