Involvement of fractalkine/CX3CL1 expression by dendritic cells in the enhancement of host immunity against Legionella pneumophila.

PubWeight™: 0.90‹?›

🔗 View Article (PMC 1231053)

Published in Infect Immun on September 01, 2005

Authors

Toshiaki Kikuchi1, Sita Andarini, Hong Xin, Kazunori Gomi, Yutaka Tokue, Yasuo Saijo, Tasuku Honjo, Akira Watanabe, Toshihiro Nukiwa

Author Affiliations

1: Department of Respiratory Oncology and Molecular Medicine, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Aobaku, Sendai 980-8575, Japan. kikuchi@idac.tohoku.ac.jp

Articles cited by this

Immunobiology of dendritic cells. Annu Rev Immunol (2000) 23.65

Chemokines: a new classification system and their role in immunity. Immunity (2000) 13.03

Dendritic cells: specialized and regulated antigen processing machines. Cell (2001) 10.44

A new class of membrane-bound chemokine with a CX3C motif. Nature (1997) 7.87

International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol Rev (2000) 7.17

Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell (1997) 6.70

Chemokines and cell migration in secondary lymphoid organs. Science (1999) 5.18

Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation. Nature (1997) 3.74

The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood (2003) 3.51

Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1). J Biol Chem (2001) 2.91

Th1- and Th2-cell commitment during infectious disease: asymmetry in divergent pathways. Trends Immunol (2001) 2.26

Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses. J Clin Invest (2001) 2.10

Chemokine-dependent neutrophil recruitment in a murine model of Legionella pneumonia: potential role of neutrophils as immunoregulatory cells. Infect Immun (2001) 1.88

Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation. Eur J Immunol (1999) 1.88

Legionella reveal dendritic cell functions that facilitate selection of antigens for MHC class II presentation. Immunity (2003) 1.85

Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells. Eur J Immunol (1999) 1.82

How dendritic cells and microbes interact to elicit or subvert protective immune responses. Curr Opin Immunol (2002) 1.68

The role of dendritic cells in the induction and regulation of immunity to microbial infection. Curr Opin Immunol (1999) 1.64

Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4+ T cells. Nat Med (2000) 1.13

Dendritic cells pulsed with live and dead Legionella pneumophila elicit distinct immune responses. J Immunol (2004) 1.08

Dendritic cells modified to express CD40 ligand elicit therapeutic immunity against preexisting murine tumors. Blood (2000) 1.08

Legionella pneumophila pathogenesis and immunity. Semin Pediatr Infect Dis (2002) 1.05

Immunologic response and pathophysiology of Legionella infection. Semin Respir Infect (1998) 1.01

Adenovirus vector-mediated in vivo gene transfer of OX40 ligand to tumor cells enhances antitumor immunity of tumor-bearing hosts. Cancer Res (2004) 1.01

Induction of cytokine granulocyte-macrophage colony-stimulating factor and chemokine macrophage inflammatory protein 2 mRNAs in macrophages by Legionella pneumophila or Salmonella typhimurium attachment requires different ligand-receptor systems. Infect Immun (1996) 1.00

Antigen-pulsed dendritic cells expressing macrophage-derived chemokine elicit Th2 responses and promote specific humoral immunity. J Clin Invest (2001) 0.97

Chemokines and dendritic cells: a crucial alliance. Immunol Cell Biol (2002) 0.96

Monocyte chemotactic protein-3. Eur Cytokine Netw (2002) 0.94

Differential effects of virulent versus avirulent Legionella pneumophila on chemokine gene expression in murine alveolar macrophages determined by cDNA expression array technique. Infect Immun (2000) 0.82

Tumor suppression induced by intratumor administration of adenovirus vector expressing NK4, a 4-kringle antagonist of hepatocyte growth factor, and naive dendritic cells. Blood (2002) 0.80

Articles by these authors

Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med (2010) 27.12

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci U S A (2002) 12.39

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer. Proc Natl Acad Sci U S A (2007) 7.49

Prospective phase II study of gefitinib for chemotherapy-naive patients with advanced non-small-cell lung cancer with epidermal growth factor receptor gene mutations. J Clin Oncol (2006) 6.55

PD-1 and PD-1 ligands: from discovery to clinical application. Int Immunol (2007) 6.24

Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut. Proc Natl Acad Sci U S A (2004) 5.93

Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2005) 5.83

Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol (2006) 5.82

PD-L1/B7H-1 inhibits the effector phase of tumor rejection by T cell receptor (TCR) transgenic CD8+ T cells. Cancer Res (2004) 5.59

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell (2004) 5.50

Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. Cancer (2010) 5.05

The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport. Science (2008) 4.94

Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches. Science (2009) 4.80

Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. Int Immunol (2002) 4.66

Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment. Cancer Cell (2009) 4.56

The PD-1-PD-L pathway in immunological tolerance. Trends Immunol (2006) 4.52

The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors. Cancer Cell (2009) 4.47

Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity. J Immunol (2007) 4.29

Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene (2006) 4.13

First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. J Clin Oncol (2009) 4.05

Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4. Nat Immunol (2005) 4.01

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev (2004) 3.95

Severe acute interstitial pneumonia and gefitinib. Lancet (2003) 3.94

Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. Cancer Cell (2012) 3.90

AID is required for c-myc/IgH chromosome translocations in vivo. Cell (2004) 3.89

