Published in Am J Hum Genet on August 16, 2005
Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder. Schizophr Res (2009) 1.05
Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate. PLoS Genet (2014) 0.92
Positive association of the pericentrin (PCNT) gene with major depressive disorder in the Japanese population. J Psychiatry Neurosci (2009) 0.87
Genome-wide linkage scan of bipolar disorder in a Colombian population isolate replicates Loci on chromosomes 7p21-22, 1p31, 16p12 and 21q21-22 and identifies a novel locus on chromosome 12q. Hum Hered (2010) 0.87
Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet (2011) 0.84
A variable age of onset segregation model for linkage analysis, with correction for ascertainment, applied to glioma. Cancer Epidemiol Biomarkers Prev (2012) 0.83
A non-parametric approach for detecting gene-gene interactions associated with age-at-onset outcomes. BMC Genet (2014) 0.77
Review of the genetic basis of emotion dysregulation in children and adolescents. World J Psychiatry (2015) 0.75
Clinical correlates of age at onset distribution in bipolar disorder: a comparison between diagnostic subgroups. Int J Bipolar Disord (2017) 0.75
MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. Genomics (1987) 54.39
Strategies for multilocus linkage analysis in humans. Proc Natl Acad Sci U S A (1984) 48.41
Linkage of early-onset familial breast cancer to chromosome 17q21. Science (1990) 16.21
Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet (1997) 13.93
A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry (1978) 12.65
Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch Gen Psychiatry (1994) 11.85
Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am J Hum Genet (1990) 9.48
Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage. Am J Hum Genet (1991) 4.19
Ordered subset analysis in genetic linkage mapping of complex traits. Genet Epidemiol (2004) 2.92
A general conditional-logistic model for affected-relative-pair linkage studies. Am J Hum Genet (1999) 2.80
Enhanced pedigree error detection. Hum Hered (2002) 2.65
Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene. Proc Natl Acad Sci U S A (1994) 2.54
Three potential susceptibility loci shown by a genome-wide scan for regions influencing the age at onset of mania. Am J Psychiatry (2004) 2.40
Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. Am J Psychiatry (2001) 2.38
A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3. Nat Genet (1994) 2.30
Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet (1995) 2.09
Model-free linkage analysis with covariates confirms linkage of prostate cancer to chromosomes 1 and 4. Am J Hum Genet (2001) 2.03
Clinical correlates and familial aggregation of age at onset in bipolar disorder. Am J Psychiatry (2006) 1.58
Genome-wide scan and conditional analysis in bipolar disorder: evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees. Biol Psychiatry (2003) 1.49
Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12. Mol Psychiatry (2003) 1.42
Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q. Am J Med Genet (1997) 1.36
Age at onset in bipolar I affective disorder: further evidence for three subgroups. Am J Psychiatry (2003) 1.33
Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 3, 5, 15, 16, 17, and 22. Am J Med Genet (1997) 1.30
Susceptibility loci for bipolar disorder: overlap with inherited vulnerability to schizophrenia. Biol Psychiatry (2000) 1.30
Early age at onset as a risk factor for poor outcome of bipolar disorder. J Psychiatr Res (2003) 1.27
Admixture analysis of age at onset in bipolar I affective disorder. Arch Gen Psychiatry (2001) 1.16
Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X. Am J Med Genet (1997) 1.15
Use of the Research Diagnostic Criteria and the Schedule for Affective Disorders and Schizophrenia to study affective disorders. Am J Psychiatry (1979) 1.14
Multipoint affected sibpair linkage methods for localizing susceptibility genes of complex diseases. Genet Epidemiol (2003) 1.12
Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12. Am J Med Genet (1997) 1.10
Phenomenology and outcome of subjects with early- and adult-onset psychotic mania. Am J Psychiatry (2000) 1.10
A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus. Am J Hum Genet (1999) 1.07
