PubRank

Carole A Bewley

Author PubWeight™ 73.13‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature 2011 7.20
2 Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4. Science 2007 4.35
3 Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops. Proc Natl Acad Sci U S A 2012 2.69
4 Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16. Nat Struct Mol Biol 2013 2.42
5 Mirabamides A-D, depsipeptides from the sponge Siliquariaspongia mirabilis that inhibit HIV-1 fusion. J Nat Prod 2007 1.72
6 Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion. J Biol Chem 2003 1.34
7 Largamides A-H, unusual cyclic peptides from the marine cyanobacterium Oscillatoria sp. J Org Chem 2006 1.31
8 Sequestering of the prehairpin intermediate of gp41 by peptide N36Mut(e,g) potentiates the human immunodeficiency virus type 1 neutralizing activity of monoclonal antibodies directed against the N-terminal helical repeat of gp41. J Virol 2008 1.21
9 Conformational changes in HIV-1 gp41 in the course of HIV-1 envelope glycoprotein-mediated fusion and inactivation. Biochemistry 2005 1.20
10 Characterization and HIV-1 fusion inhibitory properties of monoclonal Fabs obtained from a human non-immune phage library selected against diverse epitopes of the ectodomain of HIV-1 gp41. J Mol Biol 2005 1.15
11 Using conjoined rigid body/torsion angle simulated annealing to determine the relative orientation of covalently linked protein domains from dipolar couplings. J Magn Reson 2002 1.15
12 Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41. PLoS Pathog 2010 1.14
13 Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics. Virology 2008 1.11
14 Crystal structures of the HIV-1 inhibitory cyanobacterial protein MVL free and bound to Man3GlcNAc2: structural basis for specificity and high-affinity binding to the core pentasaccharide from n-linked oligomannoside. J Biol Chem 2005 1.10
15 Inhibition and kinetics of mycobacterium tuberculosis and mycobacterium smegmatis mycothiol-S-conjugate amidase by natural product inhibitors. Bioorg Med Chem 2003 1.08
16 Mirabamides E-H, HIV-inhibitory depsipeptides from the sponge Stelletta clavosa. J Nat Prod 2011 1.06
17 Celebesides A-C and theopapuamides B-D, depsipeptides from an Indonesian sponge that inhibit HIV-1 entry. J Org Chem 2009 1.05
18 A monoclonal Fab derived from a human nonimmune phage library reveals a new epitope on gp41 and neutralizes diverse human immunodeficiency virus type 1 strains. J Virol 2007 1.05
19 Structural basis for norovirus inhibition and fucose mimicry by citrate. J Virol 2011 1.05
20 Crambescidin 826 and dehydrocrambine A: new polycyclic guanidine alkaloids from the marine sponge Monanchora sp. that inhibit HIV-1 fusion. J Nat Prod 2003 1.02
21 Chrysophaentins A-H, antibacterial bisdiarylbutene macrocycles that inhibit the bacterial cell division protein FtsZ. J Am Chem Soc 2010 1.01
22 Batzelline D and isobatzelline E from the indopacific sponge Zyzzya fuliginosa. J Nat Prod 2002 1.00
23 Differential inhibition of HIV-1 and SIV envelope-mediated cell fusion by C34 peptides derived from the C-terminal heptad repeat of gp41 from diverse strains of HIV-1, HIV-2, and SIV. J Med Chem 2005 0.99
24 Natural products, small molecules, and genetics in tuberculosis drug development. J Med Chem 2008 0.98
25 Temperature-dependent intermediates in HIV-1 envelope glycoprotein-mediated fusion revealed by inhibitors that target N- and C-terminal helical regions of HIV-1 gp41. Biochemistry 2004 0.96
26 Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry. Bioorg Med Chem 2008 0.96
27 Bromotyrosine-derived natural and synthetic products as inhibitors of mycothiol-S-conjugate amidase. Bioorg Med Chem Lett 2002 0.96
28 Solution structure of the monovalent lectin microvirin in complex with Man(alpha)(1-2)Man provides a basis for anti-HIV activity with low toxicity. J Biol Chem 2011 0.96
29 Engineering an obligate domain-swapped dimer of cyanovirin-N with enhanced anti-HIV activity. J Am Chem Soc 2002 0.96
30 Potent inhibition of HIV-1 fusion by cyanovirin-N requires only a single high affinity carbohydrate binding site: characterization of low affinity carbohydrate binding site knockout mutants. J Mol Biol 2002 0.96
31 Mutremdamide A and koshikamides C-H, peptide inhibitors of HIV-1 entry from different Theonella species. J Org Chem 2010 0.95
32 Shortcut to mycothiol analogues. Org Lett 2002 0.95
