Ichiro Hisatome

Author PubWeight™ 92.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. J Biol Chem 2008 2.09
2 Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell. Am J Physiol Heart Circ Physiol 2002 1.94
3 Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. J Am Soc Nephrol 2004 1.87
4 Appropriate use of nasal continuous positive airway pressure decreases elevated C-reactive protein in patients with obstructive sleep apnea. Chest 2009 1.75
5 Uric acid-lowering treatment with benzbromarone in patients with heart failure: a double-blind placebo-controlled crossover preliminary study. Circ Heart Fail 2009 1.73
6 Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia. Circ J 2015 1.55
7 Transient left ventricular apical ballooning in a patient with bicuspid aortic valve created a left ventricular thrombus leading to acute renal infarction. Circ J 2004 1.52
8 Electrophysiological properties of prion-positive cardiac progenitors derived from murine embryonic stem cells. Circ J 2012 1.40
9 Left atrial branches of coronary arteries; clinical implications related to linear catheter ablation for atrial fibrillation. J Interv Card Electrophysiol 2009 1.38
10 Addition of losartan to angiotensin-converting enzyme inhibitors improves insulin resistance in patients with chronic heart failure treated without β-blockers. Circ J 2010 1.38
11 Brachiocephalic vein perforation on three-dimensional computed tomography. Europace 2007 1.38
12 Hepatocyte growth factor exerts a proliferative effect on oval cells through the PI3K/AKT signaling pathway. Biochem Biophys Res Commun 2003 1.17
13 Uricosuric action of losartan via the inhibition of urate transporter 1 (URAT 1) in hypertensive patients. Am J Hypertens 2008 1.15
14 Ubiquitin-proteasome system impairment caused by a missense cardiac myosin-binding protein C mutation and associated with cardiac dysfunction in hypertrophic cardiomyopathy. J Mol Biol 2008 1.15
15 Status of endothelial dependent vasodilation in patients with hyperuricemia. Am J Cardiol 2005 1.14
16 Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout. Clin Exp Nephrol 2014 1.09
17 Roles of L-type Ca2+ and delayed-rectifier K+ currents in sinoatrial node pacemaking: insights from stability and bifurcation analyses of a mathematical model. Am J Physiol Heart Circ Physiol 2003 1.03
18 Regional difference in dynamical property of sinoatrial node pacemaking: role of na+ channel current. Biophys J 2008 0.99
19 Dynamical mechanisms of pacemaker generation in IK1-downregulated human ventricular myocytes: insights from bifurcation analyses of a mathematical model. Biophys J 2005 0.99
20 Pendrin is an iodide-specific apical porter responsible for iodide efflux from thyroid cells. J Clin Endocrinol Metab 2002 0.98
21 Uric acid induces oxidative stress and growth inhibition by activating adenosine monophosphate-activated protein kinase and extracellular signal-regulated kinase signal pathways in pancreatic β cells. Mol Cell Endocrinol 2013 0.96
22 Abnormally high expression of proteasome activator-gamma in thyroid neoplasm. J Clin Endocrinol Metab 2003 0.96
23 Allopurinol improves cardiac dysfunction after ischemia-reperfusion via reduction of oxidative stress in isolated perfused rat hearts. Circ J 2003 0.95
24 Mechanism of iodide/chloride exchange by pendrin. Endocrinology 2004 0.93
25 Hepatic differentiation of human bone marrow-derived UE7T-13 cells: Effects of cytokines and CCN family gene expression. Hepatol Res 2007 0.93
26 Allopurinol reduces neointimal hyperplasia in the carotid artery ligation model in spontaneously hypertensive rats. Hypertens Res 2006 0.92
27 Reciprocal control of hERG stability by Hsp70 and Hsc70 with implication for restoration of LQT2 mutant stability. Circ Res 2010 0.92
28 Genetic analysis of expression profile involved in retinoid metabolism in non-alcoholic fatty liver disease. Hepatol Res 2010 0.92
