Published in Nat Genet on October 30, 2005
The biology of infertility: research advances and clinical challenges. Nat Med (2008) 4.62
Human aneuploidy: mechanisms and new insights into an age-old problem. Nat Rev Genet (2012) 2.96
Genetics of mammalian meiosis: regulation, dynamics and impact on fertility. Nat Rev Genet (2010) 2.58
Evidence that weakened centromere cohesion is a leading cause of age-related aneuploidy in oocytes. Curr Biol (2010) 2.44
Bisphenol A exposure in utero disrupts early oogenesis in the mouse. PLoS Genet (2007) 2.33
Oocyte-specific differences in cell-cycle control create an innate susceptibility to meiotic errors. Curr Biol (2011) 2.30
The consequences of asynapsis for mammalian meiosis. Nat Rev Genet (2009) 2.29
Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes. Genes Dev (2010) 2.04
Age-associated increase in aneuploidy and changes in gene expression in mouse eggs. Dev Biol (2008) 1.85
Maternal age and chromosomally abnormal pregnancies: what we know and what we wish we knew. Curr Opin Pediatr (2009) 1.65
Geometry and force behind kinetochore orientation: lessons from meiosis. Nat Rev Mol Cell Biol (2012) 1.55
Meiotic origins of maternal age-related aneuploidy. Biol Reprod (2012) 1.52
Shugoshin-2 is essential for the completion of meiosis but not for mitotic cell division in mice. Genes Dev (2008) 1.49
Cohesin Smc1beta determines meiotic chromatin axis loop organization. J Cell Biol (2008) 1.46
RAD21L, a novel cohesin subunit implicated in linking homologous chromosomes in mammalian meiosis. J Cell Biol (2011) 1.46
Csm4, in collaboration with Ndj1, mediates telomere-led chromosome dynamics and recombination during yeast meiosis. PLoS Genet (2008) 1.43
Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis. PLoS Genet (2010) 1.42
Oocyte cohesin expression restricted to predictyate stages provides full fertility and prevents aneuploidy. Curr Biol (2010) 1.39
Apoptosis maintains oocyte quality in aging Caenorhabditis elegans females. PLoS Genet (2008) 1.38
The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility. EMBO J (2011) 1.34
Age-related aneuploidy through cohesion exhaustion. EMBO Rep (2012) 1.31
Aging predisposes oocytes to meiotic nondisjunction when the cohesin subunit SMC1 is reduced. PLoS Genet (2008) 1.25
Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I. J Cell Sci (2009) 1.24
The diverse roles of transverse filaments of synaptonemal complexes in meiosis. Chromosoma (2006) 1.24
Chromosome cohesion decreases in human eggs with advanced maternal age. Aging Cell (2012) 1.24
Coupling meiotic chromosome axis integrity to recombination. Genes Dev (2008) 1.23
Maternal age and risk for trisomy 21 assessed by the origin of chromosome nondisjunction: a report from the Atlanta and National Down Syndrome Projects. Hum Genet (2008) 1.22
Cohesin SMC1beta protects telomeres in meiocytes. J Cell Biol (2009) 1.22
The Y-encoded gene zfy2 acts to remove cells with unpaired chromosomes at the first meiotic metaphase in male mice. Curr Biol (2011) 1.22
Mutant cohesin in premature ovarian failure. N Engl J Med (2014) 1.20
Dissecting the mammalian synaptonemal complex using targeted mutations. Chromosome Res (2007) 1.18
ZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing over. PLoS Genet (2008) 1.18
Meikin is a conserved regulator of meiosis-I-specific kinetochore function. Nature (2014) 1.14
Emerging roles for centromeres in meiosis I chromosome segregation. Nat Rev Genet (2008) 1.14
The pch2Delta mutation in baker's yeast alters meiotic crossover levels and confers a defect in crossover interference. PLoS Genet (2009) 1.13
Bivalent separation into univalents precedes age-related meiosis I errors in oocytes. Nat Commun (2015) 1.06
