Published in Mol Cell on September 16, 2005
One step at a time: endoplasmic reticulum-associated degradation. Nat Rev Mol Cell Biol (2008) 8.68
OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD. Nat Cell Biol (2008) 4.54
Diversity of degradation signals in the ubiquitin-proteasome system. Nat Rev Mol Cell Biol (2008) 4.42
The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum. Traffic (2008) 3.07
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p. Cell (2010) 2.33
SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER. J Cell Biol (2006) 2.13
Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation. Semin Cell Dev Biol (2007) 2.13
Inhibition of p97-dependent protein degradation by Eeyarestatin I. J Biol Chem (2008) 2.07
Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum. J Cell Biol (2009) 1.93
Defining the glycan destruction signal for endoplasmic reticulum-associated degradation. Mol Cell (2008) 1.86
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP. J Biol Chem (2008) 1.77
Quality control: ER-associated degradation: protein quality control and beyond. J Cell Biol (2014) 1.75
The evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation. Proc Natl Acad Sci U S A (2007) 1.57
Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation. Mol Biol Cell (2007) 1.49
Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans. J Biol Chem (2009) 1.47
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Mol Biol Cell (2008) 1.44
GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum. Biochim Biophys Acta (2011) 1.42
A dual task for the Xbp1-responsive OS-9 variants in the mammalian endoplasmic reticulum: inhibiting secretion of misfolded protein conformers and enhancing their disposal. J Biol Chem (2008) 1.38
Automated identification of pathways from quantitative genetic interaction data. Mol Syst Biol (2010) 1.37
Architecture and biosynthesis of the Saccharomyces cerevisiae cell wall. Genetics (2012) 1.33
N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control. Curr Opin Struct Biol (2006) 1.30
GRP94 in ER quality control and stress responses. Semin Cell Dev Biol (2010) 1.29
The endoplasmic reticulum-associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones. Mol Biol Cell (2010) 1.17
Free oligosaccharides to monitor glycoprotein endoplasmic reticulum-associated degradation in Saccharomyces cerevisiae. J Biol Chem (2010) 1.14
Endoplasmic reticulum-associated degradation of glycoproteins in plants. Front Plant Sci (2012) 1.11
Strategies for carbohydrate recognition by the mannose 6-phosphate receptors. Glycobiology (2008) 1.11
Proteostasis regulation at the endoplasmic reticulum: a new perturbation site for targeted cancer therapy. Cell Res (2011) 1.07
Free N-linked oligosaccharide chains: formation and degradation. Glycoconj J (2006) 1.05
Intrinsic conformational determinants signal protein misfolding to the Hrd1/Htm1 endoplasmic reticulum-associated degradation system. Mol Biol Cell (2009) 1.05
Glycosylation-directed quality control of protein folding. Nat Rev Mol Cell Biol (2015) 1.04
Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase. J Cell Biol (2012) 1.03
Modularity of the Hrd1 ERAD complex underlies its diverse client range. J Cell Biol (2010) 1.02
Lectin chaperones help direct the maturation of glycoproteins in the endoplasmic reticulum. Biochim Biophys Acta (2009) 0.99
Roles of protein-disulfide isomerase-mediated disulfide bond formation of yeast Mnl1p in endoplasmic reticulum-associated degradation. J Biol Chem (2009) 0.97
Unraveling the function of Arabidopsis thaliana OS9 in the endoplasmic reticulum-associated degradation of glycoproteins. Plant Mol Biol (2012) 0.95
The endoplasmic reticulum-associated degradation pathways of budding yeast. Cold Spring Harb Perspect Biol (2012) 0.95
Yos9p assists in the degradation of certain nonglycosylated proteins from the endoplasmic reticulum. Mol Biol Cell (2011) 0.93
The Arabidopsis homolog of the mammalian OS-9 protein plays a key role in the endoplasmic reticulum-associated degradation of misfolded receptor-like kinases. Mol Plant (2012) 0.93
Ubiquitin-dependent protein degradation at the yeast endoplasmic reticulum and nuclear envelope. Crit Rev Biochem Mol Biol (2014) 0.92
Sorting things out through endoplasmic reticulum quality control. Mol Membr Biol (2010) 0.91
The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channel. J Biol Chem (2013) 0.89
Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking. FEBS Lett (2011) 0.88
Selective destruction of abnormal proteins by ubiquitin-mediated protein quality control degradation. Semin Cell Dev Biol (2012) 0.88
A novel role for Gtb1p in glucose trimming of N-linked glycans. Glycobiology (2009) 0.87
Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation. Mol Biol Cell (2012) 0.87
The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p. FEBS Lett (2008) 0.87
Protein quality control: the who's who, the where's and therapeutic escapes. Histochem Cell Biol (2007) 0.85
