PubRank

Annette G Beck-Sickinger

Author PubWeight™ 122.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 GPR39 signaling is stimulated by zinc ions but not by obestatin. Endocrinology 2006 1.60
2 Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex. J Am Soc Mass Spectrom 2006 1.31
3 Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. J Exp Med 2008 1.27
4 Neuropeptide Y stimulates neuronal precursor proliferation in the post-natal and adult dentate gyrus. J Neurochem 2005 1.26
5 The anti-epileptic actions of neuropeptide Y in the hippocampus are mediated by Y and not Y receptors. Eur J Neurosci 2005 1.10
6 Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers. Biophys J 2008 1.10
7 Peptide drugs to target G protein-coupled receptors. Trends Pharmacol Sci 2010 1.09
8 In vivo characterization of high Basal signaling from the ghrelin receptor. Endocrinology 2009 1.08
9 Decoding the entry of two novel cell-penetrating peptides in HeLa cells: lipid raft-mediated endocytosis and endosomal escape. Biochemistry 2005 1.08
10 Molecular mechanisms of signal transduction via adiponectin and adiponectin receptors. Biol Chem 2010 1.08
11 Characterization of the interaction of interleukin-8 with hyaluronan, chondroitin sulfate, dermatan sulfate and their sulfated derivatives by spectroscopy and molecular modeling. Glycobiology 2011 1.07
12 Homodimerization of neuropeptide y receptors investigated by fluorescence resonance energy transfer in living cells. J Biol Chem 2003 1.05
13 Expressed protein ligation. Method and applications. Eur J Biochem 2004 1.04
14 Promiscuous modification of the nuclear poly(A)-binding protein by multiple protein-arginine methyltransferases does not affect the aggregation behavior. J Biol Chem 2008 1.02
15 Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine. Clin Sci (Lond) 2008 1.00
16 Artificial chemokines: combining chemistry and molecular biology for the elucidation of interleukin-8 functionality. J Am Chem Soc 2008 1.00
17 The third intracellular loop stabilizes the inactive state of the neuropeptide Y1 receptor. J Biol Chem 2008 1.00
18 Biochemical characterisation and genetic analysis of aureocin A53, a new, atypical bacteriocin from Staphylococcus aureus. J Mol Biol 2002 0.98
19 A Y2 receptor mimetic aptamer directed against neuropeptide Y. J Biol Chem 2001 0.98
20 Metabolic cleavage of cell-penetrating peptides in contact with epithelial models: human calcitonin (hCT)-derived peptides, Tat(47-57) and penetratin(43-58). Biochem J 2004 0.98
21 Agonist induced receptor internalization of neuropeptide Y receptor subtypes depends on third intracellular loop and C-terminus. Cell Signal 2008 0.97
22 Blockade of neuropeptide Y(2) receptors and suppression of NPY's anti-epileptic actions in the rat hippocampal slice by BIIE0246. Br J Pharmacol 2002 0.97
23 Glutamate release by neurons evokes a purinergic inhibitory mechanism of osmotic glial cell swelling in the rat retina: activation by neuropeptide Y. J Neurosci Res 2006 0.96
24 Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism. J Biol Chem 2007 0.96
25 Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively. J Biol Chem 2009 0.95
26 Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation. J Med Chem 2011 0.94
27 Neuropeptide Y receptors: how to get subtype selectivity. Front Endocrinol (Lausanne) 2013 0.94
28 Peptides and peptide conjugates: therapeutics on the upward path. Future Med Chem 2012 0.93
29 Electron paramagnetic resonance backbone dynamics studies on spin-labelled neuropeptide Y analogues. J Pept Sci 2002 0.92
30 Illuminating the life of GPCRs. Cell Commun Signal 2009 0.92
31 Chemical and biological characterization of new Re(CO)3/[99mTc](CO)3 bombesin analogues. Nucl Med Biol 2006 0.91
32 Proteome analysis to study signal transduction of G protein-coupled receptors. Pharmacol Ther 2006 0.91
33 Multiple NPY receptors Inhibit GABA(A) synaptic responses of rat medial parvocellular effector neurons in the hypothalamic paraventricular nucleus. Endocrinology 2002 0.89
34 Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands. J Biol Chem 2007 0.89
35 Neuropeptide Y receptors: ligand binding and trafficking suggest novel approaches in drug development. J Pept Sci 2011 0.88
