Published in Birth Defects Res C Embryo Today on September 01, 2005
A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis. Dev Biol (2008) 2.09
Directed differentiation of human embryonic stem cells toward chondrocytes. Nat Biotechnol (2010) 1.72
Regulation of chondrogenesis and chondrocyte differentiation by stress. J Clin Invest (2008) 1.53
Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints. Dev Biol (2007) 1.42
Lineage tracing using matrilin-1 gene expression reveals that articular chondrocytes exist as the joint interzone forms. Dev Biol (2007) 1.30
Vertebrate skeletogenesis. Curr Top Dev Biol (2010) 1.30
Indian hedgehog roles in post-natal TMJ development and organization. J Dent Res (2010) 1.22
Transcription factor ERG and joint and articular cartilage formation during mouse limb and spine skeletogenesis. Dev Biol (2007) 1.21
Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. Development (2009) 1.18
Regulation of articular chondrocyte proliferation and differentiation by indian hedgehog and parathyroid hormone-related protein in mice. Arthritis Rheum (2008) 1.17
Mechanobiology of embryonic skeletal development: Insights from animal models. Birth Defects Res C Embryo Today (2010) 1.16
Identification of a Prg4-expressing articular cartilage progenitor cell population in mice. Arthritis Rheumatol (2015) 1.13
Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity. EMBO J (2009) 1.13
Roles of β-catenin signaling in phenotypic expression and proliferation of articular cartilage superficial zone cells. Lab Invest (2011) 1.13
Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol (2010) 1.08
Cell sources for the regeneration of articular cartilage: the past, the horizon and the future. Int J Exp Pathol (2012) 1.06
Mechanical influences on morphogenesis of the knee joint revealed through morphological, molecular and computational analysis of immobilised embryos. PLoS One (2011) 1.05
Versican facilitates chondrocyte differentiation and regulates joint morphogenesis. J Biol Chem (2010) 1.05
Effect of aging on cellular mechanotransduction. Ageing Res Rev (2009) 1.04
Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes. Arthritis Res Ther (2012) 1.02
Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling. Ann N Y Acad Sci (2007) 1.01
Smurf2 induces degradation of GSK-3beta and upregulates beta-catenin in chondrocytes: a potential mechanism for Smurf2-induced degeneration of articular cartilage. Exp Cell Res (2009) 0.99
JAWS coordinates chondrogenesis and synovial joint positioning. Development (2008) 0.99
Beta-catenin, cartilage, and osteoarthritis. Ann N Y Acad Sci (2010) 0.99
Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways. Genes Dev (2014) 0.97
Early effects of embryonic movement: 'a shot out of the dark'. J Anat (2006) 0.97
Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol (2010) 0.96
Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice. Bone (2013) 0.94
Cartilage to bone transitions in health and disease. J Endocrinol (2013) 0.93
Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation. Development (2015) 0.92
Time-dependent processes in stem cell-based tissue engineering of articular cartilage. Stem Cell Rev (2012) 0.92
Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses. Dev Biol (2013) 0.91
Genesis and morphogenesis of limb synovial joints and articular cartilage. Matrix Biol (2014) 0.89
BMPRIA mediated signaling is essential for temporomandibular joint development in mice. PLoS One (2014) 0.88
Fetal ACL fibroblasts exhibit enhanced cellular properties compared with adults. Clin Orthop Relat Res (2008) 0.87
Hox11 genes establish synovial joint organization and phylogenetic characteristics in developing mouse zeugopod skeletal elements. Development (2010) 0.87