Aging (not so) gracefully. Nat Genet (2005) 1.03
Mechanisms of aneuploidy. Curr Opin Cell Biol (2011) 1.01
Shaping meiotic prophase chromosomes: cohesins and synaptonemal complex proteins. Chromosoma (2006) 1.00
Age-dependent susceptibility of chromosome cohesion to premature separase activation in mouse oocytes. Biol Reprod (2011) 1.00
Control of oocyte growth and meiotic maturation in Caenorhabditis elegans. Adv Exp Med Biol (2013) 1.00
Genetic evidence that synaptonemal complex axial elements govern recombination pathway choice in mice. Genetics (2011) 0.99
Portrait of an oocyte: our obscure origin. J Clin Invest (2010) 0.97
Meiosis and maternal aging: insights from aneuploid oocytes and trisomy births. Cold Spring Harb Perspect Biol (2015) 0.97
Mutations of the SYCP3 gene in women with recurrent pregnancy loss. Am J Hum Genet (2008) 0.96
Age-dependent recombination rates in human pedigrees. PLoS Genet (2011) 0.95
Heterozygosity for a Bub1 mutation causes female-specific germ cell aneuploidy in mice. Proc Natl Acad Sci U S A (2009) 0.95
DNA damage-induced metaphase I arrest is mediated by the spindle assembly checkpoint and maternal age. Nat Commun (2015) 0.93
Complex elaboration: making sense of meiotic cohesin dynamics. FEBS J (2015) 0.93
Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet (2014) 0.92
Altered cohesin gene dosage affects Mammalian meiotic chromosome structure and behavior. PLoS Genet (2013) 0.92
Domain-specific regulation of recombination in Caenorhabditis elegans in response to temperature, age and sex. Genetics (2008) 0.92
The spindle checkpoint and chromosome segregation in meiosis. FEBS J (2015) 0.91
Preconception folic acid supplementation and risk for chromosome 21 nondisjunction: a report from the National Down Syndrome Project. Am J Med Genet A (2013) 0.90
Meiotic cohesin SMC1β provides prophase I centromeric cohesion and is required for multiple synapsis-associated functions. PLoS Genet (2013) 0.90
Arrested human embryos are more likely to have abnormal chromosomes than developing embryos from women of advanced maternal age. J Ovarian Res (2014) 0.88
Trisomic pregnancy and elevated FSH: implications for the oocyte pool hypothesis. Hum Reprod (2011) 0.87
Mouse oocytes depend on BubR1 for proper chromosome segregation but not for prophase I arrest. Nat Commun (2015) 0.87
Germline mosaicism does not explain the maternal age effect on trisomy. Am J Med Genet A (2013) 0.86
Spindle assembly in the oocytes of mouse and Drosophila--similar solutions to a problem. Chromosome Res (2007) 0.85
An algorithm for determining the origin of trisomy and the positions of chiasmata from SNP genotype data. Chromosome Res (2011) 0.85
Oocyte maturation failure: a syndrome of bad eggs. Fertil Steril (2010) 0.84
Oocyte development, meiosis and aneuploidy. Semin Cell Dev Biol (2015) 0.83
Rejuvenation of meiotic cohesion in oocytes during prophase I is required for chiasma maintenance and accurate chromosome segregation. PLoS Genet (2014) 0.83
Cohesin loading factor Nipbl localizes to chromosome axes during mammalian meiotic prophase. Cell Div (2013) 0.82
The roles of cohesins in mitosis, meiosis, and human health and disease. Methods Mol Biol (2014) 0.82
Cohesin proteins load sequentially during prophase I in tomato primary microsporocytes. Chromosome Res (2011) 0.82
Identification of heat shock factor 1 molecular and cellular targets during embryonic and adult female meiosis. Mol Cell Biol (2011) 0.82
Transmission of Y chromosomes from XY female mice was made possible by the replacement of cytoplasm during oocyte maturation. Proc Natl Acad Sci U S A (2008) 0.82
