Published in Am J Physiol Renal Physiol on September 27, 2005
The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease. Pharmacol Rev (2007) 6.79
A glimpse of various pathogenetic mechanisms of diabetic nephropathy. Annu Rev Pathol (2011) 2.51
Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase. Proc Natl Acad Sci U S A (2008) 2.06
Oxidative stress in diabetic nephropathy. Curr Med Chem (2010) 1.70
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. Am J Pathol (2007) 1.55
Redox control of renal function and hypertension. Antioxid Redox Signal (2008) 1.45
1,25-Dihydroxyvitamin D3 suppresses high glucose-induced angiotensinogen expression in kidney cells by blocking the NF-{kappa}B pathway. Am J Physiol Renal Physiol (2009) 1.31
The importance of the intrarenal renin-angiotensin system. Nat Clin Pract Nephrol (2008) 1.15
Long-term therapeutic effect of vitamin D analog doxercalciferol on diabetic nephropathy: strong synergism with AT1 receptor antagonist. Am J Physiol Renal Physiol (2009) 1.13
Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model. Am J Physiol Regul Integr Comp Physiol (2011) 1.08
Enzymatic processing of angiotensin peptides by human glomerular endothelial cells. Am J Physiol Renal Physiol (2012) 1.04
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy. Pediatr Nephrol (2008) 0.96
The use of lineage tracing to study kidney injury and regeneration. Nat Rev Nephrol (2015) 0.95
Therapeutic targets in focal and segmental glomerulosclerosis. Curr Opin Nephrol Hypertens (2008) 0.94
Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II-mediated podocyte apoptosis. Kidney Int (2011) 0.92
Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria. Kidney Int (2015) 0.86
Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes. Inflamm Res (2012) 0.83
Renin-angiotensin-aldosterone system-mediated redox effects in chronic kidney disease. Transl Res (2009) 0.83
Angiotensin II receptor blocker attenuates intrarenal renin-angiotensin-system and podocyte injury in rats with myocardial infarction. PLoS One (2013) 0.81
The intrarenal generation of angiotensin II is required for experimental hypertension. Curr Opin Pharmacol (2015) 0.78
A case report of adrenocorticotropic hormone to treat recurrent focal segmental glomerular sclerosis post-transplantation and biomarker monitoring. Front Med (Lausanne) (2015) 0.77
Mineralocorticoid Receptor Blocker Protects against Podocyte-Dependent Glomerulosclerosis. Nephron Extra (2012) 0.77
C3G overexpression in glomerular epithelial cells during anti-GBM-induced glomerulonephritis. Kidney Int (2008) 0.77
Transgenic Strategies to Study Podocyte Loss and Regeneration. Stem Cells Int (2015) 0.76
Advanced glycation end-products reduce podocyte adhesion by activating the renin-angiotensin system and increasing integrin-linked kinase. Exp Ther Med (2013) 0.75
Intrarenal Angiotensin-Converting Enzyme: the Old and the New. Curr Hypertens Rep (2017) 0.75
Genomics. Genome project standards in a new era of sequencing. Science (2009) 7.72
Molecular weights of coliphages and coliphage DNA. 3. Contour length and molecular weight of DNA from bacteriophages T4, T5 and T7, and from bovine papilloma virus. J Mol Biol (1970) 7.20
Construction and properties of an integrable plasmid for Bacillus subtilis. J Bacteriol (1983) 7.12
Immunosuppression for progressive membranous nephropathy: a UK randomised controlled trial. Lancet (2013) 7.03
A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression. J Am Soc Nephrol (2002) 6.48
Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy. N Engl J Med (2011) 6.34
Everolimus in patients with autosomal dominant polycystic kidney disease. N Engl J Med (2010) 5.50
Simplified quantitative electron microscopy of biopolymers. Biopolymers (1970) 5.37
Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaea. Proc Natl Acad Sci U S A (2010) 4.12
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice. J Clin Invest (2010) 3.44