OS-9 facilitates turnover of nonnative GRP94 marked by hyperglycosylation. Mol Biol Cell (2014) 0.85
Cytosolic entry of Shiga-like toxin a chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p. PLoS One (2012) 0.84
A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER-associated degradation. Mol Biol Cell (2013) 0.83
Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex. J Biol Chem (2012) 0.82
Cell biology of the endoplasmic reticulum and the Golgi apparatus through proteomics. Cold Spring Harb Perspect Biol (2013) 0.82
Proteomic analysis of solid pseudopapillary tumor of the pancreas reveals dysfunction of the endoplasmic reticulum protein processing pathway. Mol Cell Proteomics (2014) 0.81
ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase. Histochem Cell Biol (2014) 0.81
Recent technical developments in the study of ER-associated degradation. Curr Opin Cell Biol (2014) 0.80
Glucosidase II and MRH-domain containing proteins in the secretory pathway. Curr Protein Pept Sci (2015) 0.80
Adapter-mediated substrate selection for endoplasmic reticulum-associated degradation. J Biol Chem (2009) 0.79
Yos9p: a sweet-toothed bouncer of the secretory pathway. Mol Cell (2005) 0.77
EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog. PLoS One (2014) 0.76
Misfolded proteins induce aggregation of the lectin Yos9. J Biol Chem (2014) 0.76
Function of a p24 Heterodimer in Morphogenesis and Protein Transport in Penicillium oxalicum. Sci Rep (2015) 0.76
Htm1p-Pdi1p is a folding-sensitive mannosidase that marks N-glycoproteins for ER-associated protein degradation. Proc Natl Acad Sci U S A (2016) 0.75
OS9 Protein Interacts with Na-K-2Cl Co-transporter (NKCC2) and Targets Its Immature Form for the Endoplasmic Reticulum-associated Degradation Pathway. J Biol Chem (2015) 0.75
Quality control of glycoprotein folding and ERAD: the role of N-glycan handling, EDEM1 and OS-9. Histochem Cell Biol (2016) 0.75
N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science (2002) 4.04
Multiple phenotypes in phosphoglucomutase 1 deficiency. N Engl J Med (2014) 2.62
Comparative genome analysis of Listeria bacteriophages reveals extensive mosaicism, programmed translational frameshifting, and a novel prophage insertion site. J Bacteriol (2009) 1.56
The terminally redundant, nonpermuted genome of Listeria bacteriophage A511: a model for the SPO1-like myoviruses of gram-positive bacteria. J Bacteriol (2008) 1.44
Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism. Nat Genet (2012) 1.26
Systematic screening of polyphosphate (poly P) levels in yeast mutant cells reveals strong interdependence with primary metabolism. Genome Biol (2006) 1.15
Two distinctly localized p-type ATPases collaborate to maintain organelle homeostasis required for glycoprotein processing and quality control. Mol Biol Cell (2002) 1.04
The 3.4-kDa Ost4 protein is required for the assembly of two distinct oligosaccharyltransferase complexes in yeast. Glycobiology (2005) 1.03
Molecular mechanisms leading to three different phenotypes in the cblD defect of intracellular cobalamin metabolism. Hum Mol Genet (2011) 1.00
Role of E-cadherin N-glycosylation profile in a mammary tumor model. Biochem Biophys Res Commun (2009) 0.95
Major histocompatibility complex class I molecules expressed with monoglucosylated N-linked glycans bind calreticulin independently of their assembly status. J Biol Chem (2004) 0.95
Biosynthesis of lipid-linked oligosaccharides in Saccharomyces cerevisiae: Alg13p and Alg14p form a complex required for the formation of GlcNAc(2)-PP-dolichol. J Biol Chem (2005) 0.95
3-methylcrotonyl-CoA carboxylase deficiency: clinical, biochemical, enzymatic and molecular studies in 88 individuals. Orphanet J Rare Dis (2012) 0.94
Galectins as self/non-self recognition receptors in innate and adaptive immunity: an unresolved paradox. Front Immunol (2012) 0.94
Structural and functional diversity of the lectin repertoire in teleost fish: relevance to innate and adaptive immunity. Dev Comp Immunol (2011) 0.93
N-glycosylation status of E-cadherin controls cytoskeletal dynamics through the organization of distinct β-catenin- and γ-catenin-containing AJs. Cell Health Cytoskelet (2009) 0.91
Aberrant amplification of the crosstalk between canonical Wnt signaling and N-glycosylation gene DPAGT1 promotes oral cancer. Oral Oncol (2012) 0.86
Listeria phage A511, a model for the contractile tail machineries of SPO1-related bacteriophages. Mol Microbiol (2014) 0.85
Characterization of functional domains of the cblD (MMADHC) gene product. J Inherit Metab Dis (2014) 0.84
MAPK scaffolding by BIT1 in the Golgi complex modulates stress resistance. J Cell Sci (2010) 0.84
Coordinate regulation of N-glycosylation gene DPAGT1, canonical Wnt signaling and E-cadherin adhesion. J Cell Sci (2012) 0.83
A single mutation in MCCC1 or MCCC2 as a potential cause of positive screening for 3-methylcrotonyl-CoA carboxylase deficiency. Mol Genet Metab (2011) 0.79
Manipulating galectin expression in zebrafish (Danio rerio). Methods Mol Biol (2015) 0.76