Heterochromatin-mediated association of achiasmate homologs declines with age when cohesion is compromised. Genetics (2009) 0.82
Genetic Interactions Between the Meiosis-Specific Cohesin Components, STAG3, REC8, and RAD21L. G3 (Bethesda) (2016) 0.79
Oocyte Maturation and Development. F1000Res (2016) 0.79
Fer tyrosine kinase is required for germinal vesicle breakdown and meiosis-I in mouse oocytes. Mol Reprod Dev (2011) 0.79
Deterioration without replenishment--the misery of oocyte cohesin. Genes Dev (2010) 0.79
Heterochromatin-Associated Proteins HP1a and Piwi Collaborate to Maintain the Association of Achiasmate Homologs in Drosophila Oocytes. Genetics (2016) 0.78
Separase phosphosite mutation leads to genome instability and primordial germ cell depletion during oogenesis. PLoS One (2011) 0.78
The association between the oocyte pool and aneuploidy: a comparative study of the reproductive potential of young and aged mice. J Assist Reprod Genet (2013) 0.78
Chromosome Cohesion Established by Rec8-Cohesin in Fetal Oocytes Is Maintained without Detectable Turnover in Oocytes Arrested for Months in Mice. Curr Biol (2016) 0.78
Cohesin in oocytes-tough enough for Mammalian meiosis? Genes (Basel) (2010) 0.77
Cohesin axis maturation and presence of RAD51 during first meiotic prophase in a true bug. Chromosoma (2009) 0.77
Scrambling eggs in plastic bottles. PLoS Genet (2007) 0.76
Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes. Elife (2016) 0.76
Merotelic kinetochore attachment in oocyte meiosis II causes sister chromatids segregation errors in aged mice. Cell Cycle (2017) 0.76
Smc1β is required for activation of SAC during mouse oocyte meiosis. Cell Cycle (2017) 0.75
Meiosis I in Xenopus oocytes is not error-prone despite lacking spindle assembly checkpoint. Cell Cycle (2014) 0.75
Telomere homeostasis in mammalian germ cells: a review. Chromosoma (2015) 0.75
The rate of meiotic gene conversion varies by sex and age. Nat Genet (2016) 0.75
Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1. Sci Rep (2017) 0.75
Elevated intracellular pH appears in aged oocytes and causes oocyte aneuploidy associated with the loss of cohesion in mice. Cell Cycle (2016) 0.75
Oxidative stress in oocytes during midprophase induces premature loss of cohesion and chromosome segregation errors. Proc Natl Acad Sci U S A (2016) 0.75
The association of low socioeconomic status and the risk of having a child with Down syndrome: a report from the National Down Syndrome Project. Genet Med (2013) 0.75
Structural Maintenance of Chromosomes protein 1: Role in Genome Stability and Tumorigenesis. Int J Biol Sci (2017) 0.75
Age-Related Loss of Cohesion: Causes and Effects. Int J Mol Sci (2017) 0.75
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol (2006) 5.00
Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reprod Toxicol (2007) 4.04
B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity (2006) 4.04
Bisphenol a exposure causes meiotic aneuploidy in the female mouse. Curr Biol (2003) 3.93
Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response. Immunity (2009) 3.32
Why public health agencies cannot depend on good laboratory practices as a criterion for selecting data: the case of bisphenol A. Environ Health Perspect (2008) 3.27
Sex matters in meiosis. Science (2002) 2.98
Human aneuploidy: mechanisms and new insights into an age-old problem. Nat Rev Genet (2012) 2.96
Human female meiosis: what makes a good egg go bad? Trends Genet (2008) 2.91
Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice. Proc Natl Acad Sci U S A (2008) 2.91
Cohesin SMC1 beta is required for meiotic chromosome dynamics, sister chromatid cohesion and DNA recombination. Nat Cell Biol (2004) 2.79
