Published in Oncogene on October 20, 2005
Subcellular relocalization of a trans-acting factor regulates XIAP IRES-dependent translation. Mol Biol Cell (2007) 1.50
Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights. Pharmacol Ther (2014) 1.35
Butyrate mediates decrease of histone acetylation centered on transcription start sites and down-regulation of associated genes. Genome Res (2007) 1.35
Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist. Proc Natl Acad Sci U S A (2008) 1.33
Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo. Mol Cancer (2006) 1.03
c-FLIP degradation mediates sensitization of pancreatic cancer cells to TRAIL-induced apoptosis by the histone deacetylase inhibitor LBH589. PLoS One (2010) 1.01
Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. Exp Cell Res (2014) 0.88
Paxilline enhances TRAIL-mediated apoptosis of glioma cells via modulation of c-FLIP, survivin and DR5. Exp Mol Med (2011) 0.88
Molecular analysis of sunitinib resistant renal cell carcinoma cells after sequential treatment with RAD001 (everolimus) or sorafenib. J Cell Mol Med (2014) 0.81
Tunicamycin enhances TRAIL-induced apoptosis by inhibition of cyclin D1 and the subsequent downregulation of survivin. Exp Mol Med (2009) 0.77
Determination of the Role of CBP- and p300-Mediated Wnt Signaling on Colonic Cells. JMIR Res Protoc (2016) 0.77
Marine Drugs Regulating Apoptosis Induced by Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL). Mar Drugs (2015) 0.75
NVP-BKM120 potentiates apoptosis in tumor necrosis factor-related apoptosis-inducing ligand-resistant glioma cell lines via upregulation of Noxa and death receptor 5. Int J Oncol (2015) 0.75
Epigenetic modifications in cell lines of human astrocytoma differentially regulate expression of apoptotic genes. Childs Nerv Syst (2013) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Prospects of colloidal nanocrystals for electronic and optoelectronic applications. Chem Rev (2010) 4.03
Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke. Brain (2007) 3.68
An HDAC inhibitor, trichostatin A, induces a delay at G2/M transition, slippage of spindle checkpoint, and cell death in a transcription-dependent manner. Biochem Biophys Res Commun (2008) 2.48
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proc Natl Acad Sci U S A (2007) 2.19
Atmospheric-pressure plasma jet induces apoptosis involving mitochondria via generation of free radicals. PLoS One (2011) 2.00
Human neural stem cell transplantation promotes functional recovery in rats with experimental intracerebral hemorrhage. Stroke (2003) 1.97
Regulation of singlet oxygen-induced apoptosis by cytosolic NADP+-dependent isocitrate dehydrogenase. Mol Cell Biochem (2007) 1.95
Corneal epithelial cellular dysfunction from benzalkonium chloride (BAC) in vitro. Clin Experiment Ophthalmol (2004) 1.77
Neural stem cell tropism to glioma: critical role of tumor hypoxia. Mol Cancer Res (2008) 1.67
Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease. J Neurosci (2006) 1.59
Two distinct modes of cell death induced by doxorubicin: apoptosis and cell death through mitotic catastrophe accompanied by senescence-like phenotype. Oncogene (2005) 1.57
Brain transplantation of immortalized human neural stem cells promotes functional recovery in mouse intracerebral hemorrhage stroke model. Stem Cells (2007) 1.57
Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia. Brain Res (2004) 1.55
Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5. Cancer Res (2006) 1.47
Development of a tumor-selective approach to treat metastatic cancer. PLoS One (2006) 1.46
Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells. Cancer Res (2007) 1.45
Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression. Clin Cancer Res (2006) 1.44
Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus. Neurobiol Dis (2006) 1.43
Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies. Sci Transl Med (2013) 1.42
Brain tumor tropism of transplanted human neural stem cells is induced by vascular endothelial growth factor. Neoplasia (2005) 1.41
Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model. PLoS One (2007) 1.41
Cytokines, chemokines, and cytokine receptors in human microglia. J Neurosci Res (2002) 1.39
Human neural stem cells can migrate, differentiate, and integrate after intravenous transplantation in adult rats with transient forebrain ischemia. Neurosci Lett (2003) 1.39
