Published in J Neurosci on July 13, 2005
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp Neurol (2007) 3.06
Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury. J Comp Neurol (2006) 1.84
Inducible protein-10, a potential driver of neurally controlled interleukin-10 and morbidity in human blunt trauma. Crit Care Med (2014) 1.57
CNS-infiltrating CD4+ T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain. Eur J Immunol (2008) 1.51
Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. Proc Natl Acad Sci U S A (2006) 1.50
Inflammation and Spinal Cord Injury: Infiltrating Leukocytes as Determinants of Injury and Repair Processes. Clin Neurosci Res (2006) 1.24
PPAR Regulation of Inflammatory Signaling in CNS Diseases. PPAR Res (2008) 1.11
Inflammatory reaction after traumatic brain injury: therapeutic potential of targeting cell-cell communication by chemokines. Trends Pharmacol Sci (2015) 1.09
The paradox of chronic neuroinflammation, systemic immune suppression, autoimmunity after traumatic chronic spinal cord injury. Exp Neurol (2014) 1.02
Characterization of early and terminal complement proteins associated with polymorphonuclear leukocytes in vitro and in vivo after spinal cord injury. J Neuroinflammation (2008) 0.93
Quantitative assessment of immune cells in the injured spinal cord tissue by flow cytometry: a novel use for a cell purification method. J Vis Exp (2011) 0.92
Transcriptomic screening of microvascular endothelial cells implicates novel molecular regulators of vascular dysfunction after spinal cord injury. J Cereb Blood Flow Metab (2008) 0.90
Microglial responses around intrinsic CNS neurons are correlated with axonal regeneration. BMC Neurosci (2010) 0.89
Effects of Olig2-overexpressing neural stem cells and myelin basic protein-activated T cells on recovery from spinal cord injury. Neurotherapeutics (2012) 0.86
Syndromics: a bioinformatics approach for neurotrauma research. Transl Stroke Res (2011) 0.86
Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate. Cell Mol Life Sci (2014) 0.85
Chemokines as possible targets in modulation of the secondary damage after acute spinal cord injury: a review. Cell Mol Neurobiol (2009) 0.85
Role of secretory phospholipase a(2) in CNS inflammation: implications in traumatic spinal cord injury. CNS Neurol Disord Drug Targets (2008) 0.84
Cyclosporin A increases recovery after spinal cord injury but does not improve myelination by oligodendrocyte progenitor cell transplantation. BMC Neurosci (2010) 0.81
The PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice. Exp Neurol (2011) 0.80
Traumatic spinal cord injury in mice with human immune systems. Exp Neurol (2015) 0.77
Neuron specific enolase: a promising therapeutic target in acute spinal cord injury. Metab Brain Dis (2016) 0.76
B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury. Neurotherapeutics (2016) 0.75
T cell deficiency in spinal cord injury: altered locomotor recovery and whole-genome transcriptional analysis. BMC Neurosci (2015) 0.75
Product differentiation by analysis of DNA melting curves during the polymerase chain reaction. Anal Biochem (1997) 7.72
Fibrotic disease and the T(H)1/T(H)2 paradigm. Nat Rev Immunol (2004) 6.75
IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J Immunol (2002) 4.81
The role of chemokine receptors in primary, effector, and memory immune responses. Annu Rev Immunol (2000) 4.78
Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol Today (1998) 4.21
Chemokines: multiple levels of leukocyte migration control. Trends Immunol (2004) 3.32
Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest (1999) 3.21
Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J Exp Med (2000) 3.15
CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions. Proc Natl Acad Sci U S A (1999) 3.07
Cellular inflammatory response after spinal cord injury in Sprague-Dawley and Lewis rats. J Comp Neurol (1997) 3.06
Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury. Exp Neurol (1999) 2.78
Activation of dual T cell signaling pathways by the chemokine RANTES. Science (1995) 2.65
Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages. J Exp Med (1990) 2.42
Homing to central nervous system vasculature by antigen-specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis. Lab Invest (1990) 2.03
Traumatic spinal cord injury produced by controlled contusion in mouse. J Neurotrauma (2000) 1.97
Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligand. Proc Natl Acad Sci U S A (1997) 1.95
Rats and mice exhibit distinct inflammatory reactions after spinal cord injury. J Comp Neurol (2003) 1.94
Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. J Immunol (1998) 1.91
The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis. J Exp Med (2004) 1.90
Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain. J Immunol (1996) 1.84
A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry. Proc Natl Acad Sci U S A (1996) 1.68
Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation. Immunol Rev (2000) 1.61
Neuroprotection by encephalomyelitis: rescue of mechanically injured neurons and neurotrophin production by CNS-infiltrating T and natural killer cells. J Neurosci (2000) 1.44
Lymphocyte function in wound healing and following injury. Br J Surg (1998) 1.42
Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning. Trends Pharmacol Sci (1999) 1.42
Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury. Exp Neurol (2003) 1.35
Expression of pro-inflammatory cytokine and chemokine mRNA upon experimental spinal cord injury in mouse: an in situ hybridization study. Eur J Neurosci (1997) 1.33
Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy. J Neurosci (2002) 1.33
Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion. J Neurosci Res (2002) 1.23
Protective autoimmunity: regulation and prospects for vaccination after brain and spinal cord injuries. Trends Mol Med (2001) 1.22
TGF-beta 1 is an organizer of responses to neurodegeneration. J Cell Biochem (1993) 1.22
Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis. J Immunol (2003) 1.21
Effects of transforming growth factor beta 1 on scar production in the injured central nervous system of the rat. Eur J Neurosci (1994) 1.20
Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury. J Neurosci Res (1998) 1.19
Inhibition of monocyte/macrophage migration to a spinal cord injury site by an antibody to the integrin alphaD: a potential new anti-inflammatory treatment. Exp Neurol (2000) 1.18
Ccr2 regulates the level of MCP-1/CCL2 in vitro and at inflammatory sites and controls T cell activation in response to alloantigen. Cytokine (2002) 1.18
Morphological aspects of spinal cord autoimmune neuroprotection: colocalization of T cells with B7--2 (CD86) and prevention of cyst formation. FASEB J (2001) 1.17
Effects of silica on the outcome from experimental spinal cord injury: implication of macrophages in secondary tissue damage. Neuroscience (1994) 1.16
Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc. J Exp Med (1999) 1.14
Ascending sensory, but not other long-tract axons, regenerate into the connective tissue matrix that forms at the site of a spinal cord injury in mice. J Comp Neurol (2003) 1.10
The effect of in vivo T helper and T suppressor lymphocyte depletion on wound healing. Ann Surg (1989) 1.10
Expression of TGFbeta2 but not TGFbeta1 correlates with the deposition of scar tissue in the lesioned spinal cord. Mol Cell Neurosci (2002) 1.09
Enhanced axonal growth into a spinal cord contusion injury site in a strain of mouse (129X1/SvJ) with a diminished inflammatory response. J Comp Neurol (2004) 1.08
Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats. J Neurosci (2004) 1.07
RANTES activates antigen-specific cytotoxic T lymphocytes in a mitogen-like manner through cell surface aggregation. Int Immunol (2000) 1.03
Leukocyte infiltration, but not neurodegeneration, in the CNS of transgenic mice with astrocyte production of the CXC chemokine ligand 10. J Immunol (2002) 1.03
Neuronal control of MHC class II inducibility in rat astrocytes and microglia. Eur J Neurosci (1996) 1.01
