Published in Am J Physiol Heart Circ Physiol on August 19, 2005
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Mapping the contribution of beta3-containing GABAA receptors to volatile and intravenous general anesthetic actions. BMC Pharmacol (2007) 1.06
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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science (2007) 20.32
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Crystal structure of the µ-opioid receptor bound to a morphinan antagonist. Nature (2012) 6.18
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Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature (2010) 3.19
Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II. J Clin Invest (2003) 3.15
Prevention of pediatric graft coronary artery disease: atorvastatin. Pediatr Transplant (2008) 2.79
Temporal response of the human virome to immunosuppression and antiviral therapy. Cell (2013) 2.72
Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states. J Biol Chem (2003) 2.68
Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants. Nat Immunol (2005) 2.60
Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature (2013) 2.49
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High-resolution crystal structure of human protease-activated receptor 1. Nature (2012) 2.44
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor. Nature (2011) 2.43
Accuracy of interpretation of preparticipation screening electrocardiograms. J Pediatr (2011) 2.28
The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo. Cardiovasc Res (2005) 2.24
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature (2013) 2.14
Hypoplastic left heart syndrome: current considerations and expectations. J Am Coll Cardiol (2012) 2.10
Energy landscapes as a tool to integrate GPCR structure, dynamics, and function. Physiology (Bethesda) (2010) 2.05
Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex. Proc Natl Acad Sci U S A (2011) 2.03
Success rates in pediatric WPW ablation are improved with 3-dimensional mapping systems compared with fluoroscopy alone: a multicenter study. J Cardiovasc Electrophysiol (2015) 2.01
Counting low-copy number proteins in a single cell. Science (2007) 2.01
A multicenter experience with novel implantable cardioverter defibrillator configurations in the pediatric and congenital heart disease population. J Cardiovasc Electrophysiol (2006) 1.95
Antithetic regulation by beta-adrenergic receptors of Gq receptor signaling via phospholipase C underlies the airway beta-agonist paradox. J Clin Invest (2003) 1.87
Ligand-regulated oligomerization of beta(2)-adrenoceptors in a model lipid bilayer. EMBO J (2009) 1.86
Ligand-specific interactions modulate kinetic, energetic, and mechanical properties of the human β2 adrenergic receptor. Structure (2012) 1.85
Myocyte adrenoceptor signaling pathways. Science (2003) 1.81
In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium. Arterioscler Thromb Vasc Biol (2011) 1.80
Nanobody stabilization of G protein-coupled receptor conformational states. Curr Opin Struct Biol (2011) 1.75
Structure-based drug screening for G-protein-coupled receptors. Trends Pharmacol Sci (2012) 1.72
The effect of bioengineered acellular collagen patch on cardiac remodeling and ventricular function post myocardial infarction. Biomaterials (2013) 1.68
FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension. J Clin Invest (2013) 1.65
The effects of dexmedetomidine on cardiac electrophysiology in children. Anesth Analg (2008) 1.64
Cryoablation versus radiofrequency ablation for treatment of pediatric atrioventricular nodal reentrant tachycardia: initial experience with 4-mm cryocatheter. Heart Rhythm (2006) 1.63
A monoclonal antibody for G protein-coupled receptor crystallography. Nat Methods (2007) 1.60
International Society for Heart and Lung Transplantation: Practice guidelines for management of heart failure in children. J Heart Lung Transplant (2004) 1.59
Dosage-dependent switch from G protein-coupled to G protein-independent signaling by a GPCR. EMBO J (2006) 1.56
Loss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans. Circ Res (2012) 1.56
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation. Nature (2016) 1.55
Cryoablation of accessory pathways in the coronary sinus in young patients: a multicenter study from the Pediatric and Congenital Electrophysiology Society's Working Group on Cryoablation. J Cardiovasc Electrophysiol (2007) 1.49
The role of ligands on the equilibria between functional states of a G protein-coupled receptor. J Am Chem Soc (2013) 1.48
Results of a multicenter retrospective implantable cardioverter-defibrillator registry of pediatric and congenital heart disease patients. J Am Coll Cardiol (2008) 1.47
Characterizing dual atrioventricular nodal physiology in pediatric patients with atrioventricular nodal reentrant tachycardia. J Cardiovasc Electrophysiol (2006) 1.46
Multi-institutional study of implantable defibrillator lead performance in children and young adults: results of the Pediatric Lead Extractability and Survival Evaluation (PLEASE) study. Circulation (2013) 1.46
Microarray analysis of gene expression after transverse aortic constriction in mice. Physiol Genomics (2004) 1.44
