Published in Cell on June 12, 1992
An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics (1999) 5.87
The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J Cell Biol (1995) 2.69
Developmental regulation of transcription by a tissue-specific TAF homolog. Genes Dev (2001) 1.92
The Arabidopsis SKP1-LIKE1 gene is essential for male meiosis and may control homologue separation. Proc Natl Acad Sci U S A (1999) 1.80
A gain-of-function screen for genes that affect the development of the Drosophila adult external sensory organ. Genetics (2000) 1.52
Pyp3 PTPase acts as a mitotic inducer in fission yeast. EMBO J (1992) 1.50
Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion. Proc Natl Acad Sci U S A (2009) 1.37
Yeast dom34 mutants are defective in multiple developmental pathways and exhibit decreased levels of polyribosomes. Genetics (1998) 1.35
Requirements for dE2F function in proliferating cells and in post-mitotic differentiating cells. EMBO J (1996) 1.33
Isolation of Drosophila cyclin D, a protein expressed in the morphogenetic furrow before entry into S phase. Proc Natl Acad Sci U S A (1996) 1.30
Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitro. Mol Biol Cell (1995) 1.24
Identification of transcriptional targets of the dual-function transcription factor/phosphatase eyes absent. Dev Biol (2007) 1.23
Mechanism and regulation of Cdc25/Twine protein destruction in embryonic cell-cycle remodeling. Curr Biol (2013) 1.23
Meiosis in Drosophila: seeing is believing. Proc Natl Acad Sci U S A (1995) 1.21
Drosophila wee1 has an essential role in the nuclear divisions of early embryogenesis. Genetics (2000) 1.20
alpha-Endosulfine is a conserved protein required for oocyte meiotic maturation in Drosophila. Development (2008) 1.17
Embryonic onset of late replication requires Cdc25 down-regulation. Genes Dev (2012) 1.17
Regulation of maternal transcript destabilization during egg activation in Drosophila. Genetics (2003) 1.16
Determination of gene expression patterns using in situ hybridization to Drosophila testes. Nat Protoc (2009) 1.09
Developmental control of oocyte maturation and egg activation in metazoan models. Cold Spring Harb Perspect Biol (2011) 1.09
Translational control of meiotic cell cycle progression and spermatid differentiation in male germ cells by a novel eIF4G homolog. Development (2007) 1.08
The overlooked greatwall: a new perspective on mitotic control. Open Biol (2012) 1.08
Nuclear localization and cell cycle regulation of a murine protein tyrosine phosphatase. Mol Cell Biol (1994) 1.07
KLP38B: a mitotic kinesin-related protein that binds PP1. J Cell Biol (1997) 1.07
A novel requirement in mammalian spermatid differentiation for the DAZ-family protein Boule. Hum Mol Genet (2010) 1.06
In vivo roles of CDC25 phosphatases: biological insight into the anti-cancer therapeutic targets. Anticancer Agents Med Chem (2008) 1.06
Identification of genomic regions required for DNA replication during Drosophila embryogenesis. Genetics (1993) 1.05
Asunder is a critical regulator of dynein-dynactin localization during Drosophila spermatogenesis. Mol Biol Cell (2009) 0.94
From egg to gastrula: how the cell cycle is remodeled during the Drosophila mid-blastula transition. Annu Rev Genet (2014) 0.94
The roles of the DAZ family in spermatogenesis: More than just translation? Spermatogenesis (2011) 0.92
Genetic and developmental characterization of Dmca1D, a calcium channel alpha1 subunit gene in Drosophila melanogaster. Genetics (1998) 0.92
String (Cdc25) regulates stem cell maintenance, proliferation and aging in Drosophila testis. Development (2011) 0.92
Transcriptional regulation by Modulo integrates meiosis and spermatid differentiation in male germ line. Proc Natl Acad Sci U S A (2006) 0.92
glp-3 is required for mitosis and meiosis in the Caenorhabditis elegans germ line. Genetics (1997) 0.89
Unique aspects of transcription regulation in male germ cells. Cold Spring Harb Perspect Biol (2011) 0.88
Spitz from the retina regulates genes transcribed in the second mitotic wave, peripodial epithelium, glia and plasmatocytes of the Drosophila eye imaginal disc. Dev Biol (2007) 0.87
Boule-like genes regulate male and female gametogenesis in the flatworm Macrostomum lignano. Dev Biol (2011) 0.85
The CPEB protein Orb2 has multiple functions during spermatogenesis in Drosophila melanogaster. PLoS Genet (2012) 0.83
The polyubiquitin gene Ubi-p63E is essential for male meiotic cell cycle progression and germ cell differentiation in Drosophila. Development (2013) 0.83
A novel predicted bromodomain-related protein affects coordination between meiosis and spermiogenesis in Drosophila and is required for male meiotic cytokinesis. DNA Cell Biol (2010) 0.81
Molecular characterization of teflon, a gene required for meiotic autosome segregation in male Drosophila melanogaster. Genetics (2006) 0.80
CDC-25.2, a C. elegans ortholog of cdc25, is essential for the progression of intestinal divisions. Cell Cycle (2016) 0.79
Cell type-specific translational repression of Cyclin B during meiosis in males. Development (2015) 0.79
Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. PLoS One (2015) 0.78
Molecular cloning and characterization of a novel dual-specificity protein phosphatase possibly involved in spermatogenesis. Biochem J (1999) 0.78
Transcriptional regulation during Drosophila spermatogenesis. Spermatogenesis (2012) 0.78
