Modern quantitative acid-base chemistry.

Calculation of the equilibrium pH in a multiple-buffered aqueous solution based on partitioning of proton buffering: a new predictive formula. Am J Physiol Renal Physiol (2009) 2.26

Xylem Sap pH Increase: A Drought Signal Received at the Apoplastic Face of the Guard Cell That Involves the Suppression of Saturable Abscisic Acid Uptake by the Epidermal Symplast. Plant Physiol (1997) 1.97

Determinants of blood pH in health and disease. Crit Care (2000) 1.94

Association of Hyperchloremia With Hospital Mortality in Critically Ill Septic Patients. Crit Care Med (2015) 1.93

Extra- and Intracellular pH and Membrane Potential Changes Induced by K, Cl, H(2)PO(4), and NO(3) Uptake and Fusicoccin in Root Hairs of Limnobium stoloniferum. Plant Physiol (1990) 1.91

Lactate versus non-lactate metabolic acidosis: a retrospective outcome evaluation of critically ill patients. Crit Care (2006) 1.75

pH regulation in anoxic plants. Ann Bot (2005) 1.74

Acid-base status of critically ill patients with acute renal failure: analysis based on Stewart-Figge methodology. Crit Care (2003) 1.64

A balanced view of balanced solutions. Crit Care (2010) 1.61

Bench-to-bedside review: Chloride in critical illness. Crit Care (2010) 1.53

Nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney. Br J Nutr (2013) 1.52

Clinical use of lactate monitoring in critically ill patients. Ann Intensive Care (2013) 1.49

The meaning of acid-base abnormalities in the intensive care unit: part III -- effects of fluid administration. Crit Care (2004) 1.48

Conventional or physicochemical approach in intensive care unit patients with metabolic acidosis. Crit Care (2003) 1.45

Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis. Crit Care (2005) 1.44

Clinical review: reunification of acid-base physiology. Crit Care (2005) 1.44

System potentials, a novel electrical long-distance apoplastic signal in plants, induced by wounding. Plant Physiol (2009) 1.39

[Stewart's acid-base approach]. Wien Klin Wochenschr (2007) 1.39

The use of chloride-sodium ratio in the evaluation of metabolic acidosis in critically ill neonates. Eur J Pediatr (2012) 1.37

Electrical Membrane Properties of Leaves, Roots, and Single Root Cap Cells of Susceptible Avena sativa: Effect of Victorin C. Plant Physiol (1991) 1.28

Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions. Crit Care (2007) 1.25

The incidence and prognostic value of hypochloremia in critically ill patients. ScientificWorldJournal (2012) 1.24

Heterogeneous distribution of hydrogen and bicarbonate ions during complete brain ischemia. Prog Brain Res (1985) 1.15

Correction of the anion gap for albumin in order to detect occult tissue anions in shock. Arch Dis Child (2002) 1.13

Effects of short-term training on plasma acid-base balance during incremental exercise in man. J Physiol (2003) 1.12

Chasing the base deficit: hyperchloraemic acidosis following 0.9% saline fluid resuscitation. Arch Dis Child (2000) 1.11

Acetazolamide-mediated decrease in strong ion difference accounts for the correction of metabolic alkalosis in critically ill patients. Crit Care (2006) 1.10

Urinary strong ion difference is a major determinant of plasma chloride concentration changes in postoperative patients. Rev Bras Ter Intensiva (2013) 1.09

Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the diagnosis of hyperlactatemia. BMC Emerg Med (2008) 1.08

Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. A prospective, multiple-center study. Crit Care (2011) 1.08

Clinical review: Acid-base abnormalities in the intensive care unit -- part II. Crit Care (2004) 1.07

Clinical review: the meaning of acid-base abnormalities in the intensive care unit part I - epidemiology. Crit Care (2005) 1.02

A quantitative analysis of the acidosis of cardiac arrest: a prospective observational study. Crit Care (2005) 1.02

Hypoalbuminaemia in critically ill children: incidence, prognosis, and influence on the anion gap. Arch Dis Child (2003) 1.01