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2. Eur J Immunol (2002) 3.78

Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells. Nat Immunol (2002) 3.75

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat Med (2007) 3.70

AID mutant analyses indicate requirement for class-switch-specific cofactors. Nat Immunol (2003) 3.69

Fibulin-5/DANCE is essential for elastogenesis in vivo. Nature (2002) 3.60

Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora. Science (2002) 3.58

The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase. Nat Cell Biol (2008) 3.30

Constitutive expression of AID leads to tumorigenesis. J Exp Med (2003) 3.16

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts. Science (2002) 3.09

PD-1 inhibits antiviral immunity at the effector phase in the liver. J Exp Med (2003) 3.05

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep (2008) 3.03

Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity (2004) 3.01

Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas. Clin Cancer Res (2005) 2.97

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch. Science (2004) 2.93

Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues. Immunol Lett (2002) 2.80

Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med (2012) 2.80

AID is required for germinal center-derived lymphomagenesis. Nat Genet (2007) 2.79

Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke. Nat Neurosci (2009) 2.74

Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1. Proc Natl Acad Sci U S A (2004) 2.69

Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. J Exp Med (2003) 2.66

Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice. Nat Med (2003) 2.65

Intestinal IgA synthesis: regulation of front-line body defences. Nat Rev Immunol (2003) 2.62

B1b lymphocytes confer T cell-independent long-lasting immunity. Immunity (2004) 2.60

A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application. Nat Immunol (2013) 2.50

Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes. Proc Natl Acad Sci U S A (2005) 2.49

Heterogeneous increase in CD34-positive alveolar capillaries in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2004) 2.35

Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma. Cancer Res (2004) 2.34

Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. Cell Stem Cell (2013) 2.32

Characteristics of a large cohort of patients with autoimmune pulmonary alveolar proteinosis in Japan. Am J Respir Crit Care Med (2008) 2.29

The AID enzyme induces class switch recombination in fibroblasts. Nature (2002) 2.28

Infiltration of COX-2-expressing macrophages is a prerequisite for IL-1 beta-induced neovascularization and tumor growth. J Clin Invest (2005) 2.20

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation. J Exp Med (2002) 2.18

An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells (2013) 2.18

Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans. Development (2003) 2.18

Separate domains of AID are required for somatic hypermutation and class-switch recombination. Nat Immunol (2004) 2.06

Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity (2003) 2.03

The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors. Proc Natl Acad Sci U S A (2008) 2.03

PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells. Int Immunol (2004) 2.02

A Japanese Lung Cancer Registry study: prognosis of 13,010 resected lung cancers. J Thorac Oncol (2008) 2.01

Methylation of the KEAP1 gene promoter region in human colorectal cancer. BMC Cancer (2012) 2.01

Elevated levels of hypoxia-inducible microRNA-210 in pre-eclampsia: new insights into molecular mechanisms for the disease. J Cell Mol Med (2012) 1.99

Mutations in the SLC34A2 gene are associated with pulmonary alveolar microlithiasis. Am J Respir Crit Care Med (2006) 1.98

Regulation of lymphocyte development by Notch signaling. Nat Immunol (2007) 1.96

New regulatory co-receptors: inducible co-stimulator and PD-1. Curr Opin Immunol (2002) 1.92

Randomized phase II trial comparing amrubicin with topotecan in patients with previously treated small-cell lung cancer: North Japan Lung Cancer Study Group Trial 0402. J Clin Oncol (2008) 1.88

PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice. J Exp Med (2011) 1.80

The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy. Dev Biol (2006) 1.80

Discovery of activation-induced cytidine deaminase, the engraver of antibody memory. Adv Immunol (2007) 1.80

Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense. Nat Immunol (2011) 1.74

RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development. Development (2010) 1.72

Consensus statement for the diagnosis and treatment of drug-induced lung injuries. Respir Investig (2013) 1.70

Role of AID in tumorigenesis. Adv Immunol (2007) 1.69

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7. EMBO J (2003) 1.68

Learning and memory deficits in Notch mutant mice. Curr Biol (2003) 1.68

Expression of urocortin and corticotropin-releasing factor receptor subtypes in the human heart. J Clin Endocrinol Metab (2002) 1.66

IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity. J Immunol (2011) 1.64

DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: implications for the androgen receptor functions and regulation. FEBS Lett (2006) 1.62

Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes. Int Immunol (2009) 1.62

Cutting edge: A critical functional role for IL-23 in psoriasis. J Immunol (2010) 1.61

Inhibition of Notch/RBP-J signaling induces hair cell formation in neonate mouse cochleas. J Mol Med (Berl) (2005) 1.61

Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood (2010) 1.60

Cutting Edge: Ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease. J Immunol (2002) 1.55

The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. Immunity (2006) 1.53

The glypican 3 oncofetal protein is a promising diagnostic marker for hepatocellular carcinoma. Mod Pathol (2005) 1.52

Combined survival analysis of prospective clinical trials of gefitinib for non-small cell lung cancer with EGFR mutations. Clin Cancer Res (2009) 1.52

Multiple roles of Notch signaling in cochlear development. Dev Biol (2007) 1.48