Published in Nat Immunol on November 06, 2005
Hyaluronan as an immune regulator in human diseases. Physiol Rev (2011) 2.74
The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils. Blood (2010) 1.68
The regulation of mRNA stability in mammalian cells: 2.0. Gene (2012) 1.46
Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy. J Clin Invest (2008) 1.37
The role of AUF1 in regulated mRNA decay. Wiley Interdiscip Rev RNA (2011) 1.34
The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation. Nat Immunol (2009) 1.29
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J Clin Invest (2008) 1.28
Identification of a signature motif in target mRNAs of RNA-binding protein AUF1. Nucleic Acids Res (2008) 1.25
Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation. Aging (Albany NY) (2009) 1.20
Post-transcriptional control of gene expression by AUF1: mechanisms, physiological targets, and regulation. Biochim Biophys Acta (2012) 1.16
Noncoding RNA and its associated proteins as regulatory elements of the immune system. Nat Immunol (2014) 1.15
Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity. Nat Immunol (2011) 1.14
Pin1 deficiency causes endothelial dysfunction and hypertension. Hypertension (2011) 1.13
FRET-detectable interactions between the ARE binding proteins, HuR and p37AUF1. RNA (2007) 1.08
Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1. Front Biosci (Landmark Ed) (2011) 1.06
The peptidyl-prolyl isomerase Pin1 determines parathyroid hormone mRNA levels and stability in rat models of secondary hyperparathyroidism. J Clin Invest (2009) 1.01
Pin1 and PKMzeta sequentially control dendritic protein synthesis. Sci Signal (2010) 1.00
Human immunodeficiency virus type 1 replication and regulation of APOBEC3G by peptidyl prolyl isomerase Pin1. J Virol (2008) 1.00
Role of CD151, A tetraspanin, in porcine reproductive and respiratory syndrome virus infection. Virol J (2007) 0.97
Pin1 modulates the type 1 immune response. PLoS One (2007) 0.95
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function. Proc Natl Acad Sci U S A (2012) 0.94
The prolyl isomerase Pin1 targets stem-loop binding protein (SLBP) to dissociate the SLBP-histone mRNA complex linking histone mRNA decay with SLBP ubiquitination. Mol Cell Biol (2012) 0.94
Eosinophil-derived cytokines in health and disease: unraveling novel mechanisms of selective secretion. Allergy (2013) 0.93
AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability. Mol Cell Biol (2006) 0.90
Pin1 protein regulates Smad protein signaling and pulmonary fibrosis. J Biol Chem (2012) 0.85
Signaling pathways that control mRNA turnover. Cell Signal (2013) 0.84
Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils. J Immunol (2013) 0.84
The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteins. PLoS One (2014) 0.84
Hsp27 and F-box protein β-TrCP promote degradation of mRNA decay factor AUF1. Mol Cell Biol (2013) 0.83
Pin1 null mice exhibit low bone mass and attenuation of BMP signaling. PLoS One (2013) 0.82
Pin1 regulates parathyroid hormone mRNA stability. J Clin Invest (2009) 0.81
Pin1: a proline isomerase that makes you wheeze? Nat Immunol (2005) 0.81
Fractalkine (CX3CL1), GM-CSF and VEGF-a levels are reduced by statins in adult patients. Clin Transl Med (2014) 0.79
AUF1 regulation of coding and noncoding RNA. Wiley Interdiscip Rev RNA (2016) 0.78
Roles of Prolyl Isomerases in RNA-Mediated Gene Expression. Biomolecules (2015) 0.78
Regulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1. Biomolecules (2015) 0.77
The prolyl isomerase Pin1 modulates development of CD8+ cDC in mice. PLoS One (2012) 0.75
Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability. Sci Rep (2016) 0.75
Protein Translation and Signaling in Human Eosinophils. Front Med (Lausanne) (2017) 0.75
Functions of tissue-resident eosinophils. Nat Rev Immunol (2017) 0.75
Epstein-Barr Virus Induced Gene 2 (EBI2) Mediates Allergen-induced, Leukocyte Migration into Airways. Am J Respir Crit Care Med (2017) 0.75
Pin1-Targeted Therapy for Systemic Lupus Erythematosus. Arthritis Rheumatol (2016) 0.75
The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95. Proc Natl Acad Sci U S A (2003) 2.82
FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol (2007) 2.75
Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study. Blood (2008) 2.00
The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils. Blood (2010) 1.68
A critical role for Pin1 in allergic pulmonary eosinophilia in rats. J Allergy Clin Immunol (2007) 1.58
beta-Amyloid degradation and Alzheimer's disease. J Biomed Biotechnol (2006) 1.35
The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation. Nat Immunol (2009) 1.29
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J Clin Invest (2008) 1.28
Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice. PLoS One (2011) 1.15
The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes. J Immunol (2006) 1.07
Pin1 and PKMzeta sequentially control dendritic protein synthesis. Sci Signal (2010) 1.00
