Published in J Chem Neuroanat on September 01, 2004
Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis. Endocr Rev (2008) 2.79
A review of the mammalian unfolded protein response. Biotechnol Bioeng (2011) 1.83
ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology. J Neuroinflammation (2009) 1.46
Role of Bim in regulating CD8+ T-cell responses during chronic viral infection. J Virol (2006) 1.32
Localization of GRP78 to mitochondria under the unfolded protein response. Biochem J (2006) 1.29
Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides. Biochem J (2007) 1.24
PERK-dependent regulation of IAP translation during ER stress. Oncogene (2008) 1.23
Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders. Expert Opin Ther Targets (2011) 1.22
Overexpressed cyclophilin B suppresses apoptosis associated with ROS and Ca2+ homeostasis after ER stress. J Cell Sci (2008) 1.17
A novel pathogenic role of the ER chaperone GRP78/BiP in rheumatoid arthritis. J Exp Med (2012) 1.14
Mechanisms of alcohol-induced endoplasmic reticulum stress and organ injuries. Biochem Res Int (2011) 1.14
AlzPathway: a comprehensive map of signaling pathways of Alzheimer's disease. BMC Syst Biol (2012) 1.13
Ethanol promotes endoplasmic reticulum stress-induced neuronal death: involvement of oxidative stress. J Neurosci Res (2008) 1.06
Cloning, expression, and functional characterization of relaxin receptor (leucine-rich repeat-containing g protein-coupled receptor 7) splice variants from human fetal membranes. Endocrinology (2007) 1.04
Sigma-1 receptor chaperone at the ER-mitochondrion interface mediates the mitochondrion-ER-nucleus signaling for cellular survival. PLoS One (2013) 1.02
Melatonin in Alzheimer's disease and other neurodegenerative disorders. Behav Brain Funct (2006) 1.01
Thiamine deficiency induces endoplasmic reticulum stress in neurons. Neuroscience (2006) 1.01
Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers. Int J Cell Biol (2012) 0.96
Oxidative stress by targeted agents promotes cytotoxicity in hematologic malignancies. Antioxid Redox Signal (2009) 0.95
Central nervous system endoplasmic reticulum stress in a murine model of type 2 diabetes. Diabetologia (2012) 0.95
Heat shock proteins in neurodegenerative disorders and aging. J Cell Commun Signal (2014) 0.93
Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegeneration. Cellscience (2007) 0.92
Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol (2008) 0.92
Herpes Simplex Virus Type 1 and Other Pathogens are Key Causative Factors in Sporadic Alzheimer's Disease. J Alzheimers Dis (2015) 0.91
The unfolded protein response in Alzheimer's disease. Semin Immunopathol (2013) 0.90
Neuronal cell death in Alzheimer's disease and a neuroprotective factor, humanin. Curr Neuropharmacol (2006) 0.88
Interplay of endoplasmic reticulum stress and autophagy in neurodegenerative disorders. Autophagy (2016) 0.88
Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory. Neuropathol Appl Neurobiol (2015) 0.88
Hypothalamic microinflammation: a common basis of metabolic syndrome and aging. Trends Neurosci (2014) 0.88
Activating transcription factor 4, a mediator of the integrated stress response, is increased in the dorsal root ganglia following painful facet joint distraction. Neuroscience (2011) 0.85
Sphingolipid metabolic pathway: an overview of major roles played in human diseases. J Lipids (2013) 0.85
Valosin-containing protein gene mutations: cellular phenotypes relevant to neurodegeneration. J Mol Neurosci (2011) 0.83
Tunicamycin-induced unfolded protein response in the developing mouse brain. Toxicol Appl Pharmacol (2015) 0.82
Endoplasmic reticulum stress-unfolding protein response-apoptosis cascade causes chondrodysplasia in a col2a1 p.Gly1170Ser mutated mouse model. PLoS One (2014) 0.82
TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS. Dis Model Mech (2013) 0.82
Trends in the molecular pathogenesis and clinical therapeutics of common neurodegenerative disorders. Int J Mol Sci (2009) 0.82
Iron depletion increases manganese uptake and potentiates apoptosis through ER stress. Neurotoxicology (2013) 0.82
Endoplasmic reticulum stress promotes amyloid-beta peptides production in RGC-5 cells. Cell Stress Chaperones (2014) 0.81