36 Ghrelin receptor: high constitutive activity and methods for developing inverse agonists. Methods Enzymol 2010 0.88
37 Ghrelin--a novel generation of anti-obesity drug: design, pharmacomodulation and biological activity of ghrelin analogues. J Pept Sci 2009 0.88
38 Dimerization of adiponectin receptor 1 is inhibited by adiponectin. J Cell Sci 2010 0.88
39 Ligand-induced internalization and recycling of the human neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail. J Biol Chem 2010 0.88
40 Molecular recognition of the NPY hormone family by their receptors. Nutrition 2008 0.87
41 In vitro and in vivo evaluation of a 99mTc(I)-labeled bombesin analogue for imaging of gastrin releasing peptide receptor-positive tumors. Nucl Med Biol 2002 0.87
42 Towards improved receptor targeting: anterograde transport, internalization and postendocytic trafficking of neuropeptide Y receptors. Biol Chem 2013 0.86
43 A novel, biased-like SDF-1 derivative acts synergistically with starPEG-based heparin hydrogels and improves eEPC migration in vitro. J Control Release 2012 0.86
44 Targeted tumor diagnosis and therapy with peptide hormones as radiopharmaceuticals. Anticancer Agents Med Chem 2008 0.86
45 Analogues of neuropeptide Y containing beta-aminocyclopropane carboxylic acids are the shortest linear peptides that are selective for the Y1 receptor. Angew Chem Int Ed Engl 2003 0.85
46 Central NPY receptor-mediated alteration of heart rate dynamics in mice during expression of fear conditioned to an auditory cue. Regul Pept 2004 0.85
47 Tracking of human Y receptors in living cells--a fluorescence approach. Peptides 2007 0.85
48 Novel chemically modified analogues of neuropeptide Y for tumor targeting. Bioconjug Chem 2008 0.85
49 Breast-cancer diagnosis by neuropeptide Y analogues: from synthesis to clinical application. Angew Chem Int Ed Engl 2010 0.84
50 Identification of the key residue of calcitonin gene related peptide (CGRP) 27-37 to obtain antagonists with picomolar affinity at the CGRP receptor. J Med Chem 2006 0.84
51 Vaspin inhibits kallikrein 7 by serpin mechanism. Cell Mol Life Sci 2013 0.84
52 Large scale modification of biomolecules using immobilized sortase A from Staphylococcus aureus. Bioorg Med Chem 2013 0.84
53 Structure-activity studies of RFamide peptides reveal subtype-selective activation of neuropeptide FF1 and FF2 receptors. ChemMedChem 2011 0.84
54 Cellular uptake but low permeation of human calcitonin-derived cell penetrating peptides and Tat(47-57) through well-differentiated epithelial models. Pharm Res 2004 0.84
55 Developing novel hCT derived cell-penetrating peptides with improved metabolic stability. Biochim Biophys Acta 2005 0.84
56 Processing, signaling, and physiological function of chemerin. IUBMB Life 2014 0.83
57 Membrane interaction of neuropeptide Y detected by EPR and NMR spectroscopy. Biochim Biophys Acta 2005 0.83
58 Presence of neuropeptide Y and the Y1 receptor in the plasma membrane and nuclear envelope of human endocardial endothelial cells: modulation of intracellular calcium. Can J Physiol Pharmacol 2003 0.83
59 Protein kinase CK2 interacts with adiponectin receptor 1 and participates in adiponectin signaling. Cell Signal 2009 0.83
60 Neuropeptide Y suppresses absence seizures in a genetic rat model primarily through effects on Y receptors. Eur J Neurosci 2007 0.83
61 Specifically immobilised aldo/keto reductase AKR1A1 shows a dramatic increase in activity relative to the randomly immobilised enzyme. Chembiochem 2007 0.83
62 Fluorescence- and luminescence-based methods for the determination of affinity and activity of neuropeptide Y2 receptor ligands. Eur J Pharmacol 2006 0.83
63 The SK-N-MC cell line expresses an orexin binding site different from recombinant orexin 1-type receptor. Eur J Biochem 2002 0.83
64 Guanidine-acylguanidine bioisosteric approach in the design of radioligands: synthesis of a tritium-labeled N(G)-propionylargininamide ([3H]-UR-MK114) as a highly potent and selective neuropeptide Y Y1 receptor antagonist. J Med Chem 2008 0.83
65 Comparative analysis of the signaling capabilities of the insulin receptor-related receptor. Biochem Biophys Res Commun 2005 0.83