Bench-to-bedside review: lactate and the kidney. Crit Care (2002) 1.00

Year in review: Critical Care 2004 - nephrology. Crit Care (2005) 0.99

The Stewart approach--one clinician's perspective. Clin Biochem Rev (2009) 0.98

Apoplastic pH during low-oxygen stress in Barley. Ann Bot (2006) 0.97

Root-to-shoot signalling: apoplastic alkalinization, a general stress response and defence factor in barley (Hordeum vulgare). Protoplasma (2005) 0.96

Clinical applicability of functional hemodynamic monitoring. Ann Intensive Care (2011) 0.96

Association of serum chloride concentration with outcomes in postoperative critically ill patients: a retrospective observational study. J Intensive Care (2014) 0.95

Should chloride-rich crystalloids remain the mainstay of fluid resuscitation to prevent 'pre-renal' acute kidney injury?: con. Kidney Int (2014) 0.95

Physicochemical analysis of blood and urine in the course of acute kidney injury in critically ill patients: a prospective, observational study. BMC Anesthesiol (2013) 0.94

Use of sodium-chloride difference and corrected anion gap as surrogates of Stewart variables in critically ill patients. PLoS One (2013) 0.93

Why is saline so acidic (and does it really matter?). Int J Med Sci (2013) 0.92

Early diagnosis of acute kidney injury in a critically ill patient using a combination of blood and urinary physicochemical parameters. Clinics (Sao Paulo) (2012) 0.92

Hypertonic sodium lactate improves fluid balance and hemodynamics in porcine endotoxic shock. Crit Care (2014) 0.91

Bench-to-bedside review: treating acid-base abnormalities in the intensive care unit--the role of renal replacement therapy. Crit Care (2004) 0.90

Clinical review: Renal tubular acidosis--a physicochemical approach. Crit Care (2005) 0.89

Balanced versus chloride-rich solutions for fluid resuscitation in brain-injured patients: a randomised double-blind pilot study. Crit Care (2013) 0.89

Integration of acid-base and electrolyte disorders. N Engl J Med (2015) 0.89

Science review: quantitative acid-base physiology using the Stewart model. Crit Care (2004) 0.89

Hyperchloraemic metabolic acidosis following open cardiac surgery. Arch Dis Child (2005) 0.89

Comparison of lactated Ringer's solution and 0.9% saline in the treatment of rhabdomyolysis induced by doxylamine intoxication. Emerg Med J (2007) 0.87

Clinical Decision Support for Early Recognition of Sepsis. Am J Med Qual (2014) 0.87

Dissection of heat-induced systemic signals: superiority of ion fluxes to voltage changes in substomatal cavities. Planta (2008) 0.87

Closing the gap on unmeasured anions. Crit Care (2003) 0.86

Defences against ammonia toxicity in tropical air-breathing fishes exposed to high concentrations of environmental ammonia: a review. J Comp Physiol B (2004) 0.86

The standard strong ion difference, standard total titratable base, and their relationship to the Boston compensation rules and the Van Slyke equation for extracellular fluid. J Clin Monit Comput (2010) 0.85

A retrospective analysis of the haemodynamic and metabolic effects of fluid resuscitation in Vietnamese adults with severe falciparum malaria. PLoS One (2011) 0.85

Impact of Plasma-Lyte pH 7.4 on acid-base status and hemodynamics in a model of controlled hemorrhagic shock. Clinics (Sao Paulo) (2011) 0.85

Characterisation of metabolic acidosis in Kenyan children admitted to hospital for acute non-surgical conditions. Trans R Soc Trop Med Hyg (2005) 0.84

Facing acid-base disorders in the third millennium - the Stewart approach revisited. Int J Nephrol Renovasc Dis (2014) 0.84

Quantitative physico-chemical analysis of the acidosis of cardiac arrest. Crit Care (2005) 0.84

Bench-to-bedside review: a brief history of clinical acid-base. Crit Care (2004) 0.84

An analysis of renal tubular acidosis by the Stewart method. Pediatr Nephrol (2005) 0.83

Bench-to-bedside review: Fundamental principles of acid-base physiology. Crit Care (2004) 0.83

Acid-base disturbances in the emergency department: Part 1: Piecing the clues together. Can Fam Physician (1991) 0.82