29 A role of Wnt/beta-catenin signals in hepatic fate specification of human umbilical cord blood-derived mesenchymal stem cells. Am J Physiol Gastrointest Liver Physiol 2007 0.91
30 Plasma endothelin-1 levels and clinical correlates in patients with chronic heart failure. J Card Fail 2003 0.91
31 Disrupted plasma membrane localization of equilibrative nucleoside transporter 2 in the chemoresistance of human pancreatic cells to gemcitabine (dFdCyd). Cancer Sci 2011 0.90
32 Effects of pacemaker currents on creation and modulation of human ventricular pacemaker: theoretical study with application to biological pacemaker engineering. Am J Physiol Heart Circ Physiol 2006 0.87
33 Impairment of ubiquitin-proteasome system by E334K cMyBPC modifies channel proteins, leading to electrophysiological dysfunction. J Mol Biol 2011 0.87
34 Roles of sarcoplasmic reticulum Ca2+ cycling and Na+/Ca2+ exchanger in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models. Am J Physiol Heart Circ Physiol 2012 0.86
35 Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins. Cardiovasc Res 2013 0.85
36 Age-related BM-MNC dysfunction hampers neovascularization. Mech Ageing Dev 2007 0.85
37 Chemical chaperone therapy: chaperone effect on mutant enzyme and cellular pathophysiology in β-galactosidase deficiency. Hum Mutat 2011 0.85
38 Analyses to clarify rich fractions in hepatic progenitor cells from human umbilical cord blood and cell fusion. Biochem Biophys Res Commun 2004 0.85
39 c-Jun N-terminal kinase activation by oxidative stress suppresses retinoid signaling through proteasomal degradation of retinoic acid receptor α protein in hepatic cells. Cancer Sci 2011 0.84
40 The status of hypertension management in Japan in 2000. Hypertens Res 2002 0.84
41 Subtype switching of T-type Ca 2+ channels from Cav3.2 to Cav3.1 during differentiation of embryonic stem cells to cardiac cell lineage. Circ J 2005 0.84
42 Proinflammatory cytokine activation is linked to apoptotic mediator, soluble Fas level in patients with chronic heart failure. Int Heart J 2012 0.84
43 Evidence for proteasomal degradation of Kv1.5 channel protein. Biochem Biophys Res Commun 2005 0.84
44 Roles of hyperpolarization-activated current If in sinoatrial node pacemaking: insights from bifurcation analysis of mathematical models. Am J Physiol Heart Circ Physiol 2010 0.83
45 Effect of the angiotensin II receptor antagonist losartan on uric acid and oxypurine metabolism in healthy subjects. Intern Med 2002 0.83
46 Detection of the novel autoantibody (anti-UACA antibody) in patients with Graves' disease. Biochem Biophys Res Commun 2004 0.83
47 Role of cysteinyl leukotrienes in the proliferation and the migration of murine vascular smooth muscle cells in vivo and in vitro. Cardiovasc Res 2007 0.83
48 Identification, isolation and characterization of HCN4-positive pacemaking cells derived from murine embryonic stem cells during cardiac differentiation. Pacing Clin Electrophysiol 2009 0.83
49 Ventricular tachycardias and dilated cardiomyopathy caused by Fabry disease. Pacing Clin Electrophysiol 2005 0.82
50 Characteristics of cardiac myxoma with constitutional signs: a multicenter study in Japan. Clin Cardiol 2002 0.82
51 Acute myocardial infarction in a patient with essential thrombocythemia: successful treatment with percutaneous transluminal coronary recanalization. Circ J 2005 0.82
52 Neurohumoral profiles in patients with hypertrophic cardiomyopathy: differences to hypertensive left ventricular hypertrophy. Circ J 2004 0.82
53 Histopathologic background for resistance to conventional catheter ablation of common atrial flutter. J Cardiovasc Electrophysiol 2004 0.82
54 Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells. Eur J Pharmacol 2008 0.81
55 Prognostic significance of exercise plasma noradrenaline levels for cardiac death in patients with mild heart failure. Circ J 2002 0.81