Seizure susceptibility and mortality in mice that over-express amyloid precursor protein. Int J Clin Exp Pathol (2008) 1.00
RhoB mRNA is stabilized by HuR after UV light. Oncogene (2005) 0.99
Expression of interleukin-5- and granulocyte macrophage-colony-stimulating factor-responsive genes in blood and airway eosinophils. Am J Respir Cell Mol Biol (2003) 0.98
Decoy mRNAs reduce beta-amyloid precursor protein mRNA in neuronal cells. Neurobiol Aging (2006) 0.97
Pin1 modulates the type 1 immune response. PLoS One (2007) 0.95
Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function. Proc Natl Acad Sci U S A (2012) 0.94
Whisker stimulation-dependent translation of FMRP in the barrel cortex requires activation of type I metabotropic glutamate receptors. Brain Res Mol Brain Res (2003) 0.93
Tissue transglutaminase, protein cross-linking and Alzheimer's disease: review and views. Int J Clin Exp Pathol (2008) 0.90
Identification of genes expressed by human airway eosinophils after an in vivo allergen challenge. PLoS One (2013) 0.90
Alzheimer's disease and Down syndrome rodent models exhibit audiogenic seizures. J Alzheimers Dis (2010) 0.90
Potent synergistic effect of IL-3 and TNF on matrix metalloproteinase 9 generation by human eosinophils. Cytokine (2012) 0.90
Ets-1 regulates TNF-alpha-induced matrix metalloproteinase-9 and tenascin expression in primary bronchial fibroblasts. J Immunol (2004) 0.89
Pinning down signaling in the immune system: the role of the peptidyl-prolyl isomerase Pin1 in immune cell function. Crit Rev Immunol (2008) 0.89
The significance of Pin1 in the development of Alzheimer's disease. J Alzheimers Dis (2007) 0.88
MPEP reduces seizure severity in Fmr-1 KO mice over expressing human Abeta. Int J Clin Exp Pathol (2009) 0.87
Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells. J Neurochem (2009) 0.87
Thymic stromal lymphopoietin (TSLP) as a bridge between infection and atopy. Int J Clin Exp Pathol (2008) 0.85
Pin1 protein regulates Smad protein signaling and pulmonary fibrosis. J Biol Chem (2012) 0.85
Antisense targeting of TGF-beta1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells. Exp Cell Res (2007) 0.84
Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils. J Immunol (2013) 0.84
The Pin 1 inhibitor juglone attenuates kidney fibrogenesis via Pin 1-independent mechanisms in the unilateral ureteral occlusion model. Fibrogenesis Tissue Repair (2010) 0.83
Anti-Abeta: The good, the bad, and the unforeseen. J Neurosci Res (2004) 0.83
Soy-based diet exacerbates seizures in mouse models of neurological disease. J Alzheimers Dis (2013) 0.83
Pin1 null mice exhibit low bone mass and attenuation of BMP signaling. PLoS One (2013) 0.82
Serum and low-density lipoprotein enhance interleukin-8 secretion by airway epithelial cells. Am J Respir Cell Mol Biol (2003) 0.82
N-acetylcysteine prevents 4-hydroxynonenal- and amyloid-beta-induced modification and inactivation of neprilysin in SH-SY5Y cells. J Alzheimers Dis (2010) 0.81
Effects of 4-hydroxy-nonenal and Amyloid-beta on expression and activity of endothelin converting enzyme and insulin degrading enzyme in SH-SY5Y cells. J Alzheimers Dis (2009) 0.81
The regulation of AβPP expression by RNA-binding proteins. Ageing Res Rev (2012) 0.81
GM-CSF regulation in eosinophils. Arch Immunol Ther Exp (Warsz) (2002) 0.81
Dendritic cell-based immunotherapy for cancer and relevant challenges for transfusion medicine. Transfus Med Rev (2004) 0.80
Effect of Anticoagulants on Amyloid β-Protein Precursor and Amyloid Beta Levels in Plasma. J Alzheimers Dis Parkinsonism (2011) 0.80
Human airway eosinophils exhibit preferential reduction in STAT signaling capacity and increased CISH expression. J Immunol (2013) 0.79
Rck/p54 interacts with APP mRNA as part of a multi-protein complex and enhances APP mRNA and protein expression in neuronal cell lines. Neurobiol Aging (2008) 0.79
HuR mRNA ligands expressed after seizure. J Neuropathol Exp Neurol (2005) 0.78
Fragile X mental retardation protein in plasticity and disease. J Neurosci Res (2002) 0.78
Circadian changes in granulocyte-macrophage colony-stimulating factor message in circulating eosinophils. Ann Allergy Asthma Immunol (2007) 0.77
Determinants of eosinophil survival and apoptotic cell death. Apoptosis (2015) 0.77
Thymic stromal lymphopoietin expression in allergic pulmonary inflammation is Pin1-dependent. J Allergy Clin Immunol (2008) 0.77
Preparation of synaptoneurosomes from mouse cortex using a discontinuous percoll-sucrose density gradient. J Vis Exp (2011) 0.77
Interleukin-33: a potential link between rhinovirus infections and asthma exacerbation. Am J Respir Crit Care Med (2014) 0.75
Transforming Growth Factor-β1 Antagonizes Interleukin-5 Pro-Survival Signaling by Activating Calpain-1 in Primary Human Eosinophils. J Clin Cell Immunol (2011) 0.75
Plasma exchange after initial intravenous immunoglobulin treatment in Guillain-Barré syndrome: critical reassessment of effectiveness and cost-efficiency. J Clin Neuromuscul Dis (2010) 0.75