Published in Breast Cancer Res Treat on September 01, 2005
Effects of HER2 overexpression on cell signaling networks governing proliferation and migration. Mol Syst Biol (2006) 3.01
Steroid receptor coactivator-3/AIB1 promotes cell migration and invasiveness through focal adhesion turnover and matrix metalloproteinase expression. Cancer Res (2008) 1.54
Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells. Br J Cancer (2006) 1.49
Expression and function of the insulin receptor substrate proteins in cancer. Cell Commun Signal (2009) 1.35
Role of TGF-beta in proliferative vitreoretinal diseases and ROCK as a therapeutic target. Proc Natl Acad Sci U S A (2008) 1.31
Distinct molecular phenotype of inflammatory breast cancer compared to non-inflammatory breast cancer using Affymetrix-based genome-wide gene-expression analysis. Br J Cancer (2007) 1.17
Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells. Breast Cancer Res (2010) 1.14
Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. PLoS Biol (2009) 1.10
Cixutumumab. Expert Opin Investig Drugs (2009) 1.09
Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development. Dev Biol (2007) 1.04
Annexin A6 contributes to the invasiveness of breast carcinoma cells by influencing the organization and localization of functional focal adhesions. Exp Cell Res (2010) 1.00
IRS2 is a candidate driver oncogene on 13q34 in colorectal cancer. Int J Exp Pathol (2013) 0.98
PPAR-γ agonists and their effects on IGF-I receptor signaling: Implications for cancer. PPAR Res (2009) 0.96
Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling. J Neurosci (2009) 0.96
Cyclin-dependent kinase 5 promotes pancreatic β-cell survival via Fak-Akt signaling pathways. Diabetes (2011) 0.94
Molecular biology of head and neck cancer: risks and pathways. Hematol Oncol Clin North Am (2008) 0.91
Combination of anti-IGF-1R antibody A12 and ionizing radiation in upper respiratory tract cancers. Int J Radiat Oncol Biol Phys (2010) 0.88
P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin. Exp Cell Res (2006) 0.83
Progesterone receptor-B regulation of insulin-like growth factor-stimulated cell migration in breast cancer cells via insulin receptor substrate-2. Mol Cancer Res (2008) 0.82
Roles of osteoclasts and bone-derived IGFs in the survival and growth of human breast cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice. Clin Exp Metastasis (2008) 0.82
Human Cortical Neural Stem Cells Expressing Insulin-Like Growth Factor-I: A Novel Cellular Therapy for Alzheimer's Disease. Stem Cells Transl Med (2016) 0.81
G-Protein Inwardly Rectifying Potassium Channel 1 (GIRK1) Knockdown Decreases Beta-Adrenergic, MAP Kinase and Akt Signaling in the MDA-MB-453 Breast Cancer Cell Line. Breast Cancer (Auckl) (2008) 0.78
The role of EphB4 and IGF-IR expression in breast cancer cells. Int J Clin Exp Pathol (2015) 0.76
Insulin-like growth factor 1 receptor expression and IGF1R 3129G > T polymorphism are associated with response to neoadjuvant chemotherapy in breast cancer patients: results from the NEOZOTAC trial (BOOG 2010-01). Breast Cancer Res (2016) 0.75
ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells. Stem Cell Res Ther (2015) 0.75
Diabetes and cancer: a consensus report. Diabetes Care (2010) 6.71
APOBEC3B is an enzymatic source of mutation in breast cancer. Nature (2013) 5.18
Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins. J Clin Invest (2008) 4.95
Diabetes and cancer: a consensus report. CA Cancer J Clin (2010) 3.95
A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription. Cancer Cell (2010) 3.47
Effect of an implantable gentamicin-collagen sponge on sternal wound infections following cardiac surgery: a randomized trial. JAMA (2010) 3.39
Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells. Cancer Cell (2004) 2.91
Functional mapping - how to map and study the genetic architecture of dynamic complex traits. Nat Rev Genet (2006) 2.87
Right vertical infra-axillary mini-incision for repair of simple congenital heart defects: a matched-pair analysis. Eur J Cardiothorac Surg (2012) 2.72
Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501. Proc Natl Acad Sci U S A (2008) 2.70
Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias. Cancer Cell (2003) 2.54
Disrupting insulin-like growth factor signaling as a potential cancer therapy. Mol Cancer Ther (2007) 2.50
Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling. Cancer Cell (2011) 2.45
Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation. J Clin Invest (2006) 2.28
Randomized controlled trial of weight training and lymphedema in breast cancer survivors. J Clin Oncol (2006) 2.27
Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence. Cell Stem Cell (2008) 2.08
A role for LIM kinase in cancer invasion. Proc Natl Acad Sci U S A (2003) 2.03
WISP3 is a novel tumor suppressor gene of inflammatory breast cancer. Oncogene (2002) 2.02
Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2. J Pharmacol Exp Ther (2008) 1.98
Endoscopic thoracic sympathectomy for palmar hyperhidrosis: a randomized control trial comparing T3 and T2-4 ablation. Ann Thorac Surg (2008) 1.97
Neoadjuvant chemotherapy of locally advanced breast cancer: predicting response with in vivo (1)H MR spectroscopy--a pilot study at 4 T. Radiology (2004) 1.95
Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. N Engl J Med (2010) 1.89
Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database. Mol Cancer Ther (2009) 1.83
Safety and efficacy of weight training in recent breast cancer survivors to alter body composition, insulin, and insulin-like growth factor axis proteins. Cancer Epidemiol Biomarkers Prev (2005) 1.81
Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability. Am J Pathol (2002) 1.79
In vivo quantification of choline compounds in the breast with 1H MR spectroscopy. Magn Reson Med (2003) 1.76
High-throughput single nucleotide polymorphism genotyping using nanofluidic Dynamic Arrays. BMC Genomics (2009) 1.76
A general framework for analyzing the genetic architecture of developmental characteristics. Genetics (2004) 1.74
Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis. Cancer Res (2002) 1.73
Identification of an endogenous ligand bound to a native orphan nuclear receptor. PLoS One (2009) 1.70
Vitamin K2 regulation of bone homeostasis is mediated by the steroid and xenobiotic receptor SXR. J Biol Chem (2003) 1.69
Stepping out of the flow: capillary extravasation in cancer metastasis. Clin Exp Metastasis (2007) 1.68
Crosstalk between IGF1R and estrogen receptor signaling in breast cancer. J Mammary Gland Biol Neoplasia (2008) 1.63
Sensitive quantitation of minimal residual disease in chronic myeloid leukemia using nanofluidic digital polymerase chain reaction assay. Leuk Lymphoma (2011) 1.61
Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin. Cancer Res (2007) 1.61
A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I. Cancer Res (2003) 1.61
Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines. Proc Natl Acad Sci U S A (2011) 1.56
Minimizing endoscopic thoracic sympathectomy for primary palmar hyperhidrosis: guided by palmar skin temperature and laser Doppler blood flow. Ann Thorac Surg (2009) 1.56
Prevention of chylothorax complicating extensive esophageal resection by mass ligation of thoracic duct: a random control study. Ann Thorac Surg (2011) 1.55
RhoC-GTPase is a novel tissue biomarker associated with biologically aggressive carcinomas of the breast. Breast Cancer Res Treat (2005) 1.49
Hawai'i's role to increase public participation in health research. Hawaii Med J (2008) 1.48
Complete genome sequence of the nitrogen-fixing and rhizosphere-associated bacterium Pseudomonas stutzeri strain DSM4166. J Bacteriol (2011) 1.46
Metabolite quantification and high-field MRS in breast cancer. NMR Biomed (2009) 1.45
Adenosquamous carcinoma of the jejunum. J Gastroenterol (2003) 1.43
Synovial sarcoma is a stem cell malignancy. Stem Cells (2010) 1.42
Functional mapping of quantitative trait loci underlying growth trajectories using a transform-both-sides logistic model. Biometrics (2004) 1.40
Clinical significance of detecting elevated serum DcR3/TR6/M68 in malignant tumor patients. Int J Cancer (2003) 1.40
A dominant negative type I insulin-like growth factor receptor inhibits metastasis of human cancer cells. J Biol Chem (2003) 1.38
Novel AroA with high tolerance to glyphosate, encoded by a gene of Pseudomonas putida 4G-1 isolated from an extremely polluted environment in China. Appl Environ Microbiol (2005) 1.38
Continuous inhibition of MAPK signaling promotes the early osteoblastic differentiation and mineralization of the extracellular matrix. J Bone Miner Res (2002) 1.37
Long-term mortality of patients undergoing cardiac catheterization for ST-elevation and non-ST-elevation myocardial infarction. Circulation (2009) 1.36
First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity. Circulation (2006) 1.35
Effects of weight training on quality of life in recent breast cancer survivors: the Weight Training for Breast Cancer Survivors (WTBS) study. Cancer (2006) 1.35
Identification of cell-of-origin breast tumor subtypes in inflammatory breast cancer by gene expression profiling. Breast Cancer Res Treat (2005) 1.34
Complete genome sequence of the type strain Pseudomonas stutzeri CGMCC 1.1803. J Bacteriol (2011) 1.32
STAT6 mediates interleukin-4 growth inhibition in human breast cancer cells. Neoplasia (2002) 1.32
Eliminating spurious lipid sidebands in 1H MRS of breast lesions. Magn Reson Med (2002) 1.30
A study of the irradiation temperature coefficient for L-alanine and DL-alanine dosemeters. Radiat Prot Dosimetry (2006) 1.30
Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer. Breast Cancer Res Treat (2005) 1.29
