Heterodimerization of g protein-coupled receptors: specificity and functional significance.

PubWeight™: 2.25‹?› | Rank: Top 2%

🔗 View Article (PMID 16109836)

Published in Pharmacol Rev on September 01, 2005

Authors

Steven C Prinster1, Chris Hague, Randy A Hall

Author Affiliations

1: Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA.

Articles citing this

(truncated to the top 100)

Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer. J Biol Chem (2007) 2.59

Fine-tuning of GPCR activity by receptor-interacting proteins. Nat Rev Mol Cell Biol (2009) 2.39

Increased abundance of opioid receptor heteromers after chronic morphine administration. Sci Signal (2010) 1.90

A constitutively active GPCR governs morphogenic transitions in Cryptococcus neoformans. EMBO J (2009) 1.68

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization. EMBO J (2006) 1.64

Opsin is present as dimers in COS1 cells: identification of amino acids at the dimeric interface. Proc Natl Acad Sci U S A (2006) 1.57

Molecular mechanisms of opioid receptor-dependent signaling and behavior. Anesthesiology (2011) 1.50

A day in the life of a G protein-coupled receptor: the contribution to function of G protein-coupled receptor dimerization. Br J Pharmacol (2007) 1.47

Probes for narcotic receptor mediated phenomena. 37. Synthesis and opioid binding affinity of the final pair of oxide-bridged phenylmorphans, the ortho- and para-b-isomers and their N-phenethyl analogues, and the synthesis of the N-phenethyl analogues of the ortho- and para-d-isomers. J Med Chem (2008) 1.44

Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers. EMBO Rep (2006) 1.31

G protein-coupled receptor heteromerization: a role in allosteric modulation of ligand binding. Mol Pharmacol (2011) 1.27

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors. Br J Pharmacol (2009) 1.25

Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: studies in dopamine receptor knockout mice. Am J Physiol Heart Circ Physiol (2007) 1.21

Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling. Sci Signal (2011) 1.18

Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes. Br J Pharmacol (2008) 1.15

Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention. Mol Endocrinol (2009) 1.14

Neurotransmitter receptor heteromers and their integrative role in 'local modules': the striatal spine module. Brain Res Rev (2007) 1.14

Standard opioid agonists activate heteromeric opioid receptors: evidence for morphine and [d-Ala(2)-MePhe(4)-Glyol(5)]enkephalin as selective μ-δ agonists. ACS Chem Neurosci (2009) 1.13

CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells. Proc Natl Acad Sci U S A (2010) 1.11

Introduction to adenosine receptors as therapeutic targets. Handb Exp Pharmacol (2009) 1.10

Heterodimerization and surface localization of G protein coupled receptors. Biochem Pharmacol (2006) 1.09

G-protein-coupled receptor heteromers: function and ligand pharmacology. Br J Pharmacol (2007) 1.07

Secretin receptor oligomers form intracellularly during maturation through receptor core domains. Biochemistry (2006) 1.05

D1-D2 dopamine receptor synergy promotes calcium signaling via multiple mechanisms. Mol Pharmacol (2013) 1.05

The cannabinoid receptor CB1 modulates the signaling properties of the lysophosphatidylinositol receptor GPR55. J Biol Chem (2012) 1.05

Protease-activated receptor 1 (PAR1) and PAR4 heterodimers are required for PAR1-enhanced cleavage of PAR4 by α-thrombin. J Biol Chem (2013) 1.04

Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. BMC Bioinformatics (2007) 1.04

The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis. Nat Commun (2012) 1.04

Retracted Structure of the parathyroid hormone receptor C terminus bound to the G-protein dimer Gbeta1gamma2. Structure (2008) 1.02

Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors. J Biol Chem (2009) 1.02

Post-synaptic density-95 (PSD-95) binding capacity of G-protein-coupled receptor 30 (GPR30), an estrogen receptor that can be identified in hippocampal dendritic spines. J Biol Chem (2013) 1.01

δ-opioid receptor and somatostatin receptor-4 heterodimerization: possible implications in modulation of pain associated signaling. PLoS One (2014) 0.98

Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signaling. Am J Physiol Heart Circ Physiol (2011) 0.97

Internalization dissociates β2-adrenergic receptors. PLoS One (2011) 0.95

Heteromerization of human cytomegalovirus encoded chemokine receptors. Biochem Pharmacol (2011) 0.94

Enhancement of the surface expression of G protein-coupled receptors. Trends Biotechnol (2009) 0.94

Mapping human protease-activated receptor 4 (PAR4) homodimer interface to transmembrane helix 4. J Biol Chem (2012) 0.93