Dlx5 Is a cell autonomous regulator of chondrocyte hypertrophy in mice and functionally substitutes for Dlx6 during endochondral ossification. PLoS One (2009) 0.86
The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation. Dev Biol (2011) 0.86
RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance. Arthritis Rheum (2013) 0.85
Joint shape morphogenesis precedes cavitation of the developing hip joint. J Anat (2013) 0.85
Interleukin 6 mediates selected effects of Notch in chondrocytes. Osteoarthritis Cartilage (2013) 0.84
Cell-based articular cartilage repair: the link between development and regeneration. Osteoarthritis Cartilage (2014) 0.84
Osteophyte formation and matrix mineralization in a TMJ osteoarthritis mouse model are associated with ectopic hedgehog signaling. Matrix Biol (2016) 0.84
SOX11 contributes to the regulation of GDF5 in joint maintenance. BMC Dev Biol (2013) 0.83
Osteoarthritis pathogenesis: a review of molecular mechanisms. Calcif Tissue Int (2014) 0.83
Notch Signaling and the Skeleton. Endocr Rev (2016) 0.82
Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin. Dev Biol (2014) 0.82
Proteolytic cleavage of versican during limb joint development. Anat Rec (Hoboken) (2010) 0.81
GDF-5 can act as a context-dependent BMP-2 antagonist. BMC Biol (2015) 0.81
Chondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint development. Histochem Cell Biol (2012) 0.81
Endochondral Growth Defect and Deployment of Transient Chondrocyte Behaviors Underlie Osteoarthritis Onset in a Natural Murine Model. Arthritis Rheumatol (2016) 0.80
Is the spinal motion segment a diarthrodial polyaxial joint: what a nice nucleus like you doing in a joint like this? Bone (2011) 0.80
Gene expression profiling reveals similarities between the spatial architectures of postnatal articular and growth plate cartilage. PLoS One (2014) 0.80
Articular Cartilage: Structural and Developmental Intricacies and Questions. Curr Osteoporos Rep (2015) 0.79
TASR-1 regulates alternative splicing of collagen genes in chondrogenic cells. Biochem Biophys Res Commun (2007) 0.79
Finite element modelling predicts changes in joint shape and cell behaviour due to loss of muscle strain in jaw development. J Biomech (2015) 0.79
Regulation of α5 and αV Integrin Expression by GDF-5 and BMP-7 in Chondrocyte Differentiation and Osteoarthritis. PLoS One (2015) 0.78
Synovial joints: from development to homeostasis. Curr Osteoporos Rep (2015) 0.78
Effects of normal and abnormal loading conditions on morphogenesis of the prenatal hip joint: application to hip dysplasia. J Biomech (2015) 0.76
Versican knockdown reduces interzone area during early stages of chick synovial joint development. Anat Rec (Hoboken) (2011) 0.76
Fibulin-3 in joint aging and osteoarthritis pathogenesis. Arthritis Rheumatol (2016) 0.75
Atypical molecular profile for joint development in the avian costal joint. Dev Dyn (2010) 0.75
Reintegration of the regenerated and the remaining tissues during joint regeneration in the newt Cynops pyrrhogaster. Regeneration (Oxf) (2015) 0.75
The role of Nkx3.2 in chondrogenesis. Front Biol (Beijing) (2014) 0.75
Signaling networks in joint development. Dev Dyn (2016) 0.75
Differential effects of altered patterns of movement and strain on joint cell behaviour and skeletal morphogenesis. Osteoarthritis Cartilage (2016) 0.75
First evidence of a bipartite medial cuneiform in the hominin fossil record: a case report from the Early Pleistocene site of Dmanisi. J Anat (2010) 0.75
Recapitulation of physiological spatiotemporal signals promotes in vitro formation of phenotypically stable human articular cartilage. Proc Natl Acad Sci U S A (2017) 0.75
Endogenous DKK1 and FRZB Regulate Chondrogenesis and Hypertrophy in Three-Dimensional Cultures of Human Chondrocytes and Human Mesenchymal Stem Cells. Stem Cells Dev (2016) 0.75
