Published in J Org Chem on August 19, 2005
N-Butyl-4-chloro-benzamide. Acta Crystallogr Sect E Struct Rep Online (2008) 1.58
Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy. J Med Chem (2008) 1.29
4-Chloro-N-m-tolyl-benzamide. Acta Crystallogr Sect E Struct Rep Online (2009) 0.91
2-Fluoro-N-(4-methoxy-phen-yl)benzamide. Acta Crystallogr Sect E Struct Rep Online (2009) 0.83
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Dev Cell (2008) 5.67
Loss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease. Hepatology (2008) 2.05
Synthesis of a stable compound with fivefold bonding between two chromium(I) centers. Science (2005) 1.96
Methylene-bridged glycoluril dimers: synthetic methods. J Org Chem (2002) 1.96
Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Mol Pharmacol (2005) 1.80
Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. J Immunol (2005) 1.47
Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium. Hepatology (2003) 1.46
Reversible reactions of ethylene with distannynes under ambient conditions. Science (2009) 1.46
Identification of 2-nonynoic acid, a cosmetic component, as a potential trigger of primary biliary cirrhosis. J Autoimmun (2006) 1.41
Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy. J Med Chem (2008) 1.29
Synthesis and relaxometric studies of a dendrimer-based pH-responsive MRI contrast agent. Chemistry (2008) 1.28
Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease. J Med Chem (2011) 1.25
Isolation of a stable, acyclic, two-coordinate silylene. J Am Chem Soc (2012) 1.23
C-O bond formation by polyketide synthases. Science (2002) 1.23
Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. J Immunol (2003) 1.21
4'-Methyl-4,5'-bithiazole-based correctors of defective delta F508-CFTR cellular processing. Bioorg Med Chem Lett (2008) 1.16
Interpenetrating As20 fullerene and Ni12 icosahedra in the onion-skin [As@Ni12@As20]3- ion. Science (2003) 1.16
Regarding the stability of d(0) monocyclopentadienyl zirconium acetamidinate complexes bearing alkyl substituents with beta-hydrogens. J Am Chem Soc (2002) 1.13
Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization. J Immunol (2007) 1.12
An oxazolo[3,2-b]indazole route to 1H-indazolones. Org Lett (2009) 1.12
Magnetic properties and negative colossal magnetoresistance of the rare earth Zintl phase EuIn2As2. Inorg Chem (2008) 1.09
Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis. Mol Pharmacol (2011) 1.07
Oxidative stress caused by pyocyanin impairs CFTR Cl(-) transport in human bronchial epithelial cells. Free Radic Biol Med (2008) 1.05
Pyrazolylthiazole as DeltaF508-cystic fibrosis transmembrane conductance regulator correctors with improved hydrophilicity compared to bithiazoles. J Med Chem (2010) 1.04
CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. Am J Physiol Lung Cell Mol Physiol (2003) 1.03
Ion channel formation from a calix[4]arene amide that binds HCl. J Am Chem Soc (2002) 1.02
Titanium-catalyzed stereoselective synthesis of spirooxindole oxazolines. Org Lett (2010) 1.01
A facile synthesis of new 5H-indazolo[3,2-b]benzo[d]-1,3-oxazines via one-pot intramolecular Bis-heterocyclizations. J Org Chem (2007) 1.01
Catalytic asymmetric synthesis of substituted 3-hydroxy-2-oxindoles. Angew Chem Int Ed Engl (2010) 1.00
Synthesis of (-)-viriditoxin: a 6,6'-binaphthopyran-2-one that targets the bacterial cell division protein FtsZ. Angew Chem Int Ed Engl (2011) 0.98
N,N-bond-forming heterocyclization: synthesis of 3-alkoxy-2H-indazoles. J Org Chem (2006) 0.98