Third-party bioluminescence resonance energy transfer indicates constitutive association of membrane proteins: application to class a g-protein-coupled receptors and g-proteins. Biophys J (2010) 0.93

Quantification of D1 and D5 dopamine receptor localization in layers I, III, and V of Macaca mulatta prefrontal cortical area 9: coexpression in dendritic spines and axon terminals. J Comp Neurol (2008) 0.92

A novel synthetic bivalent ligand to probe chemokine receptor CXCR4 dimerization and inhibit HIV-1 entry. Biochemistry (2012) 0.92

Evolution of color vision in pierid butterflies: blue opsin duplication, ommatidial heterogeneity and eye regionalization in Colias erate. J Comp Physiol A Neuroethol Sens Neural Behav Physiol (2009) 0.91

Chaperoning G protein-coupled receptors: from cell biology to therapeutics. Endocr Rev (2014) 0.91

Receptor heterodimerization: a new level of cross-talk. J Clin Invest (2006) 0.91

Adenosine A2A receptor is involved in cell surface expression of A2B receptor. J Biol Chem (2010) 0.91

Nuclear localization drives α1-adrenergic receptor oligomerization and signaling in cardiac myocytes. Cell Signal (2011) 0.88

Pharmacological properties of Chinese hamster ovary cells coexpressing two vasoactive intestinal peptide receptors (hVPAC1 and hVPAC2). Br J Pharmacol (2006) 0.87

Taking two to tango: a role for ghrelin receptor heterodimerization in stress and reward. Front Neurosci (2013) 0.87

Basic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor Heteromerization. Front Pharmacol (2016) 0.87

Characterization of the structure of RAMP1 by mutagenesis and molecular modeling. Biophys J (2006) 0.86

GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactions. Biochemistry (2009) 0.86

Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design framework. Biophys J (2008) 0.86

Intracellular α(2C)-adrenoceptors: storage depot, stunted development or signaling domain? Biochim Biophys Acta (2011) 0.86

The Angiotensin II Type 2 Receptor in Brain Functions: An Update. Int J Hypertens (2012) 0.85

G-protein-coupled receptor heteromer dynamics. J Cell Sci (2010) 0.85

In search of analgesia: emerging roles of GPCRs in pain. Mol Interv (2009) 0.85

Functional relevance of μ-δ opioid receptor heteromerization: a role in novel signaling and implications for the treatment of addiction disorders: from a symposium on new concepts in mu-opioid pharmacology. Drug Alcohol Depend (2011) 0.85

Insights from the analysis of conserved motifs and permitted amino acid exchanges in the human, the fly and the worm GPCR clusters. Bioinformation (2011) 0.85

Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2alpha glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins Other Lipid Mediat (2010) 0.84

Calorimetric studies of bovine rod outer segment disk membranes support a monomeric unit for both rhodopsin and opsin. Biophys J (2008) 0.83

Adrenergic activation of electrogenic K+ secretion in guinea pig distal colonic epithelium: involvement of beta1- and beta2-adrenergic receptors. Am J Physiol Gastrointest Liver Physiol (2009) 0.83

Cross-talk between alpha1D-adrenoceptors and transient receptor potential vanilloid type 1 triggers prostate cancer cell proliferation. BMC Cancer (2014) 0.83

Pharmacological endothelin receptor interaction does not occur in veins from ET(B) receptor deficient rats. Vascul Pharmacol (2008) 0.83

Purinergic signalling in endocrine organs. Purinergic Signal (2013) 0.82

Crx broadly modulates the pineal transcriptome. J Neurochem (2011) 0.82

Advances in the Development and Application of Computational Methodologies for Structural Modeling of G-Protein Coupled Receptors. Expert Opin Drug Discov (2008) 0.81

Computational study of the heterodimerization between mu and delta receptors. J Comput Aided Mol Des (2009) 0.81

Descending control of itch transmission by the serotonergic system via 5-HT1A-facilitated GRP-GRPR signaling. Neuron (2014) 0.81

The role of sweet taste in satiation and satiety. Nutrients (2014) 0.81

Adrenergic activation of electrogenic K+ secretion in guinea pig distal colonic epithelium: desensitization via the Y2-neuropeptide receptor. Am J Physiol Gastrointest Liver Physiol (2009) 0.81

α1-adrenergic receptor signaling in osteoblasts regulates clock genes and bone morphogenetic protein 4 expression through up-regulation of the transcriptional factor nuclear factor IL-3 (Nfil3)/E4 promoter-binding protein 4 (E4BP4). J Biol Chem (2014) 0.81

