|
1
|
Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1.
|
Nucleic Acids Res
|
2007
|
1.67
|
|
2
|
The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells.
|
Mol Cancer Ther
|
2002
|
1.63
|
|
3
|
Long term low-dose arsenic exposure induces loss of DNA methylation.
|
Biochem Biophys Res Commun
|
2006
|
1.59
|
|
4
|
Aryl hydrocarbon receptor, cell cycle regulation, toxicity, and tumorigenesis.
|
J Cell Biochem
|
2005
|
1.59
|
|
5
|
Effects of arsenic exposure on DNA methylation and epigenetic gene regulation.
|
Epigenomics
|
2010
|
1.56
|
|
6
|
Expression of genes in the TGF-beta signaling pathway is significantly deregulated in smooth muscle cells from aorta of aryl hydrocarbon receptor knockout mice.
|
Toxicol Appl Pharmacol
|
2004
|
1.37
|
|
7
|
The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis.
|
Cancer Res
|
2009
|
1.37
|
|
8
|
The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phase-specific gene expression.
|
J Biol Chem
|
2004
|
1.33
|
|
9
|
Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation.
|
Mol Cell Biol
|
2007
|
1.31
|
|
10
|
Ligand-independent regulation of transforming growth factor beta1 expression and cell cycle progression by the aryl hydrocarbon receptor.
|
Mol Cell Biol
|
2007
|
1.30
|
|
11
|
Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status.
|
Toxicol Sci
|
2005
|
1.29
|
|
12
|
HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation associated with Ah receptor-mediated trans-activation.
|
Biochim Biophys Acta
|
2007
|
1.27
|
|
13
|
Mitochondrial reactive oxygen production is dependent on the aromatic hydrocarbon receptor.
|
Free Radic Biol Med
|
2002
|
1.24
|
|
14
|
Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs.
|
Environ Health Perspect
|
2009
|
1.22
|
|
15
|
The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis.
|
Mol Biol Cell
|
2008
|
1.21
|
|
16
|
Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function.
|
Biochem Pharmacol
|
2002
|
1.17
|
|
17
|
Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin.
|
J Biol Chem
|
2003
|
1.10
|
|
18
|
Different global gene expression profiles in benzo[a]pyrene- and dioxin-treated vascular smooth muscle cells of AHR-knockout and wild-type mice.
|
Cardiovasc Toxicol
|
2004
|
1.08
|
|
19
|
Gene expression profiling reveals novel regulation by bisphenol-A in estrogen receptor-alpha-positive human cells.
|
Environ Res
|
2005
|
1.05
|
|
20
|
Arsenic co-exposure potentiates benzo[a]pyrene genotoxicity.
|
Mutat Res
|
2002
|
1.04
|
|
21
|
Induction of cellular oxidative stress by aryl hydrocarbon receptor activation.
|
Chem Biol Interact
|
2002
|
1.03
|
|
22
|
2,3,7,8-Tetrachlorodibenzo-p-dioxin blocks androgen-dependent cell proliferation of LNCaP cells through modulation of pRB phosphorylation.
|
Mol Pharmacol
|
2004
|
1.01
|
|
23
|
Fitting a xenobiotic receptor into cell homeostasis: how the dioxin receptor interacts with TGFbeta signaling.
|
Biochem Pharmacol
|
2008
|
1.01
|
|
24
|
A critical role for MAP kinases in the control of Ah receptor complex activity.
|
Toxicol Sci
|
2004
|
0.98
|
|
25
|
BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite.
|
J Biol Chem
|
2008
|
0.97
|
|
26
|
Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis.
|
Environ Health Perspect
|
2013
|
0.97
|
|
27
|
Recruitment of CREB1 and histone deacetylase 2 (HDAC2) to the mouse Ltbp-1 promoter regulates its constitutive expression in a dioxin receptor-dependent manner.
|
J Mol Biol
|
2008
|
0.95
|
|
28
|
Aryl hydrocarbon receptor ligands of widely different toxic equivalency factors induce similar histone marks in target gene chromatin.
|
Toxicol Sci
|
2011
|
0.94
|
|
29
|
Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closure.
|
Proc Natl Acad Sci U S A
|
2011
|
0.94
|
|
30
|
Distinct contributions of JNK and p38 to chromium cytotoxicity and inhibition of murine embryonic stem cell differentiation.
|
Environ Health Perspect
|
2009
|
0.92
|
|
31
|
Inhibitor of kappaB kinase beta regulates redox homeostasis by controlling the constitutive levels of glutathione.
|
Mol Pharmacol
|
2010
|
0.90
|
|
32
|
Bisphenol-A and estradiol exert novel gene regulation in human MCF-7 derived breast cancer cells.
|
Mol Cell Endocrinol
|
2004
|
0.89
|
|
33
|
The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways.
|
EXS
|
2009
|
0.88
|
|
34
|
Arsenite-induced aryl hydrocarbon receptor nuclear translocation results in additive induction of phase I genes and synergistic induction of phase II genes.
|
Mol Pharmacol
|
2005
|
0.86
|
|
35
|
Repression of Ah receptor and induction of transforming growth factor-beta genes in DEN-induced mouse liver tumors.
|
Toxicology
|
2008
|
0.85
|
|
36
|
Dioxin exposure disrupts the differentiation of mouse embryonic stem cells into cardiomyocytes.
|
Toxicol Sci
|
2010
|
0.85
|
|
37
|
Induction of oxidative stress responses by dioxin and other ligands of the aryl hydrocarbon receptor.
|
Dose Response
|
2006
|
0.84
|
|
38
|
Biological functions of the arylhydrocarbon receptor: beyond induction of cytochrome P450s. Introduction to this special issue.
|
Biochem Pharmacol
|
2008
|
0.81
|
|
39
|
Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs.
|
Biochem Biophys Res Commun
|
2006
|
0.81
|
|
40
|
Retention of Cr(III) by high-performance chelation ion chromatography interfaced to inductively-coupled plasma mass spectrometric detection with collision cell.
|
J Chromatogr A
|
2004
|
0.80
|
|
41
|
Covalent binding of quinones activates the Ah receptor in Hepa1c1c7 cells.
|
J Toxicol Sci
|
2015
|
0.79
|
|
42
|
Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies.
|
Toxicol Lett
|
2005
|
0.79
|
|
43
|
Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood.
|
Environ Health Perspect
|
2015
|
0.79
|
|
44
|
Lead induces similar gene expression changes in brains of gestationally exposed adult mice and in neurons differentiated from mouse embryonic stem cells.
|
PLoS One
|
2013
|
0.79
|
|
45
|
Distinct signaling properties of mitogen-activated protein kinase kinases 4 (MKK4) and 7 (MKK7) in embryonic stem cell (ESC) differentiation.
|
J Biol Chem
|
2011
|
0.78
|
|
46
|
The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.
|
Toxicol Sci
|
2014
|
0.78
|
|
47
|
Long-term exposure to hexavalent chromium inhibits expression of tumor suppressor genes in cultured cells and in mice.
|
J Trace Elem Med Biol
|
2012
|
0.78
|
|
48
|
Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator.
|
J Toxicol Sci
|
2016
|
0.75
|