Published in Mol Pharmacol on September 08, 2005
The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site. Mol Cell (2008) 4.29
Single-molecule dynamics of gating in a neurotransmitter transporter homologue. Nature (2010) 2.41
Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation. Proc Natl Acad Sci U S A (2009) 2.25
Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters. Nat Struct Mol Biol (2010) 2.20
Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue. Nature (2011) 2.18
Nonvesicular inhibitory neurotransmission via reversal of the GABA transporter GAT-1. Neuron (2007) 1.57
Structure and function of sodium-coupled GABA and glutamate transporters. J Membr Biol (2007) 1.23
GABA metabolism and transport: effects on synaptic efficacy. Neural Plast (2012) 0.94
A glutamine residue conserved in the neurotransmitter:sodium:symporters is essential for the interaction of chloride with the GABA transporter GAT-1. J Biol Chem (2010) 0.91
Functional expression of γ-amino butyric acid transporter 2 in human and guinea pig airway epithelium and smooth muscle. Am J Respir Cell Mol Biol (2010) 0.87
To be, or not to be two sites: that is the question about LeuT substrate binding. J Gen Physiol (2011) 0.86
Turnover rate of the gamma-aminobutyric acid transporter GAT1. J Membr Biol (2007) 0.86
Structure, function, and plasticity of GABA transporters. Front Cell Neurosci (2014) 0.86
Cl⁻ homeodynamics in gap junction-coupled astrocytic networks on activation of GABAergic synapses. J Physiol (2013) 0.81
Inhibition of Activity of GABA Transporter GAT1 by δ-Opioid Receptor. Evid Based Complement Alternat Med (2012) 0.79
Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation. Neurochem Int (2014) 0.79
Functional consequences of sulfhydryl modification of the γ-aminobutyric acid transporter 1 at a single solvent-exposed cysteine residue. J Membr Biol (2012) 0.77
Inhibitors of the gamma-aminobutyric acid transporter 1 (GAT1) do not reveal a channel mode of conduction. Neurochem Int (2009) 0.77
Transporter-mediated GABA responses in horizontal and bipolar cells of zebrafish retina. Vis Neurosci (2008) 0.76
Diabetes Impairs Wnt3 Protein-induced Neurogenesis in Olfactory Bulbs via Glutamate Transporter 1 Inhibition. J Biol Chem (2016) 0.75
The effects of volatile anesthetics on the extracellular accumulation of [(3)H]GABA in rat brain cortical slices. Cell Mol Neurobiol (2013) 0.75
PEDV ORF3 encodes an ion channel protein and regulates virus production. FEBS Lett (2012) 1.29
Severe acute respiratory syndrome-associated coronavirus 3a protein forms an ion channel and modulates virus release. Proc Natl Acad Sci U S A (2006) 1.07
Na,K-ATPase mutations in familial hemiplegic migraine lead to functional inactivation. Biochim Biophys Acta (2005) 1.01
Dissociations between reaction times and temporal order judgments: a diffusion model approach. J Exp Psychol Hum Percept Perform (2006) 0.97
Fast degradation of the auxiliary subunit of Na+/K+-ATPase in the plasma membrane of HeLa cells. J Cell Sci (2008) 0.93
4'-phosphopantetheine biosynthesis in Archaea. J Biol Chem (2005) 0.89
Stimulation of Xenopus oocyte Na(+),K(+)ATPase by the serum and glucocorticoid-dependent kinase sgk1. Pflugers Arch (2002) 0.86
An untapped bacterial cellulolytic community enriched from coastal marine sediment under anaerobic and thermophilic conditions. FEMS Microbiol Lett (2012) 0.85
ATP release from mast cells by physical stimulation: a putative early step in activation of acupuncture points. Evid Based Complement Alternat Med (2013) 0.85
Stimulation of TRPV1 by Green Laser Light. Evid Based Complement Alternat Med (2012) 0.85
Single-channel properties of a stretch-sensitive chloride channel in the human mast cell line HMC-1. Eur Biophys J (2009) 0.82
Increased pericardial adipose tissue is correlated with atrial fibrillation and left atrial dilatation. Clin Res Cardiol (2013) 0.81
Regulation of the cardiovascular function by CO2 laser stimulation in anesthetized rats. Lasers Med Sci (2011) 0.81
DIDS blocks a chloride-dependent current that is mediated by the 2B protein of enterovirus 71. Cell Res (2011) 0.80
Why jackknifing yields good latency estimates. Psychophysiology (2009) 0.80
Functional role of the N-terminus of Na(+),K(+)-ATPase alpha-subunit as an inactivation gate of palytoxin-induced pump channel. Biochim Biophys Acta (2003) 0.79
Inhibition of Activity of GABA Transporter GAT1 by δ-Opioid Receptor. Evid Based Complement Alternat Med (2012) 0.79
Expression and transport function of the glutamate transporter EAAC1 in Xenopus oocytes is regulated by syntaxin 1A. J Neurosci Res (2005) 0.78
Interactions of Na+,K+-ATPase and co-expressed delta-opioid receptor. Neurosci Res (2009) 0.78
Regulation of the glutamate transporter EAAC1 by expression and activation of delta-opioid receptor. Eur J Neurosci (2006) 0.78
Emodin inhibits current through SARS-associated coronavirus 3a protein. Antiviral Res (2011) 0.77
Involvement in K+ access of Leu318 at the extracellular domain flanking M3 and M4 of the Na+,K+-ATPase alpha-subunit. Biochem Biophys Res Commun (2005) 0.77
[Skin slice used as a model for investigating acupuncture effects]. Zhen Ci Yan Jiu (2009) 0.77
Epigallocatechin-3-gallate is an inhibitor of Na+, K(+)-ATPase by favoring the E1 conformation. Biochem Pharmacol (2009) 0.76
Different functional roles of arginine residues 39 and 61 and tyrosine residue 98 in transport and channel mode of the glutamate transporter EAAC1. Biochim Biophys Acta (2004) 0.76
Selective suppression of hippocampal region hyperexcitability related to seizure susceptibility in epileptic El mice by the GABA-transporter inhibitor tiagabine. Brain Res (2002) 0.75
Effects of alpha-asarone on the glutamate transporter EAAC1 in Xenopus oocytes. Planta Med (2009) 0.75
[Electroacupuncture alleviates complete Freund's adjuvant peripheral chronic inflammatory pain in mice]. Zhongguo Zhen Jiu (2008) 0.75
Synthesis and structure of K+ [iPrN=C=P]-, a 1-aza-3lambda3-phospha-3-allenide. Inorg Chem (2005) 0.75