PubRank

Leona D Samson

Author PubWeight™ 94.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Systematic discovery of in vivo phosphorylation networks. Cell 2007 6.94
2 Standardizing global gene expression analysis between laboratories and across platforms. Nat Methods 2005 6.23
3 Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping. Mol Cancer Res 2002 5.42
4 A systems approach to mapping DNA damage response pathways. Science 2006 3.55
5 DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J Clin Invest 2008 3.17
6 Balancing repair and tolerance of DNA damage caused by alkylating agents. Nat Rev Cancer 2012 2.52
7 Activation of inflammation/NF-kappaB signaling in infants born to arsenic-exposed mothers. PLoS Genet 2007 2.19
8 AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo. Nat Struct Mol Biol 2005 1.96
9 Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses. J Biol Chem 2003 1.95
10 Global network analysis of phenotypic effects: protein networks and toxicity modulation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 2004 1.90
11 The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation. J Clin Invest 2003 1.82
12 Hot spots for modulating toxicity identified by genomic phenotyping and localization mapping. Mol Cell 2004 1.81
13 Human AlkB homolog ABH8 Is a tRNA methyltransferase required for wobble uridine modification and DNA damage survival. Mol Cell Biol 2010 1.53
14 Genome-wide responses to DNA-damaging agents. Annu Rev Microbiol 2005 1.48
15 Apoptotic signaling in response to a single type of DNA lesion, O(6)-methylguanine. Mol Cell 2004 1.37
16 Rat liver sinusoidal endothelial cells survive without exogenous VEGF in 3D perfused co-cultures with hepatocytes. FASEB J 2007 1.35
17 AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA. Cancer Res 2008 1.30
18 Combined experimental and computational analysis of DNA damage signaling reveals context-dependent roles for Erk in apoptosis and G1/S arrest after genotoxic stress. Mol Syst Biol 2012 1.20
19 Polymorphisms in DNA double-strand break repair genes and skin cancer risk. Cancer Res 2004 1.20
20 Genomic predictors of interindividual differences in response to DNA damaging agents. Genes Dev 2008 1.20
21 Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proc Natl Acad Sci U S A 2002 1.20
22 Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase. J Biol Chem 2004 1.20
23 3-Methyladenine DNA glycosylase-deficient Aag null mice display unexpected bone marrow alkylation resistance. Cancer Res 2002 1.18
24 Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG). Biochemistry 2009 1.16
25 Integrated molecular analysis indicates undetectable change in DNA damage in mice after continuous irradiation at ~ 400-fold natural background radiation. Environ Health Perspect 2012 1.15
26 AlkB mystery solved: oxidative demethylation of N1-methyladenine and N3-methylcytosine adducts by a direct reversal mechanism. Trends Biochem Sci 2003 1.11
27 Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice. Proc Natl Acad Sci U S A 2009 1.09
28 Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase. Mol Cell 2010 1.07
29 Multiplexed DNA repair assays for multiple lesions and multiple doses via transcription inhibition and transcriptional mutagenesis. Proc Natl Acad Sci U S A 2014 1.06
30 Network responses to DNA damaging agents. DNA Repair (Amst) 2004 1.05
31 Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. Toxicol Sci 2007 1.04
32 DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts. PLoS One 2010 1.03
33 The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner. PLoS One 2011 1.01
34 O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo. Proc Natl Acad Sci U S A 2009 0.99
35 DNA repair is indispensable for survival after acute inflammation. J Clin Invest 2012 0.96
36 Genetic association and functional studies of major polymorphic variants of MGMT. DNA Repair (Amst) 2007 0.95
37 Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis. Genes Dev 2013 0.95
38 Base excision repair. Adv Exp Med Biol 2005 0.93