The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report. Mol Psychiatry (2002) 1.07
Mixture models for linkage analysis of affected sibling pairs and covariates. Genet Epidemiol (2002) 1.06
Incorporation of covariates into genome scanning using sib-pair analysis in bipolar affective disorder. Genet Epidemiol (1997) 1.06
Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q. Am J Hum Genet (1996) 1.03
Different familial transmission patterns in bipolar I disorder with onset before and after age 25. Am J Med Genet (2001) 1.03
Examination of IMPA1 and IMPA2 genes in manic-depressive patients: association between IMPA2 promoter polymorphisms and bipolar disorder. Mol Psychiatry (2004) 1.01
Linkage analysis of families with bipolar illness and chromosome 18 markers. Biol Psychiatry (1996) 1.00
Genome scan of the fifty-six bipolar pedigrees from the NIMH genetics initiative replication sample: chromosomes 4, 7, 9, 18, 19, 20, and 21. Am J Med Genet B Neuropsychiatr Genet (2003) 0.96
Genome scan of a second wave of NIMH genetics initiative bipolar pedigrees: chromosomes 2, 11, 13, 14, and X. Am J Med Genet B Neuropsychiatr Genet (2003) 0.93
Apparent replication of suggestive linkage on chromosome 16 in the NIMH genetics initiative bipolar pedigrees. Am J Med Genet (2002) 0.92
Sibling pairs with affective disorders: resemblance of demographic and clinical features. Psychol Med (2002) 0.89
A follow-up linkage study supports evidence for a bipolar affective disorder locus on chromosome 21q22. Am J Med Genet (2001) 0.84
Parental transmission and D18S37 allele sharing in bipolar affective disorder. Genet Epidemiol (1997) 0.84
A comparison of outcome in adolescent- and later-onset bipolar manic-depressive illness. Am J Psychiatry (1977) 0.84
A human myo-inositol monophosphatase gene (IMPA2) localized in a putative susceptibility region for bipolar disorder on chromosome 18p11.2: genomic structure and polymorphism screening in manic-depressive patients. Mol Psychiatry (2000) 0.82
Description of the National Institute of Mental Health family study of affective disorders. Genet Epidemiol (1989) 0.77
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
DNA methylation signatures within the human brain. Am J Hum Genet (2007) 3.50
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron (2011) 3.08
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02
Results of a high-resolution genome screen of 437 Alzheimer's disease families. Hum Mol Genet (2003) 3.00
Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Am J Psychiatry (2007) 2.84
Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals. Genome Res (2013) 2.77
Antihypertensive medication use and incident Alzheimer disease: the Cache County Study. Arch Neurol (2006) 2.71
Nonsteroidal anti-inflammatory drugs for the prevention of Alzheimer's disease: a systematic review. Neuroepidemiology (2004) 2.63
Psychiatric genetics: progress amid controversy. Nat Rev Genet (2008) 2.51
Hormone therapy and Alzheimer disease dementia: new findings from the Cache County Study. Neurology (2012) 1.96
Comorbid bipolar disorder and panic disorder in families with a high prevalence of bipolar disorder. Am J Psychiatry (2002) 1.87
Genome-wide association study of suicide attempts in mood disorder patients. Am J Psychiatry (2010) 1.85
Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33. Am J Psychiatry (2007) 1.85
Vascular risk factors for incident Alzheimer disease and vascular dementia: the Cache County study. Alzheimer Dis Assoc Disord (2006) 1.85
Statin use and the risk of incident dementia: the Cardiovascular Health Study. Arch Neurol (2005) 1.76
Genetics of recurrent early-onset major depression (GenRED): final genome scan report. Am J Psychiatry (2007) 1.76
Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans. Biol Psychiatry (2010) 1.70
Apolipoprotein E epsilon4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study. Arch Gen Psychiatry (2004) 1.67
Chronic corticosterone exposure increases expression and decreases deoxyribonucleic acid methylation of Fkbp5 in mice. Endocrinology (2010) 1.65
Effects of family history and apolipoprotein E epsilon4 status on cognitive decline in the absence of Alzheimer dementia: the Cache County Study. Arch Neurol (2009) 1.63
Clinical correlates and familial aggregation of age at onset in bipolar disorder. Am J Psychiatry (2006) 1.58