Validation of a method to partition the base deficit in meningococcal sepsis: a retrospective study. Crit Care (2005) 0.82

Acid-base disorders in patients with chronic obstructive pulmonary disease: a pathophysiological review. J Biomed Biotechnol (2012) 0.82

Influence of an acetate- and a lactate-based balanced infusion solution on acid base physiology and hemodynamics: an observational pilot study. Eur J Med Res (2012) 0.81

Acute renal response to rapid onset respiratory acidosis. Can J Physiol Pharmacol (2011) 0.81

Mathematical modelling of the acid-base chemistry and oxygenation of blood: a mass balance, mass action approach including plasma and red blood cells. Eur J Appl Physiol (2009) 0.81

Metabolic Response of Maize Roots to Hyperosmotic Shock : An in VivoP Nuclear Magnetic Resonance Study. Plant Physiol (1992) 0.81

Relationship between effort sense and ventilatory response to intense exercise performed with reduced muscle glycogen. Eur J Appl Physiol (2011) 0.81

Quantitative physicochemical analysis of acid-base balance and clinical utility of anion gap and strong ion gap in 806 neonatal calves with diarrhea. J Vet Intern Med (2015) 0.81

pH regulation in anoxic rice coleoptiles at pH 3.5: biochemical pHstats and net H+ influx in the absence and presence of NOFormula. J Exp Bot (2011) 0.80

Metabolic acidosis and strong ion gap in critically ill patients with acute kidney injury. Biomed Res Int (2014) 0.79

Diabetic ketoacidosis. BMJ (2007) 0.79

Partitioning standard base excess: a new approach. J Clin Monit Comput (2011) 0.79

Model for the behaviour of compartmental CO(2) stores during incremental exercise. Eur J Appl Physiol (2004) 0.78

Acid-base chemistry of plasma: consolidation of the traditional and modern approaches from a mathematical and clinical perspective. J Clin Monit Comput (2010) 0.78

Effects of tight versus non tight control of metabolic acidosis on early renal function after kidney transplantation. Daru (2012) 0.78

Hydrogen ion concentration and coronary artery bypass graft surgery with and without cardiopulmonary bypass. J Cardiothorac Surg (2013) 0.78

Milk fever control principles: a review. Acta Vet Scand (2002) 0.78

Severe metabolic alkalosis due to the combination of unmeasured cations and hypochloraemia in a patient with gastroparesia and frequent emesis. BMJ Case Rep (2009) 0.78

Fluid resuscitation in sepsis: reexamining the paradigm. Biomed Res Int (2014) 0.78

Characterization of acid-base status in maintenance hemodialysis: physicochemical approach. J Artif Organs (2008) 0.78

Evaluation of pulmonary dysfunctions and acid-base imbalances induced by Chlamydia psittaci in a bovine model of respiratory infection. Multidiscip Respir Med (2014) 0.77

Has Stewart approach improved our ability to diagnose acid-base disorders in critically ill patients? World J Crit Care Med (2015) 0.77

Intracellular [H+]: a determinant of cell volume in skeletal muscle. J Physiol (2005) 0.76

Fluid and ion transfer across the blood-brain and blood-cerebrospinal fluid barriers; a comparative account of mechanisms and roles. Fluids Barriers CNS (2016) 0.76

Hypercapnic respiratory acidosis: a protective or harmful strategy for critically ill newborn foals? Can J Vet Res (2012) 0.76

Evaluation of the efficacy of simplified Fencl-Stewart equation in analyzing the changes in acid base status following resuscitation with two different fluids. Int J Crit Illn Inj Sci (2013) 0.75

Chloride alterations in hospitalized patients: Prevalence and outcome significance. PLoS One (2017) 0.75

The importance of the ionic product for water to understand the physiology of the acid-base balance in humans. Biomed Res Int (2014) 0.75

Effect of the independent acid base variables on anion gap variation in cardiac surgical patients: a Stewart-Figge approach. ScientificWorldJournal (2014) 0.75

The Significance of Strong Ion Gap for Predicting Return of Spontaneous Circulation in Patients with Cardiopulmonary Arrest. Open Med (Wars) (2017) 0.75

