Published in Mol Cell Proteomics on October 26, 2005
Spectral domain optical coherence tomography in mouse models of retinal degeneration. Invest Ophthalmol Vis Sci (2009) 2.08
Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc Natl Acad Sci U S A (2006) 1.61
Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry. Mol Cell Proteomics (2010) 1.41
Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse. Cell Death Dis (2010) 1.15
PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function. PLoS One (2010) 1.10
Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. PLoS One (2014) 1.04
Do calcium channel blockers rescue dying photoreceptors in the Pde6b ( rd1 ) mouse? Adv Exp Med Biol (2010) 0.92
Profiling of microRNAs involved in retinal degeneration caused by selective Müller cell ablation. PLoS One (2015) 0.88
Synaptic remodeling generates synchronous oscillations in the degenerated outer mouse retina. Front Neural Circuits (2014) 0.86
The role of mislocalized phototransduction in photoreceptor cell death of retinitis pigmentosa. PLoS One (2012) 0.83
DNA methylation and differential gene regulation in photoreceptor cell death. Cell Death Dis (2014) 0.82
Dopamine and full-field illumination activate D1 and D2-D5-type receptors in adult rat retinal ganglion cells. J Comp Neurol (2012) 0.80
Silencing of tuberin enhances photoreceptor survival and function in a preclinical model of retinitis pigmentosa (an american ophthalmological society thesis). Trans Am Ophthalmol Soc (2014) 0.79
Small Retinoprotective Peptides Reveal a Receptor-binding Region on Pigment Epithelium-derived Factor. J Biol Chem (2015) 0.77
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity. Hum Mol Genet (2005) 3.49
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J Neurosci (2011) 2.52
Integrative analysis of the mitochondrial proteome in yeast. PLoS Biol (2004) 2.31
Mutations in LCA5, encoding the ciliary protein lebercilin, cause Leber congenital amaurosis. Nat Genet (2007) 2.16
Spectral domain optical coherence tomography in mouse models of retinal degeneration. Invest Ophthalmol Vis Sci (2009) 2.08
ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome. Nat Methods (2007) 2.04
Photoreceptor cell death mechanisms in inherited retinal degeneration. Mol Neurobiol (2008) 1.94
A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes. Proteomics (2007) 1.91
The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro. J Neurochem (2009) 1.71
WI-PHI: a weighted yeast interactome enriched for direct physical interactions. Proteomics (2007) 1.55
Deciphering membrane-associated molecular processes in target tissue of autoimmune uveitis by label-free quantitative mass spectrometry. Mol Cell Proteomics (2010) 1.41
Phosphopeptide analysis reveals two discrete clusters of phosphorylation in the N-terminus and the Roc domain of the Parkinson-disease associated protein kinase LRRK2. J Proteome Res (2010) 1.38
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nat Genet (2013) 1.32
Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice. J Clin Invest (2011) 1.31
ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations. Invest Ophthalmol Vis Sci (2009) 1.30
Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse. J Neurosci (2007) 1.30
Approaching clinical proteomics: current state and future fields of application in fluid proteomics. Clin Chem Lab Med (2009) 1.27
Tandem affinity purification of protein complexes from mammalian cells by the Strep/FLAG (SF)-TAP tag. Methods Mol Biol (2009) 1.18
Pitchfork regulates primary cilia disassembly and left-right asymmetry. Dev Cell (2010) 1.18
Proteomic profiling of primary retinal Müller glia cells reveals a shift in expression patterns upon adaptation to in vitro conditions. Glia (2003) 1.17
A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics. Mol Cell Proteomics (2010) 1.15
Complement factor D in age-related macular degeneration. Invest Ophthalmol Vis Sci (2011) 1.14
A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa. Hum Mol Genet (2010) 1.13
Calpain is activated in degenerating photoreceptors in the rd1 mouse. J Neurochem (2006) 1.13
PKG activity causes photoreceptor cell death in two retinitis pigmentosa models. J Neurochem (2009) 1.12
A community standard format for the representation of protein affinity reagents. Mol Cell Proteomics (2009) 1.11
Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila. PLoS Genet (2010) 1.08
MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer. Am J Pathol (2011) 1.08
Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats. PLoS One (2011) 1.08
Direct comparison of MS-based label-free and SILAC quantitative proteome profiling strategies in primary retinal Müller cells. Proteomics (2012) 1.04
Comparative proteome analysis of native differentiated and cultured dedifferentiated human RPE cells. Invest Ophthalmol Vis Sci (2003) 1.04
Strep/FLAG tandem affinity purification (SF-TAP) to study protein interactions. Curr Protoc Protein Sci (2009) 1.04
GDNF family ligands trigger indirect neuroprotective signaling in retinal glial cells. Mol Cell Biol (2006) 1.04
Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast. J Biol Chem (2006) 1.03
Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer. J Pathol (2012) 1.03
Clearance of Rhodopsin(P23H) aggregates requires the ERAD effector VCP. Biochim Biophys Acta (2010) 1.03
Two-dimensional electrophoresis of membrane proteins. Anal Bioanal Chem (2007) 1.02
CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina. Brain Res (2006) 1.02
LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation. J Cell Sci (2012) 1.01
Identification of paracrine neuroprotective candidate proteins by a functional assay-driven proteomics approach. Mol Cell Proteomics (2008) 1.00
Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain. PLoS Genet (2013) 1.00
Delta-like 1 participates in the specification of ventral midbrain progenitor derived dopaminergic neurons. J Neurochem (2007) 0.98
ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2. PLoS One (2010) 0.98
Cohort profile: Greifswald approach to individualized medicine (GANI_MED). J Transl Med (2014) 0.97
Up-regulation and increased phosphorylation of protein kinase C (PKC) delta, mu and theta in the degenerating rd1 mouse retina. Mol Cell Neurosci (2006) 0.97
The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase. Hum Mol Genet (2011) 0.97
Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3. Proc Natl Acad Sci U S A (2013) 0.96
Proteomic analysis of the porcine interphotoreceptor matrix. Proteomics (2005) 0.96
Prothymosin-α interacts with mutant huntingtin and suppresses its cytotoxicity in cell culture. J Biol Chem (2011) 0.95
Structural and functional protein network analyses predict novel signaling functions for rhodopsin. Mol Syst Biol (2011) 0.95
Retinal Mueller glial cells trigger the hallmark inflammatory process in autoimmune uveitis. J Proteome Res (2007) 0.95
Membrane-initiated effects of progesterone on calcium dependent signaling and activation of VEGF gene expression in retinal glial cells. Glia (2007) 0.95
Improved proteome analysis of Saccharomyces cerevisiae mitochondria by free-flow electrophoresis. Proteomics (2003) 0.95
Apoe, Mbl2, and Psp plasma protein levels correlate with diabetic phenotype in NZO mice--an optimized rapid workflow for SRM-based quantification. J Proteome Res (2013) 0.94
Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP). Invest Ophthalmol Vis Sci (2009) 0.94
Identification and functional validation of novel autoantigens in equine uveitis. Mol Cell Proteomics (2006) 0.94
Cellular phenotypes of human model neurons (NT2) after differentiation in aggregate culture. Cell Tissue Res (2009) 0.93
Differential protein profiling of primary versus immortalized human RPE cells identifies expression patterns associated with cytoskeletal remodeling and cell survival. J Proteome Res (2006) 0.93
Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases. Dev Cell (2011) 0.93
A new method to customize protein expression vectors for fast, efficient and background free parallel cloning. BMC Biotechnol (2013) 0.93
ER stress in retinal degeneration: a target for rational therapy? Trends Mol Med (2011) 0.93
Clinical response to chemotherapy in oesophageal adenocarcinoma patients is linked to defects in mitochondria. J Pathol (2013) 0.92
Photoreceptor rescue and toxicity induced by different calpain inhibitors. J Neurochem (2010) 0.92
MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma. J Proteomics (2012) 0.92
The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation. Mol Neurodegener (2014) 0.91
GDNF-induced osteopontin from Müller glial cells promotes photoreceptor survival in the Pde6brd1 mouse model of retinal degeneration. Glia (2011) 0.90
Integration between abutting retinas: role of glial structures and associated molecules at the interface. Invest Ophthalmol Vis Sci (2004) 0.90
Label-free LC-MSMS analysis of vitreous from autoimmune uveitis reveals a significant decrease in secreted Wnt signalling inhibitors DKK3 and SFRP2. J Proteomics (2012) 0.90
S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI imaging. J Mol Med (Berl) (2011) 0.89
Down-regulation of pigment epithelium-derived factor in uveitic lesion associates with focal vascular endothelial growth factor expression and breakdown of the blood-retinal barrier. Proteomics (2007) 0.89
Role of phosphatidylinositol 3-kinase in neuronal survival and axonal outgrowth of adult mouse dorsal root ganglia explants. J Neurosci Res (2003) 0.89
Functional and structural evaluation after AAV.RPE65 gene transfer in the canine model of Leber's congenital amaurosis. Adv Exp Med Biol (2003) 0.89
Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3). Hum Mol Genet (2012) 0.89
Equine recurrent uveitis--a spontaneous horse model of uveitis. Ophthalmic Res (2008) 0.89
Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein. J Biol Chem (2009) 0.87
rd1 mouse retina shows imbalance in cellular distribution and levels of TIMP-1/MMP-9, TIMP-2/MMP-2 and sulfated glycosaminoglycans. Ophthalmic Res (2005) 0.87
CRALBP is a highly prevalent autoantigen for human autoimmune uveitis. Clin Dev Immunol (2007) 0.86
Approaching clinical proteomics: current state and future fields of application in cellular proteomics. Cytometry A (2009) 0.86
Neuronal integration in an abutting-retinas culture system. Invest Ophthalmol Vis Sci (2003) 0.85
Antioxidants rescue photoreceptors in rd1 mice: Relationship with thiol metabolism. Free Radic Biol Med (2009) 0.85
Mitogen-activated protein kinase inhibition reveals differences in signalling pathways activated by neurotrophin-3 and other growth-stimulating conditions of adult mouse dorsal root ganglia neurons. J Neurosci Res (2002) 0.85
Bovine neonatal pancytopenia--comparative proteomic characterization of two BVD vaccines and the producer cell surface proteome (MDBK). BMC Vet Res (2013) 0.85
High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry. Proteomics (2014) 0.85
Insights into the membrane proteome of rat liver peroxisomes: microsomal glutathione-S-transferase is shared by both subcellular compartments. Proteomics (2006) 0.84
Serum PEDF levels are decreased in a spontaneous animal model for human autoimmune uveitis. J Proteome Res (2009) 0.84
Integrative proteomic and microRNA analysis of primary human coronary artery endothelial cells exposed to low-dose gamma radiation. Radiat Environ Biophys (2012) 0.83
Calretinin interacts with huntingtin and reduces mutant huntingtin-caused cytotoxicity. J Neurochem (2012) 0.83
Differential analysis of Saccharomyces cerevisiae mitochondria by free flow electrophoresis. Mol Cell Proteomics (2006) 0.83
In vivo assessment of rodent retinal structure using spectral domain optical coherence tomography. Adv Exp Med Biol (2012) 0.83