Published in BMC Mol Biol on September 12, 2005
Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response. Mol Cell Proteomics (2010) 1.81
Regulation of protein synthesis by ionizing radiation. Mol Cell Biol (2009) 1.52
TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1. BMC Mol Biol (2009) 1.09
Mitotic crisis: the unmasking of a novel role for RPA. Cell Cycle (2009) 0.96
Chromatin disassembly and reassembly during DNA repair. Mutat Res (2007) 0.95
Recombinant AAV9-TLK1B administration ameliorates fractionated radiation-induced xerostomia. Hum Gene Ther (2013) 0.93
TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1. BMC Mol Biol (2006) 0.89
Tousled-like kinases modulate reactivation of gammaherpesviruses from latency. Cell Host Microbe (2013) 0.89
Tousled kinase activator, gallic acid, promotes homologous recombinational repair and suppresses radiation cytotoxicity in salivary gland cells. Free Radic Biol Med (2016) 0.85
Tousled kinase TLK1B mediates chromatin assembly in conjunction with Asf1 regardless of its kinase activity. BMC Res Notes (2010) 0.81
The Tousled-Like Kinases as Guardians of Genome Integrity. ISRN Mol Biol (2012) 0.81
Tousled kinase TLK1B counteracts the effect of Asf1 in inhibition of histone H3-H4 tetramer formation. BMC Res Notes (2009) 0.81
Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy. Genes Cancer (2013) 0.79
TLK1B mediated phosphorylation of Rad9 regulates its nuclear/cytoplasmic localization and cell cycle checkpoint. BMC Mol Biol (2016) 0.75
Differential requirements for Tousled-like kinases 1 and 2 in mammalian development. Cell Death Differ (2017) 0.75
Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol (1967) 106.91
Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis. Proc Natl Acad Sci U S A (1975) 8.75
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol (2003) 8.55
Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell (2000) 6.81
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat Cell Biol (2002) 5.85
eIF-4E expression and its role in malignancies and metastases. Oncogene (2004) 5.10
Phosphorylation of histone H3 is required for proper chromosome condensation and segregation. Cell (1999) 4.83
INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair. Cell (2004) 4.20
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A. Cancer Cell (2003) 3.58
Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J Biol Chem (2003) 3.34
Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. EMBO Rep (2002) 2.40
Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts. J Biol Chem (1999) 2.24
Asf1 links Rad53 to control of chromatin assembly. Genes Dev (2001) 2.16
Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage. EMBO Rep (2003) 1.96
Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases. Curr Biol (2001) 1.90
Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint. EMBO J (2003) 1.67
Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans. Cell (2000) 1.66
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors. J Cell Physiol (2005) 1.66
Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication. EMBO J (1999) 1.65
A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression. Cell (2001) 1.58
Core histone N-termini play an essential role in mitotic chromosome condensation. EMBO J (2000) 1.49
TOUSLED participates in apical tissue formation during gynoecium development in Arabidopsis. Plant Cell (1997) 1.43
A translationally regulated Tousled kinase phosphorylates histone H3 and confers radioresistance when overexpressed. Oncogene (2001) 1.40
Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1. Oncogene (2003) 1.33
Myeloid leukemias have increased activity of the nonhomologous end-joining pathway and concomitant DNA misrepair that is dependent on the Ku70/86 heterodimer. Cancer Res (2002) 1.30
Artemis links ATM to double strand break rejoining. Cell Cycle (2005) 1.30
Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions. Genes Dev (2003) 1.27
Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1. BMC Mol Biol (2004) 1.15
The C. elegans Tousled-like kinase contributes to chromosome segregation as a substrate and regulator of the Aurora B kinase. Curr Biol (2005) 1.10
TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators. Plant Physiol (2004) 1.07