What's New in Critical Illness and Injury Science? The ongoing debate on the optimal resuscitative fluid and monitoring parameters. Int J Crit Illn Inj Sci (2013) 0.75

Acid-base changes after fluid bolus: sodium chloride vs. sodium octanoate. Intensive Care Med Exp (2013) 0.75

Mortality of U.S. embalmers and funeral directors. Am J Ind Med (1990) 2.35

Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: a study using quail--chick transplantation chimeras. Dev Biol (1981) 2.24

Modelling the use of health services by populations of small areas to inform the allocation of central resources to larger regions. Socioecon Plann Sci (1992) 1.80

Independent and dependent variables of acid-base control. Respir Physiol (1978) 1.60

Doppler ultrasound assessment of cerebral blood flow in the human fetus. Br J Obstet Gynaecol (1986) 1.58

Cancer and other causes of death among a cohort of dry cleaners. Br J Ind Med (1990) 1.56

Treatment of fetal cardiac arrhythmias. Br J Hosp Med (1985) 1.55

Parental occupational lead exposure and low birth weight. Am J Ind Med (1996) 1.51

Differential permeability of endothelial and epithelial barriers to albumin flux. J Appl Physiol Respir Environ Exerc Physiol (1979) 1.51

Prenatal diagnosis of spina bifida aperta after first-trimester valproate exposure. Prenat Diagn (1992) 1.50

Occupational exposure to chlorinated aliphatic hydrocarbons and risk of astrocytic brain cancer. Am J Ind Med (1994) 1.48

Brain tumor mortality risk among men with electrical and electronics jobs: a case-control study. J Natl Cancer Inst (1987) 1.46

Mortality and cancer incidence of aircraft maintenance workers exposed to trichloroethylene and other organic solvents and chemicals: extended follow up. Occup Environ Med (1998) 1.46

The risk of spina bifida aperta after first-trimester exposure to valproate in a prenatal cohort. Neurology (1992) 1.43

The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy. Ultrasound Med Biol (1988) 1.42

Endoscopic localization prior to partial cystectomy. Br J Urol (1994) 1.38

Occupational case-control studies: I. Collecting information on work histories and work-related exposures. Am J Ind Med (1994) 1.36

Evaluation of risks for non-Hodgkin's lymphoma by occupation and industry exposures from a case-control study. Am J Ind Med (1993) 1.29

Occupational exposure to formaldehyde and wood dust and nasopharyngeal carcinoma. Occup Environ Med (2000) 1.27

Occupational exposure to chlorinated aliphatic hydrocarbons: job exposure matrix. Am J Ind Med (1994) 1.26

Retrospective cohort mortality study of workers at an aircraft maintenance facility. I. Epidemiological results. Br J Ind Med (1991) 1.20

Petroleum-related employment and renal cell cancer. J Occup Med (1985) 1.11

Epidemiologic evidence on the relationship between formaldehyde exposure and cancer. Scand J Work Environ Health (1990) 1.10

Delayed dehiscence of repaired bladder rupture. Urol Int (1992) 1.09

Mortality from lung cancer and respiratory disease among pottery workers exposed to silica and talc. Am J Epidemiol (1987) 1.08

Do quantitative exposure assessments improve risk estimates in occupational studies of cancer? Am J Ind Med (1992) 1.08

Efficacy of routine fetal ultrasound screening for congenital heart disease in normal pregnancy. Circulation (1996) 1.08

Interendothelial junctional changes underlie the developmental 'tightening' of the blood-brain barrier. Brain Res (1987) 1.06

The efficacy of flecainide versus digoxin in the management of fetal supraventricular tachycardia. Prenat Diagn (1995) 1.05

Effects of three features of a job-exposure matrix on risk estimates. Epidemiology (1994) 1.04

A new glioma model in rat: the C6 spheroid implantation technique permeability and vascular characterization. J Neurooncol (1987) 1.03

Occupational exposures and female breast cancer mortality in the United States. J Occup Environ Med (1995) 1.03