Wound healing and T-lymphocytes. J Surg Res (1990) 1.00
Myelin specific Th1 cells are necessary for post-traumatic protective autoimmunity. J Neuroimmunol (2002) 0.98
Wound healing in nude mice: a study on the regulatory role of lymphocytes in fibroplasia. Surgery (1989) 0.97
The insulin-like growth factor-I receptor is regulated by CD28 and protects activated T cells from apoptosis. Eur J Immunol (2000) 0.93
Differential expression of neurotrophic factors and inflammatory cytokines by myelin basic protein-specific and other recruited T cells infiltrating the central nervous system during experimental autoimmune encephalomyelitis. Scand J Immunol (2002) 0.90
Localization of transforming growth factor-beta1 and receptor mRNA after experimental spinal cord injury. Exp Neurol (2000) 0.89
Immunological regulation of neuronal degeneration and regeneration in the injured spinal cord. Prog Brain Res (2000) 0.88
Insulin-like growth factor-II increases and IGF is required for postnatal rat spinal motoneuron survival following sciatic nerve axotomy. J Neurosci Res (1999) 0.87
Adenovirus-mediated expression of CXCL10 in the central nervous system results in T-cell recruitment and limited neuropathology. J Neurovirol (2003) 0.82
Presence of B7--2 (CD86) and lack of B7--1 (CD(80) on myelin phagocytosing MHC-II-positive rat microglia is associated with nondestructive immunity in vivo. FASEB J (2001) 0.82
Peripherally administered insulin-like growth factor-I preserves hindlimb reflex and spinal cord noradrenergic circuitry following a central nervous system lesion in rats. Exp Neurol (1999) 0.81
Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J Neurosci (2009) 6.93
Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. J Neurotrauma (2006) 5.32
Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury. Exp Neurol (2007) 3.06
Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife (2013) 2.66
Replication and reproducibility in spinal cord injury research. Exp Neurol (2011) 2.31
Differential regulation of microRNA stability. RNA (2010) 2.24
Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury. J Neuroinflammation (2011) 2.02
Rats and mice exhibit distinct inflammatory reactions after spinal cord injury. J Comp Neurol (2003) 1.94
Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J Neurochem (2007) 1.92
Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury. J Comp Neurol (2006) 1.84
Macrophages promote axon regeneration with concurrent neurotoxicity. J Neurosci (2009) 1.80
Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. PLoS One (2009) 1.70
MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells. Stem Cells Dev (2007) 1.65
Deficient CX3CR1 signaling promotes recovery after mouse spinal cord injury by limiting the recruitment and activation of Ly6Clo/iNOS+ macrophages. J Neurosci (2011) 1.59
In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat. J Pharmacol Exp Ther (2004) 1.53
Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation. Exp Neurol (2007) 1.52
An efficient and reproducible method for quantifying macrophages in different experimental models of central nervous system pathology. J Neurosci Methods (2009) 1.48
Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats. Exp Neurol (2008) 1.46
Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nat Med (2012) 1.42
B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice. J Clin Invest (2009) 1.37
Neuroinflammation in spinal cord injury: therapeutic targets for neuroprotection and regeneration. Prog Brain Res (2009) 1.35
Inflammation and axon regeneration. Curr Opin Neurol (2011) 1.33
Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome. Proc Natl Acad Sci U S A (2010) 1.33
Pathological CNS autoimmune disease triggered by traumatic spinal cord injury: implications for autoimmune vaccine therapy. J Neurosci (2002) 1.33
Concise review: MicroRNA expression in multipotent mesenchymal stromal cells. Stem Cells (2007) 1.32
Rational probe optimization and enhanced detection strategy for microRNAs using microarrays. RNA Biol (2005) 1.31
