Published in Am J Physiol Renal Physiol on October 04, 2005
Connective tissue growth factor promotes fibrosis downstream of TGFbeta and IL-6 in chronic cardiac allograft rejection. Am J Transplant (2009) 1.59
How does TGF-β mediate tubulointerstitial fibrosis? Semin Nephrol (2012) 1.14
High glucose-induced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factor-beta1. Am J Pathol (2007) 1.10
Transcription factors Krüppel-like factor 6 and peroxisome proliferator-activated receptor-{gamma} mediate high glucose-induced thioredoxin-interacting protein. Am J Pathol (2009) 0.96
Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes. J Cell Commun Signal (2010) 0.94
Activation of JNK signaling mediates connective tissue growth factor expression and scar formation in corneal wound healing. PLoS One (2012) 0.94
Hypoxia in human trophoblasts stimulates the expression and secretion of connective tissue growth factor. Endocrinology (2008) 0.93
State of the art in intravesical therapy for lower urinary tract symptoms. Rev Urol (2010) 0.89
Ligand-dependent actions of the vitamin D receptor are required for activation of TGF-β signaling during the inflammatory response to cutaneous injury. Endocrinology (2012) 0.88
Plumbagin ameliorates diabetic nephropathy via interruption of pathways that include NOX4 signalling. PLoS One (2013) 0.87
PPAR-gamma agonists inhibit TGF-beta1-induced chemokine expression in human tubular epithelial cells. Acta Pharmacol Sin (2008) 0.86
Monocytes conditioned media stimulate fibronectin expression and spreading of inflammatory breast cancer cells in three-dimensional culture: A mechanism mediated by IL-8 signaling pathway. Cell Commun Signal (2012) 0.82
Versican is upregulated in circulating monocytes in patients with systemic sclerosis and amplifies a CCL2-mediated pathogenic loop. Arthritis Res Ther (2013) 0.81
Fenugreek Prevents the Development of STZ-Induced Diabetic Nephropathy in a Rat Model of Diabetes. Evid Based Complement Alternat Med (2014) 0.77
Cytokines in chronic kidney disease: potential link of MCP-1 and dyslipidemia in glomerular diseases. Pediatr Nephrol (2012) 0.76
A randomized, controlled trial of early versus late initiation of dialysis. N Engl J Med (2010) 10.33
Cost-effectiveness of initiating dialysis early: a randomized controlled trial. Am J Kidney Dis (2011) 2.62
The (Pro)renin receptor: site-specific and functional linkage to the vacuolar H+-ATPase in the kidney. Hypertension (2009) 2.47
Demographics and concomitant disorders in heart failure. Lancet (2003) 2.30
Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage. J Biol Chem (2002) 2.19
Overexpression of Krüppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity. Oncogene (2003) 2.11
Independent and additive impact of blood pressure control and angiotensin II receptor blockade on renal outcomes in the irbesartan diabetic nephropathy trial: clinical implications and limitations. J Am Soc Nephrol (2005) 1.96
The 2012 Canadian hypertension education program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol (2012) 1.86
The 2013 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. Can J Cardiol (2013) 1.85
Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions. Proc Natl Acad Sci U S A (2007) 1.82
Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy. J Am Soc Nephrol (2005) 1.67
Circulating bone morphogenetic protein-7 and transforming growth factor-β1 are better predictors of renal end points in patients with type 2 diabetes mellitus. Kidney Int (2012) 1.63
Mast cell infiltration and chemokine expression in progressive renal disease. Kidney Int (2003) 1.61
Urotensin II: a new player in vascular and myocardial disease? Clin Sci (Lond) (2003) 1.59
The 2010 Canadian Hypertension Education Program recommendations for the management of hypertension: part 2 - therapy. Can J Cardiol (2010) 1.44
The 2009 Canadian Hypertension Education Program recommendations for the management of hypertension: Part 2--therapy. Can J Cardiol (2009) 1.42
The Initiating Dialysis Early and Late (IDEAL) study: study rationale and design. Perit Dial Int (2004) 1.40
The 2011 Canadian Hypertension Education Program recommendations for the management of hypertension: blood pressure measurement, diagnosis, assessment of risk, and therapy. Can J Cardiol (2011) 1.38
Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppel-like factor. Am J Physiol Gastrointest Liver Physiol (2003) 1.29