Clinical significance of maternal anti-Ro/SS-A antibodies in children with isolated heart block. J Am Coll Cardiol (1994) 1.01

Time course of radiation-induced apoptosis in the adult rat spinal cord. Radiother Oncol (1996) 1.01

Mortality of industrial workers exposed to acrylonitrile. Scand J Work Environ Health (1998) 1.00

Fetal cardiac arrhythmias and their effect on volume blood flow in descending aorta of human fetus. J Clin Ultrasound (1986) 0.99

Prenatal diagnosis by ultrasound in pregnancies at risk for autosomal recessive polycystic kidney disease. Ultrasound Med Biol (1990) 0.98

Risk of astrocytic brain tumors associated with occupational chemical exposures. A case-referent study. Scand J Work Environ Health (1987) 0.98

Occupation and leukemia: a population-based case-control study in Iowa and Minnesota. Am J Ind Med (2001) 0.98

Occupational exposure to pesticides and pancreatic cancer. Am J Ind Med (2001) 0.97

Arrhythmia and structural abnormalities of the fetal heart. Br Heart J (1983) 0.97

Morphometric analysis of CNS microvascular endothelium. Microvasc Res (1985) 0.97

Mortality experience of haematite mine workers in China. Br J Ind Med (1990) 0.97

Barrier properties of testis microvessels. Proc Natl Acad Sci U S A (1993) 0.95

Occupational risk factors for laryngeal cancer on the Texas Gulf Coast. Cancer Res (1988) 0.95

A quantitative analysis of blood-brain barrier ultrastructure in the aging human. Microvasc Res (1987) 0.95

Risk for prostate cancer by occupation and industry: a 24-state death certificate study. Am J Ind Med (1998) 0.94

Microcephaly, micrognathia, and bird-headed dwarfism: prenatal diagnosis of a Seckel-like syndrome. Am J Med Genet (1987) 0.92

Three-dimensional reconstruction of vesicles in endothelium of blood-brain barrier versus highly permeable microvessels. Anat Rec (1986) 0.92

Cancers of the nasopharynx and oropharynx and formaldehyde exposure. J Natl Cancer Inst (1987) 0.91

Occupation and the risk of adult glioma in the United States. Cancer Causes Control (2003) 0.90

Ductus venosus blood flow velocity waveforms in the human fetus--a Doppler study. Ultrasound Med Biol (1992) 0.90

Quantitative morphology of human glioblastoma multiforme microvessels: structural basis of blood-brain barrier defect. J Neurooncol (1987) 0.89

The relationship of astrocyte-like cells to the vessels that contribute to the blood-ocular barriers. Brain Res (1993) 0.89

Efficacy of fetal echocardiography and yield by risk category. Obstet Gynecol (1996) 0.88

Work in dry cleaning and the incidence of cancer of the oral cavity, larynx, and oesophagus. Occup Environ Med (1997) 0.88

An experimental design approach to retrospective exposure assessment. Am Ind Hyg Assoc J (1996) 0.88

Non-invasive management of fetal obstructive uropathy. Lancet (1988) 0.87

"Offsetting" of the septal tricuspid leaflet in normal hearts and in hearts with Ebstein's anomaly. Anatomic and echographic correlation. Am J Cardiol (1984) 0.85

Cardiac and extra-cardiac anomalies as indicators for trisomies 13 and 18: a prenatal ultrasound study. Prenat Diagn (1989) 0.84

Determining the probability of pesticide exposures among migrant farmworkers: results from a feasibility study. Am J Ind Med (2001) 0.84

Pericytes in human cerebral microvasculature. Anat Rec (1987) 0.84

A novel strategy for NQO1 (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) mediated therapy of bladder cancer based on the pharmacological properties of EO9. Br J Cancer (2001) 0.83

A quantitative assessment of microvessel ultrastructure in C6 astrocytoma spheroids transplanted to brain and to muscle. J Neuropathol Exp Neurol (1988) 0.83

Comments on occupational and environmental factors in the origin of non-Hodgkin's lymphoma. Cancer Res (1992) 0.83

Traumatic rupture of the testis. Br J Urol (1988) 0.83

Mortality from lung cancer among workers employed in formaldehyde industries. Am J Ind Med (1990) 0.83