Electron microscopy of size and shape of viral DNA in solutions of different ionic strengths. J Mol Biol (1967) 3.16
Insulin signaling to the glomerular podocyte is critical for normal kidney function. Cell Metab (2010) 3.05
Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. J Clin Invest (2011) 2.90
Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling. Mol Cell Biol (2003) 2.69
Patient perception of bodily functions in multiple sclerosis: gait and visual function are the most valuable. Mult Scler (2008) 2.44
Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome. Blood (2009) 2.33
Antiphospholipase A2 receptor antibody titer and subclass in idiopathic membranous nephropathy. J Am Soc Nephrol (2012) 2.21
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A (2006) 2.16
Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors. J Cell Sci (2008) 2.09
Prorenin receptor is essential for normal podocyte structure and function. J Am Soc Nephrol (2011) 2.08
WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing. Cancer Cell (2011) 2.06
Functional evidence that vascular endothelial growth factor may act as an autocrine factor on human podocytes. Am J Physiol Renal Physiol (2003) 2.00
Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy. J Am Soc Nephrol (2013) 1.94
C-reactive protein makes human endothelium stiff and tight. Hypertension (2010) 1.91
The podocyte cytoskeleton--key to a functioning glomerulus in health and disease. Nat Rev Nephrol (2011) 1.86
NEPH1 defines a novel family of podocin interacting proteins. FASEB J (2002) 1.85
Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis. Ann Rheum Dis (2012) 1.81
Human podocytes adhere to the KRGDS motif of the alpha3alpha4alpha5 collagen IV network. J Am Soc Nephrol (2008) 1.81
'Brain attack'--aneurysmal subarachnoid haemorrhage: death due to delayed diagnosis. J R Coll Physicians Lond (1997) 1.76
Organic cation transporter 2 mediates cisplatin-induced oto- and nephrotoxicity and is a target for protective interventions. Am J Pathol (2010) 1.76
Carnosine as a protective factor in diabetic nephropathy: association with a leucine repeat of the carnosinase gene CNDP1. Diabetes (2005) 1.75
ADCK4 mutations promote steroid-resistant nephrotic syndrome through CoQ10 biosynthesis disruption. J Clin Invest (2013) 1.74
Identification of binding sites for the 86-kilodalton IE2 protein of human cytomegalovirus within an IE2-responsive viral early promoter. J Virol (1994) 1.73
Cisplatin nephrotoxicity is critically mediated via the human organic cation transporter 2. Am J Pathol (2005) 1.73
Molecular basis of the functional podocin-nephrin complex: mutations in the NPHS2 gene disrupt nephrin targeting to lipid raft microdomains. Hum Mol Genet (2003) 1.70
Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Sci Signal (2010) 1.70
Shunt implantation: reducing the incidence of shunt infection. J Neurosurg (1992) 1.69
Glomerular endothelial glycocalyx constitutes a barrier to protein permeability. J Am Soc Nephrol (2007) 1.69
Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy. Nephrol Dial Transplant (2009) 1.68
Effects of dietary inclusion of probiotic and synbiotic on growth performance, organ weights, and intestinal histomorphology of broiler chickens. Poult Sci (2009) 1.68
The immunogenic glycoprotein gp35-37 of human herpesvirus 8 is encoded by open reading frame K8.1. J Virol (1998) 1.66
Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome. Clin J Am Soc Nephrol (2013) 1.64
Interferon-beta reduces proteinuria in experimental glomerulonephritis. J Am Soc Nephrol (2007) 1.63
Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. Kidney Int (2009) 1.62
Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties. J Am Soc Nephrol (2004) 1.59
The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus. J Mol Biol (2001) 1.58
High phosphate directly affects endothelial function by downregulating annexin II. Kidney Int (2012) 1.57