66 Pyridone dipeptide backbone scan to elucidate structural properties of a flexible peptide segment. J Am Chem Soc 2008 0.82
67 Semisynthesis and application of carboxyfluorescein-labelled biologically active human interleukin-8. Biol Chem 2003 0.82
68 Calcitonin-derived peptide carriers: mechanisms and application. Adv Drug Deliv Rev 2007 0.82
69 Identification of neuropeptide Y cleavage products in human blood to improve metabolic stability. Biopolymers 2007 0.82
70 Nano-high-performance liquid chromatography in combination with nano-electrospray ionization Fourier transform ion-cyclotron resonance mass spectrometry for proteome analysis. Rapid Commun Mass Spectrom 2003 0.82
71 Strongly altered receptor binding properties in PP and NPY chimeras are accompanied by changes in structure and membrane binding. Biochemistry 2005 0.82
72 GPC receptors and not ligands decide the binding mode in neuropeptide Y multireceptor/multiligand system. Biochemistry 2008 0.82
73 Structure-activity studies of orexin a and orexin B at the human orexin 1 and orexin 2 receptors led to orexin 2 receptor selective and orexin 1 receptor preferring ligands. J Med Chem 2004 0.82
74 A novel type of macrothrombocytopenia associated with a defect in α2,3-sialylation. Am J Pathol 2011 0.82
75 Agonists for neuropeptide Y receptors Y1 and Y5 stimulate different phases of feeding in guinea pigs. Br J Pharmacol 2003 0.81
76 Molecular tools to characterize adiponectin activity. Vitam Horm 2012 0.81
77 First selective agonist of the neuropeptide Y1-receptor with reduced size. J Pept Sci 2009 0.81
78 An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor. J Med Chem 2012 0.81
79 Design, evaluation, and comparison of ghrelin receptor agonists and inverse agonists as suitable radiotracers for PET imaging. Bioconjug Chem 2012 0.81
80 Drug delivery and release systems for targeted tumor therapy. J Pept Sci 2015 0.81
81 Expressed enzymatic ligation for the semisynthesis of chemically modified proteins. Angew Chem Int Ed Engl 2003 0.81
82 Unique interaction pattern for a functionally biased ghrelin receptor agonist. J Biol Chem 2011 0.81
83 Localization of novel adiponectin receptor constructs. J Recept Signal Transduct Res 2006 0.81
84 The neuropeptide Y monomer in solution is not folded in the pancreatic-polypeptide fold. Protein Sci 2002 0.80
85 Functional role of the extracellular N-terminal domain of neuropeptide Y subfamily receptors in membrane integration and agonist-stimulated internalization. Cell Signal 2008 0.80
86 Membrane surface-associated helices promote lipid interactions and cellular uptake of human calcitonin-derived cell penetrating peptides. Biophys J 2005 0.80
87 Chemerin and vaspin: possible targets to treat obesity? ChemMedChem 2012 0.80
88 Asborin inhibits Aldo/Keto reductase 1A1. ChemMedChem 2011 0.80
89 Access to gram scale amounts of functional globular adiponectin from E. coli inclusion bodies by alkaline-shock solubilization. Biochem Biophys Res Commun 2010 0.80
90 NPY modulates epinephrine-induced leukocytosis via Y-1 and Y-5 receptor activation in vivo: sympathetic co-transmission during leukocyte mobilization. J Neuroimmunol 2002 0.80
91 Identification of a potential modification site in human stromal cell-derived factor-1. Biopolymers 2010 0.80
92 Palmitoylated SDF1α shows increased resistance against proteolytic degradation in liver homogenates. ChemMedChem 2011 0.80
93 Toward the application of proteomics to human thyroid tissue. Thyroid 2006 0.80
94 Generation of carrier peptides for the delivery of nucleic acid drugs in primary cells. ChemMedChem 2008 0.80
95 Peptide-templated acyl transfer: a chemical method for the labeling of membrane proteins on live cells. Angew Chem Int Ed Engl 2014 0.79
96 Facile and selective nanoscale labeling of peptides in solution by using photolabile protecting groups. J Med Chem 2003 0.79
97 Central nervous system neuropeptide Y signaling via the Y1 receptor partially dissociates feeding behavior from lipoprotein metabolism in lean rats. Am J Physiol Endocrinol Metab 2012 0.79
98 Photoactivatable chemokines--controlling protein activity by light. Angew Chem Int Ed Engl 2013 0.79