Insights into dyssynchrony in hypoplastic left heart syndrome. Heart Rhythm (2012) 1.41
Circadian and seasonal variation of malignant arrhythmias in a pediatric and congenital heart disease population. J Cardiovasc Electrophysiol (2002) 1.39
QRS prolongation is strongly associated with life-threatening ventricular arrhythmias in children with dilated cardiomyopathy. J Heart Lung Transplant (2013) 1.39
Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension. Circ Res (2005) 1.37
Assessment of intrathoracic impedance algorithm in the pediatric and adult congenital population. Pacing Clin Electrophysiol (2014) 1.37
Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol (2009) 1.34
Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients. J Heart Lung Transplant (2010) 1.31
Disparate distribution of 16 candidate single nucleotide polymorphisms among racial and ethnic groups of pediatric heart transplant patients. Transplantation (2006) 1.24
Structural insights into G-protein-coupled receptor activation. Curr Opin Struct Biol (2008) 1.22
Differential cardioprotective/cardiotoxic effects mediated by beta-adrenergic receptor subtypes. Am J Physiol Heart Circ Physiol (2005) 1.21
Genome-wide expression profiling of a cardiac pressure overload model identifies major metabolic and signaling pathway responses. J Mol Cell Cardiol (2004) 1.21
Skeletal muscle hypertrophy and anti-atrophy effects of clenbuterol are mediated by the beta2-adrenergic receptor. Muscle Nerve (2002) 1.20
Organization of beta-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes. J Cell Biol (2007) 1.19
Mutation of the alpha2A-adrenoceptor impairs working memory performance and annuls cognitive enhancement by guanfacine. J Neurosci (2002) 1.18
A fluorescent probe designed for studying protein conformational change. Proc Natl Acad Sci U S A (2005) 1.17
N-terminal T4 lysozyme fusion facilitates crystallization of a G protein coupled receptor. PLoS One (2012) 1.17
Molecular and physiological characterization of RV remodeling in a murine model of pulmonary stenosis. Am J Physiol Heart Circ Physiol (2008) 1.14
The role of beta-adrenergic receptor signaling in cardioprotection. FASEB J (2005) 1.13
Recommendations from the Heart Rhythm Society Task Force on Lead Performance Policies and Guidelines: developed in collaboration with the American College of Cardiology (ACC) and the American Heart Association (AHA). Heart Rhythm (2009) 1.12
Abnormal cardiac function associated with sympathetic nervous system hyperactivity in mice. Am J Physiol Heart Circ Physiol (2002) 1.12
Role of detergents in conformational exchange of a G protein-coupled receptor. J Biol Chem (2012) 1.10
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor. Proc Natl Acad Sci U S A (2012) 1.09
Recruitment via the Internet and social networking sites: the 1989-1995 cohort of the Australian Longitudinal Study on Women's Health. J Med Internet Res (2014) 1.09
Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy. Nat Cell Biol (2013) 1.07
N-ethylmaleimide-sensitive factor regulates beta2 adrenoceptor trafficking and signaling in cardiomyocytes. Mol Pharmacol (2007) 1.06
Conformational dynamics of single G protein-coupled receptors in solution. J Phys Chem B (2011) 1.06
Dynamic microRNA expression during the transition from right ventricular hypertrophy to failure. Physiol Genomics (2012) 1.05
Isoflurane and nociception: spinal alpha2A adrenoceptors mediate antinociception while supraspinal alpha1 adrenoceptors mediate pronociception. Anesthesiology (2002) 1.04
Genetic polymorphisms impact the risk of acute rejection in pediatric heart transplantation: a multi-institutional study. Transplantation (2008) 1.03
Hot topics in tetralogy of Fallot. J Am Coll Cardiol (2013) 1.03
Recent advances in the treatment of Kawasaki disease. J Chin Med Assoc (2011) 1.03
The electrophysiology of atrioventricular nodal reentry tachycardia following the Mustard or Senning procedure and its radiofrequency ablation. Cardiol Young (2005) 1.02
Online and Offline Recruitment of Young Women for a Longitudinal Health Survey: Findings From the Australian Longitudinal Study on Women's Health 1989-95 Cohort. J Med Internet Res (2015) 1.01
Risk factors for recurrent rejection in pediatric heart transplantation: a multicenter experience. J Heart Lung Transplant (2004) 1.00
Heterozygous alpha 2A-adrenergic receptor mice unveil unique therapeutic benefits of partial agonists. Proc Natl Acad Sci U S A (2002) 0.99
Pediatric nonpost-operative junctional ectopic tachycardia medical management and interventional therapies. J Am Coll Cardiol (2009) 0.99
Pharmacological inhibition of βIIPKC is cardioprotective in late-stage hypertrophy. J Mol Cell Cardiol (2011) 0.99
Regulation of β2-adrenergic receptor function by conformationally selective single-domain intrabodies. Mol Pharmacol (2013) 0.98
Cardiac resynchronization therapy for pediatric patients with heart failure and congenital heart disease: a reappraisal of results. Circulation (2014) 0.96
How does the health and well-being of young Australian vegetarian and semi-vegetarian women compare with non-vegetarians? Public Health Nutr (2007) 0.96