Early and late life cognitive activity and cognitive systems in old age.

The neuropathology of probable Alzheimer disease and mild cognitive impairment. Ann Neurol (2009) 4.96

Overview and findings from the rush Memory and Aging Project. Curr Alzheimer Res (2012) 4.91

Life-span cognitive activity, neuropathologic burden, and cognitive aging. Neurology (2013) 2.59

The neuropathology of older persons with and without dementia from community versus clinic cohorts. J Alzheimers Dis (2009) 2.54

Kidney function is associated with the rate of cognitive decline in the elderly. Neurology (2009) 2.27

Clinical-pathologic study of depressive symptoms and cognitive decline in old age. Neurology (2014) 2.26

Association between late-life social activity and motor decline in older adults. Arch Intern Med (2009) 2.26

Association of lifetime cognitive engagement and low β-amyloid deposition. Arch Neurol (2012) 2.20

CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol (2011) 2.02

Cerebral amyloid angiopathy pathology and cognitive domains in older persons. Ann Neurol (2010) 1.96

Estimating cerebral microinfarct burden from autopsy samples. Neurology (2013) 1.87

Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons. Sleep (2013) 1.76

Cytomegalovirus infection and risk of Alzheimer disease in older black and white individuals. J Infect Dis (2014) 1.74

Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment. Arch Neurol (2011) 1.68

Memory complaints are related to Alzheimer disease pathology in older persons. Neurology (2006) 1.67

The relationship between cerebral Alzheimer's disease pathology and odour identification in old age. J Neurol Neurosurg Psychiatry (2006) 1.55

Change in frailty and risk of death in older persons. Exp Aging Res (2009) 1.54

Neural reserve, neuronal density in the locus ceruleus, and cognitive decline. Neurology (2013) 1.51

Olfactory impairment in presymptomatic Alzheimer's disease. Ann N Y Acad Sci (2009) 1.49

Frequent cognitive activity compensates for education differences in episodic memory. Am J Geriatr Psychiatry (2010) 1.44

Late-life social activity and cognitive decline in old age. J Int Neuropsychol Soc (2011) 1.38

Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep. JAMA Neurol (2013) 1.37

Life space and risk of Alzheimer disease, mild cognitive impairment, and cognitive decline in old age. Am J Geriatr Psychiatry (2011) 1.35

Loneliness and the rate of motor decline in old age: the Rush Memory and Aging Project, a community-based cohort study. BMC Geriatr (2010) 1.35

Diabetes and cognitive systems in older black and white persons. Alzheimer Dis Assoc Disord (2010) 1.34

Pulmonary function, muscle strength, and incident mobility disability in elders. Proc Am Thorac Soc (2009) 1.31

Social engagement and cognitive function in old age. Exp Aging Res (2009) 1.29

A life course model of cognitive activities, socioeconomic status, education, reading ability, and cognition. J Am Geriatr Soc (2011) 1.27

A genome-wide scan for common variants affecting the rate of age-related cognitive decline. Neurobiol Aging (2011) 1.27

Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age. Arch Gen Psychiatry (2012) 1.26

An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease. Alzheimers Dement (2014) 1.26

Influence of late-life cognitive activity on cognitive health. Neurology (2012) 1.23

Hemoglobin level in older persons and incident Alzheimer disease: prospective cohort analysis. Neurology (2011) 1.22

The impact of health and financial literacy on decision making in community-based older adults. Gerontology (2012) 1.22

A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline. Hum Mol Genet (2012) 1.22

Telephone assessment of cognitive function in the late-onset Alzheimer's disease family study. Arch Neurol (2010) 1.22

Aging, brain disease, and reserve: implications for delirium. Am J Geriatr Psychiatry (2010) 1.20

Increased fragmentation of rest-activity patterns is associated with a characteristic pattern of cognitive impairment in older individuals. Sleep (2012) 1.15

Vulnerability to stress, anxiety, and development of dementia in old age. Am J Geriatr Psychiatry (2011) 1.14

