Published in Cell Signal on August 31, 2010
Role of macrophage migration inhibitory factor (MIF) in pollen-induced allergic conjunctivitis and pollen dermatitis in mice. PLoS One (2015) 1.39
Macrophage migration inhibitory factor and CD74 regulate macrophage chemotactic responses via MAPK and Rho GTPase. J Immunol (2011) 1.19
Cystic fibrosis sputum DNA has NETosis characteristics and neutrophil extracellular trap release is regulated by macrophage migration-inhibitory factor. J Innate Immun (2014) 1.06
Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular Perspectives. Front Immunol (2015) 1.05
D-dopachrome tautomerase (D-DT or MIF-2): doubling the MIF cytokine family. Cytokine (2012) 1.01
Steroid receptor coactivator 3 regulates autophagy in breast cancer cells through macrophage migration inhibitory factor. Cell Res (2012) 0.99
Indoleamine 2,3-dioxygenase-1 (IDO1) enhances survival and invasiveness of endometrial stromal cells via the activation of JNK signaling pathway. Int J Clin Exp Pathol (2013) 0.94
Arrest Functions of the MIF Ligand/Receptor Axes in Atherogenesis. Front Immunol (2013) 0.94
ELAVL1 modulates transcriptome-wide miRNA binding in murine macrophages. Cell Rep (2014) 0.92
Innate immunity and cell death in alcoholic liver disease: role of cytochrome P4502E1. Redox Biol (2014) 0.91
Role of macrophage migration inhibitory factor in the Th2 immune response to epicutaneous sensitization. J Clin Immunol (2011) 0.85
Role of macrophage migration inhibitory factor in the proliferation of smooth muscle cell in pulmonary hypertension. Mediators Inflamm (2012) 0.85
Overexpression of macrophage migration inhibitory factor in adenoid cystic carcinoma: correlation with enhanced metastatic potential. J Cancer Res Clin Oncol (2012) 0.85
Src homology-2 domain-containing protein tyrosine phosphatase (SHP) 2 and p38 regulate the expression of chemokine CXCL8 in human astrocytes. PLoS One (2012) 0.85
Macrophage migration inhibitory factor produced by the tumour stroma but not by tumour cells regulates angiogenesis in the B16-F10 melanoma model. Br J Cancer (2012) 0.84
Macrophage migration inhibitory factor receptor CD74 mediates alphavirus-induced arthritis and myositis in murine models of alphavirus infection. Arthritis Rheum (2013) 0.82
High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates. Proc Natl Acad Sci U S A (2016) 0.81
Role of macrophage migration inhibitory factor in age-related lung disease. Am J Physiol Lung Cell Mol Physiol (2015) 0.80
Differential roles of cardiac and leukocyte derived macrophage migration inhibitory factor in inflammatory responses and cardiac remodelling post myocardial infarction. J Mol Cell Cardiol (2014) 0.79
Attenuation of atherosclerotic lesions in diabetic apolipoprotein E-deficient mice using gene silencing of macrophage migration inhibitory factor. J Cell Mol Med (2015) 0.79
Macrophage migration inhibitory factor involvement in breast cancer (Review). Int J Oncol (2015) 0.78
CXCL5 signaling is a shared pathway of neuroinflammation and blood-brain barrier injury contributing to white matter injury in the immature brain. J Neuroinflammation (2016) 0.77
Macrophage migration inhibitory factor promotes resistance to glucocorticoid treatment in EAE. Neurol Neuroimmunol Neuroinflamm (2015) 0.77
Macrophage migration inhibitory factor promotes eosinophil accumulation and tissue remodeling in eosinophilic esophagitis. Mucosal Immunol (2015) 0.77
Macrophage migration inhibitory factor activates inflammatory responses of astrocytes through interaction with CD74 receptor. Oncotarget (2016) 0.76
Plasma Levels of Macrophage Migration Inhibitory Factor and d-Dopachrome Tautomerase Show a Highly Specific Profile in Early Life. Front Immunol (2017) 0.75
25 Years On: A Retrospective on Migration Inhibitory Factor in Tumor Angiogenesis. Mol Med (2015) 0.75
Natural Killer Cells: Angels and Devils for Immunotherapy. Int J Mol Sci (2017) 0.75
Mammalian MAP kinase signalling cascades. Nature (2001) 18.89
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The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med (2006) 10.99
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Macrophage migration inhibitory factor: a regulator of innate immunity. Nat Rev Immunol (2003) 5.85
MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia. Nature (1993) 5.60
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MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nat Med (2007) 5.28
MIF as a glucocorticoid-induced modulator of cytokine production. Nature (1995) 5.21
MIF signal transduction initiated by binding to CD74. J Exp Med (2003) 4.79
Protection from septic shock by neutralization of macrophage migration inhibitory factor. Nat Med (2000) 3.89
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature (2000) 3.81
CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity (2006) 3.38
Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response. Proc Natl Acad Sci U S A (2001) 3.29
Regulation of CXCR4 signaling. Biochim Biophys Acta (2006) 3.16
Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome. Nat Med (1997) 2.98
Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid action. J Biol Chem (1999) 2.60
Interleukin-1 (IL-1) pathway. Sci Signal (2010) 2.58
MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis. Nat Rev Drug Discov (2006) 2.30
The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting. Proc Natl Acad Sci U S A (2003) 2.29
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Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity. Oncogene (2007) 2.08
Macrophage migration inhibitory factor in cardiovascular disease. Circulation (2008) 1.91
c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges. Biochim Biophys Acta (2009) 1.82
CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer. Int J Cancer (2009) 1.79
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MAP kinase activation in macrophages. J Leukoc Biol (2001) 1.64
The isoform-specific functions of the c-Jun N-terminal Kinases (JNKs): differences revealed by gene targeting. Bioessays (2006) 1.63
Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter. FEBS Lett (2003) 1.59
A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett (2009) 1.54
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity. Cell Signal (2005) 1.53
Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion. J Clin Invest (2009) 1.48
IL-8 secreted in a macrophage migration-inhibitory factor- and CD74-dependent manner regulates B cell chronic lymphocytic leukemia survival. Proc Natl Acad Sci U S A (2007) 1.47
Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF). Semin Cancer Biol (2000) 1.38
A role for CXCL12 (SDF-1alpha) in the pathogenesis of multiple sclerosis: regulation of CXCL12 expression in astrocytes by soluble myelin basic protein. J Neuroimmunol (2006) 1.35
Bone marrow stromal cells and the upregulation of interleukin-8 production in human T-cell acute lymphoblastic leukemia through the CXCL12/CXCR4 axis and the NF-kappaB and JNK/AP-1 pathways. Haematologica (2008) 1.35
Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways. J Biol Chem (2001) 1.34
The Golgi-associated protein p115 mediates the secretion of macrophage migration inhibitory factor. J Immunol (2009) 1.25
Cooperative regulation of non-small cell lung carcinoma angiogenic potential by macrophage migration inhibitory factor and its homolog, D-dopachrome tautomerase. J Immunol (2008) 1.21
Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis. Arthritis Res Ther (2006) 1.19
Macrophage migration inhibitory factor induces MMP-9 expression in macrophages via the MEK-ERK MAP kinase pathway. J Interferon Cytokine Res (2007) 1.18
Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice. Circulation (2003) 1.17
The cytokine macrophage migration inhibitory factor reduces pro-oxidative stress-induced apoptosis. J Immunol (2003) 1.15
Helicobacter pylori CagA-dependent macrophage migration inhibitory factor produced by gastric epithelial cells binds to CD74 and stimulates procarcinogenic events. J Immunol (2006) 1.07
Chemokines and chemokine receptors in stem cell circulation. Front Biosci (2008) 1.04
Two murine homologues of the human chemokine receptor CXCR4 mediating stromal cell-derived factor 1alpha activation of Gi2 are differentially expressed in vivo. Eur J Immunol (1997) 1.03
Roles for phosphoinositide 3-kinases, Bruton's tyrosine kinase, and Jun kinases in B lymphocyte chemotaxis and homing. Eur J Immunol (2006) 1.02
Ultraviolet A-induced production of matrix metalloproteinase-1 is mediated by macrophage migration inhibitory factor (MIF) in human dermal fibroblasts. J Biol Chem (2003) 0.99
