Published in Trans R Soc Trop Med Hyg on October 27, 2005
Human malarial disease: a consequence of inflammatory cytokine release. Malar J (2006) 2.36
Over-diagnosis and co-morbidity of severe malaria in African children: a guide for clinicians. Am J Trop Med Hyg (2007) 2.08
The role of previously unmeasured organic acids in the pathogenesis of severe malaria. Crit Care (2015) 1.39
Decorticate, decerebrate and opisthotonic posturing and seizures in Kenyan children with cerebral malaria. Malar J (2005) 0.81
Clinical signs, profound acidemia, hypoglycemia, and hypernatremia are predictive of mortality in 1,400 critically ill neonatal calves with diarrhea. PLoS One (2017) 0.75
Indicators of life-threatening malaria in African children. N Engl J Med (1995) 13.17
Enzymic determination of D(-)-beta-hydroxybutyric acid and acetoacetic acid in blood. Biochem J (1962) 12.21
The ears of the hippopotamus: manifestations, determinants, and estimates of the malaria burden. Am J Trop Med Hyg (2001) 8.21
Modern quantitative acid-base chemistry. Can J Physiol Pharmacol (1983) 5.92
Changing home treatment of childhood fevers by training shop keepers in rural Kenya. Trop Med Int Health (1999) 4.43
Anion gap and hypoalbuminemia. Crit Care Med (1998) 3.67
Severe falciparum malaria in children: current understanding of pathophysiology and supportive treatment. Pharmacol Ther (1998) 3.57
The pH-log pCO2 blood acid-base nomogram revised. Scand J Clin Lab Invest (1962) 2.56
Prognostic indicators of early and late death in children admitted to district hospital in Kenya: cohort study. BMJ (2003) 2.56
The pathophysiologic and prognostic significance of acidosis in severe adult malaria. Crit Care Med (2000) 2.42
Diagnosis of metabolic acid-base disturbances in critically ill patients. Am J Respir Crit Care Med (2000) 2.29
Acid-base status in paediatric Plasmodium falciparum malaria. Q J Med (1993) 2.22
Bicarbonate does not improve hemodynamics in critically ill patients who have lactic acidosis. A prospective, controlled clinical study. Ann Intern Med (1990) 2.20
Acidosis in severe childhood malaria. QJM (1997) 2.12
Lactic acidosis and hypoglycaemia in children with severe malaria: pathophysiological and prognostic significance. Trans R Soc Trop Med Hyg (1994) 1.96
Clinical features and outcome of severe malaria in Gambian children. Clin Infect Dis (1995) 1.96
Unidentified acids of strong prognostic significance in severe malaria. Crit Care Med (2004) 1.95
Determinants of blood pH in health and disease. Crit Care (2000) 1.94
The role of serum proteins in acid-base equilibria. J Lab Clin Med (1991) 1.70
Bicarbonate therapy in severe diabetic ketoacidosis. Ann Intern Med (1986) 1.53
Severe malaria in children in Papua New Guinea. QJM (1996) 1.52
Conventional or physicochemical approach in intensive care unit patients with metabolic acidosis. Crit Care (2003) 1.45
A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group. N Engl J Med (1992) 1.42
Deep breathing in children with severe malaria: indicator of metabolic acidosis and poor outcome. Am J Trop Med Hyg (1996) 1.38
Treatment of malaria fever episodes among children in Malawi: results of a KAP survey. Trop Med Parasitol (1994) 1.28
The fall of the serum anion gap. Arch Intern Med (1990) 1.28
Chronic salicylate poisoning and severe malaria. Lancet (1996) 1.25
Organic acids and the uremic syndrome: protein metabolite hypothesis in the progression of chronic renal failure. Semin Nephrol (1996) 1.23
Clinical assessment of acid-base status. Strong ion difference theory. Vet Clin North Am Food Anim Pract (1999) 1.15
Stewart's quantitative acid-base chemistry: applications in biology and medicine. Respir Physiol (1993) 1.14
The value of the chloride: sodium ratio in differentiating the aetiology of metabolic acidosis. Intensive Care Med (2001) 1.13
Sodium bicarbonate therapy in severe diabetic ketoacidosis. Am J Med (1983) 1.09
Hyponatraemia and dehydration in severe malaria. Arch Dis Child (1996) 1.09
Perturbations in electrolyte levels in kenyan children with severe malaria complicated by acidosis. Clin Infect Dis (2004) 1.07
Population kinetics, efficacy, and safety of dichloroacetate for lactic acidosis due to severe malaria in children. J Clin Pharmacol (2003) 1.05
