Published in Science on July 01, 2005
Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa. PLoS Pathog (2007) 3.27
A Plasmodium whole-genome synteny map: indels and synteny breakpoints as foci for species-specific genes. PLoS Pathog (2005) 2.05
A unique dual activity amino acid hydroxylase in Toxoplasma gondii. PLoS One (2009) 1.74
Genomic survey of the non-cultivatable opportunistic human pathogen, Enterocytozoon bieneusi. PLoS Pathog (2009) 1.73
Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum. PLoS Biol (2009) 1.72
Complete nucleotide sequence of the chlorarachniophyte nucleomorph: nature's smallest nucleus. Proc Natl Acad Sci U S A (2006) 1.70
A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions. Mol Biol Cell (2006) 1.59
HDP-a novel heme detoxification protein from the malaria parasite. PLoS Pathog (2008) 1.55
Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti. Nucleic Acids Res (2012) 1.49
The Apicomplexan whole-genome phylogeny: an analysis of incongruence among gene trees. Mol Biol Evol (2008) 1.48
Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast. EMBO J (2006) 1.42
Bioinformatic identification of tandem repeat antigens of the Leishmania donovani complex. Infect Immun (2006) 1.27
Hemizygous subtelomeres of an African trypanosome chromosome may account for over 75% of chromosome length. Genome Res (2006) 1.24
Suggestive evidence for Darwinian Selection against asparagine-linked glycans of Plasmodium falciparum and Toxoplasma gondii. Eukaryot Cell (2009) 1.20
Horizontal gene transfer in eukaryotes: the weak-link model. Bioessays (2013) 1.15
Scavenging of the cofactor lipoate is essential for the survival of the malaria parasite Plasmodium falciparum. Mol Microbiol (2007) 1.14
Genome-wide analysis of the diatom cell cycle unveils a novel type of cyclins involved in environmental signaling. Genome Biol (2010) 1.12
Plasticity of the Hsp90 chaperone machine in divergent eukaryotic organisms. Cell Stress Chaperones (2008) 1.11
Jumbled genomes: missing Apicomplexan synteny. Mol Biol Evol (2011) 1.11
Consistent and contrasting properties of lineage-specific genes in the apicomplexan parasites Plasmodium and Theileria. BMC Evol Biol (2008) 1.09
Inconsistencies of genome annotations in apicomplexan parasites revealed by 5'-end-one-pass and full-length sequences of oligo-capped cDNAs. BMC Genomics (2009) 1.08
Whole-genome analysis reveals molecular innovations and evolutionary transitions in chromalveolate species. Proc Natl Acad Sci U S A (2008) 1.08
Comparative genomics of the Rab protein family in Apicomplexan parasites. Microbes Infect (2008) 1.06
Large-scale intron conservation and order-of-magnitude variation in intron loss/gain rates in apicomplexan evolution. Genome Res (2006) 1.05
The origins of apicomplexan sequence innovation. Genome Res (2009) 1.03
The apicomplexan plastid and its evolution. Cell Mol Life Sci (2011) 1.03
Evolution and diversity of secretome genes in the apicomplexan parasite Theileria annulata. BMC Genomics (2010) 1.02
Expression analysis of the Theileria parva subtelomere-encoded variable secreted protein gene family. PLoS One (2009) 0.99
Structural and evolutionary divergence of eukaryotic protein kinases in Apicomplexa. BMC Evol Biol (2011) 0.98
Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major. BMC Genomics (2010) 0.98
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Comparative genomic analysis and phylogenetic position of Theileria equi. BMC Genomics (2012) 0.97
Toxoplasma gondii expresses two mitogen-activated protein kinase genes that represent distinct protozoan subfamilies. J Mol Evol (2006) 0.96
Highly divergent mitochondrial ATP synthase complexes in Tetrahymena thermophila. PLoS Biol (2010) 0.96
Theileria apicoplast as a target for chemotherapy. Antimicrob Agents Chemother (2008) 0.95
In silico identification of specialized secretory-organelle proteins in apicomplexan parasites and in vivo validation in Toxoplasma gondii. PLoS One (2008) 0.95
Recruitment of EB1, a master regulator of microtubule dynamics, to the surface of the Theileria annulata schizont. PLoS Pathog (2013) 0.95
Library of Apicomplexan Metabolic Pathways: a manually curated database for metabolic pathways of apicomplexan parasites. Nucleic Acids Res (2012) 0.94
Phylogenomic analyses of malaria parasites and evolution of their exported proteins. BMC Evol Biol (2011) 0.89
Is human giardiasis caused by two different Giardia species? Gut Microbes (2011) 0.88
Conservation and divergence of known apicomplexan transcriptional regulons. BMC Genomics (2010) 0.88