Musculoskeletal pain is associated with incident mobility disability in community-dwelling elders. J Gerontol A Biol Sci Med Sci (2010) 1.14

Childhood adversity and psychosocial adjustment in old age. Am J Geriatr Psychiatry (2006) 1.06

Pulmonary function, muscle strength and mortality in old age. Mech Ageing Dev (2008) 1.06

Relation of hemoglobin to level of cognitive function in older persons. Neuroepidemiology (2008) 1.05

Selected findings from the Religious Orders Study and Rush Memory and Aging Project. J Alzheimers Dis (2013) 1.03

The natural history of cognitive decline in Alzheimer's disease. Psychol Aging (2012) 1.03

Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease. Brain (2014) 1.03

Correlates of health and financial literacy in older adults without dementia. BMC Geriatr (2012) 1.01

Cognition and neuropathology in aging: multidimensional perspectives from the Rush Religious Orders Study and Rush Memory And Aging Project. Curr Alzheimer Res (2011) 1.01

Linking glycemic control and executive function in rural older adults with diabetes mellitus. J Am Geriatr Soc (2010) 1.01

Perceived discrimination and cognition in older African Americans. J Int Neuropsychol Soc (2012) 1.00

Respiratory muscle strength predicts decline in mobility in older persons. Neuroepidemiology (2008) 0.98

Cognitive function is associated with risk aversion in community-based older persons. BMC Geriatr (2011) 0.98

Training Older Adults to Use Tablet Computers: Does It Enhance Cognitive Function? Gerontologist (2014) 0.97

Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease. Biochem Pharmacol (2014) 0.96

Mental work demands, retirement, and longitudinal trajectories of cognitive functioning. J Occup Health Psychol (2014) 0.93

A battery of tests for assessing cognitive function in older Latino persons. Alzheimer Dis Assoc Disord (2009) 0.93

Physical activity for the prevention of cognitive decline: current evidence from observational and controlled studies. Z Gerontol Geriatr (2012) 0.93

The association of mental conditions with blood glucose levels in older adults with diabetes. Aging Ment Health (2012) 0.92

24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex. PLoS Genet (2014) 0.90

Apolipoprotein E and change in episodic memory in blacks and whites. Neuroepidemiology (2013) 0.90

MIND diet associated with reduced incidence of Alzheimer's disease. Alzheimers Dement (2015) 0.89

Correlates of susceptibility to scams in older adults without dementia. J Elder Abuse Negl (2014) 0.89

Explaining differences in episodic memory performance among older African Americans and Whites: the roles of factors related to cognitive reserve and test bias. J Int Neuropsychol Soc (2011) 0.89

Odor identification and progression of parkinsonian signs in older persons. Exp Aging Res (2008) 0.88

Harm avoidance and risk of Alzheimer's disease. Psychosom Med (2011) 0.88

Association between cognitive activity and cognitive function in older Hispanics. J Int Neuropsychol Soc (2012) 0.88

APOE ε4, Alzheimer's disease pathology, cerebrovascular disease, and cognitive change over the years prior to death. Psychol Aging (2013) 0.87

The influence of cognitive decline on well-being in old age. Psychol Aging (2013) 0.87

Vibratory thresholds and mobility in older persons. Muscle Nerve (2009) 0.87

Total daily activity measured with actigraphy and motor function in community-dwelling older persons with and without dementia. Alzheimer Dis Assoc Disord (2012) 0.87

Closed-loop rehabilitation of age-related cognitive disorders. Semin Neurol (2014) 0.86

Effect of common neuropathologies on progression of late life cognitive impairment. Neurobiol Aging (2015) 0.85

MIND diet slows cognitive decline with aging. Alzheimers Dement (2015) 0.85

Neuroticism, extraversion, and motor function in community-dwelling older persons. Am J Geriatr Psychiatry (2013) 0.85