Metabolic effects of bicarbonate in the treatment of diabetic ketoacidosis. Br Med J (Clin Res Ed) (1984) 0.98
Treating intraoperative hyperchloremic acidosis with sodium bicarbonate or tris-hydroxymethyl aminomethane: a randomized prospective study. Anesth Analg (2003) 0.94
Counterproductive effects of sodium bicarbonate in diabetic ketoacidosis. J Clin Endocrinol Metab (1996) 0.92
Update on value of the anion gap in clinical diagnosis and laboratory evaluation. Clin Chim Acta (2001) 0.90
Treatment of metabolic acidosis. Curr Opin Crit Care (2003) 0.89
Evaluation of fluorescence polarization immunoassay for quantitation of serum salicylates. Ther Drug Monit (1985) 0.77
Role of tissue hypoxia and defective renal acid excretion in the development of acidosis in infantile diarrhea. Pediatrics (1971) 0.77
Reference ranges of electrolyte and anion gap in venous whole blood and plasma of healthy school children. Clin Chim Acta (2003) 0.76
Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa. Lancet (1997) 13.64
Averting a malaria disaster. Lancet (1999) 9.40
IL-4 directs the development of Th2-like helper effectors. J Immunol (1990) 7.20
Microscopy and outpatient malaria case management among older children and adults in Kenya. Trop Med Int Health (2006) 6.26
Predictors of the quality of health worker treatment practices for uncomplicated malaria at government health facilities in Kenya. Int J Epidemiol (2004) 3.51
Incidence of clinically significant bacteraemia in children who present to hospital in Kenya: community-based observational study. Lancet (2006) 3.02
Bacteraemia complicating severe malaria in children. Trans R Soc Trop Med Hyg (1999) 2.76
Aetiology, outcome, and risk factors for mortality among adults with acute pneumonia in Kenya. Lancet (2000) 2.74
Symptomatic relapse after oral vancomycin therapy of antibiotic-associated pseudomembranous colitis. Gastroenterology (1980) 2.60
Sequence analysis and expression patterns divide the maize knotted1-like homeobox genes into two classes. Plant Cell (1994) 2.33
Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria. Proc Natl Acad Sci U S A (2001) 2.27
Severe P. falciparum malaria in Kenyan children: evidence for hypovolaemia. QJM (2003) 2.18
Policy interventions that attract nurses to rural areas: a multicountry discrete choice experiment. Bull World Health Organ (2010) 2.17
Acidosis in severe childhood malaria. QJM (1997) 2.12
CD4+ T cell subsets. Lymphokine secretion of memory cells and of effector cells that develop from precursors in vitro. J Immunol (1990) 2.08
Distinct regulation of lymphokine production is found in fresh versus in vitro primed murine helper T cells. J Immunol (1990) 1.73
Paediatric survival and re-admission risks following hospitalization on the Kenyan coast. Trop Med Int Health (2000) 1.73
Risk and aetiology of diarrhoea at various tourist destinations. Lancet (2000) 1.72
Intracranial hypertension in Africans with cerebral malaria. Arch Dis Child (1997) 1.71
Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens. J Immunol (1984) 1.62
Physiologic consequences of positive end-expiratory pressure (PEEP) ventilation. Ann Surg (1973) 1.58
Ifosfamide nephrotoxicity: limited influence of metabolism and mode of administration during repeated therapy in paediatrics. Eur J Cancer (1996) 1.54
The disposition of intramuscular artemether in children with cerebral malaria; a preliminary study. Trans R Soc Trop Med Hyg (1997) 1.46
The role of IL4 and IL5: characterization of a distinct helper T cell subset that makes IL4 and IL5 (Th2) and requires priming before induction of lymphokine secretion. Immunol Rev (1988) 1.44
The pathogenesis of severe malaria in African children. Ann Trop Med Parasitol (1996) 1.39
Treatment of male infertility: the ICSI revolution is secure. N Z Med J (1996) 1.38
Naturally acquired antibodies to polymorphic and conserved epitopes of Plasmodium falciparum merozoite surface protein 3. Parasite Immunol (2007) 1.37
Erythromycin ointment for ocular prophylaxis of neonatal chlamydial infection. JAMA (1980) 1.36
