Published in Am J Respir Cell Mol Biol on November 20, 2003
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J Clin Invest (2008) 1.28
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Cross-talk between ICAM-1 and granulocyte-macrophage colony-stimulating factor receptor signaling modulates eosinophil survival and activation. J Immunol (2008) 1.11
Up-regulation and activation of eosinophil integrins in blood and airway after segmental lung antigen challenge. J Immunol (2008) 1.05
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Activation of beta1 integrins on blood eosinophils by P-selectin. Am J Respir Cell Mol Biol (2011) 0.92
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Identification of genes expressed by human airway eosinophils after an in vivo allergen challenge. PLoS One (2013) 0.90
Human eosinophils express RAGE, produce RAGE ligands, exhibit PKC-delta phosphorylation and enhanced viability in response to the RAGE ligand, S100B. Int Immunol (2011) 0.87
IL-5 induces suspended eosinophils to undergo unique global reorganization associated with priming. Am J Respir Cell Mol Biol (2014) 0.86
Potential contribution of IL-7 to allergen-induced eosinophilic airway inflammation in asthma. J Immunol (2009) 0.85
Opposing regulation of PROX1 by interleukin-3 receptor and NOTCH directs differential host cell fate reprogramming by Kaposi sarcoma herpes virus. PLoS Pathog (2012) 0.80
Cholesterol selectively regulates IL-5 induced mitogen activated protein kinase signaling in human eosinophils. PLoS One (2014) 0.80
Human airway eosinophils exhibit preferential reduction in STAT signaling capacity and increased CISH expression. J Immunol (2013) 0.79
Transforming Growth Factor-β1 Antagonizes Interleukin-5 Pro-Survival Signaling by Activating Calpain-1 in Primary Human Eosinophils. J Clin Cell Immunol (2011) 0.75
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An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med (2009) 9.38
Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL study. Am J Respir Crit Care Med (2004) 8.39
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med (2009) 7.17
Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol (2007) 6.33
Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial. Lancet (2003) 5.10
Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial. Lancet (2008) 4.06
Epithelial contact guidance on well-defined micro- and nanostructured substrates. J Cell Sci (2003) 3.79
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma. J Allergy Clin Immunol (2010) 3.12
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The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95. Proc Natl Acad Sci U S A (2003) 2.82
Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med (2004) 2.81
FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol (2007) 2.75
School examinations enhance airway inflammation to antigen challenge. Am J Respir Crit Care Med (2002) 2.41
Quantitative and qualitative analysis of rhinovirus infection in bronchial tissues. Am J Respir Crit Care Med (2004) 2.10
Severe asthma: lessons from the Severe Asthma Research Program. J Allergy Clin Immunol (2007) 2.10
Attitudes and actions of asthma patients on regular maintenance therapy: the INSPIRE study. BMC Pulm Med (2006) 2.08
Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study. Blood (2008) 2.00
Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis. J Allergy Clin Immunol (2005) 1.99
The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils. Nat Immunol (2005) 1.99
Once-daily fluticasone furoate is efficacious in patients with symptomatic asthma on low-dose inhaled corticosteroids. Ann Allergy Asthma Immunol (2012) 1.97
Severe asthma in adults: what are the important questions? J Allergy Clin Immunol (2007) 1.85
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med (2012) 1.85
Effects of early intervention with inhaled budesonide on lung function in newly diagnosed asthma. Chest (2006) 1.85
Asthma: clinical expression and molecular mechanisms. J Allergy Clin Immunol (2010) 1.84
Severe asthma: lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program. Am J Respir Crit Care Med (2011) 1.76
Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma. Am J Respir Crit Care Med (2005) 1.72
Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways. Am J Respir Crit Care Med (2014) 1.69
The role of rhinovirus in asthma exacerbations. J Allergy Clin Immunol (2005) 1.68
The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-alpha-induced priming of the NADPH oxidase in human neutrophils. Blood (2010) 1.68
Endotoxin-induced structural transformations in liquid crystalline droplets. Science (2011) 1.65
Obesity and asthma: an association modified by age of asthma onset. J Allergy Clin Immunol (2011) 1.64
Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program. Am J Respir Crit Care Med (2010) 1.62
The biofilm life cycle and virulence of Pseudomonas aeruginosa are dependent on a filamentous prophage. ISME J (2008) 1.58
A critical role for Pin1 in allergic pulmonary eosinophilia in rats. J Allergy Clin Immunol (2007) 1.58
Importance of hedgehog interacting protein and other lung function genes in asthma. J Allergy Clin Immunol (2011) 1.58
Similar frequency of rhinovirus-infectible cells in upper and lower airway epithelium. J Infect Dis (2002) 1.58
IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression. Am J Respir Crit Care Med (2006) 1.57
Rhinovirus-induced interferon-gamma and airway responsiveness in asthma. Am J Respir Crit Care Med (2003) 1.57