A 16-residue peptide fragment of macrophage migration inhibitory factor, MIF-(50-65), exhibits redox activity and has MIF-like biological functions. J Biol Chem (2003) 0.99
Dissection of the enzymatic and immunologic functions of macrophage migration inhibitory factor. Full immunologic activity of N-terminally truncated mutants. Eur J Biochem (2000) 0.99
CXCR4 chemokine receptor engagement modifies integrin dependent adhesion of renal carcinoma cells. Exp Cell Res (2007) 0.96
Macrophage migration inhibitory factor within the alveolar spaces induces changes in the heart during late experimental sepsis. Shock (2005) 0.94
Structure activity studies of the cytokine macrophage migration inhibitory factor (MIF) reveal a critical role for its carboxy terminus. FEBS Lett (1997) 0.93
Macrophage migration inhibitory factor induces cardiomyocyte apoptosis. Biochem Biophys Res Commun (2008) 0.90
Differential subcellular localization of two dopamine D2 receptor isoforms in transfected NG108-15 cells. J Neurochem (2003) 0.88
The anti-cancer compound Nordy inhibits CXCR4-mediated production of IL-8 and VEGF by malignant human glioma cells. J Neurooncol (2007) 0.86
ATF-1 mediates protease-activated receptor-1 but not receptor tyrosine kinase-induced DNA synthesis in vascular smooth muscle cells. J Biol Chem (2002) 0.86
CXCR4 down-regulation by small interfering RNA inhibits invasion and tubule formation of human retinal microvascular endothelial cells. Biochem Biophys Res Commun (2007) 0.85
Endothelin-1 activates c-Jun NH2-terminal kinase in mesangial cells. Kidney Int (1997) 0.79
Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med (2005) 8.49
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nat Med (2007) 5.28
MIF signal transduction initiated by binding to CD74. J Exp Med (2003) 4.79
Investigations on DNA intercalation and surface binding by SYBR Green I, its structure determination and methodological implications. Nucleic Acids Res (2004) 3.45
CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity (2006) 3.38
Circulating fibrocytes: collagen-secreting cells of the peripheral blood. Int J Biochem Cell Biol (2004) 3.34
Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response. Proc Natl Acad Sci U S A (2001) 3.29
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature (2008) 2.96
MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis. Nat Rev Drug Discov (2006) 2.30
Fibrocytes: emerging effector cells in chronic inflammation. Nat Rev Immunol (2011) 2.26
Macrophage migration inhibitory factor (MIF): mechanisms of action and role in disease. Microbes Infect (2002) 2.10
Inhibition of macrophage migration inhibitory factor or its receptor (CD74) attenuates growth and invasion of DU-145 prostate cancer cells. J Immunol (2006) 2.09
Macrophage migration inhibitory factor promotes intestinal tumorigenesis. Gastroenterology (2005) 2.05
Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction. J Am Coll Cardiol (2011) 1.95
Macrophage migration inhibitory factor in cardiovascular disease. Circulation (2008) 1.91
A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice. J Immunol (2010) 1.91
Fibrocytes in health and disease. Exp Hematol (2010) 1.90
Macrophage migration inhibitory factor (MIF) exerts antifibrotic effects in experimental liver fibrosis via CD74. Proc Natl Acad Sci U S A (2011) 1.85
High expression of inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (iPFK-2; PFKFB3) in human cancers. Cancer Res (2002) 1.84
The role of circulating fibrocytes in fibrosis. Curr Rheumatol Rep (2006) 1.78
The macrophage migration inhibitory factor-glucocorticoid dyad: regulation of inflammation and immunity. Mol Endocrinol (2007) 1.73
Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex. J Biol Chem (2007) 1.71
A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia. J Exp Med (2006) 1.61
Regulated secretion of macrophage migration inhibitory factor is mediated by a non-classical pathway involving an ABC transporter. FEBS Lett (2003) 1.59
Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion. J Clin Invest (2007) 1.57
Advanced glycation endproducts in nondiabetic patients with obstructive sleep apnea. Sleep (2006) 1.57
Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart. Circulation (2010) 1.56
Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis. Circulation (2002) 1.56
Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites. Proc Natl Acad Sci U S A (2002) 1.55
Cytokines in sepsis: potent immunoregulators and potential therapeutic targets--an updated view. Mediators Inflamm (2013) 1.54
A functional heteromeric MIF receptor formed by CD74 and CXCR4. FEBS Lett (2009) 1.54
Macrophage migration inhibitory factor is released from pituitary folliculo-stellate-like cells by endotoxin and dexamethasone and attenuates the steroid-induced inhibition of interleukin 6 release. Endocrinology (2004) 1.54
Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise. Proc Natl Acad Sci U S A (2012) 1.53
Rapid and transient activation of the ERK MAPK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on JAB1/CSN5 and Src kinase activity. Cell Signal (2005) 1.53
The anemia of malaria infection: role of inflammatory cytokines. Curr Hematol Rep (2004) 1.53
A novel, macrophage migration inhibitory factor suicide substrate inhibits motility and growth of lung cancer cells. Cancer Res (2008) 1.49
MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease. Circ Res (2009) 1.49
Macrophage migration inhibitory factor (MIF): a promising biomarker. Drug News Perspect (2010) 1.48
Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid. J Immunol (2009) 1.48
Endotoxin-induced myocardial dysfunction: effects of macrophage migration inhibitory factor neutralization. Circ Res (2005) 1.48
Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion. J Clin Invest (2009) 1.48
IL-8 secreted in a macrophage migration-inhibitory factor- and CD74-dependent manner regulates B cell chronic lymphocytic leukemia survival. Proc Natl Acad Sci U S A (2007) 1.47
A tautomerase-null macrophage migration-inhibitory factor (MIF) gene knock-in mouse model reveals that protein interactions and not enzymatic activity mediate MIF-dependent growth regulation. Mol Cell Biol (2009) 1.43
Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment. Proc Natl Acad Sci U S A (2008) 1.41
Discovery of human macrophage migration inhibitory factor (MIF)-CD74 antagonists via virtual screening. J Med Chem (2009) 1.39
Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly. Aging Cell (2011) 1.39
Macrophage migration inhibitory factor. Crit Care Med (2002) 1.36
Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma. Arthritis Rheum (2006) 1.35
CD44 is a negative regulator of acute pulmonary inflammation and lipopolysaccharide-TLR signaling in mouse macrophages. J Immunol (2007) 1.32
Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF). Atherosclerosis (2006) 1.31
Pigment epithelium-derived factor inhibits advanced glycation end product-induced retinal vascular hyperpermeability by blocking reactive oxygen species-mediated vascular endothelial growth factor expression. J Biol Chem (2006) 1.30
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF). Proc Natl Acad Sci U S A (2011) 1.29
Macrophage migration inhibitory factor. Expert Opin Ther Targets (2003) 1.28
Macrophage migration inhibitory factor and autism spectrum disorders. Pediatrics (2008) 1.27
Control of fibroblast-like synoviocyte proliferation by macrophage migration inhibitory factor. Arthritis Rheum (2003) 1.26
Dual role of macrophage migration inhibitory factor (MIF) in human breast cancer. BMC Cancer (2009) 1.26
Phosphorylation of the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase/PFKFB3 family of glycolytic regulators in human cancer. Clin Cancer Res (2005) 1.26
Macrophage migration inhibitory factor deficiency impairs atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation (2004) 1.25
The Golgi-associated protein p115 mediates the secretion of macrophage migration inhibitory factor. J Immunol (2009) 1.25
Inhibition of MIF bioactivity by rational design of pharmacological inhibitors of MIF tautomerase activity. J Med Chem (2002) 1.25
Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host. J Infect Dis (2007) 1.25
Macrophage migration inhibitory factor regulates neutrophil chemotactic responses in inflammatory arthritis in mice. Arthritis Rheum (2011) 1.24
Regulation of p53 by macrophage migration inhibitory factor in inflammatory arthritis. Arthritis Rheum (2003) 1.24