A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells. BMC Cell Biol (2003) 1.05
Hyperacetylation and differential deacetylation of histones H4 and H3 define two distinct classes of acetylated SV40 chromosomes early in infection. Virology (2004) 0.86
TLK1B is elevated with eIF4E overexpression in breast cancer. J Surg Res (2004) 0.85
A novel BK virus-based episomal vector for expression of foreign genes in mammalian cells. Nucleic Acids Res (1991) 0.81
Purification and identification of a protein kinase activity modulated by ionizing radiation. Biochem Biophys Res Commun (2004) 0.80
Histone H1 and H3 dephosphorylation are differentially regulated by radiation-induced signal transduction pathways. Cancer Res (2000) 0.78
Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways. Blood (2010) 1.92
Post-transcriptional regulation of the androgen receptor by Mammalian target of rapamycin. Cancer Res (2005) 1.31
Tousled homolog, TLK1, binds and phosphorylates Rad9; TLK1 acts as a molecular chaperone in DNA repair. DNA Repair (Amst) (2008) 1.21
Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1. BMC Mol Biol (2004) 1.15
TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1. BMC Mol Biol (2009) 1.09
A dominant negative mutant of TLK1 causes chromosome missegregation and aneuploidy in normal breast epithelial cells. BMC Cell Biol (2003) 1.05
Heterogeneous nuclear ribonucleoprotein K is a novel regulator of androgen receptor translation. Cancer Res (2009) 1.02
Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer. J Exp Clin Cancer Res (2009) 0.98
TAT-mediated delivery of Tousled protein to salivary glands protects against radiation-induced hypofunction. Int J Radiat Oncol Biol Phys (2012) 0.91
TLK1B promotes repair of UV-damaged DNA through chromatin remodeling by Asf1. BMC Mol Biol (2006) 0.89
Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy. Bioorg Med Chem Lett (2011) 0.87
Coordinate transcriptional and translational repression of p53 by TGF-β1 impairs the stress response. Mol Cell (2013) 0.87
Selective killing of cancer cells based on translational control of a suicide gene. Cancer Gene Ther (2002) 0.86
TLK1B is elevated with eIF4E overexpression in breast cancer. J Surg Res (2004) 0.85
The expression of Tousled kinases in CaP cell lines and its relation to radiation response and DSB repair. Prostate (2011) 0.84
A cancer gene therapy approach through translational control of a suicide gene. Cancer Gene Ther (2002) 0.83
Up-regulation of TLK1B by eIF4E overexpression predicts cancer recurrence in irradiated patients with breast cancer. Surgery (2006) 0.81
Specific and nontoxic silencing in mammalian cells with expressed long dsRNAs. Nucleic Acids Res (2006) 0.81
Ctla-4 blockade plus adoptive T-cell transfer promotes optimal melanoma immunity in mice. J Immunother (2015) 0.80
Effectiveness of pulse-oximetry in addition to routine neonatal examination in detection of congenital heart disease in asymptomatic newborns. J Matern Fetal Neonatal Med (2014) 0.80
Phenothiazine Inhibitors of TLKs Affect Double-Strand Break Repair and DNA Damage Response Recovery and Potentiate Tumor Killing with Radiomimetic Therapy. Genes Cancer (2013) 0.79
p53 Interacts with RNA polymerase II through its core domain and impairs Pol II processivity in vivo. PLoS One (2011) 0.79
Nucleosome resection at a double-strand break during Non-Homologous Ends Joining in mammalian cells - implications from repressive chromatin organization and the role of ARTEMIS. BMC Res Notes (2011) 0.78
Translational upregulation of yes accompanies eIF4E-mediated oncogenic transformation. Int J Oncol (2003) 0.78
Synthesis and evaluation of quinazolinone derivatives as inhibitors of NF-kappaB, AP-1 mediated transcription and eIF-4E mediated translational activation: inhibitors of multi-pathways involve in cancer. Eur J Med Chem (2010) 0.77
A novel suicide gene therapy targeting the overexpression of eukaryotic initiation factor 4E improves survival in a rat peritoneal carcinomatosis model. Surgery (2007) 0.76
An object-based coding scheme for frontal surface of defective fluted ingot. ISA Trans (2006) 0.75
A novel shape-based coding-decoding technique for an industrial visual inspection system. ISA Trans (2004) 0.75