Jürgen Bernhagen

Author PubWeight™ 86.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Investigations on DNA intercalation and surface binding by SYBR Green I, its structure determination and methodological implications. Nucleic Acids Res 2004 3.45
2 MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis. Nat Rev Drug Discov 2006 2.30
3 Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease. Microbes Infect 2002 2.10
4 Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. J Am Coll Cardiol 2011 1.95
5 Macrophage migration inhibitory factor in cardiovascular disease. Circulation 2008 1.91
6 Macrophage migration inhibitory factor (MIF) exerts antifibrotic effects in experimental liver fibrosis via CD74. Proc Natl Acad Sci U S A 2011 1.85
7 The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunity. Mol Endocrinol 2007 1.73
8 Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter. FEBS Lett 2003 1.59
9 Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart. Circulation 2010 1.56
10 Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis. Circulation 2002 1.56
11 Cytokines in sepsis: potent immunoregulators and potential therapeutic targets--an updated view. Mediators Inflamm 2013 1.54
12 A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett 2009 1.54
13 Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity. Cell Signal 2005 1.53
14 MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease. Circ Res 2009 1.49
15 Macrophage migration inhibitory factor (MIF): a promising biomarker. Drug News Perspect 2010 1.48
16 A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Mol Cell Biol 2009 1.43
17 Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment. Proc Natl Acad Sci U S A 2008 1.41
18 Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF). Atherosclerosis 2006 1.31
19 The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF). Proc Natl Acad Sci U S A 2011 1.29
20 Dual role of macrophage migration inhibitory factor (MIF) in human breast cancer. BMC Cancer 2009 1.26
21 The Golgi-associated protein p115 mediates the secretion of macrophage migration inhibitory factor. J Immunol 2009 1.25
22 Chemokine-like functions of MIF in atherosclerosis. J Mol Med (Berl) 2008 1.19
23 Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice. Circulation 2003 1.17
24 Unconventional secretion of fibroblast growth factor 2 is mediated by direct translocation across the plasma membrane of mammalian cells. J Biol Chem 2003 1.17
25 The cytokine macrophage migration inhibitory factor reduces pro-oxidative stress-induced apoptosis. J Immunol 2003 1.15
26 Macrophage migration inhibitory factor: a noncanonical chemokine important in atherosclerosis. Trends Cardiovasc Med 2009 1.13
27 Activation of the JNK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on CXCR4 and CD74. Cell Signal 2010 1.12
28 Link between macrophage migration inhibitory factor and cellular redox regulation. Antioxid Redox Signal 2005 1.11
29 Hypoxia-induced endothelial secretion of macrophage migration inhibitory factor and role in endothelial progenitor cell recruitment. J Cell Mol Med 2011 1.11
30 Cardioprotection through S-nitros(yl)ation of macrophage migration inhibitory factor. Circulation 2012 1.10
31 Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen. EMBO Rep 2009 1.08
32 Direct modification of the proinflammatory cytokine macrophage migration inhibitory factor by dietary isothiocyanates. J Biol Chem 2009 1.08
33 Mechanisms underlying the impact of humic acids on DNA quantification by SYBR Green I and consequences for the analysis of soils and aquatic sediments. Nucleic Acids Res 2003 1.07
34 A novel drug-eluting stent coated with an integrin-binding cyclic Arg-Gly-Asp peptide inhibits neointimal hyperplasia by recruiting endothelial progenitor cells. J Am Coll Cardiol 2006 1.06
35 The vascular biology of macrophage migration inhibitory factor (MIF). Expression and effects in inflammation, atherogenesis and angiogenesis. Thromb Haemost 2013 1.03
36 Identification and characterization of novel classes of macrophage migration inhibitory factor (MIF) inhibitors with distinct mechanisms of action. J Biol Chem 2010 1.01
37 Differential roles of angiogenic chemokines in endothelial progenitor cell-induced angiogenesis. Basic Res Cardiol 2012 0.99
38 A 16-residue peptide fragment of macrophage migration inhibitory factor, MIF-(50-65), exhibits redox activity and has MIF-like biological functions. J Biol Chem 2003 0.99
39 Role for CD74 and CXCR4 in clathrin-dependent endocytosis of the cytokine MIF. Eur J Cell Biol 2011 0.99
40 Circulating fibrocytes--biology and mechanisms in wound healing and scar formation. Int Rev Cell Mol Biol 2011 0.97
41 YB-1 acts as a ligand for Notch-3 receptors and modulates receptor activation. J Biol Chem 2009 0.97
42 Identification of DEAD-box RNA helicase 6 (DDX6) as a cellular modulator of vascular endothelial growth factor expression under hypoxia. J Biol Chem 2013 0.96
43 The role of macrophage migration inhibitory factor in autoimmune liver disease. Hepatology 2013 0.95
