Published in J Am Soc Nephrol on February 02, 2005
Hypotension, lipodystrophy, and insulin resistance in generalized PPARgamma-deficient mice rescued from embryonic lethality. J Clin Invest (2007) 1.85
Telmisartan provides better renal protection than valsartan in a rat model of metabolic syndrome. Am J Hypertens (2011) 1.44
The Role of PPARs in Lung Fibrosis. PPAR Res (2007) 1.37
hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists. J Am Soc Nephrol (2005) 1.31
Phase I trial of rosiglitazone in FSGS: I. Report of the FONT Study Group. Clin J Am Soc Nephrol (2008) 0.97
Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts. Br J Pharmacol (2008) 0.95
Antifibrotic effects of pioglitazone on the kidney in a rat model of type 2 diabetes mellitus. Nephrol Dial Transplant (2009) 0.94
The Nuclear Receptor PPARgamma as a Therapeutic Target for Cerebrovascular and Brain Dysfunction in Alzheimer's Disease. Front Aging Neurosci (2010) 0.93
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonists attenuate the profibrotic response induced by TGF-beta1 in renal interstitial fibroblasts. Mediators Inflamm (2007) 0.92
Lack of the serum and glucocorticoid-inducible kinase SGK1 attenuates the volume retention after treatment with the PPARgamma agonist pioglitazone. Pflugers Arch (2008) 0.91
Antifibrotic effect by activation of peroxisome proliferator-activated receptor-gamma in corneal fibroblasts. Mol Vis (2009) 0.90
PPARgamma agonist and angiotensin II receptor antagonist ameliorate renal tubulointerstitial fibrosis. J Korean Med Sci (2009) 0.88
Relaxin signaling activates peroxisome proliferator-activated receptor gamma. Mol Cell Endocrinol (2009) 0.86
Pioglitazone attenuates vascular fibrosis in spontaneously hypertensive rats. PPAR Res (2012) 0.85
Peroxisome proliferator-activated receptor gamma agonist reduces the severity of post-ERCP pancreatitis in rats. World J Gastroenterol (2006) 0.84
Rosiglitazone prevents high glucose-induced vascular endothelial growth factor and collagen IV expression in cultured mesangial cells. Exp Diabetes Res (2009) 0.84
Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor γ agonist improve vascular function and decrease renal injury in hypertensive obese rats. Exp Biol Med (Maywood) (2012) 0.82
MicroRNA-27a Induces Mesangial Cell Injury by Targeting of PPARγ, and its In Vivo Knockdown Prevents Progression of Diabetic Nephropathy. Sci Rep (2016) 0.81
Peroxisome proliferator-activated receptors in lung cancer. PPAR Res (2007) 0.81
Peroxisome proliferator-activated receptor activating hypoglycemic effect of Gardenia jasminoides Ellis aqueous extract and improvement of insulin sensitivity in steroid induced insulin resistant rats. BMC Complement Altern Med (2014) 0.81
Activation of PPARs α, β/δ, and γ Impairs TGF-β1-Induced Collagens' Production and Modulates the TIMP-1/MMPs Balance in Three-Dimensional Cultured Chondrocytes. PPAR Res (2010) 0.80
PPARγ and chronic kidney disease. Pediatr Nephrol (2010) 0.80
Therapeutics in renal disease: the road ahead for antiproliferative targets. Nephron Exp Nephrol (2005) 0.78
Combined Effects of PPAR γ Agonists and Epidermal Growth Factor Receptor Inhibitors in Human Proximal Tubule Cells. PPAR Res (2013) 0.77
Troglitazone induces extracellular matrix and cytoskeleton remodeling in mouse collecting duct cells. J Biomed Biotechnol (2012) 0.77
Renal tubular epithelium-targeted peroxisome proliferator-activated receptor-γ maintains the epithelial phenotype and antagonizes renal fibrogenesis. Oncotarget (2016) 0.75
DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms. An Bras Dermatol (2017) 0.75
Comparative RNA-Seq transcriptome analyses reveal distinct metabolic pathways in diabetic nerve and kidney disease. J Cell Mol Med (2017) 0.75
A randomized, controlled trial of early versus late initiation of dialysis. N Engl J Med (2010) 10.33
Cost-effectiveness of initiating dialysis early: a randomized controlled trial. Am J Kidney Dis (2011) 2.62
Circulating bone morphogenetic protein-7 and transforming growth factor-β1 are better predictors of renal end points in patients with type 2 diabetes mellitus. Kidney Int (2012) 1.63
The Initiating Dialysis Early and Late (IDEAL) study: study rationale and design. Perit Dial Int (2004) 1.40
Protein malnutrition and hypoalbuminemia as predictors of vascular events and mortality in ESRD. Am J Kidney Dis (2004) 1.29
Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2. J Biol Chem (2004) 1.27
The renal cortical fibroblast in renal tubulointerstitial fibrosis. Int J Biochem Cell Biol (2005) 1.27