Functional joint regeneration is achieved using reintegration mechanism in Xenopus laevis. Regeneration (Oxf) (2016) 0.75
Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists. Nat Med (2011) 2.40
A distinct cohort of progenitor cells participates in synovial joint and articular cartilage formation during mouse limb skeletogenesis. Dev Biol (2008) 2.09
Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification. J Biol Chem (2005) 2.04
Conditional Kif3a ablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis. Development (2007) 1.97
Temporomandibular joint formation and condyle growth require Indian hedgehog signaling. Dev Dyn (2007) 1.70
The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis. Dev Biol (2002) 1.68
Wnt/beta-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration. Lab Invest (2008) 1.58
Increase in plasma levels of adiponectin after administration of anti-tumor necrosis factor agents in patients with rheumatoid arthritis. J Rheumatol (2008) 1.54
Rheumatoid arthritis complicated with acute interstitial pneumonia induced by leflunomide as an adverse reaction. Intern Med (2004) 1.53
Sustained elevation of interleukin-33 in sera and synovial fluids from patients with rheumatoid arthritis non-responsive to anti-tumor necrosis factor: possible association with persistent IL-1β signaling and a poor clinical response. Rheumatol Int (2011) 1.52
Fluorodeoxyglucose positron emission tomography/computed tomography for diagnostic imaging in relapsing polychondritis with atypical manifestations. J Clin Rheumatol (2013) 1.46
Runx2 deficiency in chondrocytes causes adipogenic changes in vitro. J Cell Sci (2004) 1.44
Sjögren's syndrome associated with chronic hepatitis C, severe thrombocytopenia, hypertrophic cardiomyopathy, and diabetes mellitus. Intern Med (2005) 1.38
Cellular and molecular mechanisms of synovial joint and articular cartilage formation. Ann N Y Acad Sci (2006) 1.23
Selective expansion of a monocyte subset expressing the CD11c dendritic cell marker in the Yaa model of systemic lupus erythematosus. Arthritis Rheum (2005) 1.21
Transcription factor ERG and joint and articular cartilage formation during mouse limb and spine skeletogenesis. Dev Biol (2007) 1.21
Increased levels of interleukin 33 in sera and synovial fluid from patients with active rheumatoid arthritis. J Rheumatol (2009) 1.20
Sonic hedgehog is involved in osteoblast differentiation by cooperating with BMP-2. J Cell Physiol (2002) 1.16
Wnt/beta-catenin and retinoic acid receptor signaling pathways interact to regulate chondrocyte function and matrix turnover. J Biol Chem (2009) 1.16
Transplanted bone marrow mononuclear cells and MSCs impart clinical benefit to children with osteogenesis imperfecta through different mechanisms. Blood (2012) 1.14
Roles of β-catenin signaling in phenotypic expression and proliferation of articular cartilage superficial zone cells. Lab Invest (2011) 1.13
Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse. Dev Biol (2009) 1.11
Indian and sonic hedgehogs regulate synchondrosis growth plate and cranial base development and function. Dev Biol (2006) 1.10
Transient activation of Wnt/{beta}-catenin signaling induces abnormal growth plate closure and articular cartilage thickening in postnatal mice. Am J Pathol (2009) 1.10
Pneumocystis jiroveci pneumonia in patients with rheumatoid arthritis treated with infliximab: a retrospective review and case-control study of 21 patients. Arthritis Rheum (2009) 1.09
Heparan sulfate in skeletal development, growth, and pathology: the case of hereditary multiple exostoses. Dev Dyn (2013) 1.08
Nocardia arthritidis sp. nov., a new pathogen isolated from a patient with rheumatoid arthritis in Japan. J Clin Microbiol (2004) 1.07