Further development of YBOCS dimensions in the OCD Collaborative Genetics study: symptoms vs. categories. Psychiatry Res (2008) 1.54
C9ORF72 expansion in a family with bipolar disorder. Bipolar Disord (2013) 1.54
Hippocampal and ventricular volumes in psychotic and nonpsychotic bipolar patients compared with schizophrenia patients and community control subjects: a pilot study. Biol Psychiatry (2005) 1.50
Genome-wide scan and conditional analysis in bipolar disorder: evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees. Biol Psychiatry (2003) 1.49
Genetics of recurrent early-onset major depression (GenRED): significant linkage on chromosome 15q25-q26 after fine mapping with single nucleotide polymorphism markers. Am J Psychiatry (2007) 1.43
Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness): a pragmatic 6-month trial of lithium versus quetiapine for bipolar disorder. J Clin Psychiatry (2016) 1.43
Diagnostic reliability of bipolar II disorder. Arch Gen Psychiatry (2002) 1.42
Hoarding in obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Behav Res Ther (2006) 1.41
The bipolar disorder phenome database: a resource for genetic studies. Am J Psychiatry (2007) 1.41
Reproductive cycle-associated mood symptoms in women with major depression and bipolar disorder. J Affect Disord (2006) 1.39
Suggestive linkage to chromosomal regions 13q31 and 22q12 in families with psychotic bipolar disorder. Am J Psychiatry (2003) 1.36
Clock genes may influence bipolar disorder susceptibility and dysfunctional circadian rhythm. Am J Med Genet B Neuropsychiatr Genet (2008) 1.35
Genomewide significant linkage to recurrent, early-onset major depressive disorder on chromosome 15q. Am J Hum Genet (2004) 1.32
A review of the evidence from family, twin and adoption studies for a genetic contribution to adult psychiatric disorders. Int Rev Psychiatry (2004) 1.32
Intermediate: cognitive phenotypes in bipolar disorder. J Affect Disord (2009) 1.28
Genetics of recurrent early-onset depression (GenRED): design and preliminary clinical characteristics of a repository sample for genetic linkage studies. Am J Med Genet B Neuropsychiatr Genet (2003) 1.26
Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. PLoS Genet (2011) 1.23
Familiality of factor analysis-derived YBOCS dimensions in OCD-affected sibling pairs from the OCD Collaborative Genetics Study. Biol Psychiatry (2006) 1.22
Genome-wide linkage and follow-up association study of postpartum mood symptoms. Am J Psychiatry (2009) 1.21
Genome-wide DNA methylation scan in major depressive disorder. PLoS One (2012) 1.17
Validation and assessment of variant calling pipelines for next-generation sequencing. Hum Genomics (2014) 1.16
A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice. Psychopharmacology (Berl) (2011) 1.16
Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees. Biol Psychiatry (2004) 1.13
Future of genetics of mood disorders research. Biol Psychiatry (2002) 1.11
Association between APOE epsilon4 allele and vascular dementia: The Cache County study. Dement Geriatr Cogn Disord (2010) 1.10
Three-year incidence of first-onset depressive syndrome in a population sample of older adults: the Cache County study. Am J Geriatr Psychiatry (2006) 1.10
Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. Am J Hum Genet (2013) 1.10
Apolipoprotein E genotype and mortality: findings from the Cache County Study. J Am Geriatr Soc (2005) 1.10
The OCD collaborative genetics study: methods and sample description. Am J Med Genet B Neuropsychiatr Genet (2006) 1.08
Relationship between cortisol responses to stress and personality. Neuropsychopharmacology (2006) 1.08
CRELD1 mutations contribute to the occurrence of cardiac atrioventricular septal defects in Down syndrome. Am J Med Genet A (2006) 1.07
Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults. Psychopharmacology (Berl) (2012) 1.06
Differential expression of disrupted-in-schizophrenia (DISC1) in bipolar disorder. Biol Psychiatry (2006) 1.06
Systematic review of genome-wide gene expression studies of bipolar disorder. BMC Psychiatry (2013) 1.06
NSAIDs for the chemoprevention of Alzheimer's disease. Subcell Biochem (2007) 1.06
Gender differences in the association between religious involvement and depression: the Cache County (Utah) study. J Gerontol B Psychol Sci Soc Sci (2006) 1.06