39 Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 2011 0.91
40 New immunoaffinity-LC-MS/MS methodology reveals that Aag null mice are deficient in their ability to clear 1,N6-etheno-deoxyadenosine DNA lesions from lung and liver in vivo. DNA Repair (Amst) 2004 0.91
41 Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice. Carcinogenesis 2006 0.91
42 Genetic susceptibility to chronic hepatitis is inherited codominantly in Helicobacter hepaticus-infected AB6F1 and B6AF1 hybrid male mice, and progression to hepatocellular carcinoma is linked to hepatic expression of lipogenic genes and immune function-associated networks. Infect Immun 2008 0.91
43 Direct repair of 3,N(4)-ethenocytosine by the human ALKBH2 dioxygenase is blocked by the AAG/MPG glycosylase. DNA Repair (Amst) 2011 0.91
44 Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1. PLoS Genet 2013 0.91
45 Structural basis for the inhibition of human alkyladenine DNA glycosylase (AAG) by 3,N4-ethenocytosine-containing DNA. J Biol Chem 2011 0.90
46 Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase. Biochemistry 2011 0.88
47 Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis. Carcinogenesis 2010 0.87
48 Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates. PLoS One 2007 0.86
49 Comparative modeling and analysis of microfluidic and conventional DNA microarrays. Anal Biochem 2005 0.86
50 Polymorphisms in O6-methylguanine DNA methyltransferase and breast cancer risk. Pharmacogenet Genomics 2006 0.86
51 Substrate specificity and sequence-dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag). DNA Repair (Amst) 2008 0.85
52 Anc1, a protein associated with multiple transcription complexes, is involved in postreplication repair pathway in S. cerevisiae. PLoS One 2008 0.85
53 3-Methyladenine DNA glycosylase is important for cellular resistance to psoralen interstrand cross-links. DNA Repair (Amst) 2008 0.84
54 Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae. Nucleic Acids Res 2013 0.84
55 A rapid survival assay to measure drug-induced cytotoxicity and cell cycle effects. DNA Repair (Amst) 2011 0.84
56 O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation. Integr Biol (Camb) 2012 0.84
57 The protein degradation response of Saccharomyces cerevisiae to classical DNA-damaging agents. Chem Res Toxicol 2007 0.83
58 Molecular biology: A fix for RNA. Nature 2003 0.82
59 The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA. BMC Genomics 2006 0.82
60 Microfluidic genome-wide profiling of intrinsic electrical properties in Saccharomyces cerevisiae. Lab Chip 2013 0.81
61 Oxanine DNA glycosylase activities in mammalian systems. DNA Repair (Amst) 2007 0.80
62 Substrate binding pocket residues of human alkyladenine-DNA glycosylase critical for methylating agent survival. DNA Repair (Amst) 2008 0.80
63 Identification of novel human damage response proteins targeted through yeast orthology. PLoS One 2012 0.80
64 Alkyladenine DNA glycosylase (AAG) localizes to mitochondria and interacts with mitochondrial single-stranded binding protein (mtSSB). DNA Repair (Amst) 2013 0.80
65 Reversing DNA damage with a directional bias. Nat Struct Mol Biol 2004 0.80
66 Alkyladenine DNA glycosylase (Aag) in somatic hypermutation and class switch recombination. DNA Repair (Amst) 2007 0.80
67 Mutational-reporter transgenes rescued from mice lacking either Mgmt, or both Mgmt and Msh6 suggest that O6-alkylguanine-induced miscoding does not contribute to the spontaneous mutational spectrum. Oncogene 2004 0.80
68 Genomic phenotyping by barcode sequencing broadly distinguishes between alkylating agents, oxidizing agents, and non-genotoxic agents, and reveals a role for aromatic amino acids in cellular recovery after quinone exposure. PLoS One 2013 0.76
69 Survival and tumorigenesis in O6-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure. Mutagenesis 2008 0.76
70 Single-cell analysis of ribonucleotide reductase transcriptional and translational response to DNA damage. Mol Cell Biol 2012 0.76
71 On the 50th anniversary of solving the structure of DNA. Environ Health Perspect 2003 0.75