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma. Cancer Res (2007) 1.38
TGF beta1 induces prolonged mitochondrial ROS generation through decreased complex IV activity with senescent arrest in Mv1Lu cells. Oncogene (2005) 1.38
Targeting rat brainstem glioma using human neural stem cells and human mesenchymal stem cells. Clin Cancer Res (2009) 1.38
The histone deacetylase inhibitor trichostatin A sensitizes estrogen receptor alpha-negative breast cancer cells to tamoxifen. Oncogene (2004) 1.38
Elimination of lymphatic filariasis in the Republic of Korea: an epidemiological survey of formerly endemic areas, 2002-2006. Trop Med Int Health (2009) 1.37
Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model. PLoS One (2009) 1.36
Metal-free inorganic ligands for colloidal nanocrystals: S2-, HS-, Se2-, HSe-, Te2-, HTe-, TeS3(2-), OH-, and NH2- as surface ligands. J Am Chem Soc (2011) 1.35
Chronic cerebral paragonimiasis combined with aneurysmal subarachnoid hemorrhage. Am J Trop Med Hyg (2003) 1.35
Fractalkine and fractalkine receptors in human neurons and glial cells. J Neurosci Res (2002) 1.32
Viral Bcl-2-mediated evasion of autophagy aids chronic infection of gammaherpesvirus 68. PLoS Pathog (2009) 1.31
Urokinase plasminogen activator and urokinase plasminogen activator receptor mediate human stem cell tropism to malignant solid tumors. Stem Cells (2008) 1.30
Transplantation of human mesenchymal stem cells promotes functional improvement and increased expression of neurotrophic factors in a rat focal cerebral ischemia model. J Neurosci Res (2010) 1.30
Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5). Carcinogenesis (2005) 1.23
Physiological Functionality and Enzyme Activity of Biomass from Pichia anomala Grown on Ginseng-Steaming Effluent. Mycobiology (2008) 1.22
Minocycline inhibits neuronal death and glial activation induced by beta-amyloid peptide in rat hippocampus. Glia (2004) 1.21
Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain. J Neurosci (2007) 1.21
A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. Cancer Res (2007) 1.19
Intravenously transplanted human neural stem cells migrate to the injured spinal cord in adult mice in an SDF-1- and HGF-dependent manner. Neurosci Lett (2007) 1.18
Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP. Oncogene (2004) 1.18
IL-8 enhancement of amyloid-beta (Abeta 1-42)-induced expression and production of pro-inflammatory cytokines and COX-2 in cultured human microglia. J Neuroimmunol (2004) 1.17
Autophagy protein Rubicon mediates phagocytic NADPH oxidase activation in response to microbial infection or TLR stimulation. Cell Host Microbe (2012) 1.16
Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation. J Cell Biochem (2008) 1.16
Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage. Mol Cancer Res (2003) 1.15
Stem cell-based cell therapy for spinal cord injury. Cell Transplant (2007) 1.15
Ex vivo VEGF delivery by neural stem cells enhances proliferation of glial progenitors, angiogenesis, and tissue sparing after spinal cord injury. PLoS One (2009) 1.15
Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease. Neurobiol Dis (2004) 1.15
Transmodulation between phospholipase D and c-Src enhances cell proliferation. Mol Cell Biol (2003) 1.15
Neural progenitor NT2N cell lines from teratocarcinoma for transplantation therapy in stroke. Prog Neurobiol (2008) 1.15
A mark-release-recapture experiment with Anopheles sinensis in the northern part of Gyeonggi-do, Korea. Korean J Parasitol (2002) 1.14
Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation. Clin Cancer Res (2004) 1.14
Multilineage potential of stable human mesenchymal stem cell line derived from fetal marrow. PLoS One (2007) 1.14
Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk. J Ethnopharmacol (2007) 1.14
Transplantation of human neural stem cells transduced with Olig2 transcription factor improves locomotor recovery and enhances myelination in the white matter of rat spinal cord following contusive injury. BMC Neurosci (2009) 1.13
Human neural stem cell tropism to metastatic breast cancer. Stem Cells (2012) 1.13
Ecology of H3 avian influenza viruses in Korea and assessment of their pathogenic potentials. J Gen Virol (2008) 1.13
Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic Biol Med (2009) 1.13