Dose effect of once-daily fluticasone furoate in persistent asthma: a randomized trial. Respir Med (2012) 1.57
Early intervention of recent onset mild persistent asthma in children aged under 11 yrs: the Steroid Treatment As Regular Therapy in early asthma (START) trial. Pediatr Allergy Immunol (2006) 1.54
The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study population. BMC Pulm Med (2009) 1.53
Neural circuitry underlying the interaction between emotion and asthma symptom exacerbation. Proc Natl Acad Sci U S A (2005) 1.53
Enhanced generation of helper T type 1 and 2 chemokines in allergen-induced asthma. Am J Respir Crit Care Med (2004) 1.53
Determinants of response to fluticasone propionate and salmeterol/fluticasone propionate combination in the Gaining Optimal Asthma controL study. J Allergy Clin Immunol (2007) 1.53
The effect of environmental factors on the response of human corneal epithelial cells to nanoscale substrate topography. Biomaterials (2006) 1.50
Severe exacerbations and decline in lung function in asthma. Am J Respir Crit Care Med (2008) 1.49
Airway lipoxin A4 generation and lipoxin A4 receptor expression are decreased in severe asthma. Am J Respir Crit Care Med (2008) 1.45
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia. J Allergy Clin Immunol (2013) 1.42
Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage-derived cytokines. J Allergy Clin Immunol (2008) 1.42
The nucleotide receptor P2X7 mediates actin reorganization and membrane blebbing in RAW 264.7 macrophages via p38 MAP kinase and Rho. J Leukoc Biol (2004) 1.37
24-h duration of the novel LABA vilanterol trifenatate in asthma patients treated with inhaled corticosteroids. Eur Respir J (2012) 1.36
beta-Amyloid degradation and Alzheimer's disease. J Biomed Biotechnol (2006) 1.35
Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol (2007) 1.30
The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation. Nat Immunol (2009) 1.29
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis. J Clin Invest (2008) 1.28
Similar colds in subjects with allergic asthma and nonatopic subjects after inoculation with rhinovirus-16. J Allergy Clin Immunol (2009) 1.28
Decreased expression of membrane IL-5 receptor alpha on human eosinophils: II. IL-5 down-modulates its receptor via a proteinase-mediated process. J Immunol (2002) 1.28
Human rhinovirus induces robust IP-10 release by monocytic cells, which is independent of viral replication but linked to type I interferon receptor ligation and STAT1 activation. J Leukoc Biol (2006) 1.28
IL-5 and granulocyte-macrophage colony-stimulating factor activate STAT3 and STAT5 and promote Pim-1 and cyclin D3 protein expression in human eosinophils. J Immunol (2004) 1.27
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Predicting intermediate phenotypes in asthma using bronchoalveolar lavage-derived cytokines. Clin Transl Sci (2010) 1.25
Age-related changes in eosinophil function in human subjects. Chest (2008) 1.22
Relationship of viral infections to wheezing illnesses and asthma. Nat Rev Immunol (2002) 1.21
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Once-daily fluticasone furoate alone or combined with vilanterol in persistent asthma. Eur Respir J (2013) 1.20
Differential transcriptomic responses of Biomphalaria glabrata (Gastropoda, Mollusca) to bacteria and metazoan parasites, Schistosoma mansoni and Echinostoma paraensei (Digenea, Platyhelminthes). Mol Immunol (2009) 1.19
The presence of rhinovirus in lower airways of patients with bronchial asthma. Am J Respir Crit Care Med (2008) 1.17
Increased thrombin activity after allergen challenge: a potential link to airway remodeling? Am J Respir Crit Care Med (2003) 1.16
Reversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO mice. PLoS One (2011) 1.15
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol (2013) 1.15
Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med (2013) 1.15
Evidence for nucleotide receptor modulation of cross talk between MAP kinase and NF-kappa B signaling pathways in murine RAW 264.7 macrophages. Am J Physiol Cell Physiol (2003) 1.15
Host immune responses to rhinovirus: mechanisms in asthma. J Allergy Clin Immunol (2008) 1.14
The relationship of rhinovirus-associated asthma hospitalizations with inhaled corticosteroids and smoking. J Infect Dis (2006) 1.13
Double-stranded RNA induces the synthesis of specific chemokines by bronchial epithelial cells. Am J Respir Cell Mol Biol (2002) 1.13
The role of p38 MAPK in rhinovirus-induced monocyte chemoattractant protein-1 production by monocytic-lineage cells. J Immunol (2005) 1.13
Workshop report from the National Institutes of Health Taskforce on the Research Needs of Eosinophil-Associated Diseases (TREAD). J Allergy Clin Immunol (2012) 1.12
How cytokines co-occur across asthma patients: from bipartite network analysis to a molecular-based classification. J Biomed Inform (2011) 1.12
Development and validation of the Composite Asthma Severity Index--an outcome measure for use in children and adolescents. J Allergy Clin Immunol (2012) 1.12
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. J Allergy Clin Immunol (2012) 1.11
Interferon-gamma enhances rhinovirus-induced RANTES secretion by airway epithelial cells. Am J Respir Cell Mol Biol (2002) 1.11
Detection of human P2X7 nucleotide receptor polymorphisms by a novel monocyte pore assay predictive of alterations in lipopolysaccharide-induced cytokine production. J Immunol (2005) 1.10
Mutation of a dibasic amino acid motif within the C terminus of the P2X7 nucleotide receptor results in trafficking defects and impaired function. J Immunol (2003) 1.10