The analysis of mutant alleles of different strength reveals multiple functions of topoisomerase 2 in regulation of Drosophila chromosome structure. PLoS Genet (2014) 0.77
Waves of Cdk1 Activity in S Phase Synchronize the Cell Cycle in Drosophila Embryos. Dev Cell (2016) 0.76
Insights into molecular features of Venerupis decussata oocytes: a microarray-based study. PLoS One (2014) 0.76
Inventory and phylogenetic analysis of meiotic genes in monogonont rotifers. J Hered (2013) 0.76
Carboxy-terminal phosphorylation sites in Cdc25 contribute to enforcement of the DNA damage and replication checkpoints in fission yeast. Curr Genet (2012) 0.76
Myt1 inhibition of Cyclin A/Cdk1 is essential for fusome integrity and premeiotic centriole engagement in Drosophila spermatocytes. Mol Biol Cell (2016) 0.76
Autosomal mutations affecting Y chromosome loops in Drosophila melanogaster. BMC Genet (2008) 0.75
Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol (1991) 33.90
Characterization of six cloned DNAs from Drosophila melanogaster, including one that contains the genes for rRNA. Cell (1975) 15.07
The genome sequence of Schizosaccharomyces pombe. Nature (2002) 14.26
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature (1989) 11.90
Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet (1976) 9.64
Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature (1987) 8.87
cdc25+ functions as an inducer in the mitotic control of fission yeast. Cell (1986) 8.82
Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog. Cell (1987) 8.76
Genetic control of cell size at cell division in yeast. Nature (1975) 7.74
Animal cell cycles and their control. Annu Rev Biochem (1992) 6.60
Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+. Cell (1988) 6.29
The fission yeast cdc18+ gene product couples S phase to START and mitosis. Cell (1993) 6.25
Gene required in G1 for commitment to cell cycle and in G2 for control of mitosis in fission yeast. Nature (1981) 5.98
Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell (1990) 5.42
Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis. J Cell Biol (2001) 5.34
Regulation of p34cdc2 protein kinase during mitosis. Cell (1989) 5.33
Construction of a Schizosaccharomyces pombe gene bank in a yeast bacterial shuttle vector and its use to isolate genes by complementation. Mol Gen Genet (1982) 5.17
polo, a mitotic mutant of Drosophila displaying abnormal spindle poles. J Cell Sci (1988) 4.77
The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation. Cell (1986) 4.73
Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev (1992) 4.62
Intestinal Obstruction in the Newborn. Ann Surg (1949) 4.61
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis. Nature (1991) 4.60
Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function. EMBO J (1991) 4.59
SAK/PLK4 is required for centriole duplication and flagella development. Curr Biol (2005) 4.52
The Cdt1 protein is required to license DNA for replication in fission yeast. Nature (2000) 4.46
Substrates for p34cdc2: in vivo veritas? Cell (1990) 4.34
Control of cell size at division in fission yeast by a growth-modulated size control over nuclear division. Exp Cell Res (1977) 4.31
Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. EMBO J (1991) 4.04
A novel arrangement of the 18S and 28S sequences in a repeating unit of Drosophila melanogaster rDNA. Cell (1977) 3.99
Growth in cell length in the fission yeast Schizosaccharomyces pombe. J Cell Sci (1985) 3.99
pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis. Genes Dev (1998) 3.88
Cell division cycle mutants altered in DNA replication and mitosis in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet (1981) 3.87
Cloning, sequencing and transcriptional control of the Schizosaccharomyces pombe cdc10 'start' gene. EMBO J (1985) 3.87
The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis. Cell (1987) 3.82
polo encodes a protein kinase homolog required for mitosis in Drosophila. Genes Dev (1991) 3.81
Functionally homologous cell cycle control genes in budding and fission yeast. Nature (1982) 3.78
p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase. EMBO J (1989) 3.70
Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene. Nature (1994) 3.56
Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex. Cell (1994) 3.52
The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells. Genes Dev (1995) 3.52
cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. J Cell Biol (1997) 3.46
Regulatory genes controlling mitosis in the fission yeast Schizosaccharomyces pombe. Genetics (1980) 3.42
Genome-wide survey of protein kinases required for cell cycle progression. Nature (2004) 3.40
Chromatid segregation at anaphase requires the barren product, a novel chromosome-associated protein that interacts with Topoisomerase II. Cell (1996) 3.39
Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. EMBO J (1997) 3.38
Cohesin Rec8 is required for reductional chromosome segregation at meiosis. Nature (1999) 3.35
p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast. Cell (1995) 3.29
CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast. Cell (2000) 3.21
tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell. Cell (1997) 3.15
Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe. Annu Rev Cell Biol (1991) 3.14
Dephosphorylation and activation of Xenopus p34cdc2 protein kinase during the cell cycle. Nature (1989) 3.12
Purification of MPF from starfish: identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation. Cell (1989) 3.05
Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring. J Cell Sci (1996) 3.01
The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition. EMBO J (1990) 2.99
Cloning and sequencing of the cyclin-related cdc13+ gene and a cytological study of its role in fission yeast mitosis. J Cell Sci (1988) 2.96
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination. Nature (1998) 2.95
One of the protein phosphatase 1 isoenzymes in Drosophila is essential for mitosis. Cell (1990) 2.91
Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein. Nature (1988) 2.88
Regulation of mitosis by cyclic accumulation of p80cdc25 mitotic inducer in fission yeast. Nature (1990) 2.86
A cdc2-like protein is involved in the initiation of DNA replication in Xenopus egg extracts. Cell (1990) 2.84
Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells. Mol Cell Biol (1989) 2.75
Fission yeast Schizosaccharomyces pombe correctly excises a mammalian RNA transcript intervening sequence. Nature (1985) 2.74
Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat. Neuroscience (2008) 2.74
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product. Cell (1990) 2.73
Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity. Oncogene (2008) 2.72
Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+. Nature (1988) 2.71
Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase. Science (1990) 2.63
Revisiting the role of the mother centriole in centriole biogenesis. Science (2007) 2.59
Vectors for the construction of gene banks and the integration of cloned genes in Schizosaccharomyces pombe and Saccharomyces cerevisiae. Plasmid (1986) 2.58
A single fission yeast mitotic cyclin B p34cdc2 kinase promotes both S-phase and mitosis in the absence of G1 cyclins. EMBO J (1996) 2.58
A small peptide inhibitor of DNA replication defines the site of interaction between the cyclin-dependent kinase inhibitor p21WAF1 and proliferating cell nuclear antigen. Curr Biol (1995) 2.57
A quantitative model for the cdc2 control of S phase and mitosis in fission yeast. Trends Genet (1996) 2.54
Arrangements and rearrangements of sequences flanking the two types of rDNA insertion in D. melanogaster. Nature (1981) 2.50
Somatic support cells restrict germline stem cell self-renewal and promote differentiation. Nature (2000) 2.48
p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase. Cell (1995) 2.48
Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication. Cell (1991) 2.47
The fission yeast cell cycle control gene cdc2: isolation of a sequence suc1 that suppresses cdc2 mutant function. Mol Gen Genet (1986) 2.46
Expression of the SV40 promoter in fission yeast: identification and characterization of an AP-1-like factor. Cell (1988) 2.44
PCR amplification of DNA microdissected from a single polytene chromosome band: a comparison with conventional microcloning. Nucleic Acids Res (1989) 2.43
Drosophila polo kinase is required for cytokinesis. J Cell Biol (1998) 2.30
Periodic transcription as a means of regulating gene expression during the cell cycle: contrasting modes of expression of DNA ligase genes in budding and fission yeast. EMBO J (1986) 2.29
Controls over the timing of DNA replication during the cell cycle of fission yeast. Exp Cell Res (1977) 2.27
Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle. J Cell Biol (1995) 2.26
The 55 kd regulatory subunit of Drosophila protein phosphatase 2A is required for anaphase. Cell (1993) 2.26
Abnormal spindle protein, Asp, and the integrity of mitotic centrosomal microtubule organizing centers. Science (1999) 2.23
Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle. Proc Natl Acad Sci U S A (1998) 2.20
A fission yeast RCC1-related protein is required for the mitosis to interphase transition. EMBO J (1994) 2.15
P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: correlation of physical and cytogenetic maps in chromosomal region 86E-87F. Genetics (1997) 2.14
Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res (2013) 2.12
cut11(+): A gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and bipolar spindle formation in Schizosaccharomyces pombe. Mol Biol Cell (1998) 2.11
Uncontrolled septation in a cell division cycle mutant of the fission yeast Schizosaccharomyces pombe. J Bacteriol (1979) 2.06
mini spindles: A gene encoding a conserved microtubule-associated protein required for the integrity of the mitotic spindle in Drosophila. J Cell Biol (1999) 2.06
Schizosaccharomyces pombe and Saccharomyces cerevisiae: a look at yeasts divided. Cell (1986) 2.06
Antibiotic prescription for community-acquired pneumonia in the intensive care unit: impact of adherence to Infectious Diseases Society of America guidelines on survival. Clin Infect Dis (2005) 2.05
Mutants altered in the control co-ordinating cell division with cell growth in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet (1978) 2.03
Molecular cloning and sequence analysis of mutant alleles of the fission yeast cdc2 protein kinase gene: implications for cdc2+ protein structure and function. Mol Gen Genet (1989) 2.02
suc1 is an essential gene involved in both the cell cycle and growth in fission yeast. EMBO J (1986) 1.99
The Drosophila gene abnormal spindle encodes a novel microtubule-associated protein that associates with the polar regions of the mitotic spindle. J Cell Biol (1997) 1.98
Transcription of the 'non-transcribed' spacer of Drosophila melanogaster rDNA. Nucleic Acids Res (1983) 1.88