99 Bilayer interaction and localization of cell penetrating peptides with model membranes: a comparative study of a human calcitonin (hCT)-derived peptide with pVEC and pAntp(43-58). Biochim Biophys Acta 2005 0.79
100 Proteolytic activation of prochemerin by kallikrein 7 breaks an ionic linkage and results in C-terminal rearrangement. Biochem J 2013 0.79
101 Cellular internalization of enhanced green fluorescent protein ligated to a human calcitonin-based carrier peptide. Chembiochem 2002 0.79
102 In vitro gene delivery by a novel human calcitonin (hCT)-derived carrier peptide. Bioorg Med Chem Lett 2004 0.79
103 Cellular internalization of human calcitonin derived peptides in MDCK monolayers: a comparative study with Tat(47-57) and penetratin(43-58). Pharm Res 2004 0.79
104 Structural investigations of a human calcitonin-derived carrier peptide in a membrane environment by solid-state NMR. Biochemistry 2004 0.79
105 Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket. J Biol Chem 2013 0.78
106 Adiponectin receptor 1 interacts with both subunits of protein kinase CK2. Mol Cell Biochem 2011 0.78
107 Adiponectin promotes the migration of circulating angiogenic cells through p38-mediated induction of the CXCR4 receptor. Int J Cardiol 2012 0.78
108 Vaspin--a link of obesity and psoriasis? Exp Dermatol 2012 0.78
109 The interaction of neuropeptide Y with negatively charged and zwitterionic phospholipid membranes. Eur Biophys J 2009 0.78
110 Novel daunorubicin-carrier peptide conjugates derived from human calcitonin segments. J Mol Recognit 2003 0.78
111 Structural properties of orexins for activation of their receptors. J Pept Sci 2006 0.78
112 Ala31-Aib32: identification of the key motif for high affinity and selectivity of neuropeptide Y at the Y5-receptor. Biochemistry 2002 0.78
113 Peptide modifications differentially alter G protein-coupled receptor internalization and signaling bias. Angew Chem Int Ed Engl 2014 0.78
114 The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion. PLoS One 2013 0.78
115 Simultaneous "one pot" expressed protein ligation and CuI-catalyzed azide/alkyne cycloaddition for protein immobilization. Chembiochem 2011 0.78
116 Residue 75 of interleukin-8 is crucial for its interactions with glycosaminoglycans. Chembiochem 2012 0.78
117 Microscopic mechanism of specific peptide adhesion to semiconductor substrates. Angew Chem Int Ed Engl 2010 0.78
118 Investigation of lysine side chain interactions of interleukin-8 with heparin and other glycosaminoglycans studied by a methylation-NMR approach. Glycobiology 2013 0.77
119 Peptide backbone conformation affects the substrate preference of protein arginine methyltransferase I. Biochemistry 2012 0.77
120 Incorporation of ortho-carbaboranyl-Nε-modified L-lysine into neuropeptide Y receptor Y1- and Y2-selective analogues. J Med Chem 2011 0.77
121 Two motifs with different function regulate the anterograde transport of the adiponectin receptor 1. Cell Signal 2012 0.77
122 Ligand-mimicking receptor variant discloses binding and activation mode of prolactin-releasing peptide. J Biol Chem 2012 0.77
123 Active contractions in single suspended epithelial cells. Eur Biophys J 2013 0.77
124 Position and length of fatty acids strongly affect receptor selectivity pattern of human pancreatic polypeptide analogues. ChemMedChem 2014 0.77
125 Towards understanding the free and receptor bound conformation of neuropeptide Y by fluorescence resonance energy transfer studies. Chem Biol Drug Des 2009 0.77
126 The anterograde transport of the human neuropeptide Y2 receptor is regulated by a subtype specific mechanism mediated by the C-terminus. Neuropeptides 2012 0.77
127 A reconstitution protocol for the in vitro folded human G protein-coupled Y2 receptor into lipid environment. Biophys Chem 2010 0.77
128 Preparation of C-terminally modified chemokines by expressed protein ligation. Methods Mol Biol 2013 0.76
129 Microelectrode chip based real time monitoring of vital MCF-7 mamma carcinoma cells by impedance spectroscopy. Biosens Bioelectron 2008 0.76
130 Biocompatible silicon surfaces through orthogonal click chemistries and a high affinity silicon oxide binding peptide. Bioconjug Chem 2012 0.76