Similarity of bisphenol A pharmacokinetics in rhesus monkeys and mice: relevance for human exposure. Environ Health Perspect (2010) 2.62
Covariation of synaptonemal complex length and mammalian meiotic exchange rates. Science (2002) 2.54
Bisphenol A exposure in utero disrupts early oogenesis in the mouse. PLoS Genet (2007) 2.33
Meiotic cohesin REC8 marks the axial elements of rat synaptonemal complexes before cohesins SMC1beta and SMC3. J Cell Biol (2003) 2.23
Age-related meiotic segregation errors in mammalian oocytes are preceded by depletion of cohesin and Sgo2. Curr Biol (2010) 2.17
SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. Nature (2002) 2.08
Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice. Mol Cell (2003) 2.08
Genetic control of mammalian meiotic recombination. I. Variation in exchange frequencies among males from inbred mouse strains. Genetics (2002) 1.90
An evaluation of evidence for the carcinogenic activity of bisphenol A. Reprod Toxicol (2007) 1.83
Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression. Curr Biol (2009) 1.81
Gene expression in the fetal mouse ovary is altered by exposure to low doses of bisphenol A. Biol Reprod (2010) 1.80
Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome. Hum Mol Genet (2005) 1.67
Bisphenol a and reproductive health: update of experimental and human evidence, 2007-2013. Environ Health Perspect (2014) 1.61
Human exposures to bisphenol A: mismatches between data and assumptions. Rev Environ Health (2013) 1.59
Predicting meiotic pathways in human fetal oogenesis. Biol Reprod (2009) 1.48
Cohesin Smc1beta determines meiotic chromatin axis loop organization. J Cell Biol (2008) 1.46
Oocyte cohesin expression restricted to predictyate stages provides full fertility and prevents aneuploidy. Curr Biol (2010) 1.39
Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA. Hum Mol Genet (2008) 1.37
Precise hit: adeno-associated virus in gene targeting. Nat Rev Microbiol (2005) 1.36
Simultaneous analysis of chromosomes and chromosome-associated proteins in mammalian oocytes and embryos. Chromosoma (2002) 1.28
SYCP2 and SYCP3 are required for cohesin core integrity at diplotene but not for centromere cohesion at the first meiotic division. J Cell Sci (2005) 1.27
Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs. Nat Immunol (2006) 1.26
The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis. Curr Biol (2007) 1.23
Cohesin SMC1beta protects telomeres in meiocytes. J Cell Biol (2009) 1.22
Oxidative metabolism of pyruvate is required for meiotic maturation of murine oocytes in vivo. Biol Reprod (2007) 1.22
Bisphenol A alters the development of the rhesus monkey mammary gland. Proc Natl Acad Sci U S A (2012) 1.21
SMC1 coordinates DNA double-strand break repair pathways. Nucleic Acids Res (2004) 1.19
Meiotic recombination in human oocytes. PLoS Genet (2009) 1.15
The bisphenol A experience: a primer for the analysis of environmental effects on mammalian reproduction. Biol Reprod (2009) 1.14
DNA interaction and dimerization of eukaryotic SMC hinge domains. J Biol Chem (2004) 1.12
Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring. Nat Med (2002) 1.12
Homologous recombination is required for AAV-mediated gene targeting. Nucleic Acids Res (2006) 1.11
Bisphenol-A (BPA), BPA glucuronide, and BPA sulfate in midgestation umbilical cord serum in a northern and central California population. Environ Sci Technol (2013) 1.11
SWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migration. Mol Cell Biol (2004) 1.10
Meiotic synapsis proceeds from a limited number of subtelomeric sites in the human male. Am J Hum Genet (2005) 1.09
Bisphenol A effects on the growing mouse oocyte are influenced by diet. Biol Reprod (2009) 1.06
HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. EMBO J (2013) 1.04
Mixtures of ionic liquids. Chem Soc Rev (2012) 1.02
Near-human aneuploidy levels in female mice with homeologous chromosomes. Curr Biol (2006) 1.02
SYK regulates B-cell migration by phosphorylation of the F-actin interacting protein SWAP-70. Blood (2010) 1.00
Shaping meiotic prophase chromosomes: cohesins and synaptonemal complex proteins. Chromosoma (2006) 1.00
Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research. Toxicol Sci (2010) 0.99
BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes. J Cell Sci (2009) 0.98
Fertilization in vitro increases non-disjunction during early cleavage divisions in a mouse model system. Hum Reprod (2002) 0.98
Of mice and (wo)men: purified oogonial stem cells from mouse and human ovaries. Biol Reprod (2012) 0.98
Sphingosine 1-phosphate-induced motility and endocytosis of dendritic cells is regulated by SWAP-70 through RhoA. J Immunol (2011) 0.97
The role of osteoclast-associated receptor in osteoimmunology. J Immunol (2011) 0.97
Cohesin in determining chromosome architecture. Exp Cell Res (2012) 0.96
Dual regulation of IRF4 function in T and B cells is required for the coordination of T-B cell interactions and the prevention of autoimmunity. J Exp Med (2012) 0.93
Cohesin in gametogenesis. Curr Top Dev Biol (2013) 0.92
The synaptonemal complex and meiotic recombination in humans: new approaches to old questions. Chromosoma (2006) 0.92
Altered cohesin gene dosage affects Mammalian meiotic chromosome structure and behavior. PLoS Genet (2013) 0.92
SWAP-70-deficient mast cells are impaired in development and IgE-mediated degranulation. Eur J Immunol (2002) 0.92
Cisplatin disrupts mammalian spermatogenesis, but does not affect recombination or chromosome segregation. Mutat Res (2004) 0.91
Invalid controls undermine conclusions of FDA studies. Toxicol Sci (2014) 0.91
SWAP-70 regulates RhoA/RhoB-dependent MHCII surface localization in dendritic cells. Blood (2008) 0.91
The origin of trisomy 13. Am J Med Genet A (2007) 0.91
Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes. J Cell Sci (2013) 0.90
Regulation of eosinophil trafficking by SWAP-70 and its role in allergic airway inflammation. J Immunol (2011) 0.90
Bypassing a highly unstable frustrated Lewis pair: dihydrogen cleavage by a thermally robust silylium-phosphine adduct. Chem Commun (Camb) (2014) 0.89
Regulation of bone mass and osteoclast function depend on the F-actin modulator SWAP-70. J Bone Miner Res (2012) 0.88
SWAP-70 controls formation of the splenic marginal zone through regulating T1B-cell differentiation. Eur J Immunol (2010) 0.88
SWAP-70 regulates erythropoiesis by controlling α4 integrin. Haematologica (2011) 0.88
Sex-specific differences in meiotic chromosome segregation revealed by dicentric bridge resolution in mice. Genetics (2002) 0.88
Cohesin complexes get more complex: the novel kleisin RAD21L. Cell Cycle (2011) 0.87
The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics. J Biol Chem (2013) 0.87
Fine tuning of IRF-4 expression by SWAP-70 controls the initiation of plasma cell development. Eur J Immunol (2011) 0.86
SWAP-70 deficiency causes high-affinity plasma cell generation despite impaired germinal center formation. Blood (2007) 0.85
An algorithm for determining the origin of trisomy and the positions of chiasmata from SNP genotype data. Chromosome Res (2011) 0.85
Nondisjunction--a view from ringside. N Engl J Med (2004) 0.83
A novel resorption assay for osteoclast functionality based on an osteoblast-derived native extracellular matrix. J Cell Biochem (2010) 0.83
Dendritic cell podosome dynamics does not depend on the F-actin regulator SWAP-70. PLoS One (2013) 0.82