Profiling base excision repair glycosylases with synthesized transition state analogs. Bioorg Med Chem Lett (2011) 0.98
Fluoride-selective host based on anion-pi interactions, ion pairing, and hydrogen bonding: synthesis and fluoride-ion sandwich complex. Angew Chem Int Ed Engl (2007) 0.97
The Davis-Beirut reaction: N1,N2-disubstituted-1H-indazolones via 1,6-electrophilic addition to 3-alkoxy-2H-indazoles. Org Lett (2011) 0.97
Diastereoselective formation of glycoluril dimers: isomerization mechanism and implications for cucurbit[n]uril synthesis. J Am Chem Soc (2002) 0.97
Synthesis of a library of 2-alkyl-3-alkyloxy-2H-indazole-6-carboxamides. J Comb Chem (2007) 0.96
Molecular clips form isostructural dimeric aggregates from benzene to water. J Am Chem Soc (2004) 0.96
Antimitochondrial antibody heterogeneity and the xenobiotic etiology of primary biliary cirrhosis. Hepatology (2013) 0.96
A one-pot-three-step route to triazolotriazepinoindazolones from oxazolino-2H-indazoles. Org Lett (2012) 0.96
Carbodiimide-based benzimidazole library method. J Comb Chem (2006) 0.96
Nucleophilic substitution of oxazino-/oxazolino-/benzoxazin [3,2-b]indazoles: an effective route to 1H-indazolones. Org Lett (2010) 0.96
Lipophilic G-quadruplexes are self-assembled ion pair receptors, and the bound anion modulates the kinetic stability of these complexes. J Am Chem Soc (2003) 0.96
Environment and primary biliary cirrhosis: electrophilic drugs and the induction of AMA. J Autoimmun (2013) 0.95
A spiroisoxazolinoproline-based amino acid scaffold for solid phase and one-bead-one-compound library synthesis. J Comb Chem (2007) 0.95
Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR. Bioorg Med Chem Lett (2009) 0.95
Highly potent, water soluble benzimidazole antagonist for activated alpha 4 beta 1 integrin. J Med Chem (2007) 0.93
Facile activation of dihydrogen by an unsaturated heavier main group compound. J Am Chem Soc (2005) 0.93
Intramolecular cycloaddition of azomethine ylides in the preparation of pyrrolidino[2',3':3,4]pyrrolidino[1,2- a]benzimidazoles. Org Lett (2007) 0.93
Orthogonally protected thiazole and isoxazole diamino acids: an efficient synthetic route. Chemistry (2010) 0.93
Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. J Immunol (2004) 0.92
Stereocontrol in asymmetric γ-lactam syntheses from imines and cyanosuccinic anhydrides. Org Lett (2013) 0.92
Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain. Bioorg Med Chem (2003) 0.92
A new synthetic route to (North)-methanocarba nucleosides designed as A3 adenosine receptor agonists. J Org Chem (2005) 0.92
Synthesis of a γ-lactam library via formal cycloaddition of imines and substituted succinic anhydrides. ACS Comb Sci (2012) 0.91
Heterocycle-heterocycle strategies: (2-nitrophenyl)isoxazole precursors to 4-aminoquinolines, 1H-indoles, and quinolin-4(1H)-ones. Org Lett (2013) 0.91
Facile syntheses of novel benzo-1,3-dioxolo-, benzothiazolo-, pyrido-, and quinolino-fused 5H-benzo[d]-pyrazolo[5,1-b][1,3]-oxazines and 1H-pyrazoles. Org Lett (2011) 0.91
Molecular clips that undergo heterochiral aggregation and self-sorting. Angew Chem Int Ed Engl (2002) 0.90
Diazocinones: synthesis and conformational analysis. J Org Chem (2006) 0.90
Electrophile-modified lipoic derivatives of PDC-E2 elicits anti-mitochondrial antibody reactivity. J Autoimmun (2011) 0.90
Ammonia synthons for the multicomponent assembly of complex gamma-lactams. Proc Natl Acad Sci U S A (2011) 0.89
Oxatriquinane and oxatriquinacene: extraordinary oxonium ions. J Am Chem Soc (2008) 0.89