131 Prokaryotic expression, in vitro folding, and molecular pharmacological characterization of the neuropeptide Y receptor type 2. Biotechnol Prog 2009 0.76
132 Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY. Biochemistry 2002 0.76
133 Receptor-mediated uptake of boron-rich neuropeptide y analogues for boron neutron capture therapy. ChemMedChem 2014 0.76
134 In vitro modification of substituted cysteines as tool to study receptor functionality and structure-activity relationships. Anal Biochem 2013 0.76
135 Selective mode of action of guanidine-containing non-peptides at human NPFF receptors. J Med Chem 2012 0.76
136 Controlling toxicity of Peptide-drug conjugates by different chemical linker structures. ChemMedChem 2015 0.76
137 Semisynthesis and characterization of the first analogues of pro-neuropeptide y. Chembiochem 2003 0.76
138 Determination of affinity and activity of ligands at the human neuropeptide Y Y4 receptor by flow cytometry and aequorin luminescence. J Recept Signal Transduct Res 2007 0.76
139 Molecular ligand-receptor interaction of the NPY/PP peptide family. EXS 2006 0.76
140 Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels. J Mol Med (Berl) 2013 0.75
141 The first reporter gene assay on living cells: green fluorescent protein as reporter gene for the investigation of Gi-protein coupled receptors. Mol Biotechnol 2002 0.75
142 On-resin synthesis of an acylated and fluorescence-labeled cyclic integrin ligand for modification of poly(lactic-co-glycolic acid). Chem Biodivers 2012 0.75
143 The activity of prolactin releasing peptide correlates with its helicity. Biopolymers 2013 0.75
144 One-step procedure for staining of proteins with ruthenium II tris (bathophenanthroline disulfonate). Anal Biochem 2006 0.75
145 Structure-activity relationship studies: methods and ligand design for G-protein coupled peptide receptors. Curr Protein Pept Sci 2006 0.75
146 Expressed protein ligation to obtain selectively modified aldo/keto reductases. Protein Pept Lett 2005 0.75
147 On-resin Diels-Alder reaction with inverse electron demand: an efficient ligation method for complex peptides with a varying spacer to optimize cell adhesion. Org Biomol Chem 2016 0.75
148 Assessment of a fully active class A G protein-coupled receptor isolated from in vitro folding. Biochemistry 2011 0.75
149 Multifunctional biomaterial coatings: synthetic challenges and biological activity. Biol Chem 2017 0.75
150 Tetrafunctional photoaffinity labels based on Nakanishi's m-nitroalkoxy-substituted phenyltrifluoromethyldiazirine. Angew Chem Int Ed Engl 2002 0.75
151 Oxidative in vitro folding of a cysteine deficient variant of the G protein-coupled neuropeptide Y receptor type 2 improves stability at high concentration. Biol Chem 2013 0.75
152 Expressed protein ligation for protein semisynthesis and engineering. Methods Mol Biol 2005 0.75
153 Matrix metalloproteinase 9 (MMP-9) mediated release of MMP-9 resistant stromal cell-derived factor 1α (SDF-1α) from surface modified polymer films. ACS Appl Mater Interfaces 2014 0.75
154 Novel modified and radiolabelled neuropeptide Y analogues to study Y-receptor subtypes. Neuropeptides 2004 0.75
155 Identification of the dimerisation interface of human interleukin-8 by IL-8-variants containing the photoactivatable amino acid benzoyl-phenylalanine. Eur Biophys J 2006 0.75
156 Fluorescence resonance energy transfer to study receptor dimerization in living cells. Methods Mol Biol 2004 0.75
157 Selective labelling of stromal cell-derived factor 1α with carboxyfluorescein to study receptor internalisation. J Pept Sci 2010 0.75
158 Synthesis and application of peptides as drug carriers. Methods Mol Biol 2009 0.75
159 Cluster properties of peptides on (100) semiconductor surfaces. Langmuir 2006 0.75
160 Proliferative effect of calcitonin gene-related peptide is induced by at least five proteins as identified by proteome profiling. Chem Biol Drug Des 2007 0.75
161 From transcription profile to expression: the signaling repertoire of the SK-N-MC neuroepithelioma cell-line. J Recept Signal Transduct Res 2004 0.75
162 Highlight: protein states with cell biological and medicinal relevance. Biol Chem 2013 0.75
163 Tuning peptide affinity for biofunctionalized surfaces. Eur J Pharm Biopharm 2013 0.75