Published in Diabetes on August 01, 2005
AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J Physiol (2006) 2.06
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A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol (2005) 3.98
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Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes. Cell Metab (2005) 3.51
Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake. Cell Metab (2007) 3.43
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Regulation of pancreatic beta cell mass by neuronal signals from the liver. Science (2008) 2.74
Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron (2005) 2.66
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The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev (2005) 2.18
Adiponectin protects LPS-induced liver injury through modulation of TNF-alpha in KK-Ay obese mice. Hepatology (2004) 2.18
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Novel adipose tissue-mediated resistance to diet-induced visceral obesity in 11 beta-hydroxysteroid dehydrogenase type 1-deficient mice. Diabetes (2004) 2.12
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Incremental effects of eicosapentaenoic acid on cardiovascular events in statin-treated patients with coronary artery disease. Circ J (2009) 2.01
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Impaired CNS leptin action is implicated in depression associated with obesity. Endocrinology (2011) 1.92
NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. EMBO J (2003) 1.87
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Urinary neutrophil gelatinase-associated lipocalin levels reflect damage to glomeruli, proximal tubules, and distal nephrons. Kidney Int (2008) 1.85
Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metab (2005) 1.83
Disruption of CXC motif chemokine ligand-14 in mice ameliorates obesity-induced insulin resistance. J Biol Chem (2007) 1.75
Role of Rho-kinase in regulation of insulin action and glucose homeostasis. Cell Metab (2005) 1.73
Reduction in connective tissue growth factor by antisense treatment ameliorates renal tubulointerstitial fibrosis. J Am Soc Nephrol (2004) 1.70
Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy. J Clin Endocrinol Metab (2006) 1.68
Relevant use of Klotho in FGF19 subfamily signaling system in vivo. Proc Natl Acad Sci U S A (2010) 1.66
A liver-derived secretory protein, selenoprotein P, causes insulin resistance. Cell Metab (2010) 1.63
Pathway for differentiation of human embryonic stem cells to vascular cell components and their potential for vascular regeneration. Arterioscler Thromb Vasc Biol (2007) 1.63
Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation. Biochem Biophys Res Commun (2007) 1.63
Leptin stimulates fatty acid oxidation and peroxisome proliferator-activated receptor alpha gene expression in mouse C2C12 myoblasts by changing the subcellular localization of the alpha2 form of AMP-activated protein kinase. Mol Cell Biol (2007) 1.62
Angiopoietin-related growth factor antagonizes obesity and insulin resistance. Nat Med (2005) 1.61
The role of mineralocorticoid receptor expression in brain remodeling after cerebral ischemia. Endocrinology (2008) 1.61
Increased adiponectin secretion by highly purified eicosapentaenoic acid in rodent models of obesity and human obese subjects. Arterioscler Thromb Vasc Biol (2007) 1.60
Highly purified eicosapentaenoic acid reduces cardio-ankle vascular index in association with decreased serum amyloid A-LDL in metabolic syndrome. Hypertens Res (2009) 1.58
Intraoperative radiotherapy for resected pancreatic cancer: a multi-institutional retrospective analysis of 210 patients. Int J Radiat Oncol Biol Phys (2010) 1.58
TBC1D1 regulates insulin- and contraction-induced glucose transport in mouse skeletal muscle. Diabetes (2010) 1.55
Effects of candesartan compared with amlodipine in hypertensive patients with high cardiovascular risks: candesartan antihypertensive survival evaluation in Japan trial. Hypertension (2008) 1.54
Combined dominant frequency and complex fractionated atrial electrogram ablation after circumferential pulmonary vein isolation of atrial fibrillation. J Cardiovasc Electrophysiol (2013) 1.54
Attenuation of diet-induced weight gain and adiposity through increased energy expenditure in mice lacking angiotensin II type 1a receptor. Endocrinology (2005) 1.54
Role of natriuretic peptide receptor guanylyl cyclase-A in myocardial infarction evaluated using genetically engineered mice. Hypertension (2005) 1.53
An increase in murine skeletal muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) mRNA in response to exercise is mediated by beta-adrenergic receptor activation. Endocrinology (2007) 1.52
Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells. Atherosclerosis (2010) 1.52
Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system. Cell Metab (2009) 1.51
Dysregulation of adipose glutathione peroxidase 3 in obesity contributes to local and systemic oxidative stress. Mol Endocrinol (2008) 1.51
CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass. J Atheroscler Thromb (2015) 1.50
TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-1c (SREBP-1c). Exp Biol Med (Maywood) (2007) 1.50
Thrombin-activatable fibrinolysis inhibitor and protein C inhibitor in interstitial lung disease. Am J Respir Crit Care Med (2003) 1.49
The effect of glycosylation on plasma N-terminal proBNP-76 levels in patients with heart or renal failure. Heart (2011) 1.48
Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle. Proc Natl Acad Sci U S A (2010) 1.48
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Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway. Nat Med (2004) 1.48
Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue. J Biol Chem (2008) 1.48
Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. J Am Soc Nephrol (2005) 1.47
GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization. J Clin Invest (2004) 1.47
Gender difference in baroreflex sensitivity to predict cardiac and cerebrovascular events in type 2 diabetic patients. Circ J (2011) 1.47
Significance and therapeutic potential of the natriuretic peptides/cGMP/cGMP-dependent protein kinase pathway in vascular regeneration. Proc Natl Acad Sci U S A (2003) 1.46
Histidine suppresses food intake through its conversion into neuronal histamine. Exp Biol Med (Maywood) (2002) 1.45
Chronic central leptin infusion restores hyperglycemia independent of food intake and insulin level in streptozotocin-induced diabetic rats. FASEB J (2002) 1.44
High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet (2007) 1.44
Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett (2009) 1.43
A phase II study on stereotactic body radiotherapy for stage I non-small cell lung cancer. Radiother Oncol (2007) 1.43
Central control of fever and female body temperature by RANKL/RANK. Nature (2009) 1.42
Induction and isolation of vascular cells from human induced pluripotent stem cells--brief report. Arterioscler Thromb Vasc Biol (2009) 1.42
Transesophageal echocardiography for thrombus screening prior to left atrial catheter ablation. Circ J (2010) 1.42
Engineered interface of magnetic oxides. Science (2004) 1.42