Published in J Gene Med on November 01, 2005
Ultrasound with microbubbles enhances gene expression of plasmid DNA in the liver via intraportal delivery. Gene Ther (2008) 1.24
Key factors that affect sonoporation efficiency in in vitro settings: the importance of standing wave in sonoporation. Biochem Biophys Res Commun (2007) 1.18
Advances in Gene Delivery Systems. Pharmaceut Med (2011) 1.09
Plasmid releasing multiple channel bridges for transgene expression after spinal cord injury. Mol Ther (2008) 1.03
Physical approaches for nucleic acid delivery to liver. AAPS J (2008) 0.92
Calibration of the 1-MHz Sonitron ultrasound system. Ultrasound Med Biol (2010) 0.85
Enhancement of adenovirus delivery after ultrasound-stimulated therapy in a cancer model. Ultrasound Med Biol (2013) 0.81
Gene delivery strategies to promote spinal cord repair. Biomark Insights (2015) 0.79
Non-viral gene therapy for spinal cord regeneration. Drug Discov Today (2012) 0.77
Photomechanical wave-driven delivery of siRNAs targeting intermediate filament proteins promotes functional recovery after spinal cord injury in rats. PLoS One (2012) 0.76
Nerve growth factor delivery by ultrasound-mediated nanobubble destruction as a treatment for acute spinal cord injury in rats. Int J Nanomedicine (2017) 0.75
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med (2005) 6.86
The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014). Hypertens Res (2014) 4.83
Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians. Nat Genet (2011) 4.04
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol (2004) 3.85
Periostin: a novel component of subepithelial fibrosis of bronchial asthma downstream of IL-4 and IL-13 signals. J Allergy Clin Immunol (2006) 3.24
The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci (2003) 3.20
Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia. Circulation (2008) 2.82
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature (2009) 2.74
Diagnostic accuracy of 11C-methionine PET for differentiation of recurrent brain tumors from radiation necrosis after radiotherapy. J Nucl Med (2008) 2.65
Hypoadiponectinemia is an independent risk factor for hypertension. Hypertension (2004) 2.65
CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation. J Biol Chem (2008) 2.63
Association of hypoadiponectinemia with impaired vasoreactivity. Hypertension (2003) 2.32
Serum uric acid and plasma norepinephrine concentrations predict subsequent weight gain and blood pressure elevation. Hypertension (2003) 2.26
Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3. Nat Immunol (2005) 2.24
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol (2003) 2.24
Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells. Arterioscler Thromb Vasc Biol (2005) 2.20
Predicting successful guidewire crossing through chronic total occlusion of native coronary lesions within 30 minutes: the J-CTO (Multicenter CTO Registry in Japan) score as a difficulty grading and time assessment tool. JACC Cardiovasc Interv (2011) 2.12
The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho. J Cell Biol (2002) 2.08
Pulmonary venous flow and risk of cardiovascular disease in essential hypertension. J Hypertens (2008) 2.05
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Abeta deposition in an Alzheimer mouse model with diabetes. Proc Natl Acad Sci U S A (2010) 1.97
Local delivery of plasmid DNA into rat carotid artery using ultrasound. Circulation (2002) 1.94
Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway. Stem Cells (2007) 1.92
Comparison of infliximab versus ciclosporin during the initial 6-month treatment period in Behçet disease. Br J Ophthalmol (2009) 1.91
Inhibitory effects of novel AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell proliferation in vitro and neointimal formation in vivo. Circ Res (2002) 1.87
Periostin as a novel factor responsible for ventricular dilation. Circulation (2004) 1.85
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. EMBO J (2004) 1.82
Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy. J Atheroscler Thromb (2006) 1.78
Homocysteine enhances endothelial apoptosis via upregulation of Fas-mediated pathways. Hypertension (2004) 1.76
Prevention of cardiovascular events with calcium channel blocker-based combination therapies in patients with hypertension: a randomized controlled trial. J Hypertens (2011) 1.75
Telmisartan but not valsartan increases caloric expenditure and protects against weight gain and hepatic steatosis. Hypertension (2006) 1.74
Identification of hypertension-susceptibility genes and pathways by a systemic multiple candidate gene approach: the millennium genome project for hypertension. Hypertens Res (2008) 1.72
Effectiveness of paclitaxel-eluting balloon catheter in patients with sirolimus-eluting stent restenosis. JACC Cardiovasc Interv (2011) 1.70
Anti-apoptotic and anti-senescence effects of Klotho on vascular endothelial cells. Biochem Biophys Res Commun (2005) 1.68
Ultrasound-microbubble-mediated intercellular adhesion molecule-1 small interfering ribonucleic acid transfection attenuates neointimal formation after arterial injury in mice. J Am Coll Cardiol (2010) 1.68
Blood pressure and hypertension are associated with 7 loci in the Japanese population. Circulation (2010) 1.66