Protein malnutrition and hypoalbuminemia as predictors of vascular events and mortality in ESRD. Am J Kidney Dis (2004) 1.29
The renal cortical fibroblast in renal tubulointerstitial fibrosis. Int J Biochem Cell Biol (2005) 1.27
Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts. J Am Soc Nephrol (2005) 1.26
Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the IDEAL trial. Perit Dial Int (2012) 1.25
Cardiometabolic risk in Canada: a detailed analysis and position paper by the cardiometabolic risk working group. Can J Cardiol (2011) 1.24
Novel therapies blocking the renin-angiotensin-aldosterone system in the management of hypertension and related disorders. J Hypertens (2007) 1.23
Transforming growth factor-beta/connective tissue growth factor axis in the kidney. Int J Biochem Cell Biol (2007) 1.23
Expression, localization, and function of the thioredoxin system in diabetic nephropathy. J Am Soc Nephrol (2009) 1.22
Erythropoiesis-stimulating agent hyporesponsiveness. Nephrology (Carlton) (2007) 1.19
Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy. Am J Pathol (2004) 1.18
Direct actions of urotensin II on the heart: implications for cardiac fibrosis and hypertrophy. Circ Res (2003) 1.18
The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin-associated hemolytic uremic syndrome in humans and mice. J Clin Invest (2012) 1.18
Hypertension in people with type 2 diabetes: Update on pharmacologic management. Can Fam Physician (2011) 1.17
Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism. Am J Pathol (2011) 1.17
COX-2 inhibition and retinal angiogenesis in a mouse model of retinopathy of prematurity. Invest Ophthalmol Vis Sci (2003) 1.16
Inhibition of protein kinase C-beta by ruboxistaurin preserves cardiac function and reduces extracellular matrix production in diabetic cardiomyopathy. Circ Heart Fail (2009) 1.16
Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension. Diabetes (2003) 1.15
Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism. PLoS One (2010) 1.13
Inhibition of the epidermal growth factor receptor preserves podocytes and attenuates albuminuria in experimental diabetic nephropathy. Nephrology (Carlton) (2011) 1.12
Expression of the slit-diaphragm protein, nephrin, in experimental diabetic nephropathy: differing effects of anti-proteinuric therapies. Nephrol Dial Transplant (2002) 1.11
High glucose-induced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factor-beta1. Am J Pathol (2007) 1.10
Are beta-blockers as efficacious in patients with diabetes mellitus as in patients without diabetes mellitus who have chronic heart failure? A meta-analysis of large-scale clinical trials. Am Heart J (2003) 1.10
Blockade of KCa3.1 ameliorates renal fibrosis through the TGF-β1/Smad pathway in diabetic mice. Diabetes (2013) 1.10
Role of Kruppel-like factor 6 in transforming growth factor-beta1-induced epithelial-mesenchymal transition of proximal tubule cells. Am J Physiol Renal Physiol (2008) 1.07
PKC-beta1 mediates glucose-induced Akt activation and TGF-beta1 upregulation in mesangial cells. J Am Soc Nephrol (2009) 1.07
Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells. J Biol Chem (2004) 1.06
Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta. Cardiovasc Res (2005) 1.04
CTGF and chronic kidney fibrosis. Front Biosci (Schol Ed) (2009) 1.04
The expression of NF-kappaB, Ki-67 and MMP-9 in CCOT, DGCT and GCOC. Oral Oncol (2008) 1.04
Glandular odontogenic cyst in China: report of 12 cases and immunohistochemical study. J Oral Pathol Med (2006) 1.03
Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol (2010) 1.03
Vitamin D supplementation and bone mineral density in early postmenopausal women. Am J Clin Nutr (2003) 1.02
Epidermal growth factor receptor inhibition attenuates early kidney enlargement in experimental diabetes. Kidney Int (2004) 1.02
Transforming growth factor-beta1 differentially mediates fibronectin and inflammatory cytokine expression in kidney tubular cells. Am J Physiol Renal Physiol (2006) 1.02
Expressions of nuclear factor kappaB, inducible nitric oxide synthase, and vascular endothelial growth factor in adenoid cystic carcinoma of salivary glands: correlations with the angiogenesis and clinical outcome. Clin Cancer Res (2005) 1.02
PKC-alpha-mediated remodeling of the actin cytoskeleton is involved in constitutive albumin uptake by proximal tubule cells. Am J Physiol Renal Physiol (2005) 1.01
Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction. J Mol Cell Cardiol (2005) 1.00
Association of increased ligand cyclophilin A and receptor CD147 with hypoxia, angiogenesis, metastasis and prognosis of tongue squamous cell carcinoma. Histopathology (2012) 0.99
ClC-5: a chloride channel with multiple roles in renal tubular albumin uptake. Int J Biochem Cell Biol (2005) 0.99
The renin-angiotensin system influences ocular endothelial cell proliferation in diabetes: transgenic and interventional studies. Am J Pathol (2003) 0.99
Transcriptional profiling of the cell cycle checkpoint gene krüppel-like factor 4 reveals a global inhibitory function in macromolecular biosynthesis. Gene Expr (2006) 0.98
Allelic depletion of grem1 attenuates diabetic kidney disease. Diabetes (2009) 0.97
Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines. J Biol Chem (2003) 0.97
Progression of tubulointerstitial injury by osteopontin-induced macrophage recruitment in advanced diabetic nephropathy of transgenic (mRen-2)27 rats. Nephrol Dial Transplant (2002) 0.96
Transcription factors Krüppel-like factor 6 and peroxisome proliferator-activated receptor-{gamma} mediate high glucose-induced thioredoxin-interacting protein. Am J Pathol (2009) 0.96
The role of Sgk-1 in the upregulation of transport proteins by PPAR-{gamma} agonists in human proximal tubule cells. Nephrol Dial Transplant (2008) 0.96
Identification and management of cardiometabolic risk in Canada: a position paper by the cardiometabolic risk working group (executive summary). Can J Cardiol (2011) 0.96
Tranilast attenuates structural and functional aspects of renal injury in the remnant kidney model. J Am Soc Nephrol (2004) 0.95
Renal protection in diabetes: lessons from ONTARGET. Cardiovasc Diabetol (2010) 0.95
The expression of E-cadherin at the invasive tumor front of oral squamous cell carcinoma: immunohistochemical and RT-PCR analysis with clinicopathological correlation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.95
High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule. Kidney Int (2005) 0.95
Effects on protein kinase C-beta inhibition on glomerular vascular endothelial growth factor expression and endothelial cells in advanced experimental diabetic nephropathy. Am J Physiol Renal Physiol (2007) 0.95
Molecular changes in proximal tubule function in diabetes mellitus. Clin Exp Pharmacol Physiol (2004) 0.95
Clear cell carcinoma, not otherwise specified, of salivary glands: a clinicopathologic study of 4 cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2008) 0.95
Fluorescent microangiography is a novel and widely applicable technique for delineating the renal microvasculature. PLoS One (2011) 0.94
Myoepithelial carcinoma of intraoral minor salivary glands: a clinicopathological study of 7 cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2010) 0.94
Direct observation of ion distributions near electrodes in ionic polymer actuators containing ionic liquids. Sci Rep (2013) 0.94
Early-outgrowth bone marrow cells attenuate renal injury and dysfunction via an antioxidant effect in a mouse model of type 2 diabetes. Diabetes (2012) 0.94
Slug is a key mediator of hypoxia induced cadherin switch in HNSCC: correlations with poor prognosis. Oral Oncol (2013) 0.94
Drug insight: thiazolidinediones and diabetic nephropathy--relevance to renoprotection. Nat Clin Pract Nephrol (2005) 0.93
The endothelium in diabetic nephropathy. Semin Nephrol (2012) 0.93
Isolation, propagation and characterization of primary tubule cell culture from human kidney. Nephrology (Carlton) (2007) 0.92
Gingival squamous cell carcinoma in young patients: report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.91
Increased expression of urotensin II and urotensin II receptor in human diabetic nephropathy. Am J Kidney Dis (2004) 0.91
KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis. Nephrol Dial Transplant (2013) 0.90
Calcifications in clear cell mucoepidermoid carcinomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 0.90
Urinary transforming growth factor-beta excretion in patients with hypertension, type 2 diabetes, and elevated albumin excretion rate: effects of angiotensin receptor blockade and sodium restriction. Diabetes Care (2002) 0.89
Tranilast attenuates diastolic dysfunction and structural injury in experimental diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol (2007) 0.89
Hypertension revisited. Can Fam Physician (2012) 0.88