Genetics. Themes and variations in apicomplexan parasite biology. Science (2005) 0.88
Whole genome mapping and re-organization of the nuclear and mitochondrial genomes of Babesia microti isolates. PLoS One (2013) 0.88
Development of a multiplex PCR assay for simultaneous detection of Theileria annulata, Babesia bovis and Anaplasma marginale in cattle. Exp Parasitol (2012) 0.87
From molecule to diagnostic tool: Theileria annulata surface protein TaSP. Parasitol Res (2007) 0.87
Analysis of the spatial and temporal arrangement of transcripts over intergenic regions in the human malarial parasite Plasmodium falciparum. BMC Genomics (2013) 0.87
Horizontal gene transfer is a significant driver of gene innovation in dinoflagellates. Genome Biol Evol (2013) 0.87
Molecular parasitology in the 21st century. Essays Biochem (2011) 0.87
Extensive polymorphism and evidence of immune selection in a highly dominant antigen recognized by bovine CD8 T cells specific for Theileria annulata. Infect Immun (2011) 0.87
Apicomplexan perforin-like proteins. Commun Integr Biol (2010) 0.85
Construction of a genetic map for Theileria parva: identification of hotspots of recombination. Int J Parasitol (2011) 0.84
ApiAP2 Factors as Candidate Regulators of Stochastic Commitment to Merozoite Production in Theileria annulata. PLoS Negl Trop Dis (2015) 0.84
Demonstration of strain-specific CD8 T cell responses to Theileria annulata. Parasite Immunol (2008) 0.83
Differential expression of three members of the multidomain adhesion CCp family in Babesia bigemina, Babesia bovis and Theileria equi. PLoS One (2013) 0.83
Properties of non-coding DNA and identification of putative cis-regulatory elements in Theileria parva. BMC Genomics (2008) 0.83
Genome cartography: charting the apicomplexan genome. Trends Parasitol (2011) 0.83
Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation. Nature (2015) 0.82
Protein coding gene nucleotide substitution pattern in the apicomplexan protozoa Cryptosporidium parvum and Cryptosporidium hominis. Comp Funct Genomics (2008) 0.82
Whole-genome sequencing of Theileria parva strains provides insight into parasite migration and diversification in the African continent. DNA Res (2013) 0.82
Comparative genomics of cryptosporidium. Int J Genomics (2013) 0.81
Proteomic analysis of the Theileria annulata schizont. Int J Parasitol (2012) 0.81
RPS8--a new informative DNA marker for phylogeny of Babesia and Theileria parasites in China. PLoS One (2013) 0.81
The parasite specific substitution matrices improve the annotation of apicomplexan proteins. BMC Genomics (2012) 0.80
Genome-wide analysis of peptidase content and expression in a virulent and attenuated Babesia bovis strain pair. Mol Biochem Parasitol (2011) 0.80
Large, rapidly evolving gene families are at the forefront of host-parasite interactions in Apicomplexa. Parasitology (2014) 0.80
The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence. BMC Genomics (2015) 0.80
A large-scale proteogenomics study of apicomplexan pathogens-Toxoplasma gondii and Neospora caninum. Proteomics (2015) 0.80
Characterisation of gp34, a GPI-anchored protein expressed by schizonts of Theileria parva and T. annulata. Mol Biochem Parasitol (2010) 0.79
Cis regulatory motifs and antisense transcriptional control in the apicomplexan Theileria parva. BMC Genomics (2016) 0.79
Targeting NAD+ metabolism in the human malaria parasite Plasmodium falciparum. PLoS One (2014) 0.79
A quantitative reverse-transcriptase PCR assay for the assessment of drug activities against intracellular Theileria annulata schizonts. Int J Parasitol Drugs Drug Resist (2014) 0.79
Molecular characterization of a Theileria lestoquardi gene encoding for immunogenic protein splice variants. Parasitol Res (2006) 0.79
Cloning and characterization of telomerase reverse transcriptase gene in Trichinella spiralis. Parasitol Res (2011) 0.78
The role played by alternative splicing in antigenic variability in human endo-parasites. Parasit Vectors (2014) 0.78
Plant-type trehalose synthetic pathway in cryptosporidium and some other apicomplexans. PLoS One (2010) 0.78
kdetrees: Non-parametric estimation of phylogenetic tree distributions. Bioinformatics (2014) 0.78
High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing. BMC Genomics (2012) 0.78
Revisiting the reference genomes of human pathogenic Cryptosporidium species: reannotation of C. parvum Iowa and a new C. hominis reference. Sci Rep (2015) 0.78
The Plastid Genome of the Cryptomonad Teleaulax amphioxeia. PLoS One (2015) 0.78