Characterization and modeling of monocyte-derived macrophages after spinal cord injury. J Neurochem (2007) 1.28
Intrinsic differences in brain and spinal cord mitochondria: Implication for therapeutic interventions. J Comp Neurol (2004) 1.26
Spinal cord injury triggers systemic autoimmunity: evidence for chronic B lymphocyte activation and lupus-like autoantibody synthesis. J Neurochem (2006) 1.25
Fractalkine receptor (CX3CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide. J Neuroinflammation (2010) 1.24
Evaluation of sense-strand mRNA amplification by comparative quantitative PCR. BMC Genomics (2004) 1.22
Stress exacerbates neuropathic pain via glucocorticoid and NMDA receptor activation. Brain Behav Immun (2009) 1.18
Progranulin expression is upregulated after spinal contusion in mice. Acta Neuropathol (2009) 1.17
Oligodendrocyte generation is differentially influenced by toll-like receptor (TLR) 2 and TLR4-mediated intraspinal macrophage activation. J Neuropathol Exp Neurol (2007) 1.15
A grading system to evaluate objectively the strength of pre-clinical data of acute neuroprotective therapies for clinical translation in spinal cord injury. J Neurotrauma (2010) 1.13
Expression profiling of synaptic microRNAs from the adult rat brain identifies regional differences and seizure-induced dynamic modulation. Brain Res (2011) 1.11
Stress hormones collaborate to induce lymphocyte apoptosis after high level spinal cord injury. J Neurochem (2009) 1.11
MicroRNA miR-133b is essential for functional recovery after spinal cord injury in adult zebrafish. Eur J Neurosci (2011) 1.10
Cytokine activity contributes to induction of inflammatory cytokine mRNAs in spinal cord following contusion. J Neurosci Res (2002) 1.10
Autonomic dysreflexia causes chronic immune suppression after spinal cord injury. J Neurosci (2013) 1.07
Passive or active immunization with myelin basic protein impairs neurological function and exacerbates neuropathology after spinal cord injury in rats. J Neurosci (2004) 1.07
MICAL flavoprotein monooxygenases: expression during neural development and following spinal cord injuries in the rat. Mol Cell Neurosci (2005) 1.07
EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia. Nat Neurosci (2013) 1.06
B cells and autoantibodies: complex roles in CNS injury. Trends Immunol (2010) 1.05
Semi-automated Sholl analysis for quantifying changes in growth and differentiation of neurons and glia. J Neurosci Methods (2010) 1.05
Minimum information about a spinal cord injury experiment: a proposed reporting standard for spinal cord injury experiments. J Neurotrauma (2014) 1.05
Bioinformatic analysis of neural stem cell differentiation. J Biomol Tech (2007) 1.00
Differentiating human multipotent mesenchymal stromal cells regulate microRNAs: prediction of microRNA regulation by PDGF during osteogenesis. Exp Hematol (2008) 1.00
A mouse model of ischemic spinal cord injury with delayed paralysis caused by aortic cross-clamping. Anesthesiology (2010) 1.00
Macrophage migration inhibitory factor potentiates autoimmune-mediated neuroinflammation. J Immunol (2013) 1.00
Macrophage depletion alters the blood-nerve barrier without affecting Schwann cell function after neural injury. J Neurosci Res (2007) 0.98
Central nervous system and non-central nervous system antigen vaccines exacerbate neuropathology caused by nerve injury. Eur J Neurosci (2007) 0.98
Anxiety after cardiac arrest/cardiopulmonary resuscitation: exacerbated by stress and prevented by minocycline. Stroke (2009) 0.97
Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response. J Neuroinflammation (2010) 0.97
Achieving CNS axon regeneration by manipulating convergent neuro-immune signaling. Cell Tissue Res (2012) 0.95
Ferritin stimulates oligodendrocyte genesis in the adult spinal cord and can be transferred from macrophages to NG2 cells in vivo. J Neurosci (2012) 0.94
Toll-like receptors in spinal cord injury. Curr Top Microbiol Immunol (2009) 0.93