Targeting multiple chorismate-utilizing enzymes with a single inhibitor: validation of a three-stage design. J Med Chem (2010) 0.88
One-step synthesis of complex nitrogen heterocycles from imines and alkyl-substituted maleic anhydrides. Org Lett (2009) 0.88
Four psychrotolerant species with high chemical diversity consistently producing cycloaspeptide A, Penicillium jamesonlandense sp. nov., Penicillium ribium sp. nov., Penicillium soppii and Penicillium lanosum. Int J Syst Evol Microbiol (2006) 0.88
Aminodeoxychorismate synthase inhibitors from one-bead one-compound combinatorial libraries: "staged" inhibitor design. J Med Chem (2006) 0.88
Efficient syntheses of the unknown quinolino[2,3-c]cinnolines; synthesis of neocryptolepines. Org Lett (2010) 0.88
Xenobiotics and autoimmunity: does acetaminophen cause primary biliary cirrhosis? Trends Mol Med (2012) 0.88
Isoxazolodihydropyridinones: 1,3-dipolar cycloaddition of nitrile oxides onto 2,4-dioxopiperidines. ACS Comb Sci (2012) 0.87
Comparison of solid-phase and solution-phase chiral auxiliaries in the alkylation/iodolactonization sequence to gamma-butyrolactones. J Org Chem (2002) 0.87
Synthesis of spiro-fused pyrazolidoylisoxazolines. J Org Chem (2011) 0.87
OBOC small-molecule combinatorial library encoded by halogenated mass-tags. Org Lett (2004) 0.87
Direct displacement of alkoxy groups of vinylogous esters by Grignard reagents. J Org Chem (2011) 0.87
Design and synthesis of propeller-shaped dispiroisoxazolinopiperidinochromanones. J Comb Chem (2008) 0.86
Regulating supramolecular function in membranes: calixarenes that enable or inhibit transmembrane Cl- transport. Angew Chem Int Ed Engl (2006) 0.86
Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in ΔF508 cystic fibrosis transmembrane conductance regulator protein. J Med Chem (2012) 0.86
Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis. Gastroenterology (2003) 0.86
Cucurbit[n]uril analogues: synthetic and mechanistic studies. J Org Chem (2005) 0.86
Two-coordinate, homoleptic manganese(II) primary terphenyl amido complexes: the effects of secondary coordination on geometry and Lewis base complexation. Dalton Trans (2009) 0.85
Parallel Synthesis of bis-heterocyclic isoxazolylmethyl- and isoxazolinylmethylpyrazoles. J Comb Chem (2010) 0.85
A novel route to fully substituted 1H-pyrazoles. J Org Chem (2005) 0.85
Catalytic Alkene Cyclization Reactions for the Stereoselective Synthesis of Complex "Terpenoid-like" Heterocycles. Chem Sci (2012) 0.85
Dispersion force stabilized two-coordinate transition metal-amido complexes of the -N(SiMe3)Dipp (Dipp = C6H3-2,6-Pr(i)2) ligand: structural, spectroscopic, magnetic, and computational studies. Inorg Chem (2013) 0.85
Reactions of the heavier group 14 element alkyne analogues Ar'EEAr' (Ar' = C6H3-2,6(C6H3-2,6-Pri2)2; E = Ge, Sn) with unsaturated molecules: probing the character of the EE multiple bonds. J Am Chem Soc (2005) 0.84
One-pot, two-step cascade synthesis of quinazolinotriazolobenzodiazepines. Org Lett (2012) 0.84
Cucurbit[n]uril analogues. Org Lett (2003) 0.84
7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove. Org Biomol Chem (2012) 0.83
Selectively targeting T- and B-cell lymphomas: a benzothiazole antagonist of alpha4beta1 integrin. J Med Chem (2009) 0.83
Asymmetric catalysis: resin-bound hydroxyprolylthreonine derivatives in enamine-mediated reactions. Angew Chem Int Ed Engl (2008) 0.83
Selective nucleophilic chemistry in the synthesis of 5-carbamoyl-3-sulfanylmethylisoxazole-4-carboxylic acids. J Comb Chem (2007) 0.83