Rho GTPases in PC-3 prostate cancer cell morphology, invasion and tumor cell diapedesis. Clin Exp Metastasis (2008) 1.27
The IGF pathway regulates ERα through a S6K1-dependent mechanism in breast cancer cells. Mol Endocrinol (2011) 1.27
Type I insulin-like growth factor receptor as a therapeutic target in cancer. Cancer Res (2005) 1.27
Type I collagen receptor (alpha 2 beta 1) signaling promotes the growth of human prostate cancer cells within the bone. Cancer Res (2006) 1.24
Acquired resistance to tamoxifen is associated with loss of the type I insulin-like growth factor receptor: implications for breast cancer treatment. Cancer Res (2012) 1.24
Identification of several proteins involved in regulation of sperm motility by proteomic analysis. Fertil Steril (2006) 1.24
Trastuzumab and interleukin-2 in HER2-positive metastatic breast cancer: a pilot study. Clin Cancer Res (2003) 1.22
Inhibitors of insulin-like growth factor signaling: a therapeutic approach for breast cancer. J Mammary Gland Biol Neoplasia (2006) 1.22
Type I collagen receptor (alpha2beta1) signaling promotes prostate cancer invasion through RhoC GTPase. Neoplasia (2008) 1.22
MicroRNAs link estrogen receptor alpha status and Dicer levels in breast cancer. Horm Cancer (2010) 1.18
The Notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression. Mol Cell Biol (2007) 1.17
A structural model of the constitutive androstane receptor defines novel interactions that mediate ligand-independent activity. Mol Cell Biol (2002) 1.17
A simple disc degeneration model induced by percutaneous needle puncture in the rat tail. Spine (Phila Pa 1976) (2008) 1.16
Down-regulation of insulin receptor by antibodies against the type I insulin-like growth factor receptor: implications for anti-insulin-like growth factor therapy in breast cancer. Cancer Res (2006) 1.15
Adding in vivo quantitative 1H MR spectroscopy to improve diagnostic accuracy of breast MR imaging: preliminary results of observer performance study at 4.0 T. Radiology (2005) 1.14
Angiogenesis, lymphangiogenesis, growth pattern, and tumor emboli in inflammatory breast cancer: a review of the current knowledge. Cancer (2010) 1.14
Nitrogen fixation genetics and regulation in a Pseudomonas stutzeri strain associated with rice. Microbiology (2003) 1.14
Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease. Circulation (2008) 1.14
Proteomic analysis of proteins involved in spermiogenesis in mouse. J Proteome Res (2010) 1.13
Oropharyngeal dysphagia in infants and children with infantile Pompe disease. Dysphagia (2009) 1.13
Killing the second messenger: targeting loss of cell cycle control in endocrine-resistant breast cancer. Endocr Relat Cancer (2011) 1.12
Structure of the murine constitutive androstane receptor complexed to androstenol: a molecular basis for inverse agonism. Mol Cell (2004) 1.11
Imaging in breast cancer: Magnetic resonance spectroscopy. Breast Cancer Res (2005) 1.11
Characterization of the biosynthetic genes for 10,11-dehydrocurvularin, a heat shock response-modulating anticancer fungal polyketide from Aspergillus terreus. Appl Environ Microbiol (2013) 1.11
Iron activates NF-kappaB in Kupffer cells. Am J Physiol Gastrointest Liver Physiol (2002) 1.10
Sequencing of type I insulin-like growth factor receptor inhibition affects chemotherapy response in vitro and in vivo. Clin Cancer Res (2009) 1.10
Water-fat MRI for assessing changes in bone marrow composition due to radiation and chemotherapy in gynecologic cancer patients. J Magn Reson Imaging (2013) 1.08
Targeting insulin and insulin-like growth factor signaling in breast cancer. J Mammary Gland Biol Neoplasia (2012) 1.08
Genetic organization of genes encoding phenol hydroxylase, benzoate 1,2-dioxygenase alpha subunit and its regulatory proteins in Acinetobacter calcoaceticus PHEA-2. Curr Microbiol (2003) 1.08
Selective activation of insulin receptor substrate-1 and -2 in pleural mesothelioma cells: association with distinct malignant phenotypes. Cancer Res (2004) 1.07
IGF-I secreted by osteoblasts acts as a potent chemotactic factor for osteoblasts. Bone (2008) 1.07
Insulin-like growth factor-I receptor expression regulates neuroblastoma metastasis to bone. Cancer Res (2006) 1.07
Insulin-like growth factor-I and cancer risk. Growth Horm IGF Res (2004) 1.06
Rho-regulatory proteins in breast cancer cell motility and invasion. Breast Cancer Res Treat (2004) 1.06
Phospholipid transfer protein deficiency protects circulating lipoproteins from oxidation due to the enhanced accumulation of vitamin E. J Biol Chem (2002) 1.06
Regulation of pancreatic cancer cell migration and invasion by RhoC GTPase and caveolin-1. Mol Cancer (2005) 1.05
Motility response to insulin-like growth factor-I (IGF-I) in MCF-7 cells is associated with IRS-2 activation and integrin expression. Breast Cancer Res Treat (2004) 1.05