44 Compartmentalized protective and detrimental effects of endogenous macrophage migration-inhibitory factor mediated by CXCR2 in a mouse model of myocardial ischemia/reperfusion. Arterioscler Thromb Vasc Biol 2013 0.94
45 Arrest Functions of the MIF Ligand/Receptor Axes in Atherogenesis. Front Immunol 2013 0.94
46 Macrophage migration inhibitory factor (MIF) promotes fibroblast migration in scratch-wounded monolayers in vitro. FEBS Lett 2007 0.94
47 Ribosomal protein S19 interacts with macrophage migration inhibitory factor and attenuates its pro-inflammatory function. J Biol Chem 2009 0.92
48 MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism. FASEB J 2010 0.92
49 MIF: a key player in cutaneous biology and wound healing. Exp Dermatol 2011 0.90
50 High postoperative blood levels of macrophage migration inhibitory factor are associated with less organ dysfunction in patients after cardiac surgery. Mol Med 2012 0.89
51 Receptor binding and cellular uptake studies of macrophage migration inhibitory factor (MIF): use of biologically active labeled MIF derivatives. J Interferon Cytokine Res 2002 0.89
52 Macrophage migration inhibitory factor in myocardial ischaemia/reperfusion injury. Cardiovasc Res 2014 0.88
53 The impact of proteinase-induced matrix degradation on the release of VEGF from heparinized collagen matrices. Biomaterials 2005 0.87
54 Role of CSN5/JAB1 in Wnt/β-catenin activation in colorectal cancer cells. FEBS Lett 2012 0.87
55 The role of macrophage migration inhibitory factor in critical illness. Mini Rev Med Chem 2014 0.86
56 Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif. FEBS Lett 2005 0.86
57 Conformational restriction via cyclization in beta-amyloid peptide Abeta(1-28) leads to an inhibitor of Abeta(1-28) amyloidogenesis and cytotoxicity. Chem Biol 2003 0.86
58 MIF and CD74 - suitability as clinical biomarkers. Mini Rev Med Chem 2014 0.85
59 Gremlin-1 is an inhibitor of macrophage migration inhibitory factor and attenuates atherosclerotic plaque growth in ApoE-/- Mice. J Biol Chem 2013 0.84
60 What is the significance of perioperative release of macrophage migration inhibitory factor in cardiac surgery? Antioxid Redox Signal 2013 0.84
61 Assessment of macrophage migration inhibitory factor in humans: protocol for accurate and reproducible levels. Free Radic Biol Med 2013 0.84
62 Expression and function of macrophage migration inhibitory factor in the pathogenesis of UV-induced cutaneous nonmelanoma skin cancer. Photochem Photobiol 2012 0.83
63 Controlled intramyocardial release of engineered chemokines by biodegradable hydrogels as a treatment approach of myocardial infarction. J Cell Mol Med 2014 0.83
64 Interactions of T helper cells with fibroblast-like synoviocytes: up-regulation of matrix metalloproteinases by macrophage migration inhibitory factor from both Th1 and Th2 cells. Arthritis Rheum 2008 0.82
65 Carbon monoxide intoxication versus myocardial infarction: An easy diagnosis? Burns 2011 0.82
66 Macrophage migration inhibitory factor-A potential diagnostic tool in severe burn injuries? Burns 2009 0.82
67 Targeted intracellular accumulation of macrophage migration inhibitory factor in the reperfused heart mediates cardioprotection. Thromb Haemost 2015 0.81
68 Endothelial CSN5 impairs NF-κB activation and monocyte adhesion to endothelial cells and is highly expressed in human atherosclerotic lesions. Thromb Haemost 2013 0.81
69 Development of accessible peptidic tool compounds to study the phosphatase PTP1B in intact cells. ACS Chem Biol 2014 0.81
70 Blood levels of macrophage migration inhibitory factor after successful resuscitation from cardiac arrest. PLoS One 2012 0.81
71 Macrophage migration and function: from recruitment in vascular disease to redox regulation in the immune and neuroendocrine networks. Antioxid Redox Signal 2005 0.80
72 Levels of macrophage migration inhibitory factor and glucocorticoids in chronic wound patients and their potential interactions with impaired wound endothelial progenitor cell migration. Wound Repair Regen 2012 0.80
73 Macrophage migration inhibitory factor increases neuronal delayed rectifier K+ current. J Neurophysiol 2005 0.79
74 Macrophage migration inhibitory factor is a potential inducer of endothelial progenitor cell mobilization after flap operation. Surgery 2010 0.78
75 Endothelial progenitor cells--potential new avenues to improve neoangiogenesis and reendothelialization. Int Rev Cell Mol Biol 2013 0.77
76 Improved in vitro cultivation of endothelial progenitor cells as basis for dermal substitutes with enhanced angiogenic capabilities. Langenbecks Arch Surg 2011 0.76
77 The role of hypoxia-inducible factor-1α and vascular endothelial growth factor in late-phase preconditioning with xenon, isoflurane and levosimendan in rat cardiomyocytes. Interact Cardiovasc Thorac Surg 2013 0.75
78 The Effect of Antiseptics on Adipose-Derived Stem Cells. Plast Reconstr Surg 2017 0.75
79 Directed arginine deiminase evolution for efficient inhibition of arginine-auxotrophic melanomas. Appl Microbiol Biotechnol 2014 0.75