Cognitive decline in older persons initiating anticholinergic medications. PLoS One (2013) 0.85

Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex. J Biol Rhythms (2013) 0.84

Cognitive aging in older Black and White persons. Psychol Aging (2015) 0.83

A neuropsychological study of personality: trait openness in relation to intelligence, fluency, and executive functioning. J Clin Exp Neuropsychol (2010) 0.83

Risk Aversion is Associated with Decision Making among Community-Based Older Persons. Front Psychol (2012) 0.83

The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease. Aging Cell (2011) 0.83

Early life instruction in foreign language and music and incidence of mild cognitive impairment. Neuropsychology (2014) 0.83

Conscientiousness, dementia related pathology, and trajectories of cognitive aging. Psychol Aging (2015) 0.83

TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia. Brain (2016) 0.83

Poor decision making is associated with an increased risk of mortality among community-dwelling older persons without dementia. Neuroepidemiology (2013) 0.81

Neighborhood Influences on Late Life Cognition in the ACTIVE Study. J Aging Res (2012) 0.81

Temporal course and pathologic basis of unawareness of memory loss in dementia. Neurology (2015) 0.81

Harm avoidance and cerebral infarction. Neuropsychology (2013) 0.80

Promoting brain health through exercise and diet in older adults: a physiological perspective. J Physiol (2016) 0.79

Association of financial and health literacy with cognitive health in old age. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn (2016) 0.78

Hippocampal volume and cingulum bundle fractional anisotropy are independently associated with verbal memory in older adults. Brain Imaging Behav (2016) 0.78

Stress and cognitive function in Latino farmworkers. Am J Ind Med (2012) 0.78

Negative social interactions and risk of mild cognitive impairment in old age. Neuropsychology (2014) 0.78

Concurrent and longitudinal relationships between cognitive activity, cognitive performance, and brain volume in older adult women. J Gerontol B Psychol Sci Soc Sci (2014) 0.77

Postural control is associated with cognition and fear of falling in patients with multiple sclerosis. J Neural Transm (Vienna) (2016) 0.77

APOE ε4 and the associations of seafood and long-chain omega-3 fatty acids with cognitive decline. Neurology (2016) 0.76

Cognitive decline is associated with risk aversion and temporal discounting in older adults without dementia. PLoS One (2015) 0.76

Temporal course of neurodegenerative effects on cognition in old age. Neuropsychology (2016) 0.76

Subsets of a large cognitive battery better power clinical trials on early stage Alzheimer's disease. Neuroepidemiology (2014) 0.75

Harm avoidance is associated with progression of parkinsonism in community-dwelling older adults: a prospective cohort study. BMC Geriatr (2014) 0.75

B.A.I.L.A. - a Latin dance randomized controlled trial for older Spanish-speaking Latinos: rationale, design, and methods. Contemp Clin Trials (2014) 0.75

Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.02

Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol (2003) 14.87

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07

Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology (2007) 9.27

Individual differences in rates of change in cognitive abilities of older persons. Psychol Aging (2002) 6.18

Participation in cognitively stimulating activities and risk of incident Alzheimer disease. JAMA (2002) 6.18

Charting a dynamic DNA methylation landscape of the human genome. Nature (2013) 5.80

The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort. Neuroepidemiology (2005) 5.64

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol (2004) 5.11

The neuropathology of probable Alzheimer disease and mild cognitive impairment. Ann Neurol (2009) 4.96

Overview and findings from the rush Memory and Aging Project. Curr Alzheimer Res (2012) 4.91

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71

Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials. Arch Neurol (2004) 4.66

Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell (2013) 4.45

Incidence of Alzheimer disease in a biracial urban community: relation to apolipoprotein E allele status. Arch Neurol (2003) 4.37

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann Neurol (2002) 3.84

Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell (2013) 3.83

Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J Clin Invest (2012) 3.65

Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol (2003) 3.56

Loneliness and risk of Alzheimer disease. Arch Gen Psychiatry (2007) 3.44

Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. Arch Neurol (2004) 3.39

Design of the Chicago Health and Aging Project (CHAP). J Alzheimers Dis (2003) 3.36

Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA (2002) 3.19

Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron (2008) 2.99

Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91

White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study. Neurobiol Aging (2005) 2.79

Much of late life cognitive decline is not due to common neurodegenerative pathologies. Ann Neurol (2013) 2.78

Contribution of Alzheimer disease to mortality in the United States. Neurology (2014) 2.67

Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science (2011) 2.66

Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons. Ann Neurol (2007) 2.66

Microinfarct pathology, dementia, and cognitive systems. Stroke (2011) 2.61

Life-span cognitive activity, neuropathologic burden, and cognitive aging. Neurology (2013) 2.59

Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58

The neuropathology of older persons with and without dementia from community versus clinic cohorts. J Alzheimers Dis (2009) 2.54

Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann Neurol (2012) 2.52

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology. Nat Neurosci (2013) 2.51

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet (2010) 2.51

Olfactory identification and incidence of mild cognitive impairment in older age. Arch Gen Psychiatry (2007) 2.41

Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons. Arch Neurol (2005) 2.38

Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation. Nat Genet (2007) 2.35

Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly. Psychosom Med (2007) 2.27

Association between late-life social activity and motor decline in older adults. Arch Intern Med (2009) 2.26

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology. Neurology (2012) 2.19

Substantia nigra tangles are related to gait impairment in older persons. Ann Neurol (2006) 2.17

A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. Ann Neurol (2015) 2.16

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron (2013) 2.13

Sex differences in the clinical manifestations of Alzheimer disease pathology. Arch Gen Psychiatry (2005) 2.08

Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology (2012) 2.08

Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons. Arch Gen Psychiatry (2010) 2.07

Chronic psychological distress and risk of Alzheimer's disease in old age. Neuroepidemiology (2006) 2.07

Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment. Arch Gen Psychiatry (2007) 2.02

Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. PLoS Genet (2011) 2.02

CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol (2011) 2.02

Change in depressive symptoms during the prodromal phase of Alzheimer disease. Arch Gen Psychiatry (2008) 1.98

Vitamin E and cognitive decline in older persons. Arch Neurol (2002) 1.98

Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease. Arch Neurol (2006) 1.98

Cerebral amyloid angiopathy pathology and cognitive domains in older persons. Ann Neurol (2010) 1.96

Neuroticism, extraversion, and mortality in a defined population of older persons. Psychosom Med (2005) 1.96

Racial disparities in disability: recent evidence from self-reported and performance-based disability measures in a population-based study of older adults. J Gerontol B Psychol Sci Soc Sci (2005) 1.94

The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period. Arch Neurol (2002) 1.92

Racial differences in perceived discrimination in a community population of older blacks and whites. J Aging Health (2004) 1.91

Terminal cognitive decline: accelerated loss of cognition in the last years of life. Psychosom Med (2007) 1.85

Personality and mortality in old age. J Gerontol B Psychol Sci Soc Sci (2004) 1.84

Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease. Ann Neurol (2002) 1.82

Purpose in life is associated with mortality among community-dwelling older persons. Psychosom Med (2009) 1.81

Virological and immunological characteristics of human cytomegalovirus infection associated with Alzheimer disease. J Infect Dis (2013) 1.80

ADCS Prevention Instrument Project: assessment of instrumental activities of daily living for community-dwelling elderly individuals in dementia prevention clinical trials. Alzheimer Dis Assoc Disord (2006) 1.80

Perceived discrimination and mortality in a population-based study of older adults. Am J Public Health (2008) 1.79

Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet (2012) 1.79

A common polymorphism near PER1 and the timing of human behavioral rhythms. Ann Neurol (2012) 1.79

Physical frailty is associated with incident mild cognitive impairment in community-based older persons. J Am Geriatr Soc (2010) 1.78