33 Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry. ACS Chem Biol 2011 0.94
34 Synthesis of natural product-inspired inhibitors of Mycobacterium tuberculosis mycothiol-associated enzymes: the first inhibitors of GlcNAc-Ins deacetylase. J Med Chem 2007 0.93
35 Research achievement award--D. John Faulkner. J Nat Prod 2004 0.91
36 A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption. Biochemistry 2013 0.90
37 Peptides from second extracellular loop of C-C chemokine receptor type 5 (CCR5) inhibit diverse strains of HIV-1. J Biol Chem 2012 0.89
38 Motualevic acids A-F, antimicrobial acids from the sponge Siliquariaspongia sp. Org Lett 2009 0.89
39 Synergistic inhibition of HIV-1 envelope-mediated membrane fusion by inhibitors targeting the N and C-terminal heptad repeats of gp41. J Mol Biol 2006 0.88
40 Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening. J Biomol Screen 2009 0.88
41 Mirabalin, [corrected] an antitumor macrolide lactam from the marine sponge Siliquariaspongia mirabilis. J Nat Prod 2008 0.87
42 Synthetic macrolides that inhibit breast cancer cell migration in vitro. J Am Chem Soc 2007 0.87
43 Paltolides A--C, anabaenopeptin-type peptides from the palau sponge Theonella swinhoei. J Nat Prod 2010 0.86
44 Affinity maturation by targeted diversification of the CDR-H2 loop of a monoclonal Fab derived from a synthetic naïve human antibody library and directed against the internal trimeric coiled-coil of gp41 yields a set of Fabs with improved HIV-1 neutralization potency and breadth. Virology 2009 0.86
45 HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth. Expert Opin Ther Targets 2015 0.86
46 Cloning, expression and rapid purification of active recombinant mycothiol ligase as B1 immunoglobulin binding domain of streptococcal protein G, glutathione-S-transferase and maltose binding protein fusion proteins in Mycobacterium smegmatis. Protein Expr Purif 2006 0.85
47 Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria. Bioorg Med Chem 2013 0.83
48 Total synthesis and proof of structure of mycothiol bimane. J Am Chem Soc 2002 0.82
49 Geographic variability and anti-staphylococcal activity of the chrysophaentins and their synthetic fragments. Mar Drugs 2012 0.81
50 Synthesis of 1-D- and 1-L-myo-inosityl 2-N-acetamido-2-deoxy-alpha-D-glucopyranoside establishes substrate specificity of the Mycobacterium tuberculosis enzyme AcGI deacetylase. Bioorg Med Chem 2003 0.79
51 Design and synthesis of substrate-mimic inhibitors of mycothiol-S-conjugate amidase from Mycobacterium tuberculosis. Bioorg Med Chem Lett 2006 0.79
52 Unprecedented glycosidase activity at a lectin carbohydrate-binding site exemplified by the cyanobacterial lectin MVL. J Am Chem Soc 2009 0.78
53 Solution conformations of mycothiol bimane, 1-D-GlcNAc-alpha-(1 --> 1)-D-myo-Ins and 1-D-GlcNAc-alpha-(1 --> 1)-L-myo-Ins. J Org Chem 2003 0.78
54 Discovery and synthesis of namalide reveals a new anabaenopeptin scaffold and peptidase inhibitor. J Med Chem 2012 0.77
55 Characterization and carbohydrate specificity of pradimicin S. J Am Chem Soc 2012 0.77
56 Synthesis of a bromotyrosine-derived natural product inhibitor of mycothiol-S-conjugate amidase. Bioorg Med Chem Lett 2004 0.77
57 Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy. J Biomol NMR 2011 0.77
58 Mammalian expression of isotopically labeled proteins for NMR spectroscopy. Adv Exp Med Biol 2012 0.76
59 Glycopeptide mimetics recapitulate high-mannose-type oligosaccharide binding and function. Angew Chem Int Ed Engl 2015 0.76
60 Susceptibility and mode of binding of the Mycobacterium tuberculosis cysteinyl transferase mycothiol ligase to tRNA synthetase inhibitors. Bioorg Med Chem Lett 2011 0.76
61 Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosis. J Immunol 2012 0.76
62 Correction: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability. PLoS Pathog 2016 0.75
63 Motualevic acids and analogs: synthesis and antimicrobial structure-activity relationships. Bioorg Med Chem Lett 2010 0.75
64 Synthesis of novel cyclic NGR/RGD peptide analogs via on resin click chemistry. Bioorg Med Chem Lett 2010 0.75
65 A model for cell-surface-exposed carbohydrate moieties suitable for structural studies by NMR spectroscopy. Chembiochem 2006 0.75
66 Metabolism and Bioactivation of Fluorochloridone, a Novel Selective Herbicide, in Vivo and in Vitro. Environ Sci Technol 2016 0.75
67 John W. Daly (1933-2008). J Nat Prod 2010 0.75