The protozoan parasite Theileria annulata alters the differentiation state of the infected macrophage and suppresses musculoaponeurotic fibrosarcoma oncogene (MAF) transcription factors. Int J Parasitol (2009) 0.78
Molecular cloning and phylogenetic analysis of Clonorchis sinensis elongation factor-1alpha. Parasitol Res (2007) 0.77
Babesia bovis: a bipartite signal directs the glutamyl-tRNA synthetase to the apicoplast. Exp Parasitol (2012) 0.77
Bovipain-2, the falcipain-2 ortholog, is expressed in intraerythrocytic stages of the tick-transmitted hemoparasite Babesia bovis. Parasit Vectors (2010) 0.77
TparvaDB: a database to support Theileria parva vaccine development. Database (Oxford) (2011) 0.76
Plasmodium Apicoplast Gln-tRNAGln Biosynthesis Utilizes a Unique GatAB Amidotransferase Essential for Erythrocytic Stage Parasites. J Biol Chem (2015) 0.76
Comparative transcriptome profiling approach to glean virulence and immunomodulation-related genes of Fasciola hepatica. BMC Genomics (2015) 0.76
A survey of innovation through duplication in the reduced genomes of twelve parasites. PLoS One (2014) 0.76
Identification and Analysis of Immunodominant Antigens for ELISA-Based Detection of Theileria annulata. PLoS One (2016) 0.75
Approaches to vaccination against Theileria parva and Theileria annulata. Parasite Immunol (2016) 0.75
Cell cycle-dependent phosphorylation of Theileria annulata schizont surface proteins. PLoS One (2014) 0.75
The protein subunit of telomerase displays patterns of dynamic evolution and conservation across different metazoan taxa. BMC Evol Biol (2017) 0.75
Characterization of HSP90 isoforms in transformed bovine leukocytes infected with Theileria annulata. Cell Microbiol (2016) 0.75
Improved orthologous databases to ease protozoan targets inference. Parasit Vectors (2015) 0.75
The Microtubule-Stabilizing Protein CLASP1 Associates with the Theileria annulata Schizont Surface via Its Kinetochore-Binding Domain. mSphere (2017) 0.75
Genome microsatellite diversity within the Apicomplexa phylum. Mol Genet Genomics (2016) 0.75
The Pfam protein families database. Nucleic Acids Res (2004) 56.46
The Pfam protein families database. Nucleic Acids Res (2002) 51.34
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat Genet (2008) 43.63
Genome sequence of the human malaria parasite Plasmodium falciparum. Nature (2002) 37.89
Pfam: clans, web tools and services. Nucleic Acids Res (2006) 34.83
miRBase: integrating microRNA annotation and deep-sequencing data. Nucleic Acids Res (2010) 25.85
The InterPro Database, 2003 brings increased coverage and new features. Nucleic Acids Res (2003) 24.72
A uniform system for microRNA annotation. RNA (2003) 20.28
Evolution of genes and genomes on the Drosophila phylogeny. Nature (2007) 18.01
ACT: the Artemis Comparison Tool. Bioinformatics (2005) 17.91
Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell (2011) 16.72
Accurate determination of microbial diversity from 454 pyrosequencing data. Nat Methods (2009) 15.25
Identification of mammalian microRNA host genes and transcription units. Genome Res (2004) 14.63
Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature (2009) 13.45
miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Res (2013) 13.41
Evolution of MRSA during hospital transmission and intercontinental spread. Science (2010) 13.34
The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol (2003) 13.32
The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature (2010) 12.43
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Population genomics of domestic and wild yeasts. Nature (2009) 11.79
Rfam: updates to the RNA families database. Nucleic Acids Res (2008) 11.61
The genome of the African trypanosome Trypanosoma brucei. Science (2005) 11.48
Genome evolution in yeasts. Nature (2004) 10.50
Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of (G+C)-biased genomes. Nat Methods (2009) 10.41
Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database. Bioinformatics (2008) 9.17
Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nat Genet (2003) 9.13
Rapid pneumococcal evolution in response to clinical interventions. Science (2011) 9.09
Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci U S A (2004) 8.95
The genome of the kinetoplastid parasite, Leishmania major. Science (2005) 8.64
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature (2005) 8.55
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths. PLoS Genet (2009) 8.51
Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6. Lancet (2005) 8.30
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM. Nat Methods (2013) 8.12
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet (2006) 8.02