Published in J Clin Endocrinol Metab on October 25, 2005
Effects of sex, race, and puberty on cortical bone and the functional muscle bone unit in children, adolescents, and young adults. J Clin Endocrinol Metab (2010) 1.66
Fat mass exerts a greater effect on cortical bone mass in girls than boys. J Clin Endocrinol Metab (2009) 1.57
Investigation of sex differences in hip structure in peripubertal children. J Clin Endocrinol Metab (2010) 0.89
The Role of Overweight and Obesity on Bone Health in Korean Adolescents with a Focus on Lean and Fat Mass. J Korean Med Sci (2017) 0.85
The muscle-bone unit of peripheral and central skeletal sites in children and young adults. Osteoporos Int (2010) 0.81
The relationships among bone health, insulin-like growth factor-1 and sex hormones in adolescent female athletes. J Bone Miner Metab (2009) 0.77
Reduced cortical bone density with normal trabecular bone density in girls with Turner syndrome. Osteoporos Int (2010) 0.76
Effects of hypogonadism on bone metabolism in female adolescents and young adults. Nat Rev Endocrinol (2012) 0.76
Quantitative trait locus on chromosome X affects bone loss after maturation in mice. J Bone Miner Metab (2010) 0.76
Effects of Combination Therapy of Alendronate and Hormonal Therapy on Bone Mineral Density in Postmenopausal Korean Women: Multicenter, Randomized Controlled Clinical Trial. J Korean Med Sci (2017) 0.75
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Interleukin-6-deficient mice develop mature-onset obesity. Nat Med (2002) 4.47
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis. Endocrinology (2004) 3.89
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
The gut microbiota regulates bone mass in mice. J Bone Miner Res (2012) 2.92
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med (2013) 2.73
Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA (2008) 2.52
Older men with low serum estradiol and high serum SHBG have an increased risk of fractures. J Bone Miner Res (2008) 2.44
Estrogen receptor (ER)-beta reduces ERalpha-regulated gene transcription, supporting a "ying yang" relationship between ERalpha and ERbeta in mice. Mol Endocrinol (2003) 2.38
Plasma osteocalcin is inversely related to fat mass and plasma glucose in elderly Swedish men. J Bone Miner Res (2009) 2.20
Population genomics in a disease targeted primary cell model. Genome Res (2009) 2.20
Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice. Endocrinology (2008) 2.09
Androgens and bone. Endocr Rev (2004) 2.06
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation. Hum Mol Genet (2009) 2.03
Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden. J Bone Miner Res (2006) 1.91
Smoking is associated with lower bone mineral density and reduced cortical thickness in young men. J Clin Endocrinol Metab (2006) 1.87
Influence of hormone replacement therapy on disease progression and bone mineral density in rheumatoid arthritis. J Rheumatol (2003) 1.81
Long-term leisure-time physical activity and serum metabolome. Circulation (2012) 1.81
Low serum testosterone and high serum estradiol associate with lower extremity peripheral arterial disease in elderly men. The MrOS Study in Sweden. J Am Coll Cardiol (2007) 1.75
Postmenopausal hormone replacement therapy modifies skeletal muscle composition and function: a study with monozygotic twin pairs. J Appl Physiol (1985) (2009) 1.74
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet (2013) 1.72
Large differences in testosterone excretion in Korean and Swedish men are strongly associated with a UDP-glucuronosyl transferase 2B17 polymorphism. J Clin Endocrinol Metab (2005) 1.68
Survival benefit with radium-223 dichloride in a mouse model of breast cancer bone metastasis. J Natl Cancer Inst (2013) 1.66
SOCS2 negatively regulates growth hormone action in vitro and in vivo. J Clin Invest (2005) 1.66
Muscle strength as a predictor of onset of ADL dependence in people aged 75 years. Aging Clin Exp Res (2002) 1.65
Genetic determinants of trabecular and cortical volumetric bone mineral densities and bone microstructure. PLoS Genet (2013) 1.64
Two different pathways for the maintenance of trabecular bone in adult male mice. J Bone Miner Res (2002) 1.62
Association analysis of the polymorphism T1128C in the signal peptide of neuropeptide Y in a Swedish hypertensive population. J Hypertens (2004) 1.59
Tissue effect on genetic control of transcript isoform variation. PLoS Genet (2009) 1.59
Assessment of gene-by-sex interaction effect on bone mineral density. J Bone Miner Res (2012) 1.58
Relationship of sex hormones to bone geometric properties and mineral density in early pubertal girls. J Clin Endocrinol Metab (2004) 1.57
Mature-onset obesity in interleukin-1 receptor I knockout mice. Diabetes (2006) 1.55
WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet (2012) 1.55
The effects of serum testosterone, estradiol, and sex hormone binding globulin levels on fracture risk in older men. J Clin Endocrinol Metab (2009) 1.52
Free testosterone is a positive, whereas free estradiol is a negative, predictor of cortical bone size in young Swedish men: the GOOD study. J Bone Miner Res (2005) 1.51
Serum osteocalcin is not associated with glucose but is inversely associated with leptin across generations of nondiabetic women. J Clin Endocrinol Metab (2012) 1.49
Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus. PLoS Genet (2012) 1.49
Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health? J Physiol (2013) 1.47
Sex steroids, insulin sensitivity and sympathetic nerve activity in relation to affective symptoms in women with polycystic ovary syndrome. Psychoneuroendocrinology (2011) 1.47
Improving cardiovascular fitness by strength or endurance training in women aged 76-78 years. A population-based, randomized controlled trial. Age Ageing (2002) 1.46
A novel biodegradable delivery system for bone morphogenetic protein-2. Plast Reconstr Surg (2008) 1.46
Leptin is a negative independent predictor of areal BMD and cortical bone size in young adult Swedish men. J Bone Miner Res (2006) 1.46
Impact of electro-acupuncture and physical exercise on hyperandrogenism and oligo/amenorrhea in women with polycystic ovary syndrome: a randomized controlled trial. Am J Physiol Endocrinol Metab (2010) 1.42
Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development. Proc Natl Acad Sci U S A (2007) 1.41
Circulating fibroblast growth factor-23 is associated with fat mass and dyslipidemia in two independent cohorts of elderly individuals. Arterioscler Thromb Vasc Biol (2010) 1.34
Aging, muscle fiber type, and contractile function in sprint-trained athletes. J Appl Physiol (1985) (2006) 1.34
Assessing body composition with DXA and bioimpedance: effects of obesity, physical activity, and age. Obesity (Silver Spring) (2008) 1.32
Association of amount of physical activity with cortical bone size and trabecular volumetric BMD in young adult men: the GOOD study. J Bone Miner Res (2005) 1.32
Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet (2011) 1.30
Secreted tartrate-resistant acid phosphatase 5b is a Marker of osteoclast number in human osteoclast cultures and the rat ovariectomy model. Calcif Tissue Int (2007) 1.30
Estrogens as regulators of bone health in men. Nat Rev Endocrinol (2009) 1.26
Estrogen receptor-α in osteocytes is important for trabecular bone formation in male mice. Proc Natl Acad Sci U S A (2013) 1.26
Sex steroid actions in male bone. Endocr Rev (2014) 1.26
A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet (2012) 1.23
Low serum testosterone and estradiol predict mortality in elderly men. J Clin Endocrinol Metab (2009) 1.23
Risk factors for clinical stress fractures in male military recruits: a prospective cohort study. Bone (2005) 1.22
Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2. J Bone Miner Res (2013) 1.22
The effect of hormone replacement therapy and/or exercise on skeletal muscle attenuation in postmenopausal women: a yearlong intervention. Clin Physiol Funct Imaging (2005) 1.21
Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual and body composition in 10-12-y-old girls: a 2-y randomized trial. Am J Clin Nutr (2005) 1.21
The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men. J Clin Endocrinol Metab (2007) 1.19
Pubertal timing is an independent predictor of central adiposity in young adult males: the Gothenburg osteoporosis and obesity determinants study. Diabetes (2006) 1.19
Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23. Nephrol Dial Transplant (2007) 1.18
Effects of liver-derived insulin-like growth factor I on bone metabolism in mice. J Bone Miner Res (2002) 1.18
Ethanol prevents development of destructive arthritis. Proc Natl Acad Sci U S A (2006) 1.18
Osteoclast-derived serum tartrate-resistant acid phosphatase 5b in Albers-Schonberg disease (type II autosomal dominant osteopetrosis). Clin Chem (2004) 1.17
Biochemical markers of bone metabolism and prediction of fracture in elderly women. J Bone Miner Res (2003) 1.16
Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1. EMBO J (2002) 1.16
Comparable amounts of sex steroids are made outside the gonads in men and women: strong lesson for hormone therapy of prostate and breast cancer. J Steroid Biochem Mol Biol (2008) 1.16
Intracellular machinery for matrix degradation in bone-resorbing osteoclasts. J Bone Miner Res (2004) 1.15
Regulation of adult bone turnover by sex steroids. J Cell Physiol (2010) 1.15
Vitamin D status as a determinant of peak bone mass in young Finnish men. J Clin Endocrinol Metab (2004) 1.14
Increased cortical bone mineralization in imatinib treated patients with chronic myelogenous leukemia. Haematologica (2008) 1.13
Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice. Proc Natl Acad Sci U S A (2003) 1.11
Genome-wide association meta-analysis of cortical bone mineral density unravels allelic heterogeneity at the RANKL locus and potential pleiotropic effects on bone. PLoS Genet (2010) 1.10
Fibroblast growth factor-23 is associated with parathyroid hormone and renal function in a population-based cohort of elderly men. Eur J Endocrinol (2008) 1.10
Serum fibroblast growth factor-23 (FGF-23) and fracture risk in elderly men. J Bone Miner Res (2011) 1.08
Strategies to improve vitamin D status in northern European children: exploring the merits of vitamin D fortification and supplementation. J Nutr (2006) 1.08
Acute heavy-resistance exercise-induced pain and neuromuscular fatigue in elderly women with fibromyalgia and in healthy controls: effects of strength training. Arthritis Rheum (2006) 1.07