56 Effects of the angiotensin-converting enzyme inhibitor alacepril on exercise capacity and neurohormonal factors in patients with mild-to-moderate heart failure. Clin Exp Pharmacol Physiol 2002 0.81
57 Protective effect of edaravone against hypoxia-reoxygenation injury in rabbit cardiomyocytes. Br J Pharmacol 2004 0.81
58 Reactive oxygen species and NADPH oxidase 4 induced by transforming growth factor β1 are the therapeutic targets of polyenylphosphatidylcholine in the suppression of human hepatic stellate cell activation. Inflamm Res 2011 0.81
59 A simple risk score to predict in-hospital death of elderly patients with acute decompensated heart failure--hypoalbuminemia as an additional prognostic factor. Circ J 2009 0.80
60 Neurohormonal determinants of peak oxygen uptake in patients with chronic heart failure. Jpn Heart J 2003 0.80
61 Adipose stem cell sheets improved cardiac function in the rat myocardial infarction, but did not alter cardiac contractile responses to β-adrenergic stimulation. Biomed Res 2015 0.80
62 Effect of hyperpolarization-activated current I(f) on robustness of sinoatrial node pacemaking: theoretical study on influence of intracellular Na(+) concentration. Am J Physiol Heart Circ Physiol 2013 0.80
63 Pendrin is a novel autoantigen recognized by patients with autoimmune thyroid diseases. J Clin Endocrinol Metab 2008 0.80
64 Analysis of moricizine block of sodium current in isolated guinea-pig atrial myocytes. Atrioventricular difference of moricizine block. Vascul Pharmacol 2002 0.80
65 Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na+ channel blocker aprindine. Biochem Biophys Res Commun 2005 0.79
66 Extrinsic factors derived from mouse embryonal carcinoma cell lines maintain pluripotency of mouse embryonic stem cells through a novel signal pathway. Dev Growth Differ 2009 0.79
67 A comparative study on the effectiveness of losartan/hydrochlorothiazide and telmisartan/hydrochlorothiazide in patients with hypertension. Clin Exp Hypertens 2013 0.79
68 Heterochromatin protein 1γ overexpression in P19 embryonal carcinoma cells elicits spontaneous differentiation into the three germ layers. Biochem Biophys Res Commun 2013 0.79
69 Effect of losartan and benzbromarone on the level of human urate transporter 1 mRNA. Arzneimittelforschung 2010 0.79
70 Fenofibrate enhances neovascularization in a murine ischemic hindlimb model. J Cardiovasc Pharmacol 2009 0.79
71 Transplantation of freshly isolated adipose tissue-derived regenerative cells enhances angiogenesis in a murine model of hind limb ischemia. Biomed Res 2013 0.79
72 Usefulness of three-dimensional echocardiography in assessing right ventricular function in patients with primary pulmonary hypertension. Hypertens Res 2009 0.79
73 Iron state in association with retinoid metabolism in non-alcoholic fatty liver disease. Hepatol Res 2010 0.79
74 Status of uric acid management in hypertensive subjects. Hypertens Res 2007 0.79
75 Interleukin-6 and tumor necrosis factor-alpha levels increase in response to maximal exercise in patients with chronic heart failure. Int J Cardiol 2003 0.78
76 Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone. Eur J Pharmacol 2012 0.78
77 Giant aneurysm of the coronary sinus. J Cardiovasc Electrophysiol 2006 0.78
78 [Calcium antagonists: current and future applications based on new evidence. The mechanisms on lowering serum uric acid level by calcium channel blockers]. Clin Calcium 2010 0.78
79 Parathyroid hormone-related protein is produced in the myocardium and increased in patients with congestive heart failure. J Clin Endocrinol Metab 2002 0.78
80 Remote reperfusion lung injury is associated with AMP deaminase 3 activation and attenuated by inosine monophosphate. Circ J 2007 0.78
81 Changes of HCN gene expression and I(f) currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation. Biomed Res 2008 0.78