Ophthalmia neonatorum associated with maternal chlamydial infections. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol (1977) 1.34
Amplification of genomic sequences flanking transposable elements in host and heterologous plants: a tool for transposon tagging and genome characterization. Nucleic Acids Res (1990) 1.31
Peripheral blood dendritic cells in children with acute Plasmodium falciparum malaria. Blood (2001) 1.29
Estimation of the sequestered parasite load in severe malaria patients using both host and parasite markers. Parasitology (2005) 1.28
Chronic salicylate poisoning and severe malaria. Lancet (1996) 1.25
Oxygen is an essential medicine: a call for international action. Int J Tuberc Lung Dis (2010) 1.23
Limited-host-range plasmid of Agrobacterium tumefaciens: molecular and genetic analyses of transferred DNA. J Bacteriol (1985) 1.20
Parasite viability during treatment of severe falciparum malaria: differential effects of artemether and quinine. Am J Trop Med Hyg (1995) 1.19
An empirical test of telephone screening to identify potential dementia cases. Int Psychogeriatr (1995) 1.18
Chlorproguanil-dapsone: effective treatment for uncomplicated falciparum malaria. Antimicrob Agents Chemother (1997) 1.15
Effect of intravenous infusion of insulin in diabetics with acute myocardial infarction. Br Med J (Clin Res Ed) (1985) 1.15
Comparative efficacy of 10 antimicrobial agents in experimental infections with Bacteroides fragilis. J Infect Dis (1982) 1.13
An open randomized trial of artemether versus quinine in the treatment of cerebral malaria in African children. Trans R Soc Trop Med Hyg (1996) 1.13
Cephalosporin-associated pseudomembranous colitis due to Clostridium difficile. JAMA (1979) 1.13
Correlation of pulmonary wedge and left atrial pressures. A study in the patient receiving positive end expiratory pressure ventilation. Arch Surg (1974) 1.11
Abnormal respiratory patterns in childhood cerebral malaria. Trans R Soc Trop Med Hyg (1998) 1.10
Clinical algorithm for malaria in Africa. Lancet (1996) 1.10
The role of sequential administration of sulphadoxine/pyrimethamine following quinine in the treatment of severe falciparum malaria in children. Trop Med Int Health (2005) 1.07
Serotype distribution and prevalence of resistance to benzylpenicillin in three representative populations of Streptococcus pneumoniae isolates from the coast of Kenya. Clin Infect Dis (1998) 1.07
Ly phenotypes and MHC recognition: the allohelper that recognizes K or D is a mature Ly123 cell. J Immunol (1979) 1.06
In vitro antimicrobial susceptibility testing of bacterial enteropathogens causing traveler's diarrhea in four geographic regions. Antimicrob Agents Chemother (2001) 1.03
Tuberculosis among homeless people in London: an effective model of screening and treatment. Int J Tuberc Lung Dis (1999) 1.03
Inflammatory mediators in children with protein-energy malnutrition. Am J Clin Nutr (1997) 1.00
Geophagy, iron status and anaemia among pregnant women on the coast of Kenya. Trans R Soc Trop Med Hyg (1999) 1.00
A randomised, controlled trial of once daily and multi-dose daily gentamicin in young Kenyan infants. Arch Dis Child (2004) 0.98
Analysis of pig's coronary arterial blood flow with detailed anatomical data. Ann Biomed Eng (1997) 0.96
Non-typhi salmonella in children with severe malaria. East Afr Med J (2002) 0.96
An outbreak of intravenous cannulae associated nosocomial septicaemia due to multidrug-resistant Klebsiella pneumoniae. East Afr Med J (1994) 0.93
Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria. Br J Clin Pharmacol (1995) 0.93
Short report: codon 125 polymorphism of CD31 and susceptibility to malaria. Am J Trop Med Hyg (2001) 0.92
Management of hepatic epithelioid haemangio-endothelioma in children: what option? Br J Cancer (2004) 0.92
Outcome of children with posterior fossa medulloblastoma: a single institution experience over the decade 1994-2003. Childs Nerv Syst (2006) 0.91
Cardiopulmonary adjustments following single high dosage administration of methylprednisolone in traumatized man. Ann Surg (1975) 0.91
Computed tomography in leptomeningeal infections. AJR Am J Roentgenol (1978) 0.91
Genotypes of multidrug-resistant Salmonella enterica serotype typhimurium from two regions of Kenya. FEMS Immunol Med Microbiol (2000) 0.91