Effects of FTY720 in MRL-lpr/lpr mice: therapeutic potential in systemic lupus erythematosus. J Rheumatol (2002) 1.05
The critical role of the epidermal growth factor receptor in endochondral ossification. J Bone Miner Res (2011) 1.04
Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study. Mod Rheumatol (2014) 1.01
Synovial joint formation during mouse limb skeletogenesis: roles of Indian hedgehog signaling. Ann N Y Acad Sci (2007) 1.01
Oxytocin deficiency impairs maternal skeletal remodeling. Biochem Biophys Res Commun (2009) 1.00
Inhibition of ectopic bone formation by a selective retinoic acid receptor alpha-agonist: a new therapy for heterotopic ossification? J Orthop Res (2010) 0.98
Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones. Bone (2011) 0.98
Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol (2010) 0.96
Indian hedgehog and syndecans-3 coregulate chondrocyte proliferation and function during chick limb skeletogenesis. Dev Dyn (2004) 0.96
Antiangiogenic treatment delays chondrocyte maturation and bone formation during limb skeletogenesis. J Bone Miner Res (2002) 0.95
Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice. Bone (2013) 0.94
Retinoid signaling regulates CTGF expression in hypertrophic chondrocytes with differential involvement of MAP kinases. J Bone Miner Res (2004) 0.93
Expression and roles of connective tissue growth factor in Meckel's cartilage development. Dev Dyn (2004) 0.93
Expression, gene regulation, and roles of Fisp12/CTGF in developing tooth germs. Dev Dyn (2002) 0.91
Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: a mechanism likely deranged in Hereditary Multiple Exostoses. Dev Biol (2013) 0.91
Expression of Indian Hedgehog, BMP-4 and Noggin in craniosynostosis induced by fetal constraint. Ann Plast Surg (2007) 0.90
Expression and role of Lhx8 in murine tooth development. Arch Histol Cytol (2003) 0.90
Sonic hedgehog regulates osteoblast function by focal adhesion kinase signaling in the process of fracture healing. PLoS One (2013) 0.89
Intervertebral disc development is regulated by Wnt/β-catenin signaling. Spine (Phila Pa 1976) (2011) 0.89
Syndecan-3 is a selective regulator of chondrocyte proliferation. J Biol Chem (2002) 0.89
Effective and safe administration of tocilizumab to a patient with rheumatoid arthritis on haemodialysis. Rheumatol Int (2010) 0.88
Loss of β-catenin induces multifocal periosteal chondroma-like masses in mice. Am J Pathol (2012) 0.87
Small GTPase protein Rac-1 is activated with maturation and regulates cell morphology and function in chondrocytes. Exp Cell Res (2008) 0.86
Glucocorticoid and cyclosporine refractory adult onset Still's disease successfully treated with tocilizumab. Clin Rheumatol (2009) 0.86
Successful treatment of a patient with rheumatoid arthritis and IgA-κ multiple myeloma with tocilizumab. Intern Med (2011) 0.85
Distribution of slow-cycling cells in epiphyseal cartilage and requirement of β-catenin signaling for their maintenance in growth plate. J Orthop Res (2014) 0.85
Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and -independent pathways. J Biol Chem (2013) 0.84
The balancing act of transcription factors C-1-1 and Runx2 in articular cartilage development. Biochem Biophys Res Commun (2005) 0.83
Sonic hedgehog functions as a mitogen during bell stage of odontogenesis. Connect Tissue Res (2003) 0.83
Syndecan-3: a cell-surface heparan sulfate proteoglycan important for chondrocyte proliferation and function during limb skeletogenesis. J Bone Miner Metab (2005) 0.83
Endogenous retinoids in mammalian growth plate cartilage: analysis and roles in matrix homeostasis and turnover. J Biol Chem (2010) 0.82
Prognostic indicators related to death in patients with Pneumocystis pneumonia associated with collagen vascular diseases. Rheumatol Int (2009) 0.81