Novel concepts on pregnancy clocks and alarms: redundancy and synergy in human parturition. Hum Reprod Update (2016) 0.81
Uterine endoplasmic reticulum stress and its unfolded protein response may regulate caspase 3 activation in the pregnant mouse uterus. PLoS One (2013) 0.80
Characterization of the endocannabinoid system in human neuronal cells and proteomic analysis of anandamide-induced apoptosis. J Biol Chem (2009) 0.79
Gene expression in primary cultured astrocytes affected by aluminum: alteration of chaperons involved in protein folding. Environ Health Prev Med (2010) 0.79
Human telomerase reverse transcriptase and glucose-regulated protein 78 increase the life span of articular chondrocytes and their repair potential. BMC Musculoskelet Disord (2012) 0.79
Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers. Nat Rev Neurol (2016) 0.79
Endoplasmic reticulum stress response as a potential therapeutic target in multiple sclerosis. Therapy (2008) 0.79
Linking cocaine to endoplasmic reticulum in striatal neurons: role of glutamate receptors. Basal Ganglia (2011) 0.79
HMGA1a trapping of U1 snRNP at an authentic 5' splice site induces aberrant exon skipping in sporadic Alzheimer's disease. Mol Cell Biol (2010) 0.78
γ-Secretase complexes containing caspase-cleaved presenilin-1 increase intracellular Aβ(42) /Aβ(40) ratio. J Cell Mol Med (2011) 0.78
Endoplasmic reticulum stress impairment in the spinal dorsal horn of a neuropathic pain model. Sci Rep (2015) 0.78
Humic Acid Increases Amyloid β-Induced Cytotoxicity by Induction of ER Stress in Human SK-N-MC Neuronal Cells. Int J Mol Sci (2015) 0.78
The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained. Cell Calcium (2016) 0.78
Endoplasmic reticulum stress upregulates the chondroitin sulfate level which thus prevents neurite extension in C6 glioma cells and primary cultured astrocytes. Cell Mol Neurobiol (2008) 0.77
Involvement of calcium-mediated reactive oxygen species in inductive GRP78 expression by geldanamycin in 9L rat brain tumor cells. Int J Mol Sci (2013) 0.76
Transgenic mouse and cell culture models demonstrate a lack of mechanistic connection between endoplasmic reticulum stress and tau dysfunction. J Neurosci Res (2010) 0.76
The High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development. Curr Mol Med (2016) 0.75
FAD-linked Presenilin-1 V97L mutation impede tranport regulation and intracellular Ca(2+) homeostasis under ER stress. Int J Clin Exp Med (2015) 0.75
The Unfolded Protein Response Regulates Uterine Myocyte Antioxidant Responsiveness During Pregnancy. Biol Reprod (2016) 0.75
Regulation of intracellular calcium in cortical neurons transgenic for human Abeta40 and Abeta42 following nutritive challenge. Int J Clin Exp Med (2009) 0.75
Sequestration of sorcin by aberrant forms of tau results in the defective calcium homeostasis. Korean J Physiol Pharmacol (2016) 0.75
Epithelial sodium channel abundance is decreased by an unfolded protein response induced by hyperosmolality. Physiol Rep (2014) 0.75
Long-term dantrolene treatment reduced intraneuronal amyloid in aged Alzheimer triple transgenic mice. Alzheimer Dis Assoc Disord (2015) 0.75
Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat Chem Biol (2008) 9.24
Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol (2006) 8.89
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol (2004) 3.85
The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci (2003) 3.20
MafA is a key regulator of glucose-stimulated insulin secretion. Mol Cell Biol (2005) 2.85
Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes. J Biol Chem (2003) 2.66
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation. Nat Cell Biol (2009) 2.38
OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes. Nat Cell Biol (2005) 2.29
The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho. J Cell Biol (2002) 2.08
The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology. J Biochem (2011) 1.99
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi. EMBO J (2004) 1.82
Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system. Nat Neurosci (2012) 1.77
Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2. J Biol Chem (2010) 1.72
Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol (2009) 1.69
Functional images reflect aggressiveness of endometrial carcinoma: estrogen receptor expression combined with 18F-FDG PET. J Nucl Med (2009) 1.57
Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1. EMBO J (2002) 1.57
Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress. J Neurochem (2006) 1.56
Cytoplasmic p21(Cip1/WAF1) regulates neurite remodeling by inhibiting Rho-kinase activity. J Cell Biol (2002) 1.54
Feasibility of 62Cu-ATSM PET for evaluation of brain ischaemia and misery perfusion in patients with cerebrovascular disease. Eur J Nucl Med Mol Imaging (2011) 1.53
BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer. Mol Cell Biol (2006) 1.52
c-Maf plays a crucial role for the definitive erythropoiesis that accompanies erythroblastic island formation in the fetal liver. Blood (2011) 1.51
Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia. FEBS Lett (2002) 1.51
The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease. Hum Mol Genet (2006) 1.50
A focused microarray approach to functional glycomics: transcriptional regulation of the glycome. Glycobiology (2005) 1.49
MafB is essential for renal development and F4/80 expression in macrophages. Mol Cell Biol (2006) 1.48
Peripheral ethanolamine plasmalogen deficiency: a logical causative factor in Alzheimer's disease and dementia. J Lipid Res (2007) 1.48
Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12. Neurosci Lett (2004) 1.43
Molecular mechanisms responsible for aberrant splicing of SERCA1 in myotonic dystrophy type 1. Hum Mol Genet (2007) 1.43
Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue. Sci Rep (2012) 1.42
Radioactive iodine (131I) therapy for differentiated thyroid cancer in Japan: current issues with historical review and future perspective. Ann Nucl Med (2011) 1.39
Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. Nat Genet (2012) 1.38
Age-related decline in circadian output. J Neurosci (2011) 1.38
Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease. J Cell Biol (2002) 1.33
Identification of a cis-acting element for the regulation of SMN exon 7 splicing. J Biol Chem (2002) 1.33
MDG1/ERdj4, an ER-resident DnaJ family member, suppresses cell death induced by ER stress. Genes Cells (2003) 1.29
Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1. Mol Cell Biol (2007) 1.28
The dorsomedial hypothalamic nucleus is not necessary for food-anticipatory circadian rhythms of behavior, temperature or clock gene expression in mice. Eur J Neurosci (2009) 1.28
An intronic splicing enhancer element in survival motor neuron (SMN) pre-mRNA. J Biol Chem (2003) 1.28
Expression of the circadian clock gene Period2 in the hippocampus: possible implications for synaptic plasticity and learned behaviour. ASN Neuro (2009) 1.26
A novel FERM domain including guanine nucleotide exchange factor is involved in Rac signaling and regulates neurite remodeling. J Neurosci (2002) 1.24
Is misery perfusion still a predictor of stroke in symptomatic major cerebral artery disease? Brain (2012) 1.23
bFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healing. PLoS One (2010) 1.23
JAB1 participates in unfolded protein responses by association and dissociation with IRE1. Neurochem Int (2004) 1.21
The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system. EMBO Mol Med (2009) 1.20
Role of Herp in the endoplasmic reticulum stress response. Genes Cells (2004) 1.19
In vivo monitoring of peripheral circadian clocks in the mouse. Curr Biol (2012) 1.19
CARM1 regulates proliferation of PC12 cells by methylating HuD. Mol Cell Biol (2006) 1.19
Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells. Proc Natl Acad Sci U S A (2005) 1.19
An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease. EMBO J (2004) 1.18
Assessment of internal exposure doses in Fukushima by a whole body counter within one month after the nuclear power plant accident. Radiat Res (2013) 1.17
PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts. EMBO J (2003) 1.17
Peg3/Pw1 is involved in p53-mediated cell death pathway in brain ischemia/hypoxia. J Biol Chem (2001) 1.16