Nephrin is critical for the action of insulin on human glomerular podocytes. Diabetes (2007) 1.55
Metabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans. Drug Metab Dispos (2009) 1.53
The diameter of coronary arteries in infants and children without heart disease. Eur J Pediatr (1989) 1.51
Use of identification cards by underage youth to purchase tobacco. JAMA (2001) 1.51
The soluble VEGF receptor sFlt1 contributes to endothelial dysfunction in CKD. J Am Soc Nephrol (2009) 1.50
The human glomerular podocyte is a novel target for insulin action. Diabetes (2005) 1.49
Mechanisms of angiotensin II signaling on cytoskeleton of podocytes. J Mol Med (Berl) (2008) 1.46
Comparative promoter analysis allows de novo identification of specialized cell junction-associated proteins. Proc Natl Acad Sci U S A (2006) 1.43
Regulation of nephrin gene by the Ets transcription factor, GA-binding protein. Nephrol Dial Transplant (2012) 1.43
Migration of cardiac neural crest cells in Splotch embryos. Development (2000) 1.43
Prolonged akinetic mutism due to multiple sclerosis. J Neuropsychiatry Clin Neurosci (1995) 1.40
Safe paediatric neurosurgery 2001. Br J Neurosurg (2002) 1.40
VEGF regulates local inhibitory complement proteins in the eye and kidney. J Clin Invest (2016) 1.39
The open conformation of a Pseudomonas lipase. Structure (1997) 1.39
CCL1-CCR8 interactions: an axis mediating the recruitment of T cells and Langerhans-type dendritic cells to sites of atopic skin inflammation. J Immunol (2005) 1.37
KIBRA modulates directional migration of podocytes. J Am Soc Nephrol (2008) 1.36
Regulatory mechanisms in carbohydrate metabolism. IX. Stimulation of aerobic glycolysis by energy-linked ion transport and inhibition by dextran sulfate. J Biol Chem (1973) 1.35
Nephrin-signature molecule of the glomerular podocyte? J Pathol (2010) 1.35
Co-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formation. Am J Pathol (2002) 1.34
Denaturation map of bacteriophage T7 DNA and direction of DNA transcription. J Mol Biol (1972) 1.32
Regular superstructures of purified DNA in ethanolic solutions. J Mol Biol (1973) 1.31
The molecular and functional phenotype of glomerular podocytes reveals key features of contractile smooth muscle cells. Am J Physiol Renal Physiol (2008) 1.31
Dilemmas in the management of atrial fibrillation in chronic kidney disease. J Am Soc Nephrol (2008) 1.30
Vascular endothelial growth factor and nephrin interact and reduce apoptosis in human podocytes. Am J Physiol Renal Physiol (2004) 1.29
Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Arterioscler Thromb Vasc Biol (2001) 1.29
Cell death in rheumatoid arthritis. Apoptosis (2009) 1.29
Increased inorganic phosphate induces human endothelial cell apoptosis in vitro. Am J Physiol Renal Physiol (2008) 1.28
A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function. Blood (2012) 1.28
mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes. Am J Physiol Renal Physiol (2008) 1.27
Statin-sensitive endocytosis of albumin by glomerular podocytes. Am J Physiol Renal Physiol (2006) 1.27
Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins. J Cell Sci (2011) 1.27
New insights into the function of the Wilms tumor suppressor gene WT1 in podocytes. Am J Physiol Renal Physiol (2008) 1.26
Nephrotic plasma alters slit diaphragm-dependent signaling and translocates nephrin, Podocin, and CD2 associated protein in cultured human podocytes. J Am Soc Nephrol (2005) 1.26
Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy. Nephrol Dial Transplant (2010) 1.26
A snapshot of a transition state analogue of a novel thermophilic esterase belonging to the subfamily of mammalian hormone-sensitive lipase. J Mol Biol (2000) 1.25
Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive. J Neurosci (2002) 1.25
Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis. J Biol Chem (2009) 1.24