82 Therapeutic effect of adenoviral-mediated hepatocyte growth factor gene administration on TNBS-induced colitis in mice. Biochem Biophys Res Commun 2005 0.78
83 QRS complex widening due to loss of left bundle branch capture: pitfall of para-Hisian pacing. J Interv Card Electrophysiol 2009 0.78
84 Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice. Biomed Res 2010 0.78
85 Small extra-adrenal pheochromocytoma causing severe hypertension in an elderly patient. Hypertens Res 2006 0.78
86 Follicular thyroglobulin enhances gene expression necessary for thyroid hormone secretion. Endocr J 2015 0.78
87 Cytosolic phospholipase A2alpha contributes to blood pressure increases and endothelial dysfunction under chronic NO inhibition. Arterioscler Thromb Vasc Biol 2011 0.78
88 Catabolism of adenine nucleotides favors adenosine production following exercise in patients with chronic heart failure. J Card Fail 2006 0.78
89 Effects of azelnidipine on uric acid metabolism in patients with essential hypertension. Clin Exp Hypertens 2014 0.78
90 Long-term reliability of AAI mode pacing in patients with sinus node dysfunction and low Wenckebach block rate. Europace 2008 0.77
91 Expression of a thyroglobulin (Tg) variant in mouse kidney glomerulus. Biochem Biophys Res Commun 2009 0.77
92 Effects of cilnidipine on serum uric acid level and urinary nitrogen monoxide excretion in patients with hypertension. Clin Exp Hypertens 2012 0.77
93 L-cysteine prevents oxidation-induced block of the cardiac Na+ channel via interaction with heart-specific cysteinyl residues in the P-loop region. Circ J 2002 0.77
94 Functional stabilization of Kv1.5 protein by Hsp70 in mammalian cell lines. Biochem Biophys Res Commun 2008 0.77
95 Hepatocyte growth factor mobilizes and recruits hematopoietic progenitor cells into liver through a stem cell factor-mediated mechanism. Hepatol Res 2010 0.77
96 Inhibition of inward rectifier K+ currents by angiotensin II in rat atrial myocytes: lack of effects in cells from spontaneously hypertensive rats. Hypertens Res 2006 0.77
97 Relation between neurohormonal activation and enhanced ventilatory response to exercise in patients with chronic congestive heart failure. Am J Cardiol 2002 0.77
98 High Uric Acid Activates the ROS-AMPK Pathway, Impairs CD68 Expression and Inhibits OxLDL-Induced Foam-Cell Formation in a Human Monocytic Cell Line, THP-1. Cell Physiol Biochem 2016 0.77
99 Molecular Mechanisms Underlying Urate-Induced Enhancement of Kv1.5 Channel Expression in HL-1 Atrial Myocytes. Circ J 2015 0.76
100 Plasma levels of uridine correlate with blood pressure and indicators of myogenic purine degradation and insulin resistance in hypertensive patients. Circ J 2007 0.76
101 AMP deaminase 3 plays a critical role in remote reperfusion lung injury. Biochem Biophys Res Commun 2013 0.76
102 Autoperipheral blood mononuclear cell transplantation improved giant ulcers due to chronic arteriosclerosis obliterans. Heart Vessels 2006 0.76
103 Inhibition of beta-adrenergic signaling by intracellular AMP is independent of cell-surface adenosine receptors in rat cardiac cells. J Mol Cell Cardiol 2007 0.76
104 The cyclooxygenase-2 selective inhibitor, etodolac, but not aspirin reduces neovascularization in a murine ischemic hind limb model. Eur J Pharmacol 2009 0.76
105 Coordinate induction of AMP deaminase in human atrium with mitochondrial DNA deletion. Biochem Biophys Res Commun 2003 0.76
106 VEGF secretion by adipose tissue-derived regenerative cells is impaired under hyperglycemic conditions via glucose transporter activation and ROS increase. Biomed Res 2014 0.76
107 Effects of angiotensin II on the action potential durations of atrial myocytes in hypertensive rats. Hypertens Res 2005 0.76
108 Hyperuricemia and Atrial Fibrillation. Int Heart J 2016 0.75