Mouse Prickle1 and Prickle2 are expressed in postmitotic neurons and promote neurite outgrowth. FEBS Lett (2007) 1.15
Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T10. FEBS Lett (2002) 1.12
Environmental contamination and external radiation dose rates from radionuclides released from the Fukushima Nuclear Power Plant. Radiat Prot Dosimetry (2012) 1.12
Pericentrin, a centrosomal protein related to microcephalic primordial dwarfism, is required for olfactory cilia assembly in mice. FASEB J (2009) 1.11
The impact of a genome-wide supported psychosis variant in the ZNF804A gene on memory function in schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2010) 1.11
Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum (ER) stress-induced retinal cell death. Invest Ophthalmol Vis Sci (2008) 1.11
Cytosolic acetyl-CoA synthetase affected tumor cell survival under hypoxia: the possible function in tumor acetyl-CoA/acetate metabolism. Cancer Sci (2009) 1.11
Tra2 beta, SF2/ASF and SRp30c modulate the function of an exonic splicing enhancer in exon 10 of tau pre-mRNA. Genes Cells (2004) 1.11
XBP1 activates the transcription of its target genes via an ACGT core sequence under ER stress. Biochem Biophys Res Commun (2005) 1.10
Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. J Biol Chem (2002) 1.10
Analysis of genes induced in peripheral nerve after axotomy using cDNA microarrays. J Neurochem (2002) 1.10
Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2. J Biol Chem (2002) 1.09
DISC1 localizes to the centrosome by binding to kendrin. Biochem Biophys Res Commun (2004) 1.08
Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia. Biochem Biophys Res Commun (2008) 1.08
Promotion of axon regeneration by myelin-associated glycoprotein and Nogo through divergent signals downstream of Gi/G. J Neurosci (2004) 1.08
SORL1 is genetically associated with Alzheimer disease in a Japanese population. Neurosci Lett (2009) 1.07
EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway. J Biol Chem (2004) 1.07
Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson's disease and Huntington's disease. Neurochem Int (2005) 1.06
Tumor uptake of radiolabeled acetate reflects the expression of cytosolic acetyl-CoA synthetase: implications for the mechanism of acetate PET. Nucl Med Biol (2009) 1.06
Activation of Rho in the injured axons following spinal cord injury. EMBO Rep (2004) 1.06
Physiological unfolded protein response regulated by OASIS family members, transmembrane bZIP transcription factors. IUBMB Life (2011) 1.05
The unfolded protein response is involved in the pathology of Alzheimer's disease. Ann N Y Acad Sci (2002) 1.04
A novel I-branching beta-1,6-N-acetylglucosaminyltransferase involved in human blood group I antigen expression. Blood (2002) 1.04
Differential roles of two N-acetylgalactosaminyltransferases, CSGalNAcT-1, and a novel enzyme, CSGalNAcT-2. Initiation and elongation in synthesis of chondroitin sulfate. J Biol Chem (2002) 1.04
Genetic fate mapping of Olig2 progenitors in the injured adult cerebral cortex reveals preferential differentiation into astrocytes. J Neurosci Res (2008) 1.04
Presenilin-dependent gamma-secretase on plasma membrane and endosomes is functionally distinct. Biochemistry (2006) 1.04
Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum. PLoS One (2011) 1.03
Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun (2012) 1.03
Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an apolipoprotein E receptor/disabled-1/glycogen synthase kinase-3beta cascade. FASEB J (2002) 1.03
The neurotrophin receptor p75NTR in Schwann cells is implicated in remyelination and motor recovery after peripheral nerve injury. Glia (2007) 1.03
Characterization of cells with proliferative activity after a brain injury. Neurochem Int (2005) 1.02
Chondroitin sulfate N-acetylgalactosaminyltransferase 1 is necessary for normal endochondral ossification and aggrecan metabolism. J Biol Chem (2010) 1.01
Hyperactivation of midbrain dopaminergic system in schizophrenia could be attributed to the down-regulation of dysbindin. Biochem Biophys Res Commun (2006) 1.01
Role of endoplasmic reticulum stress in light-induced photoreceptor degeneration in mice. J Neurochem (2013) 1.01