Tetracycline toxicity in haemoglobinuria. Br Med J (1966) 0.90
Synapse-forming axons and recombinant agrin induce microprocess formation on myotubes. J Neurosci (2001) 0.89
Chemical composition of baboon plant foods: implications for the interpretation of intra- and interspecific differences in diet. Folia Primatol (Basel) (1993) 0.88
Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: unbound quinine concentrations following a simple loading dose regimen. Trans R Soc Trop Med Hyg (1995) 0.87
Role of antigen in the B cell response. Specific antigen and the lymphokine IL-5 synergize to drive B cell lymphoma proliferation and differentiation to Ig secretion. J Immunol (1988) 0.86
Fear of failure: a place for the trial of instrumental delivery. Br J Obstet Gynaecol (1987) 0.84
The effect of hypotensive anesthesia on blood loss and operative time during Le Fort I osteotomies. J Oral Maxillofac Surg (2000) 0.84
Fertilization of human oocytes in vitro by spermatozoa from oligozoospermic and normospermic men. Int J Androl (1989) 0.84
Lipid in the human gallbladder mucosa. A histochemical study by light and electron microscopy. J Pathol (1985) 0.83
Medication use in residential care facilities for the elderly. Ann Pharmacother (1999) 0.83
Bayesian age-stage modelling of Plasmodium falciparum sequestered parasite loads in severe malaria patients. Parasitology (2004) 0.82
Infantile clivus chordoma without clivus involvement: case report and review of the literature. Childs Nerv Syst (2006) 0.81
Two N-terminal self-association domains are required for the dominant negative transcriptional activity of WT1 Denys-Drash mutant proteins. Biochem Biophys Res Commun (1997) 0.81
Structural changes in simian virus 40 chromatin as probed by restriction endonucleases. J Virol (1979) 0.81
Large maxillary mass in a child. J Oral Maxillofac Surg (2001) 0.81
Endogenous excitotoxic agents. Ciba Found Symp (1987) 0.81
Effects of sodium monensin on reproductive performance of dairy cattle. I. Effects on conception rates, calving-to-conception intervals, calving-to-heat and milk production in dairy cows. Aust Vet J (1994) 0.80
Virtual reality simulators for dermatologic surgery: measuring their validity as a teaching tool. Dermatol Surg (2001) 0.80
Estimation of renal function and its potential impact on carboplatin dosing in children with cancer. Br J Cancer (2008) 0.78
The management of severe malaria in children: a review. East Afr Med J (1995) 0.78
Touch-plate and statolith formation in graviceptors of ephyrae which developed while weightless in space. Scanning Microsc (1996) 0.78
Virtual reality for dermatologic surgery: virtually a reality in the 21st century. J Am Acad Dermatol (2000) 0.78
Preclinical drug evaluation system in the Plasmodium knowlesi baboon model of malaria: the methotrexate study. J Med Primatol (2013) 0.77
Longitudinal studies on chlamydial infections in the first year of life. Pediatr Infect Dis (1983) 0.77
Postoperative visual loss after plastic surgery: case report and a novel continuous real-time video monitoring system for the eyes during prone surgery. Br J Anaesth (2011) 0.76
Hematology values in a colony of budgerigars (Melopsittacus undulatus) and changes associated with aging. J Nutr (1998) 0.76
Vibrio cholerae 01 strain resistant to vibriostatic compound 0/129 isolated from cholera cases in Kilifi, Kenya. East Afr Med J (2002) 0.75
Antisperm antibodies in infertility. Br Med J (Clin Res Ed) (1988) 0.75
Salicylate poisoning in children: report of three cases. East Afr Med J (2004) 0.75
Effects of hypothermia on hemodynamic responses to dopamine and dobutamine. J Trauma (1992) 0.75
Evaluation of assessment instruments used on children presenting with altered level of consciousness. East Afr Med J (2008) 0.75
Normal detrusor is more sensitive than hypertrophied detrusor to in vitro ischemia followed by re-oxygenation. Neurourol Urodyn (2000) 0.75
Graviceptor development in jellyfish ephyrae in space and on Earth. Adv Space Res (1994) 0.75
Reexamining the associate degree curriculum. Assessing the need for community concepts. Nurs Health Care Perspect (1999) 0.75