Phenotype profile of a genetic mouse model for Muenke syndrome. Childs Nerv Syst (2012) 0.80
Nonthermal atmospheric pressure plasma enhances mouse limb bud survival, growth, and elongation. Tissue Eng Part A (2014) 0.80
Endothelial Erg expression is required for embryogenesis and vascular integrity. Organogenesis (2015) 0.79
Sonic hedgehog signaling promotes growth of oral squamous cell carcinoma cells associated with bone destruction. Oral Oncol (2011) 0.79
Steroid-refractory severe hepatic failure in adult onset Still's disease responding to cyclosporine. Clin Rheumatol (2008) 0.79
Production of thromboxane A2 and prostaglandin i2 affected by interaction of heat aggregated IgG, endothelial cells, and platelets in lupus nephritis. J Rheumatol (2002) 0.79
Rapidly aggravated Mycobacterium avium infection in a patient with rheumatoid arthritis treated with infliximab. Mod Rheumatol (2005) 0.79
Repeated local implantation of autologous peripheral blood mononuclear cells for the treatment of ischaemic digits in patients with connective tissue diseases. Rheumatology (Oxford) (2010) 0.79
Novel hedgehog agonists promote osteoblast differentiation in mesenchymal stem cells. J Cell Physiol (2015) 0.78
Epitope-dependent inhibition of T cell activation by the Ea transgene: an explanation for transgene-mediated protection from murine lupus. J Immunol (2004) 0.78
High serum levels of menatetrenone in male patients with ossification of the posterior longitudinal ligament. Spine (Phila Pa 1976) (2003) 0.78
Marked pneumatosis cystoides intestinalis in a patient with mixed connective tissue disease. J Rheumatol (2006) 0.78
Interleukin-18 in adult-onset Still's disease: treatment target or disease activity indicator? Intern Med (2012) 0.77
[Clinical features in patients with polymyalgia rheumatica]. Nihon Rinsho Meneki Gakkai Kaishi (2009) 0.77
Retreatment efficacy and safety of tocilizumab in patients with rheumatoid arthritis in recurrence (RESTORE) study. Mod Rheumatol (2014) 0.77
Antisynthetase syndrome associated with long-standing rheumatoid arthritis. Rheumatol Int (2010) 0.77
Successful treatment with very low-dose etanercept in a patient with etanercept-induced liver dysfunction. Rheumatol Int (2010) 0.77
Polyarthritis induced by nonepisodic angioedema associated with eosinophilia. Rheumatol Int (2008) 0.77
Bone morphogenetic protein 4 is involved in cusp formation in molar tooth germ of mice. Eur J Oral Sci (2002) 0.77
Parathyroid hormone-related peptide regulates matrix metalloproteinase-13 gene expression in bone metastatic breast cancer cells. Anticancer Res (2010) 0.76
Posterior ischemic optic neuropathy in a patient with granulomatosis with polyangiitis (Wegener's). Rheumatol Int (2012) 0.76
Aspects of interleukin-8 gene expression by gingival and dermal fibroblasts stimulated with interleukin-1beta or tumour necrosis factor alpha. J Int Acad Periodontol (2004) 0.76
Abrupt development of sarcoidosis with a prodromal increase in plasma osteopontin in a patient with rheumatoid arthritis during treatment with etanercept. J Rheumatol (2010) 0.76
Is Chlamydia pneumoniae the causative agent of microscopic polyangiitis? Nephrol Dial Transplant (2010) 0.75
Comment on: Churg-Strauss syndrome: a retrospective study of 11 cases from a single center in Japan. Int J Rheum Dis (2011) 0.75
Semaphorin 4D inhibits collagen synthesis of rat pulp-derived cells. Arch Oral Biol (2007) 0.75
Moderate incidence of prior rheumatoid arthritis in patients with polymyositis and dermatomyositis. Clin Rheumatol (2011) 0.75
DRUG-INDUCED LUPUS CAUSED BY LONG TERM MINOCYCLINE TREATMENT FOR ACNE VULGARIS. Arerugi (2015) 0.75
Acute acalculous cholecystitis in systemic sclerosis. Rheumatol Int (2009) 0.75
Treatment of rheumatoid arthritis with tacrolimus: tacrolimus-induced urticaria. J Clin Rheumatol (2009) 0.75