Published in Bioorg Med Chem Lett on September 23, 2005
Environmental impact on vascular development predicted by high-throughput screening. Environ Health Perspect (2011) 1.05
A computational model predicting disruption of blood vessel development. PLoS Comput Biol (2013) 0.89
Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma. Acta Biochim Biophys Sin (Shanghai) (2013) 0.88
Expression of the cereblon binding protein argonaute 2 plays an important role for multiple myeloma cell growth and survival. BMC Cancer (2016) 0.75
Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion. J Biol Chem (2003) 3.30
Isolation of hepatoblasts based on the expression of Dlk/Pref-1. J Cell Sci (2003) 2.38
Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver. Development (2009) 2.26
Antigen-receptor genes of the agnathan lamprey are assembled by a process involving copy choice. Nat Immunol (2006) 1.89
Hypertrophy and unconventional cell division of hepatocytes underlie liver regeneration. Curr Biol (2012) 1.79
Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors. J Cell Sci (2004) 1.78
The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop. Mol Cell Biol (2009) 1.78
Dlk-1, a cell surface antigen on foetal hepatic stem/progenitor cells, is expressed in hepatocellular, colon, pancreas and breast carcinomas at a high frequency. J Biochem (2010) 1.73
Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis. J Exp Med (2005) 1.72
Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis. Proc Natl Acad Sci U S A (2012) 1.61
Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis. Proc Natl Acad Sci U S A (2003) 1.61
Novel non-steroidal/non-anilide type androgen antagonists with an isoxazolone moiety. Bioorg Med Chem (2002) 1.53
A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer's disease-relevant insults. Eur J Neurosci (2003) 1.52
Discovery of oxysterol-derived pharmacological chaperones for NPC1: implication for the existence of second sterol-binding site. Chem Biol (2013) 1.49
Improvement in aqueous solubility in small molecule drug discovery programs by disruption of molecular planarity and symmetry. J Med Chem (2011) 1.45
Liver progenitor cells develop cholangiocyte-type epithelial polarity in three-dimensional culture. Mol Biol Cell (2007) 1.44
Targeted disruption of oncostatin M receptor results in altered hematopoiesis. Blood (2003) 1.43
Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells. Blood (2005) 1.41
Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults. Neurosci Lett (2002) 1.39
Retracted A cell cycle-dependent co-repressor mediates photoreceptor cell-specific nuclear receptor function. EMBO J (2007) 1.39
TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/EBPbeta. J Biol Chem (2007) 1.35
MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma. Biomarkers (2009) 1.35
Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos. Blood (2003) 1.34
Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: drastic change of EpCAM expression during liver development. Mech Dev (2009) 1.32
Cytokine regulation of liver development. Biochim Biophys Acta (2002) 1.29
Crystal structure of Vigna radiata cytokinin-specific binding protein in complex with zeatin. Plant Cell (2006) 1.29
Liver stem/progenitor cells: their characteristics and regulatory mechanisms. J Biochem (2011) 1.29
A Rac1/phosphatidylinositol 3-kinase/Akt3 anti-apoptotic pathway, triggered by AlsinLF, the product of the ALS2 gene, antagonizes Cu/Zn-superoxide dismutase (SOD1) mutant-induced motoneuronal cell death. J Biol Chem (2004) 1.26
Hepatocyte proliferation and tissue remodeling is impaired after liver injury in oncostatin M receptor knockout mice. Hepatology (2004) 1.25
Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin. J Cell Biol (2008) 1.23
miR-148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells. Hepatology (2013) 1.22
Liver regeneration by stem/progenitor cells. Hepatology (2014) 1.17
A nonclassical vitamin D receptor pathway suppresses renal fibrosis. J Clin Invest (2013) 1.16
Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25. Mol Biol Cell (2012) 1.15
Long-term culture of hepatic progenitors derived from mouse Dlk+ hepatoblasts. J Cell Sci (2004) 1.14
p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver. Gastroenterology (2008) 1.14
Essential function of oncostatin m in nociceptive neurons of dorsal root ganglia. J Neurosci (2004) 1.14
Mono- and dihydroxylated metabolites of thalidomide: synthesis and TNF-alpha production-inhibitory activity. Chem Pharm Bull (Tokyo) (2006) 1.13
Direct ortho cupration: a new route to regioselectively functionalized aromatics. J Am Chem Soc (2007) 1.13
S-nitrosothiol depletion in amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A (2006) 1.11
Separation of alpha-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRalpha-selective antagonists. Bioorg Med Chem (2009) 1.10
A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB. Cell Signal (2007) 1.09
Hepatic stellate cell-derived delta-like homolog 1 (DLK1) protein in liver regeneration. J Biol Chem (2012) 1.07
Characterization and functional analyses of hepatic mesothelial cells in mouse liver development. Gastroenterology (2010) 1.07
FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev (2013) 1.05
K-Ras mediates cytokine-induced formation of E-cadherin-based adherens junctions during liver development. EMBO J (2002) 1.05
Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization. J Neurochem (2003) 1.05
Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins. J Am Chem Soc (2010) 1.04
Death and survival of neuronal cells exposed to Alzheimer's insults. J Neurosci Res (2002) 1.02
Total synthesis of batzelladine D. Org Lett (2002) 1.01
Liver progenitor cells fold up a cell monolayer into a double-layered structure during tubular morphogenesis. Mol Biol Cell (2009) 1.00
Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells. Exp Cell Res (2009) 1.00
Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults. Peptides (2003) 1.00
Development of murine hepatic sinusoidal endothelial cells characterized by the expression of hyaluronan receptors. Dev Dyn (2007) 0.99
Macrophage colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region. Blood (2002) 0.99
Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants. J Biol Chem (2004) 0.99
Molecular mechanism of liver development and regeneration. Int Rev Cytol (2007) 0.98
Mitochondria and apicoplast of Plasmodium falciparum: behaviour on subcellular fractionation and the implication. Mitochondrion (2006) 0.98
Novel retinoid X receptor antagonists: specific inhibition of retinoid synergism in RXR-RAR heterodimer actions. J Med Chem (2002) 0.97
Oncostatin M inhibits adipogenesis through the RAS/ERK and STAT5 signaling pathways. J Biol Chem (2006) 0.97
Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells. J Neurosci Res (2003) 0.97
Nucleocytoplasmic shuttling of the zinc finger protein EZI Is mediated by importin-7-dependent nuclear import and CRM1-independent export mechanisms. J Biol Chem (2007) 0.96
Transcription elongation factor S-II is required for definitive hematopoiesis. Mol Cell Biol (2006) 0.95
STAT3 down-regulates the expression of cyclin D during liver development. J Biol Chem (2002) 0.95
C(2)-symmetric chiral pentacyclic guanidine: a phase-transfer catalyst for the asymmetric alkylation of tert-butyl glycinate Schiff base. Angew Chem Int Ed Engl (2002) 0.95
Prospero-related homeobox 1 and liver receptor homolog 1 coordinately regulate long-term proliferation of murine fetal hepatoblasts. Hepatology (2008) 0.95
Anti-influenza activity of phenethylphenylphthalimide analogs derived from thalidomide. Bioorg Med Chem (2010) 0.94
Inducible expression of Wnt genes during adult hepatic stem/progenitor cell response. FEBS Lett (2009) 0.94
Expression of Dlk/Pref-1 defines a subpopulation in the oval cell compartment of rat liver. Gene Expr Patterns (2004) 0.93
Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development. EMBO J (2007) 0.93
α1- and α5-containing laminins regulate the development of bile ducts via β1 integrin signals. J Biol Chem (2012) 0.93
A novel regulatory mechanism for Fgf18 signaling involving cysteine-rich FGF receptor (Cfr) and delta-like protein (Dlk). Development (2010) 0.93
Suppression of beta-catenin signaling by liver X receptor ligands. Biochem Pharmacol (2008) 0.93
Runx1 promotes angiogenesis by downregulation of insulin-like growth factor-binding protein-3. Oncogene (2005) 0.92
Oncostatin M inhibits proliferation of rat oval cells, OC15-5, inducing differentiation into hepatocytes. Am J Pathol (2005) 0.91
Isolation of the bioactive peptides CCHamide-1 and CCHamide-2 from Drosophila and their putative role in appetite regulation as ligands for G protein-coupled receptors. Front Endocrinol (Lausanne) (2012) 0.91
To divide or not to divide: revisiting liver regeneration. Cell Div (2013) 0.91
Oncostatin M gene therapy attenuates liver damage induced by dimethylnitrosamine in rats. Am J Pathol (2007) 0.90
Nrf2 enhances cholangiocyte expansion in Pten-deficient livers. Mol Cell Biol (2013) 0.90
Liver X receptor antagonists with a phthalimide skeleton derived from thalidomide-related glucosidase inhibitors. Bioorg Med Chem Lett (2007) 0.90
Humanin and the receptors for humanin. Mol Neurobiol (2009) 0.90
Total synthesis of crambescidin 359. Org Lett (2002) 0.90
Cutting Edge: A possible role for CD4+ thymic macrophages as professional scavengers of apoptotic thymocytes. J Immunol (2003) 0.90
Adaptability and selectivity of human peroxisome proliferator-activated receptor (PPAR) pan agonists revealed from crystal structures. Acta Crystallogr D Biol Crystallogr (2009) 0.89
Hepatoma-derived growth factor is highly expressed in developing liver and promotes fetal hepatocyte proliferation. Hepatology (2002) 0.89
Regulation of annexin II by cytokine-initiated signaling pathways and E2A-HLF oncoprotein. Blood (2003) 0.89
Origin of chemoselectivity of TMP zincate bases and differences between TMP zincate and alkyl lithium reagents: a DFT study on model systems. Angew Chem Int Ed Engl (2007) 0.89
Identification of a new organic anion transporting polypeptide 1B3 mRNA isoform primarily expressed in human cancerous tissues and cells. Biochem Biophys Res Commun (2012) 0.88
LXXLL peptide mimetics as inhibitors of the interaction of vitamin D receptor with coactivators. Bioorg Med Chem Lett (2010) 0.88
Expression of oncostatin M receptor beta in a specific subset of nociceptive sensory neurons. Eur J Neurosci (2003) 0.88
Nuclear receptor antagonists designed based on the helix-folding inhibition hypothesis. Bioorg Med Chem (2005) 0.88
Hydrolyzed metabolites of thalidomide: synthesis and TNF-alpha production-inhibitory activity. Chem Pharm Bull (Tokyo) (2007) 0.88