The Orphan G Protein-coupled Receptor Gpr175 (Tpra40) Enhances Hedgehog Signaling by Modulating cAMP Levels. J Biol Chem (2015) 0.81

The N-terminal HSDCIF motif is required for cell surface trafficking and dimerization of family B G protein coupled receptor PAC1. PLoS One (2012) 0.80

Cross-receptor interactions between dopamine D2L and neurotensin NTS1 receptors modulate binding affinities of dopaminergics. ACS Chem Neurosci (2011) 0.80

Functional characterization of G-protein-coupled receptors: a bioinformatics approach. Neuroscience (2014) 0.80

G-protein-coupled receptor heteromers or how neurons can display differently flavoured patterns in response to the same neurotransmitter. Br J Pharmacol (2009) 0.80

An in vivo demonstration of functional G protein-coupled receptor dimers. Proc Natl Acad Sci U S A (2010) 0.80

Coexpression of human somatostatin receptor-2 (SSTR2) and SSTR3 modulates antiproliferative signaling and apoptosis. J Mol Signal (2012) 0.80

Membrane-Mediated Oligomerization of G Protein Coupled Receptors and Its Implications for GPCR Function. Front Physiol (2016) 0.79

A Comparative Study of Impedance versus Optical Label-Free Systems Relative to Labelled Assays in a Predominantly Gi Coupled GPCR (C5aR) Signalling. Biosensors (Basel) (2012) 0.79

Diverse roles of G-protein coupled receptors in the regulation of neurohypophyseal hormone secretion. J Neuroendocrinol (2012) 0.79

Inhibition of angiotensin II Gq signaling augments beta-adrenergic receptor mediated effects in a renal artery stenosis model of high blood pressure. J Mol Cell Cardiol (2008) 0.79

Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression. J Biol Chem (2016) 0.79

Putative kappa opioid heteromers as targets for developing analgesics free of adverse effects. J Med Chem (2014) 0.78

Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway. J Mol Signal (2011) 0.78

Biological Significance of GPCR Heteromerization in the Neuro-Endocrine System. Front Endocrinol (Lausanne) (2011) 0.78

Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction. Front Neurosci (2015) 0.78

Light on the structure of thromboxane A₂receptor heterodimers. Cell Mol Life Sci (2011) 0.78

Differential mechanisms of activation of the Ang peptide receptors AT1, AT2, and MAS: using in silico techniques to differentiate the three receptors. PLoS One (2013) 0.78

Purinergic receptor-mediated Ca signaling in the olfactory bulb and the neurogenic area of the lateral ventricles. Purinergic Signal (2010) 0.78

Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion. Sens Actuators B Chem (2013) 0.77

D1-dopamine and α1-adrenergic receptors co-localize in dendrites of the rat prefrontal cortex. Neuroscience (2013) 0.77

Cross-Genome Clustering of Human and C. elegans G-Protein Coupled Receptors. Evol Bioinform Online (2012) 0.77

Feeding and the rhodopsin family g-protein coupled receptors in nematodes and arthropods. Front Endocrinol (Lausanne) (2012) 0.76

Identifying a Neuromedin U Receptor 2 Splice Variant and Determining Its Roles in the Regulation of Signaling and Tumorigenesis In Vitro. PLoS One (2015) 0.76

Differential effects of prostaglandin E2-sensitive receptors on contractility of human ocular cells that regulate conventional outflow. Invest Ophthalmol Vis Sci (2013) 0.76

Systematic protein-protein interaction mapping for clinically relevant human GPCRs. Mol Syst Biol (2017) 0.75

Dynorphin-Dependent Reduction of Excitability and Attenuation of Inhibitory Afferents of NPS Neurons in the Pericoerulear Region of Mice. Front Cell Neurosci (2016) 0.75

Clarifying the Ghrelin System's Ability to Regulate Feeding Behaviours Despite Enigmatic Spatial Separation of the GHSR and Its Endogenous Ligand. Int J Mol Sci (2017) 0.75

Dopamine acting at D1-like, D2-like and α1-adrenergic receptors differentially modulates theta and gamma oscillatory activity in primary motor cortex. PLoS One (2017) 0.75

A1 Adenosine Receptor Activation Modulates Central Nervous System Development and Repair. Mol Neurobiol (2016) 0.75

Articles by these authors

Fine-tuning of GPCR activity by receptor-interacting proteins. Nat Rev Mol Cell Biol (2009) 2.39

The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases. Annu Rev Physiol (2006) 2.18

Cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors. J Biol Chem (2004) 1.75

RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signaling. J Biol Chem (2004) 1.57

Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins. J Biol Chem (2005) 1.52

Heterodimerization with beta2-adrenergic receptors promotes surface expression and functional activity of alpha1D-adrenergic receptors. J Pharmacol Exp Ther (2004) 1.50

P2Y1 receptor signaling is controlled by interaction with the PDZ scaffold NHERF-2. Proc Natl Acad Sci U S A (2005) 1.48

LPA2 receptor mediates mitogenic signals in human colon cancer cells. Am J Physiol Cell Physiol (2005) 1.47

Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K+ channels. J Gen Physiol (2009) 1.45

GLAST stability and activity are enhanced by interaction with the PDZ scaffold NHERF-2. Neurosci Lett (2010) 1.43

The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity. J Biol Chem (2011) 1.35

Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome. J Biol Chem (2008) 1.30

Differential synaptology of vGluT2-containing thalamostriatal afferents between the patch and matrix compartments in rats. J Comp Neurol (2006) 1.23

Heterodimerization of alpha 2A- and beta 1-adrenergic receptors. J Biol Chem (2003) 1.23

Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system. Mol Cell Proteomics (2008) 1.18

Erbin enhances voltage-dependent facilitation of Ca(v)1.3 Ca2+ channels through relief of an autoinhibitory domain in the Ca(v)1.3 alpha1 subunit. J Neurosci (2007) 1.17

GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function. J Biol Chem (2006) 1.16

Hetero-oligomerization between GABAA and GABAB receptors regulates GABAB receptor trafficking. J Biol Chem (2004) 1.16

Olfactory receptor surface expression is driven by association with the beta2-adrenergic receptor. Proc Natl Acad Sci U S A (2004) 1.14

Adhesion G protein-coupled receptors: signaling, pharmacology, and mechanisms of activation. Mol Pharmacol (2012) 1.10

Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction. J Biol Chem (2006) 1.09

Disease-causing mutation in GPR54 reveals the importance of the second intracellular loop for class A G-protein-coupled receptor function. J Biol Chem (2008) 1.08

Subtype-specific dimerization of alpha 1-adrenoceptors: effects on receptor expression and pharmacological properties. Mol Pharmacol (2003) 1.07

MAGI-3 regulates LPA-induced activation of Erk and RhoA. Cell Signal (2006) 1.07

Interaction with cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) inhibits beta1-adrenergic receptor surface expression. J Biol Chem (2004) 1.06

Differential synaptic plasticity of the corticostriatal and thalamostriatal systems in an MPTP-treated monkey model of parkinsonism. Eur J Neurosci (2008) 1.06

Genome-wide functional annotation of dual-specificity protein- and lipid-binding modules that regulate protein interactions. Mol Cell (2012) 1.05

The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity. J Biol Chem (2009) 1.04

Heterodimers of alpha1B- and alpha1D-adrenergic receptors form a single functional entity. Mol Pharmacol (2005) 1.04

Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity. Chem Biol (2009) 1.03

Na/H exchanger regulatory factors control parathyroid hormone receptor signaling by facilitating differential activation of G(alpha) protein subunits. J Biol Chem (2010) 1.02

Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the monkey subthalamic nucleus. J Comp Neurol (2004) 1.01

The PDZ scaffold NHERF-2 interacts with mGluR5 and regulates receptor activity. J Biol Chem (2006) 1.00

GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin. Proc Natl Acad Sci U S A (2013) 0.99

A C-terminal class I PDZ binding motif of EspI/NleA modulates the virulence of attaching and effacing Escherichia coli and Citrobacter rodentium. Cell Microbiol (2007) 0.98

Specificity of olfactory receptor interactions with other G protein-coupled receptors. J Biol Chem (2007) 0.97

Cocaine- and amphetamine-regulated transcript (CART) peptide activates the extracellular signal-regulated kinase (ERK) pathway in AtT20 cells via putative G-protein coupled receptors. Neurosci Lett (2005) 0.97

Agonist-induced polarized trafficking and surface expression of the adenosine 2b receptor in intestinal epithelial cells: role of SNARE proteins. Am J Physiol Gastrointest Liver Physiol (2004) 0.96

The role of norepinephrine in differential response to stress in an animal model of posttraumatic stress disorder. Biol Psychiatry (2011) 0.96

MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells. Gastroenterology (2010) 0.95

Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1). J Biol Chem (2011) 0.95

Binding to Na(+) /H(+) exchanger regulatory factor 2 (NHERF2) affects trafficking and function of the enteropathogenic Escherichia coli type III secretion system effectors Map, EspI and NleH. Cell Microbiol (2010) 0.94

kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins. J Biol Chem (2004) 0.94

