Published in Nature on August 11, 2005
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet (2010) 2.33
SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet (2008) 2.19
Prospects for epigenetic epidemiology. Am J Epidemiol (2009) 2.00
FXN methylation predicts expression and clinical outcome in Friedreich ataxia. Ann Neurol (2012) 1.83
Transcription within a functional human centromere. Mol Cell (2003) 1.77
Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res (2012) 1.73
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface. J Biol Chem (2009) 1.50
Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition. Blood (2010) 1.39
Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors. BMC Genomics (2011) 1.39
Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance. Genome Biol (2013) 1.36
Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation. PLoS Genet (2006) 1.26
Communicating genetic information in families--a review of guidelines and position papers. Eur J Hum Genet (2007) 1.21
DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta. J Biol Chem (2010) 1.15
Twin registries worldwide: an important resource for scientific research. Twin Res Hum Genet (2013) 1.07
A distinct DNA methylation signature defines pediatric pre-B cell acute lymphoblastic leukemia. Epigenetics (2012) 1.04
Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function. Mol Hum Reprod (2011) 1.03
Maternal vitamin D predominates over genetic factors in determining neonatal circulating vitamin D concentrations. Am J Clin Nutr (2012) 1.03
Multimedia messages in genetics: design, development, and evaluation of a computer-based instructional resource for secondary school students in a Tay Sachs disease carrier screening program. Genet Med (2004) 1.00
A model for the development of genetics education programs for health professionals. Genet Med (2007) 0.98
The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation. Atherosclerosis (2013) 0.91
'It is not in my world': an exploration of attitudes and influences associated with cystic fibrosis carrier screening. Eur J Hum Genet (2007) 0.91
Effects of early-life environment and epigenetics on cardiovascular disease risk in children: highlighting the role of twin studies. Pediatr Res (2013) 0.90
Cohort profile: The peri/post-natal epigenetic twins study. Int J Epidemiol (2011) 0.90
Genome-scale case-control analysis of CD4+ T-cell DNA methylation in juvenile idiopathic arthritis reveals potential targets involved in disease. Clin Epigenetics (2012) 0.89
Exploring the utility of human DNA methylation arrays for profiling mouse genomic DNA. Genomics (2013) 0.88
Alternative mammary oncogenic pathways are induced by D-type cyclins; MMTV-cyclin D3 transgenic mice develop squamous cell carcinoma. Oncogene (2003) 0.88
The Peri/postnatal Epigenetic Twins Study (PETS). Twin Res Hum Genet (2012) 0.88
Expression discordance of monozygotic twins at birth: effect of intrauterine environment and a possible mechanism for fetal programming. Epigenetics (2011) 0.87
DNA methylation of the IGF2/H19 imprinting control region and adiposity distribution in young adults. Clin Epigenetics (2012) 0.87
Investigating the potential role of genetic and epigenetic variation of DNA methyltransferase genes in hyperplastic polyposis syndrome. PLoS One (2011) 0.85
The importance of program evaluation: how can it be applied to diverse genetics education settings? J Genet Couns (2008) 0.84
"Did you find that out in time?": new life trajectories of parents who choose to continue a pregnancy where a genetic disorder is diagnosed or likely. Am J Med Genet A (2011) 0.84
A rapid method of genomic array analysis of scaffold/matrix attachment regions (S/MARs) identifies a 2.5-Mb region of enhanced scaffold/matrix attachment at a human neocentromere. Genome Res (2003) 0.83
Educating general practitioners about prenatal testing: approaches and challenges. Prenat Diagn (2005) 0.83
Experiences at the time of diagnosis of parents who have a child with a bone dysplasia resulting in short stature. Am J Med Genet A (2003) 0.82
Research performance evaluation: the experience of an independent medical research institute. Aust Health Rev (2012) 0.82
Intersections of epigenetics, twinning and developmental asymmetries: insights into monogenic and complex diseases and a role for 3D facial analysis. Twin Res Hum Genet (2011) 0.81
DNA methylation and miRNA expression profiling in childhood B-cell acute lymphoblastic leukemia. Epigenomics (2010) 0.81
Epigenetic discordance at imprinting control regions in twins. Epigenomics (2011) 0.80
Effects of scaffold/matrix alteration on centromeric function and gene expression. J Biol Chem (2004) 0.79
The utility of dried blood spots for proteomic studies: looking forward to looking back. Proteomics Clin Appl (2014) 0.78
Evaluation of microRNA expression in patient bone marrow aspirate slides. PLoS One (2012) 0.78
Study protocol: Asking QUestions about Alcohol in pregnancy (AQUA): a longitudinal cohort study of fetal effects of low to moderate alcohol exposure. BMC Pregnancy Childbirth (2014) 0.77
QTc prolongation: possible association with risperidone and/or haloperidol. Psychosomatics (2003) 0.77
It's "back to school" for genetic screening. Eur J Hum Genet (2006) 0.75
Why do people choose not to have screening for hemochromatosis? Genet Test Mol Biomarkers (2012) 0.75
Chimaeric twins: why monochorionicity does not guarantee monozygosity. Aust N Z J Obstet Gynaecol (2012) 0.75