Published in Am J Med Genet A on September 15, 2005
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature (2011) 5.45
The branching programme of mouse lung development. Nature (2008) 4.73
The genome of the Western clawed frog Xenopus tropicalis. Science (2010) 4.70
The dynamic genome of Hydra. Nature (2010) 4.00
Mutations in the gene encoding filamin B disrupt vertebral segmentation, joint formation and skeletogenesis. Nat Genet (2004) 2.94
Endocrine disrupters as obesogens. Mol Cell Endocrinol (2009) 2.80
Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling. Endocrinology (2006) 2.56
Endocrine-disrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Mol Endocrinol (2006) 2.41
Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. J Clin Invest (2006) 2.28
Endocrine disrupting chemicals and disease susceptibility. J Steroid Biochem Mol Biol (2011) 2.28
Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia. Nat Genet (2008) 2.24
Highly chlorinated PCBs inhibit the human xenobiotic response mediated by the steroid and xenobiotic receptor (SXR). Environ Health Perspect (2004) 2.16
A genome-wide association study identifies susceptibility loci for nonsyndromic sagittal craniosynostosis near BMP2 and within BBS9. Nat Genet (2012) 2.12
Transgenerational inheritance of increased fat depot size, stem cell reprogramming, and hepatic steatosis elicited by prenatal exposure to the obesogen tributyltin in mice. Environ Health Perspect (2013) 2.12
Mutations in the gene encoding the calcium-permeable ion channel TRPV4 produce spondylometaphyseal dysplasia, Kozlowski type and metatropic dysplasia. Am J Hum Genet (2009) 2.02
Clinical features and management issues in Mowat-Wilson syndrome. Am J Med Genet A (2006) 1.97
Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis. Rev Endocr Metab Disord (2007) 1.96
Evaluation of prenatal-onset osteochondrodysplasias by ultrasonography: a retrospective and prospective analysis. Am J Med Genet A (2008) 1.91
Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes. Mol Endocrinol (2010) 1.84
Lgr5-expressing cells are sufficient and necessary for postnatal mammary gland organogenesis. Cell Rep (2013) 1.78
Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. J Clin Invest (2006) 1.75
Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem (2003) 1.69
Predicting later-life outcomes of early-life exposures. Environ Health Perspect (2012) 1.67
Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ). Environ Health Perspect (2012) 1.63
Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors. Dev Cell (2012) 1.57
Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development (2010) 1.55
New modes of action for endocrine-disrupting chemicals. Mol Endocrinol (2005) 1.54
Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity. Birth Defects Res C Embryo Today (2011) 1.52
The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor. Mol Pharmacol (2006) 1.47
Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning. Development (2010) 1.43
Science and policy on endocrine disrupters must not be mixed: a reply to a "common sense" intervention by toxicology journal editors. Environ Health (2013) 1.42
The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. Nucl Recept Signal (2009) 1.41
Minireview: PPARγ as the target of obesogens. J Steroid Biochem Mol Biol (2011) 1.40
A molecular and clinical study of Larsen syndrome caused by mutations in FLNB. J Med Genet (2006) 1.34
Minireview: the case for obesogens. Mol Endocrinol (2009) 1.33
Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem (2006) 1.33
Learning from and about others: towards using imitation to bootstrap the social understanding of others by robots. Artif Life (2005) 1.28
BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. Nat Cell Biol (2013) 1.26
Expression of the steroid and xenobiotic receptor and its possible target gene, organic anion transporting polypeptide-A, in human breast carcinoma. Cancer Res (2006) 1.26
The obesogenic effect of high fructose exposure during early development. Nat Rev Endocrinol (2013) 1.23
A recessive skeletal dysplasia, SEMD aggrecan type, results from a missense mutation affecting the C-type lectin domain of aggrecan. Am J Hum Genet (2008) 1.17
The environmental obesogen tributyltin chloride acts via peroxisome proliferator activated receptor gamma to induce adipogenesis in murine 3T3-L1 preadipocytes. J Steroid Biochem Mol Biol (2011) 1.17
Steroid and xenobiotic receptor (SXR), cytochrome P450 3A4 and multidrug resistance gene 1 in human adult and fetal tissues. Mol Cell Endocrinol (2005) 1.15
Broad phenotypic spectrum caused by an identical heterozygous CDMP-1 mutation in three unrelated families. Am J Med Genet A (2003) 1.15
Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors. J Biol Chem (2002) 1.11
Marked phenotypic variability in progressive diaphyseal dysplasia (Camurati-Engelmann disease): report of a four-generation pedigree, identification of a mutation in TGFB1, and review. Am J Med Genet A (2004) 1.10
Angulated femurs and the skeletal dysplasias: experience of the International Skeletal Dysplasia Registry (1988-2006). Am J Med Genet A (2007) 1.09
Tocotrienols activate the steroid and xenobiotic receptor, SXR, and selectively regulate expression of its target genes. Drug Metab Dispos (2004) 1.09
Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. Development (2011) 1.08
Active repression by unliganded retinoid receptors in development: less is sometimes more. J Cell Biol (2003) 1.08
Bisphenol A diglycidyl ether induces adipogenic differentiation of multipotent stromal stem cells through a peroxisome proliferator-activated receptor gamma-independent mechanism. Environ Health Perspect (2012) 1.07