Enhancement of the surface expression of G protein-coupled receptors. Trends Biotechnol (2009) 0.94

Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome. Proc Natl Acad Sci U S A (2010) 0.93

JAM-A associates with ZO-2, afadin, and PDZ-GEF1 to activate Rap2c and regulate epithelial barrier function. Mol Biol Cell (2013) 0.93

BAI1 regulates spatial learning and synaptic plasticity in the hippocampus. J Clin Invest (2015) 0.92

Astrocytic and neuronal localization of the scaffold protein Na+/H+ exchanger regulatory factor 2 (NHERF-2) in mouse brain. J Comp Neurol (2006) 0.92

Alpha2C-adrenergic receptors exhibit enhanced surface expression and signaling upon association with beta2-adrenergic receptors. J Pharmacol Exp Ther (2006) 0.92

Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density. J Biol Chem (2013) 0.91

CART peptide stimulation of G protein-mediated signaling in differentiated PC12 cells: identification of PACAP 6-38 as a CART receptor antagonist. Neuropeptides (2011) 0.91

Localization and expression of group I metabotropic glutamate receptors in the mouse striatum, globus pallidus, and subthalamic nucleus: regulatory effects of MPTP treatment and constitutive Homer deletion. J Neurosci (2007) 0.91

Glycosylation of beta(1)-adrenergic receptors regulates receptor surface expression and dimerization. Biochem Biophys Res Commun (2002) 0.90

An electron microscope immunocytochemical study of GABA(B) R2 receptors in the monkey basal ganglia: a comparative analysis with GABA(B) R1 receptor distribution. J Comp Neurol (2004) 0.88

Cell cycle-dependent phosphorylation of Disabled-2 by cdc2. Oncogene (2003) 0.87

Evidence against enhanced glutamate transport in the anticonvulsant mechanism of the ketogenic diet. Epilepsy Res (2007) 0.86

GPR37 surface expression enhancement via N-terminal truncation or protein-protein interactions. Biochemistry (2009) 0.86

Novel interaction between the M4 muscarinic acetylcholine receptor and elongation factor 1A2. J Biol Chem (2002) 0.85

Interaction between metabotropic glutamate receptor 7 and alpha tubulin. J Neurochem (2002) 0.85

Elucidation of a novel extracellular calcium-binding site on metabotropic glutamate receptor 1{alpha} (mGluR1{alpha}) that controls receptor activation. J Biol Chem (2010) 0.85

Adenosine A2A receptor in the monkey basal ganglia: ultrastructural localization and colocalization with the metabotropic glutamate receptor 5 in the striatum. J Comp Neurol (2012) 0.84

Subtype-selective noncompetitive or competitive inhibition of human alpha1-adrenergic receptors by rho-TIA. J Biol Chem (2004) 0.84

A new human NHERF1 mutation decreases renal phosphate transporter NPT2a expression by a PTH-independent mechanism. PLoS One (2012) 0.83

Design of a selective chemical probe for class I PDZ domains. Bioorg Med Chem Lett (2006) 0.82

Role of SAP97 protein in the regulation of corticotropin-releasing factor receptor 1 endocytosis and extracellular signal-regulated kinase 1/2 signaling. J Biol Chem (2013) 0.82

Differential regulation of GPR54 transcription by specificity protein-1 and partial estrogen response element in mouse pituitary cells. Biochem Biophys Res Commun (2010) 0.80

Syntrophin isoforms play specific functional roles in the α1D-adrenergic receptor/DAPC signalosome. Biochem Biophys Res Commun (2011) 0.80

GABA(B) receptors in the centromedian/parafascicular thalamic nuclear complex: an ultrastructural analysis of GABA(B)R1 and GABA(B)R2 in the monkey thalamus. J Comp Neurol (2006) 0.80

Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α. J Biol Chem (2013) 0.78

Olfactory receptor localization and function: an emerging role for GPCR heterodimerization. Mol Interv (2004) 0.78

New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors. Ann N Y Acad Sci (2014) 0.78

SAP97 promotes the stability of Nax channels at the plasma membrane. FEBS Lett (2012) 0.78

D-AKAP2:PKA RII:PDZK1 ternary complex structure: insights from the nucleation of a polyvalent scaffold. Protein Sci (2014) 0.76

Detection and characterization of receptor interactions with PDZ domains. Methods Mol Biol (2011) 0.75

Identification of novel G protein-coupled receptor-interacting proteins. Methods Enzymol (2002) 0.75