Published in Genes Cells on November 01, 2005
Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways. J Invest Dermatol (2007) 1.38
Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A (2013) 1.29
Common threads in cardiac fibrosis, infarct scar formation, and wound healing. Fibrogenesis Tissue Repair (2012) 1.12
Periostin modulates myofibroblast differentiation during full-thickness cutaneous wound repair. J Cell Sci (2012) 1.09
Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans. Hepatology (2012) 1.09
Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro. J Cell Sci (2013) 1.03
Cellular and Molecular Characteristics of Scarless versus Fibrotic Wound Healing. Dermatol Res Pract (2010) 0.97
SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy. J Biol Chem (2011) 0.86
Identification and characterization of cartilage oligomeric matrix protein as a novel pathogenic factor in keloids. Am J Pathol (2011) 0.84
Identification of novel keloid biomarkers through profiling of tissue biopsies versus cell cultures in keloid margin specimens compared to adjacent normal skin. Eplasty (2010) 0.83
GENE PROFILING: IMPLICATIONS IN DERMATOLOGY. Expert Rev Dermatol (2016) 0.77
Site-specific gene expression profiling as a novel strategy for unravelling keloid disease pathobiology. PLoS One (2017) 0.75
The Shear Wave Velocity on Elastography Correlates with the Clinical Symptoms and Histopathological Features of Keloids. Plast Reconstr Surg Glob Open (2015) 0.75
Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans. Exp Dermatol (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev (2004) 9.24
A time-dependent phase shift in the mammalian unfolded protein response. Dev Cell (2003) 4.99
Guidelines for the nomenclature of the human heat shock proteins. Cell Stress Chaperones (2008) 4.30
Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol Cell Biol (2005) 3.97
EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin. Science (2003) 3.28
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Science (2008) 3.18
Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med (2012) 2.80
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J Cell Biol (2006) 2.76
Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state. Nat Cell Biol (2006) 2.37
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. Cell Stem Cell (2013) 2.32
Conservation of spermatogonial stem cell self-renewal signaling between mouse and rat. Proc Natl Acad Sci U S A (2005) 2.28
Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508. Mol Biol Cell (2008) 2.14
Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development. PLoS One (2011) 2.01
The rare sugar D-allose has a reducing effect against ischemia-reperfusion injury on the rat abdominal skin island flap model. J Surg Res (2013) 1.97
EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming. J Biol Chem (2006) 1.91
Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I. J Biol Chem (2003) 1.86
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP. J Biol Chem (2008) 1.77
Type I collagen in Hsp47-null cells is aggregated in endoplasmic reticulum and deficient in N-propeptide processing and fibrillogenesis. Mol Biol Cell (2006) 1.77
Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex. J Biol Chem (2009) 1.74
Helicobacter pylori infection increases the risk of colorectal adenoma and adenocarcinoma, especially in women. J Gastroenterol (2005) 1.71
The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens. J Biol Chem (2008) 1.57
Autophagic elimination of misfolded procollagen aggregates in the endoplasmic reticulum as a means of cell protection. Mol Biol Cell (2009) 1.55
Lack of sphingosine 1-phosphate-degrading enzymes in erythrocytes. Biochem Biophys Res Commun (2007) 1.49
Mechanism and components of endoplasmic reticulum-associated degradation. J Biochem (2009) 1.48
Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycans. J Biol Chem (2009) 1.47
Treating a collagen scaffold with a low concentration of nicotine promoted angiogenesis and wound healing. J Surg Res (2012) 1.44
ORF3 protein of hepatitis E virus is essential for virion release from infected cells. J Gen Virol (2009) 1.41
Phenotypic and functional characteristics of spermatogonial stem cells in rats. Dev Biol (2004) 1.41
Surgery without skin resection for eyelid entropion. Ann Plast Surg (2004) 1.38
ARMET is a soluble ER protein induced by the unfolded protein response via ERSE-II element. Cell Struct Funct (2007) 1.37
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries. Biochem Biophys Res Commun (2002) 1.34
Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5. Mol Cell (2011) 1.33
Protein folding and quality control in the ER. Cold Spring Harb Perspect Biol (2011) 1.33
The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells. Genes Cells (2004) 1.32
Hepatitis E Virus (HEV) strains in serum samples can replicate efficiently in cultured cells despite the coexistence of HEV antibodies: characterization of HEV virions in blood circulation. J Clin Microbiol (2010) 1.28
EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsin. Genes Cells (2006) 1.25
Adipose tissue-specific regulation of angiotensinogen in obese humans and mice: impact of nutritional status and adipocyte hypertrophy. Am J Hypertens (2010) 1.22
Characterization of multiple members of the HSP70 family in platyfish culture cells: molecular evolution of stress protein HSP70 in vertebrates. Gene (2004) 1.21
Cytosolic chaperonin protects folding intermediates of Gbeta from aggregation by recognizing hydrophobic beta-strands. Proc Natl Acad Sci U S A (2006) 1.20
Peroxides and peroxidases in the endoplasmic reticulum: integrating redox homeostasis and oxidative folding. Antioxid Redox Signal (2012) 1.18
Specific recognition of the collagen triple helix by chaperone HSP47. II. The HSP47-binding structural motif in collagens and related proteins. J Biol Chem (2006) 1.18
Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidases. Biochem Biophys Res Commun (2007) 1.16
Electron spin resonance detection of hydrogen peroxide as an endothelium-derived hyperpolarizing factor in porcine coronary microvessels. Arterioscler Thromb Vasc Biol (2003) 1.16
SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates. J Biol Chem (2011) 1.16
Membrane topology and essential amino acid residues of Phs1, a 3-hydroxyacyl-CoA dehydratase involved in very long-chain fatty acid elongation. J Biol Chem (2008) 1.10
Sphingosine-1-phosphate lyase is involved in the differentiation of F9 embryonal carcinoma cells to primitive endoderm. J Biol Chem (2003) 1.10
Monoclonal antibodies raised against the ORF3 protein of hepatitis E virus (HEV) can capture HEV particles in culture supernatant and serum but not those in feces. Arch Virol (2008) 1.10
EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans. Glycobiology (2010) 1.10
Functional in vitro analysis of the ERO1 protein and protein-disulfide isomerase pathway. J Biol Chem (2011) 1.10
Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization. J Clin Invest (2003) 1.08
Pirfenidone inhibits the expression of HSP47 in TGF-beta1-stimulated human lung fibroblasts. Life Sci (2007) 1.07
Letter regarding "proximal interphalangeal joint injection through a volar approach: anatomic feasibility and cadaveric assessment of success". J Hand Surg Am (2013) 1.07
Ero1-α and PDIs constitute a hierarchical electron transfer network of endoplasmic reticulum oxidoreductases. J Cell Biol (2013) 1.07
Novel heparin/alginate gel combined with basic fibroblast growth factor promotes nerve regeneration in rat sciatic nerve. J Biomed Mater Res A (2004) 1.07
Identification of cartilage progenitor cells in the adult ear perichondrium: utilization for cartilage reconstruction. Lab Invest (2006) 1.04
NSF/SNAPs and p97/p47/VCIP135 are sequentially required for cell cycle-dependent reformation of the ER network. Genes Cells (2005) 1.04
Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5. Proc Natl Acad Sci U S A (2013) 1.04
Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation. EMBO Rep (2007) 1.04
Xaa-Arg-Gly triplets in the collagen triple helix are dominant binding sites for the molecular chaperone HSP47. J Biol Chem (2001) 1.04
ER Stress Proteins in Autoimmune and Inflammatory Diseases. Front Immunol (2012) 1.04
Accumulation of type IV collagen in dilated ER leads to apoptosis in Hsp47-knockout mouse embryos via induction of CHOP. J Cell Sci (2004) 1.03
Hsp47 as a collagen-specific molecular chaperone. Methods Enzymol (2011) 1.02
Non-anastomotic rupture in the guideline of a Dacron thoracic aortic graft. J Vasc Surg (2005) 1.01
Glycosylation-independent ERAD pathway serves as a backup system under ER stress. Mol Biol Cell (2013) 1.01
Products by the sphingosine kinase/sphingosine 1-phosphate (S1P) lyase pathway but not S1P stimulate mitogenesis. Genes Cells (2005) 1.00
A PSAP motif in the ORF3 protein of hepatitis E virus is necessary for virion release from infected cells. J Gen Virol (2010) 0.99
Prolonged fecal shedding of hepatitis E virus (HEV) during sporadic acute hepatitis E: evaluation of infectivity of HEV in fecal specimens in a cell culture system. J Clin Microbiol (2007) 0.99
Construction of an infectious cDNA clone of hepatitis E virus strain JE03-1760F that can propagate efficiently in cultured cells. J Gen Virol (2009) 0.98
Specific recognition of the collagen triple helix by chaperone HSP47: minimal structural requirement and spatial molecular orientation. J Biol Chem (2005) 0.98
Prevalence of HSP47 antigen and autoantibodies to HSP47 in the sera of patients with mixed connective tissue disease. Biochem Biophys Res Commun (2003) 0.97
Dual-site recognition of different extracellular matrix components by anti-angiogenic/neurotrophic serpin, PEDF. Biochemistry (2003) 0.97
Alpha-defensin enhances expression of HSP47 and collagen-1 in human lung fibroblasts. Life Sci (2007) 0.97
Autophagy eliminates a specific species of misfolded procollagen and plays a protective role in cell survival against ER stress. Autophagy (2009) 0.97
ZNF143 activates gene expression in response to DNA damage and binds to cisplatin-modified DNA. Int J Cancer (2004) 0.96
Insufficient folding of type IV collagen and formation of abnormal basement membrane-like structure in embryoid bodies derived from Hsp47-null embryonic stem cells. Mol Biol Cell (2004) 0.96
Preparation of collagen/gelatin sponge scaffold for sustained release of bFGF. Tissue Eng Part A (2008) 0.96
Novel thioredoxin-related transmembrane protein TMX4 has reductase activity. J Biol Chem (2010) 0.95
Regional heterogeneity in the developing palate: morphological and molecular evidence for normal and abnormal palatogenesis. Congenit Anom (Kyoto) (2006) 0.95
Pirfenidone inhibits TGF-β1-induced over-expression of collagen type I and heat shock protein 47 in A549 cells. BMC Pulm Med (2012) 0.95
Collagen-gelatin scaffold impregnated with bFGF accelerates palatal wound healing of palatal mucosa in dogs. J Surg Res (2011) 0.95
In vivo and in vitro aging is detrimental to mouse spermatogonial stem cell function. Biol Reprod (2010) 0.94
Enhanced wound healing by topical administration of mesenchymal stem cells transfected with stromal cell-derived factor-1. Biomaterials (2013) 0.93
Up-regulated neuronal nitric oxide synthase compensates coronary flow response to bradykinin in endothelial nitric oxide synthase-deficient mice. J Cardiovasc Pharmacol (2004) 0.93
Proinsulin lacking the A7-B7 disulfide bond, Ins2Akita, tends to aggregate due to the exposed hydrophobic surface. Biol Chem (2005) 0.93
Total synthesis of ent-dihydrocorynantheol by using a proline-catalyzed asymmetric addition reaction. Org Lett (2006) 0.93