Exome sequencing identifies PDE4D mutations in acrodysostosis. Am J Hum Genet (2012) 1.07
Mutations in two regions of FLNB result in atelosteogenesis I and III. Hum Mutat (2006) 1.06
Guidelines for the prenatal diagnosis of fetal skeletal dysplasias. Genet Med (2009) 1.06
Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors. Development (2010) 1.06
FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size. PLoS Genet (2011) 1.04
The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development (2013) 1.04
Revitalization of a diastemal tooth primordium in Spry2 null mice results from increased proliferation and decreased apoptosis. J Exp Zool B Mol Dev Evol (2009) 1.02
Characterizing genetic variants for clinical action. Am J Med Genet C Semin Med Genet (2014) 1.02
Activation of the steroid and xenobiotic receptor, SXR, induces apoptosis in breast cancer cells. BMC Cancer (2009) 1.02
A novel dysmorphic syndrome with open calvarial sutures and sutural cataracts maps to chromosome 14q13-q21. Hum Genet (2003) 1.02
Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity. Am J Hum Genet (2011) 1.02
The skeletal dysplasias: clinical-molecular correlations. Ann N Y Acad Sci (2007) 1.02
Bent bone dysplasia-FGFR2 type, a distinct skeletal disorder, has deficient canonical FGF signaling. Am J Hum Genet (2012) 1.02
The Erlenmeyer flask bone deformity in the skeletal dysplasias. Am J Med Genet A (2009) 1.00
Multiple points of interaction between retinoic acid and FGF signaling during embryonic axis formation. Development (2004) 0.99
Obesity, diabetes, and associated costs of exposure to endocrine-disrupting chemicals in the European Union. J Clin Endocrinol Metab (2015) 0.99
Expression levels and activation of a PXR variant are directly related to drug resistance in osteosarcoma cell lines. Cancer (2007) 0.96
E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor. Dev Biol (2012) 0.96
Unraveling the molecular mechanisms that lead to supernumerary teeth in mice and men: current concepts and novel approaches. Cells Tissues Organs (2007) 0.96
Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species. Environ Health Perspect (2008) 0.95
The importance of conventional radiography in the mutational analysis of skeletal dysplasias (the TRPV4 mutational family). Pediatr Radiol (2011) 0.95
The Shwachman-Bodian-Diamond syndrome gene mutations cause a neonatal form of spondylometaphysial dysplasia (SMD) resembling SMD Sedaghatian type. J Med Genet (2007) 0.94
Designing green oxidation catalysts for purifying environmental waters. J Am Chem Soc (2010) 0.93
Stem cell and biomaterials research in dental tissue engineering and regeneration. Dent Clin North Am (2012) 0.93
Injectable bone tissue engineering using expanded mesenchymal stem cells. Stem Cells (2013) 0.93
Expression of microRNAs in the stem cell niche of the adult mouse incisor. PLoS One (2011) 0.92
Distinctive phenotype in 9 patients with deletion of chromosome 1q24-q25. Am J Med Genet A (2011) 0.92
From molecules to mastication: the development and evolution of teeth. Wiley Interdiscip Rev Dev Biol (2012) 0.92
Spectrum of dolichospondylic dysplasia: two new patients with distinctive findings. Am J Med Genet (2002) 0.91
Further clinical and molecular delineation of the 15q24 microdeletion syndrome. J Med Genet (2011) 0.91
Characterization of dental epithelial stem cells from the mouse incisor with two-dimensional and three-dimensional platforms. Tissue Eng Part C Methods (2012) 0.90
Differentiating campomelic dysplasia from Cumming syndrome. Am J Med Genet A (2005) 0.89
Ossification sequence in infants who die during the perinatal period: population-based references. Radiology (2002) 0.89
Diaphanospondylodysostosis: six new cases and exclusion of the candidate genes, PAX1 and MEOX1. Am J Med Genet A (2007) 0.89
van den Ende-Gupta syndrome of blepharophimosis, arachnodactyly, and congenital contractures: clinical delineation and recurrence in brothers. Am J Med Genet A (2003) 0.89
PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci (2011) 0.89
Osteocraniostenosis-hypomineralized skull with gracile long bones and splenic hypoplasia. Four new cases with distinctive chondro-osseous morphology. Am J Med Genet A (2006) 0.88
Global analysis of RAR-responsive genes in the Xenopus neurula using cDNA microarrays. Dev Dyn (2005) 0.88
Fibroblast growth factor signaling in mammalian tooth development. Odontology (2013) 0.88
Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47. Environ Sci Technol (2014) 0.88
How do women of diverse backgrounds value prenatal testing outcomes? Prenat Diagn (2004) 0.88
Nutrition can modulate the toxicity of environmental pollutants: implications in risk assessment and human health. Environ Health Perspect (2012) 0.88
Oral epithelial stem cells in tissue maintenance and disease: the first steps in a long journey. Int J Oral Sci (2013) 0.87
Hyperforin, the active component of St. John's wort, induces IL-8 expression in human intestinal epithelial cells via a MAPK-dependent, NF-kappaB-independent pathway. J Clin Immunol (2004) 0.86
A review of the principles of radiological assessment of skeletal dysplasias. J Clin Res Pediatr Endocrinol (2011) 0.86
Van den Ende-Gupta syndrome: laryngeal abnormalities in two siblings. Am J Med Genet A (2007) 0.86
Overlapping gene structure of human VLCAD and DLG4. Gene (2003) 0.86
Sprouty genes regulate proliferation and survival of human embryonic stem cells. Sci Rep (2013) 0.86
Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic. Environ Health Perspect (2016) 0.86