Mediators of ischemic preconditioning identified by microarray analysis of rat spinal cord. Exp Neurol (2004) 0.93
Effects of gabapentin on muscle spasticity and both induced as well as spontaneous autonomic dysreflexia after complete spinal cord injury. Front Physiol (2012) 0.90
p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury. J Neurosci (2012) 0.90
System x(c)(-) regulates microglia and macrophage glutamate excitotoxicity in vivo. Exp Neurol (2011) 0.90
Development of a database for translational spinal cord injury research. J Neurotrauma (2014) 0.90
miR-886-3p levels are elevated in Friedreich ataxia. J Neurosci (2012) 0.89
Debate: "is increasing neuroinflammation beneficial for neural repair?". J Neuroimmune Pharmacol (2006) 0.89
Emerging concepts in myeloid cell biology after spinal cord injury. Neurotherapeutics (2011) 0.89
Secretory leukocyte protease inhibitor reverses inhibition by CNS myelin, promotes regeneration in the optic nerve, and suppresses expression of the transforming growth factor-β signaling protein Smad2. J Neurosci (2013) 0.89
Spinal cord injury therapies in humans: an overview of current clinical trials and their potential effects on intrinsic CNS macrophages. Expert Opin Ther Targets (2011) 0.89
Mutated in colorectal cancer (MCC) is a novel oncogene in B lymphocytes. J Hematol Oncol (2014) 0.88
Efficient, high-throughput transfection of human embryonic stem cells. Stem Cell Res Ther (2010) 0.87
Macrophage migration inhibitory factor (MIF) is essential for inflammatory and neuropathic pain and enhances pain in response to stress. Exp Neurol (2012) 0.86
Microtubules are critical for radial glial morphology: possible regulation by MAPs and MARKs. Glia (2003) 0.86
Spinal cord injury with unilateral versus bilateral primary hemorrhage--effects of glibenclamide. Exp Neurol (2011) 0.86
Role of induced hypothermia in thoracoabdominal aortic aneurysm surgery. Ther Hypothermia Temp Manag (2012) 0.86
Rapid induction of genes associated with tissue protection and neural development in contused adult spinal cord after radial glial cell transplantation. J Neurotrauma (2009) 0.85
Comparison of microarray and quantitative real-time PCR methods for measuring MicroRNA levels in MSC cultures. Methods Mol Biol (2011) 0.85
Methylene blue attenuates traumatic brain injury-associated neuroinflammation and acute depressive-like behavior in mice. J Neurotrauma (2014) 0.85
Biomaterial design considerations for repairing the injured spinal cord. Crit Rev Biomed Eng (2011) 0.84
Spinal cord injury causes chronic liver pathology in rats. J Neurotrauma (2014) 0.83
Activated Notch1 maintains the phenotype of radial glial cells and promotes their adhesion to laminin by upregulating nidogen. Glia (2008) 0.82
Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish. Eur J Neurosci (2012) 0.82
Characterization of spinal HSP72 induction and development of ischemic tolerance after spinal ischemia in rats. Exp Neurol (2004) 0.82
miRNA in pluripotent stem cells. Regen Med (2010) 0.82
Tissue inhibitor of metalloproteinases-1 stimulates gene expression in MDA-MB-435 human breast cancer cells by means of its ability to inhibit metalloproteinases. Breast Cancer Res Treat (2005) 0.82
Functional differentiation of a clone resembling embryonic cortical interneuron progenitors. Dev Neurobiol (2008) 0.82
Glutamate dehydrogenase 1 and SIRT4 regulate glial development. Glia (2012) 0.80
SCI-Base: an open-source spinal cord injury animal experimentation database. Lab Anim (NY) (2004) 0.79
Screening anti-inflammatory compounds in injured spinal cord with microarrays: a comparison of bioinformatics analysis approaches. Physiol Genomics (2004) 0.79
Isolation of a novel rat neural progenitor clone that expresses Dlx family transcription factors and gives rise to functional GABAergic neurons in culture. Dev Neurobiol (2012) 0.78
A high-resolution molecular-based panel of assays for identification and characterization of human embryonic stem cell lines. Stem Cell Res (2009) 0.78
Epigenome analysis of pluripotent stem cells. Methods Mol Biol (2013) 0.75