Effect of timing of dialysis commencement on clinical outcomes of patients with planned initiation of peritoneal dialysis in the IDEAL trial. Perit Dial Int (2012) 1.25
Transforming growth factor-beta/connective tissue growth factor axis in the kidney. Int J Biochem Cell Biol (2007) 1.23
Expression, localization, and function of the thioredoxin system in diabetic nephropathy. J Am Soc Nephrol (2009) 1.22
Erythropoiesis-stimulating agent hyporesponsiveness. Nephrology (Carlton) (2007) 1.19
Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2. J Biol Chem (2007) 1.15
Cytoskeletal anchoring of GLAST determines susceptibility to brain damage: an identified role for GFAP. J Biol Chem (2007) 1.13
High glucose-induced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factor-beta1. Am J Pathol (2007) 1.10
Blockade of KCa3.1 ameliorates renal fibrosis through the TGF-β1/Smad pathway in diabetic mice. Diabetes (2013) 1.10
Role of Kruppel-like factor 6 in transforming growth factor-beta1-induced epithelial-mesenchymal transition of proximal tubule cells. Am J Physiol Renal Physiol (2008) 1.07
Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells. J Biol Chem (2004) 1.06
CTGF and chronic kidney fibrosis. Front Biosci (Schol Ed) (2009) 1.04
Nedd4 and Nedd4-2: ubiquitin ligases at work in the neuron. Int J Biochem Cell Biol (2012) 1.03
Albumin transport and processing by the proximal tubule: physiology and pathophysiology. Curr Opin Nephrol Hypertens (2007) 1.03
Transforming growth factor-beta1 differentially mediates fibronectin and inflammatory cytokine expression in kidney tubular cells. Am J Physiol Renal Physiol (2006) 1.02
In vivo visualization of albumin degradation in the proximal tubule. Kidney Int (2008) 1.01
TGF-beta1 induces IL-8 and MCP-1 through a connective tissue growth factor-independent pathway. Am J Physiol Renal Physiol (2005) 1.01
PKC-alpha-mediated remodeling of the actin cytoskeleton is involved in constitutive albumin uptake by proximal tubule cells. Am J Physiol Renal Physiol (2005) 1.01
Adipokines as a link between obesity and chronic kidney disease. Am J Physiol Renal Physiol (2013) 1.01
ClC-5: a chloride channel with multiple roles in renal tubular albumin uptake. Int J Biochem Cell Biol (2005) 0.99
Cofilin interacts with ClC-5 and regulates albumin uptake in proximal tubule cell lines. J Biol Chem (2003) 0.97
Allelic depletion of grem1 attenuates diabetic kidney disease. Diabetes (2009) 0.97
Transcription factors Krüppel-like factor 6 and peroxisome proliferator-activated receptor-{gamma} mediate high glucose-induced thioredoxin-interacting protein. Am J Pathol (2009) 0.96
The role of Sgk-1 in the upregulation of transport proteins by PPAR-{gamma} agonists in human proximal tubule cells. Nephrol Dial Transplant (2008) 0.96
Renal protection in diabetes: lessons from ONTARGET. Cardiovasc Diabetol (2010) 0.95
High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule. Kidney Int (2005) 0.95
Molecular changes in proximal tubule function in diabetes mellitus. Clin Exp Pharmacol Physiol (2004) 0.95
In vivo study of spherical gold nanoparticles: inflammatory effects and distribution in mice. PLoS One (2013) 0.93
Drug insight: thiazolidinediones and diabetic nephropathy--relevance to renoprotection. Nat Clin Pract Nephrol (2005) 0.93
Isolation, propagation and characterization of primary tubule cell culture from human kidney. Nephrology (Carlton) (2007) 0.92
A yellow fluorescent protein-based assay for high-throughput screening of glycine and GABAA receptor chloride channels. Neurosci Lett (2005) 0.91
Na+-H+ exchanger regulatory factor 1 is a PDZ scaffold for the astroglial glutamate transporter GLAST. Glia (2007) 0.91
PKC alpha is activated but not required during glucose-induced insulin secretion from rat pancreatic islets. Diabetes (2004) 0.91
KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis. Nephrol Dial Transplant (2013) 0.90
Muscarinic-induced recruitment of plasma membrane Ca2+-ATPase involves PSD-95/Dlg/Zo-1-mediated interactions. J Biol Chem (2008) 0.89
Thrombin stimulates proinflammatory and proliferative responses in primary cultures of human proximal tubule cells. Kidney Int (2005) 0.89
Using explicit teaching to improve how bioscience students write to the lay public. Adv Physiol Educ (2007) 0.89
Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation. Biochem Biophys Res Commun (2007) 0.89
Cigarette smoking and brain regulation of energy homeostasis. Front Pharmacol (2012) 0.89