109 Apoptosis induced by an uromodulin mutant C112Y and its suppression by topiroxostat. Clin Exp Nephrol 2014 0.75
110 Effects of angiotensin II type 1 receptor antagonist, losartan, on ventilatory response to exercise and neurohormonal profiles in patients with chronic heart failure. Jpn J Physiol 2004 0.75
111 Synergistic effects of autologous cell and hepatocyte growth factor gene therapy for neovascularization in a murine model of hindlimb ischemia. Am J Physiol Heart Circ Physiol 2009 0.75
112 Sweet preference, obesity and genetic polymorphism of leptin and the leptin receptor. Hypertens Res 2008 0.75
113 Expression of oxidative stress-related molecules in circulating leukocytes and urine in patients with chronic viral hepatitis. Liver Int 2006 0.75
114 Excessive purine degradation during semi-ischemic forearm test in patients with diabetes mellitus. Intern Med 2003 0.75
115 Acute secondary gastrointestinal amyloidosis in a patient with rheumatoid arthritis. Am J Med Sci 2003 0.75
116 Novel effects of extracts from poisonous mushrooms on expression and function of the human ether-a-go-go-related gene channel. Biol Pharm Bull 2011 0.75
117 Effects of a low-dose antihypertensive diuretic in combination with losartan, telmisartan, or candesartan on serum urate levels in hypertensive patients. Arzneimittelforschung 2010 0.75
118 Instability of KCNE1-D85N that causes long QT syndrome: stabilization by verapamil. Pacing Clin Electrophysiol 2014 0.75
119 [Hyperuricemia]. Nihon Naika Gakkai Zasshi 2011 0.75
120 [Idiopathic hyperuricemia with overproduction of uric acid]. Nihon Rinsho 2008 0.75
121 [How do we set the standard value of serum uric acid levels?]. Nihon Rinsho 2008 0.75
122 Current status of lipid management of hypertensive patients. Hypertens Res 2003 0.75
123 Extension of the inferior vena cava into the posteroinferior right atrium. Heart Rhythm 2006 0.75
124 Isolated autonomic cardiovascular neuropathy in a patient with primary Sjögren syndrome: a case of successful treatment with glucocorticoid. Am J Med Sci 2002 0.75
125 [Other antihyperuricemic agents]. Nihon Rinsho 2008 0.75
126 Macroreentrant atrial tachycardia with an isolated pathway mimicking focal activation on three-dimensional electroanatomical mapping. J Interv Card Electrophysiol 2007 0.75
127 Troglitazone improves cardiac function in patients with congestive heart failure. Cardiovasc Drugs Ther 2002 0.75
128 Elevated Serum Uric Acid Level Predicts Rapid Decline in Kidney Function. Am J Nephrol 2017 0.75
129 [Anti hyperuricemic agents]. Nihon Rinsho 2003 0.75
130 Developmental changes of Ni(2+) sensitivity and automaticity in Nkx2.5-positive cardiac precursor cells from murine embryonic stem cell. Circ J 2004 0.75
131 Delayed onset of beating and decreased expression of T-type Ca2+ channel in mouse ES cell-derived cardiocytes carrying human chromosome 21. Biochem Biophys Res Commun 2006 0.75
132 Removal of coronary sinus intima by a guidewire during cardiac resynchronization therapy. Pacing Clin Electrophysiol 2007 0.75
133 State-dependent blocking actions of azimilide dihydrochlo-ride (NE-10064) on human cardiac Na(+) channels. Circ J 2004 0.75
134 Enhancing effects of salicylate on quinidine-induced block of human wild type and LQT3 related mutant cardiac Na+ channels. Biomed Res 2011 0.75
135 Exact location of the branching bundle in the living heart. Pacing Clin Electrophysiol 2009 0.75
136 [Drug-induced hyperuricemia]. Nihon Rinsho 2003 0.75
137 M3 Muscarinic Receptor Signaling Stabilizes a Novel Mutant Human Ether-a-Go-Go-Related Gene Channel Protein via Phosphorylation of Heat Shock Factor 1 in Transfected Cells. Circ J 2016 0.75
138 [Abnormal mass lesion in the right atrium detected by ultrasonic echocardiography]. J Cardiol 2005 0.75
139 Can Xanthine Oxidase Inhibitors Improve Cardiac Function in Patients With Chronic Heart Failure? Int Heart J 2016 0.75