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis. Semin Cancer Biol (2008) 1.13
Characterisation of a new antihypertensive angiotensin I-converting enzyme inhibitory peptide from Pleurotus cornucopiae. Food Chem (2011) 1.13
Upregulation of protease-activated receptor-1 in astrocytes in Parkinson disease: astrocyte-mediated neuroprotection through increased levels of glutathione peroxidase. J Neuropathol Exp Neurol (2006) 1.12
Inhibition of lipopolysaccharide-induced cyclooxygenase-2, tumor necrosis factor-alpha and [Ca2+]i responses in human microglia by the peripheral benzodiazepine receptor ligand PK11195. J Neurochem (2002) 1.12
Expanding the chemical versatility of colloidal nanocrystals capped with molecular metal chalcogenide ligands. J Am Chem Soc (2010) 1.12
Mithramycin A sensitizes cancer cells to TRAIL-mediated apoptosis by down-regulation of XIAP gene promoter through Sp1 sites. Mol Cancer Ther (2006) 1.11
Inhibition of thrombin-induced microglial activation and NADPH oxidase by minocycline protects dopaminergic neurons in the substantia nigra in vivo. J Neurochem (2005) 1.11
Human neural stem cells genetically modified to overexpress brain-derived neurotrophic factor promote functional recovery and neuroprotection in a mouse stroke model. J Neurosci Res (2010) 1.11
Granulocyte colony-stimulating factor stimulates neurogenesis via vascular endothelial growth factor with STAT activation. Brain Res (2006) 1.10
Characterization of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitor from Pueraria thunbergiana. J Agric Food Chem (2005) 1.10
Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro. J Neurosci (2005) 1.10
Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction. Exp Neurol (2012) 1.09
Rottlerin induces apoptosis via death receptor 5 (DR5) upregulation through CHOP-dependent and PKC delta-independent mechanism in human malignant tumor cells. Carcinogenesis (2008) 1.09
Analyses of enzyme II gene mutants for sugar transport and heterologous expression of fructokinase gene in Corynebacterium glutamicum ATCC 13032. FEMS Microbiol Lett (2005) 1.09
Neural stem cell targeting of glioma is dependent on phosphoinositide 3-kinase signaling. Stem Cells (2008) 1.09
Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model. Neurosci Res (2005) 1.09
KSHV-induced notch components render endothelial and mural cell characteristics and cell survival. Blood (2009) 1.09
PEX-producing human neural stem cells inhibit tumor growth in a mouse glioma model. Clin Cancer Res (2005) 1.08
Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice. Neurobiol Aging (2003) 1.08
Adenosine triphosphate induces proliferation of human neural stem cells: Role of calcium and p70 ribosomal protein S6 kinase. J Neurosci Res (2003) 1.08
Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo. J Neurosci (2003) 1.08
Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia. J Neurosci (2006) 1.07
Magnetic resonance imaging tracking of ferumoxytol-labeled human neural stem cells: studies leading to clinical use. Stem Cells Transl Med (2013) 1.07
Viral interferon regulatory factors. J Interferon Cytokine Res (2009) 1.07
Human microglial cells synthesize albumin in brain. PLoS One (2008) 1.07
In vivo animal stroke models: a rationale for rodent and non-human primate models. Transl Stroke Res (2013) 1.07
Human microglia transplanted in rat focal ischemia brain induce neuroprotection and behavioral improvement. PLoS One (2010) 1.07
Non-human primate model of Kaposi's sarcoma-associated herpesvirus infection. PLoS Pathog (2009) 1.06
Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies. PLoS One (2009) 1.05
Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin. Cancer Res (2007) 1.05
Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation. Cancer Res (2008) 1.04
The autophagy regulator Rubicon is a feedback inhibitor of CARD9-mediated host innate immunity. Cell Host Microbe (2012) 1.04
Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP. Free Radic Biol Med (2007) 1.04
Transforming growth factor beta 1 induces apoptosis through cleavage of BAD in a Smad3-dependent mechanism in FaO hepatoma cells. Mol Cell Biol (2002) 1.04
A survey of Brugia malayi infection on the Heugsan Islands, Korea. Korean J Parasitol (2003) 1.04
Superoxide anion and proteasomal dysfunction contribute to curcumin-induced paraptosis of malignant breast cancer cells. Free Radic Biol Med (2009) 1.04