Review article: importance of the kidney proximal tubular cells in thiazolidinedione-mediated sodium and water uptake. Nephrology (Carlton) (2009) 0.89
Differential regulation of Snail by hypoxia and hyperglycemia in human proximal tubule cells. Int J Biochem Cell Biol (2010) 0.88
Regulation of voltage-gated ion channels in excitable cells by the ubiquitin ligases Nedd4 and Nedd4-2. Channels (Austin) (2011) 0.88
High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism. Nephrol Dial Transplant (2007) 0.87
Regulation of albumin endocytosis by PSD95/Dlg/ZO-1 (PDZ) scaffolds. Interaction of Na+-H+ exchange regulatory factor-2 with ClC-5. J Biol Chem (2006) 0.87
Recapitulation of embryological programmes in renal fibrosis--the importance of epithelial cell plasticity and developmental genes. Nephron Physiol (2006) 0.87
Role of oxidative stress in age-associated chronic kidney pathologies. Adv Chronic Kidney Dis (2005) 0.87
Effect of early initiation of dialysis on cardiac structure and function: results from the echo substudy of the IDEAL trial. Am J Kidney Dis (2012) 0.87
Plumbagin ameliorates diabetic nephropathy via interruption of pathways that include NOX4 signalling. PLoS One (2013) 0.87
Renal epidermal growth factor receptor: its role in sodium and water homeostasis in diabetic nephropathy. Clin Exp Pharmacol Physiol (2011) 0.86
Pioglitazone increases renal tubular cell albumin uptake but limits proinflammatory and fibrotic responses. Kidney Int (2004) 0.86
MiRNA-200b represses transforming growth factor-β1-induced EMT and fibronectin expression in kidney proximal tubular cells. Am J Physiol Renal Physiol (2013) 0.86
Proinflammatory and proliferative responses of human proximal tubule cells to PAR-2 activation. Am J Physiol Renal Physiol (2007) 0.86
The interdependence of EGF-R and SGK-1 in fibronectin expression in primary kidney cortical fibroblast cells. Int J Biochem Cell Biol (2007) 0.86
Isolation and primary culture of human proximal tubule cells. Methods Mol Biol (2009) 0.85
Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. Am J Physiol Cell Physiol (2008) 0.84
The roles of Kruppel-like factor 6 and peroxisome proliferator-activated receptor-γ in the regulation of macrophage inflammatory protein-3α at early onset of diabetes. Int J Biochem Cell Biol (2010) 0.84
The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1. Nephrology (Carlton) (2007) 0.84
The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells. Nephrol Dial Transplant (2008) 0.84
The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels. J Biol Chem (2008) 0.83
Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy. Nephron Physiol (2003) 0.83
A method for the isolation of glomerular and tubulointerstitial endothelial cells and a comparison of characteristics with the human umbilical vein endothelial cell model. Nephrology (Carlton) (2004) 0.83
Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-beta1. Am J Physiol Renal Physiol (2011) 0.83
Validity of subjective global assessment as a nutritional marker in end-stage renal disease. Am J Kidney Dis (2002) 0.82
Na+-H+ exchanger regulatory factor 1 (NHERF1) PDZ scaffold binds an internal binding site in the scavenger receptor megalin. Cell Physiol Biochem (2011) 0.81
Rapid loss of glutamine synthetase from astrocytes in response to hypoxia: implications for excitotoxicity. J Chem Neuroanat (2009) 0.81
Insulin secretagogues, but not glucose, stimulate an increase in [Ca2+]i in the fetal human and porcine beta-cell. J Clin Endocrinol Metab (2003) 0.81
G protein coupled receptor transactivation: extending the paradigm to include serine/threonine kinase receptors. Int J Biochem Cell Biol (2012) 0.81
Nutritional state correlates with renal function at the start of dialysis. Perit Dial Int (2003) 0.80
Nedd4-2 (NEDD4L) controls intracellular Na(+)-mediated activity of voltage-gated sodium channels in primary cortical neurons. Biochem J (2014) 0.80
Exendin-4 is effective against metabolic disorders induced by intrauterine and postnatal overnutrition in rodents. Diabetologia (2013) 0.80
Heart failure and nephropathy: catastrophic and interrelated complications of diabetes. Clin J Am Soc Nephrol (2005) 0.80
Biohorizons: An eConference to assess human biology in large, first-year classes. Biochem Mol Biol Educ (2007) 0.80
When should we commence dialysis? The story of a lingering problem and today's scene after the IDEAL study. Nephrol Dial Transplant (2012) 0.80
An evidence based clinical aid for cardiovascular disease--what do GPs think? Aust Fam Physician (2005) 0.79