Published in Mutat Res on March 23, 2005
Basic mechanics of DNA methylation and the unique landscape of the DNA methylome in metal-induced carcinogenesis. Crit Rev Toxicol (2013) 0.97
JNK inhibitor SP600125 promotes the formation of polymerized tubulin, leading to G2/M phase arrest, endoreduplication, and delayed apoptosis. Exp Mol Med (2009) 0.87
Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon. Br J Haematol (2009) 0.84
Cysteine string protein-alpha prevents activity-dependent degeneration in GABAergic synapses. J Neurosci (2010) 1.51
Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients. J Nat Prod (2005) 1.42
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci U S A (2013) 1.23
Guanidine-reactive agent phenylglyoxal induces DNA damage and cancer cell death. Pharmacol Rep (2012) 0.96
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair. Nucleic Acids Res (2013) 0.95
Roles of DNA topoisomerases in chromosome segregation and mitosis. Mutat Res (2003) 0.89
A comparative study of genotoxic effects of anti-topoisomerase II drugs ICRF-193 and bufalin in Chinese hamster ovary cells. Mutat Res (2002) 0.89
Empyema necessitatis revisited. Eur J Dermatol (2009) 0.88
Toward a comprehensive model for induced endoreduplication. Life Sci (2004) 0.88
Induction of endoreduplication by topoisomerase II catalytic inhibitors. Mutagenesis (2003) 0.88
Evaluation of genotoxic effects of heavy metals and arsenic in wild nestling white storks (Ciconia ciconia) and black kites (Milvus migrans) from southwestern Spain after a mining accident. Environ Toxicol Chem (2006) 0.87
Anti-tumour activity of Digitalis purpurea L. subsp. heywoodii. Planta Med (2003) 0.86
The coffee constituent chlorogenic acid induces cellular DNA damage and formation of topoisomerase I- and II-DNA complexes in cells. J Agric Food Chem (2012) 0.85
Bufalin influences the repair of X-ray-induced DNA breaks in Chinese hamster cells. DNA Repair (Amst) (2003) 0.85
Cytotoxic effect of Plantago spp. on cancer cell lines. J Ethnopharmacol (2003) 0.84
DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin. Mutagenesis (2009) 0.82
Tea flavanols inhibit cell growth and DNA topoisomerase II activity and induce endoreduplication in cultured Chinese hamster cells. Mutat Res (2008) 0.80
Genotoxicity detected in wild mice living in a highly polluted wetland area in south western Spain. Environ Pollut (2007) 0.80
Cisplatin-induced endoreduplication in CHO cells: DNA damage and inhibition of topoisomerase II. Mutat Res (2006) 0.80
A 4 year follow-up analysis of genotoxic damage in birds of the Doñana area (south west Spain) in the wake of the 1998 mining waste spill. Mutagenesis (2004) 0.79
Alpha, beta-unsaturated lactones 2-furanone and 2-pyrone induce cellular DNA damage, formation of topoisomerase I- and II-DNA complexes and cancer cell death. Toxicol Lett (2013) 0.79
Modulation of radiation response by inhibiting topoisomerase II catalytic activity. Mutat Res (2006) 0.78
High yield of endoreduplication induced by ICRF-193: a topoisomerase II catalytic inhibitor. Mutat Res (2002) 0.77
Digitoxin, at concentrations commonly found in the plasma of cardiac patients, antagonizes etoposide and idarubicin activity in K562 leukemia cells. Leuk Res (2006) 0.77
Protection of halogenated DNA from strand breakage and sister-chromatid exchange induced by the topoisomerase I inhibitor camptothecin. Mutat Res (2007) 0.77
Chromosomal radiosensitivity in patients with multiple sclerosis. Mutat Res (2013) 0.77
Endoreduplication induced in cultured Chinese hamster cells by different anti-topoisomerase II chemicals. Evidence for the essential contribution of the enzyme to chromosome segregation. Mutat Res (2005) 0.76
The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II. Mutat Res (2010) 0.76
The nature of DNA plays a role in chromosome segregation: endoreduplication in halogen-substituted chromosomes. DNA Repair (Amst) (2003) 0.75
The DNA topoisomerase II catalytic inhibitor merbarone is genotoxic and induces endoreduplication. Mutat Res (2012) 0.75
Halogen substitution of DNA protects from poisoning of topoisomerase II that results in DNA double-strand breaks. DNA Repair (Amst) (2006) 0.75
DNA topoisomerase activities in Chinese hamster radiosensitive mutants after X-ray treatment. Cell Biol Int (2002) 0.75
The high rate of endoreduplication in the repair deficient CHO mutant EM9 parallels a reduced level of methylated deoxycytidine in DNA. Mutat Res (2008) 0.75
The mycotoxin ochratoxin A inhibits DNA topoisomerase II and induces polyploidy in cultured CHO cells. Toxicol In Vitro (2009) 0.75
Cytotoxicity and mitotic alterations induced by non-genotoxic lithium salts in CHO cells in vitro. Toxicol In Vitro (2009) 0.75