Leptin-receptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic nerve activation in a Caucasian male population. Hypertens Res (2008) 1.66
Synthetic pores with reactive signal amplifiers as artificial tongues. Nat Mater (2007) 1.63
Two different coronary blood flow velocity patterns in thrombolysis in myocardial infarction flow grade 2 in acute myocardial infarction: insight into mechanisms of microvascular dysfunction. J Am Coll Cardiol (2002) 1.63
A haplotype of the CYP4A11 gene associated with essential hypertension in Japanese men. J Hypertens (2008) 1.62
Deletion of angiotensin-converting enzyme 2 accelerates pressure overload-induced cardiac dysfunction by increasing local angiotensin II. Hypertension (2006) 1.61
Multiple hepatic peribiliary cysts with cirrhosis. J Gastroenterol (2004) 1.57
Hepatocyte growth factor reduces cardiac fibrosis by inhibiting endothelial-mesenchymal transition. Hypertension (2012) 1.56
alpha-Adducin Gly460Trp polymorphism is associated with low renin hypertension in younger subjects in the Ohasama study. J Hypertens (2002) 1.55
Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction. Hypertension (2006) 1.54
Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity. J Cell Biol (2002) 1.54
Essential role for miR-196a in brown adipogenesis of white fat progenitor cells. PLoS Biol (2012) 1.53
Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model. J Mol Cell Cardiol (2006) 1.52
Reevaluation of the association of seven candidate genes with blood pressure and hypertension: a replication study and meta-analysis with a larger sample size. Hypertens Res (2012) 1.51
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia. FEBS Lett (2002) 1.51
Serum interleukin-15 concentration in patients with essential hypertension. Am J Hypertens (2005) 1.49
Seven-year clinical outcomes of unprotected left main coronary artery stenting with drug-eluting stent and bare-metal stent. Circ J (2013) 1.48
Angiotensin-converting enzyme I/D polymorphism and hypertension: the Ohasama study. J Hypertens (2002) 1.48
Role of diabetes and obesity in outcomes of the candesartan antihypertensive survival evaluation in Japan (CASE-J) trial. Hypertens Res (2010) 1.47
Analysis of venous drainage from sylvian veins in clinoidal meningiomas. World Neurosurg (2011) 1.47
Tissue inhibitor of metalloproteinase-3 deficiency inhibits blood pressure elevation and myocardial microvascular remodeling induced by chronic administration of Nomega-nitro-L-arginine methyl ester in mice. Hypertens Res (2007) 1.47
Accumulation of common polymorphisms is associated with development of hypertension: a 12-year follow-up from the Ohasama study. Hypertens Res (2009) 1.47
Ectopic expression of homeodomain protein CDX2 in intestinal metaplasia and carcinomas of the stomach. Cancer Lett (2002) 1.45
High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet (2007) 1.44
Association of blood pressure control and metabolic syndrome with cardiovascular risk in elderly Japanese: JATOS study. Am J Hypertens (2011) 1.44
Rebound weight gain as associated with high plasma norepinephrine levels that are mediated through polymorphisms in the beta2-adrenoceptor. Am J Hypertens (2005) 1.44
Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12. Neurosci Lett (2004) 1.43
Influence of adrenomedullin 2/intermedin gene polymorphism on blood pressure, renal function and silent cerebrovascular lesions in Japanese: the Ohasama study. Hypertens Res (2011) 1.43
Linker histone variants control chromatin dynamics during early embryogenesis. Proc Natl Acad Sci U S A (2005) 1.43
Haplotype-based case-control study of the human CYP4F2 gene and essential hypertension in Japanese subjects. Hypertens Res (2008) 1.43
Epsilon 4 allele of apolipoprotein E gene associates with lower blood pressure in young Japanese subjects: the Suita Study. J Hypertens (2002) 1.42
Induction of neuronal death by ER stress in Alzheimer's disease. J Chem Neuroanat (2004) 1.42
Angiotensin II accelerates osteoporosis by activating osteoclasts. FASEB J (2008) 1.42
Deletion allele of the angiotensin-converting enzyme gene as a risk factor for pneumonia in elderly patients. Am J Med (2002) 1.41
Effects of cardiac complications on cardiovascular events in Japanese high-risk hypertensive patients: subanalysis of the CASE-J trial. Circ J (2009) 1.40
Effects of weight loss on renal function in overweight Japanese men. Hypertens Res (2011) 1.39
NF-kappaB is a key mediator of cerebral aneurysm formation. Circulation (2007) 1.39
Comparison of strict- and mild-blood pressure control in elderly hypertensive patients: a per-protocol analysis of JATOS. Hypertens Res (2010) 1.39
PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia. Proc Natl Acad Sci U S A (2011) 1.38
Optimal treatment of recurrent restenosis lesions after drug-eluting stent implantation for in-stent restenosis lesions. EuroIntervention (2013) 1.38
Snail, a transcriptional regulator, represses nephrin expression in glomerular epithelial cells of nephrotic rats. Lab Invest (2007) 1.38
Confirmation of ALDH2 as a Major locus of drinking behavior and of its variants regulating multiple metabolic phenotypes in a Japanese population. Circ J (2011) 1.37