Left atrial isomerism associated with asplenia: prenatal echocardiographic detection of complex congenital cardiac malformations. J Am Coll Cardiol (1984) 0.83

Validity of exposure in one job as a surrogate for exposure in a cohort study. Am J Ind Med (1993) 0.83

A philosophy for dealing with hypothesized uncontrolled confounding in epidemiological investigations. Med Lav (1995) 0.83

Occupational epidemiologic study design and application. Occup Med (1997) 0.82

Fetal cystic hygroma: prenatal diagnosis and management. Obstet Gynecol (1988) 0.82

Fetal cardiac flow velocities in the late 1st trimester of pregnancy: a transvaginal Doppler study. J Am Coll Cardiol (1991) 0.82

Maternal autoantibodies and congenital heart block: no evidence for the existence of a unique heart block-associated anti-Ro/SS-A autoantibody profile. Lupus (1993) 0.82

Re-evaluating the role of astrocytes in blood-brain barrier induction. Dev Dyn (1993) 0.82

A survey of the management of neuromuscular blockade monitoring in Australia and New Zealand. Anaesth Intensive Care (2013) 0.81

Prenatal diagnosis of Klippel-Trenaunay-Weber syndrome: a case report. Ultrasound Obstet Gynecol (1992) 0.81

The functional microcirculation in a glioma model. Int J Radiat Biol (1991) 0.80

Reexamination of Stewart's quantitative analysis of acid-base status. Med Sci Sports Exerc (1991) 0.80

Ultrasound in urological emergency: results of self audit and implications for training. Int Urol Nephrol (1996) 0.80

Fetal cardiovascular dynamics during cardiac dysrhythmia. Case report. Br J Obstet Gynaecol (1983) 0.80

A quantitative study of blood-brain barrier permeability ultrastructure in a new rat glioma model. Acta Neuropathol (1985) 0.80

Prenatal diagnosis of congenital diaphragmatic hernia: a retrospective analysis of 28 cases. Prenat Diagn (1994) 0.80

Fetal renal anomalies, a diagnostic dilemma in the presence of intrauterine growth retardation and oligohydramnios. Ultrasound Med Biol (1987) 0.79

Preterm delivery rate and fetal outcome in structurally affected twin pregnancies: a retrospective matched control study. Prenat Diagn (1993) 0.79

Correlation between different measures of occupational exposure to formaldehyde. Am J Epidemiol (1990) 0.79

Intracerebral, aortic, and umbilical artery flow velocity waveforms in the late-first-trimester fetus. Am J Obstet Gynecol (1992) 0.79

Structural and histochemical features of the avian blood-brain barrier. J Comp Neurol (1981) 0.79

Cancer and other mortality patterns among United States furniture workers. Br J Ind Med (1989) 0.79

Blood pressure estimation in the human fetal descending aorta. Ultrasound Obstet Gynecol (2008) 0.79

Revascularization of skin transplanted into the brain: source of the graft endothelium. Microvasc Res (1984) 0.79

Severe intrauterine growth retardation; assessment of its origin from fetal arterial flow velocity waveforms. Eur J Obstet Gynecol Reprod Biol (1986) 0.78

Oligohydramnios and fetal cerebral blood flow. Br J Obstet Gynaecol (1988) 0.78

Fetal hydrocephaly: diagnosis, prognosis and management. Ultrasound Med Biol (1986) 0.78

Temperature dependence on the passive and dynamic electrical parameters of muscle cells. Acta Physiol Lat Am (1979) 0.78

The role of urodynamics in female urinary stress incontinence. Br J Urol (1987) 0.78

Human fetal foramen ovale flow velocity waveforms relative to behavioral states in normal term pregnancy. Am J Obstet Gynecol (1990) 0.78

Creatine kinase isozyme transition in chicks with hereditary muscular dystrophy. Muscle Nerve (1981) 0.78

Fetal cardiac structure and function as studied by ultrasound. Clin Cardiol (1984) 0.78

The role of diagnostic ultrasound in the study of fetal cardiac abnormalities. Ultrasound Med Biol (1985) 0.78