Published in Mamm Genome on November 11, 2005
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A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nat Genet (2006) 3.35
Mutations in Col4a1 cause perinatal cerebral hemorrhage and porencephaly. Science (2005) 2.92
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An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Mol Cell (2013) 2.23
Positional cloning and characterization of mouse mei8, a disrupted allelle of the meiotic cohesin Rec8. Genesis (2004) 1.96
The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. EMBO J (2005) 1.76
Phenotype-based identification of mouse chromosome instability mutants. Genetics (2003) 1.74
The mouse genomic instability mutation chaos1 is an allele of Polq that exhibits genetic interaction with Atm. Mol Cell Biol (2004) 1.68
Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis. PLoS Genet (2007) 1.68
Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase. Genes Dev (2004) 1.64
Spata22, a novel vertebrate-specific gene, is required for meiotic progress in mouse germ cells. Biol Reprod (2012) 1.63
Tissue-specific functional networks for prioritizing phenotype and disease genes. PLoS Comput Biol (2012) 1.54
MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans. J Clin Invest (2012) 1.39
Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations. Genome Res (2005) 1.30
Positional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in mice. Proc Natl Acad Sci U S A (2003) 1.27
Mutation in mouse hei10, an e3 ubiquitin ligase, disrupts meiotic crossing over. PLoS Genet (2007) 1.25
The mouse meiotic mutation mei1 disrupts chromosome synapsis with sexually dimorphic consequences for meiotic progression. Dev Biol (2002) 1.24
Reversal of female infertility by Chk2 ablation reveals the oocyte DNA damage checkpoint pathway. Science (2014) 1.21
Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress. PLoS Genet (2010) 1.20
A dominant, recombination-defective allele of Dmc1 causing male-specific sterility. PLoS Biol (2007) 1.19
Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality. J Biol Chem (2010) 1.14
Minichromosome maintenance helicase paralog MCM9 is dispensible for DNA replication but functions in germ-line stem cells and tumor suppression. Proc Natl Acad Sci U S A (2011) 1.12
The dual bromodomain and WD repeat-containing mouse protein BRWD1 is required for normal spermiogenesis and the oocyte-embryo transition. Dev Biol (2008) 1.12
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Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver. Genetics (2012) 1.04
Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS Genet (2012) 1.02
Mouse H6 Homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass. BMC Dev Biol (2009) 1.02
A-MYB (MYBL1) transcription factor is a master regulator of male meiosis. Development (2011) 1.01
Female mice lacking estrogen receptor-alpha in osteoblasts have compromised bone mass and strength. J Bone Miner Res (2014) 1.00
Mei1 is epistatic to Dmc1 during mouse meiosis. Chromosoma (2005) 1.00
Phosphorylation of chromosome core components may serve as axis marks for the status of chromosomal events during mammalian meiosis. PLoS Genet (2012) 0.99
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Genetic evidence that synaptonemal complex axial elements govern recombination pathway choice in mice. Genetics (2011) 0.99
The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination. Mol Cell Biol (2013) 0.98
Aneuploidy and improved growth are coincident but not causal in a yeast cancer model. PLoS Biol (2009) 0.97
High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5. BMC Genet (2010) 0.95
Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations. Genetics (2006) 0.95
Genetic screen for chromosome instability in mice: Mcm4 and breast cancer. Cell Cycle (2007) 0.94
Overlapping deletions spanning the proximal two-thirds of the mouse t complex. Mamm Genome (2003) 0.94
Meiosis arrest female 1 (MARF1) has nuage-like function in mammalian oocytes. Proc Natl Acad Sci U S A (2012) 0.91
Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase. Genes (Basel) (2010) 0.91
MARF1 regulates essential oogenic processes in mice. Science (2012) 0.91
PDCD2 is essential for inner cell mass development and embryonic stem cell maintenance. Dev Biol (2010) 0.89
SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells. BMC Dev Biol (2010) 0.88
Post-transcriptional homeostasis and regulation of MCM2-7 in mammalian cells. Nucleic Acids Res (2012) 0.86
The mouse gcd2 mutation causes primordial germ cell depletion. Mech Dev (2006) 0.86
Different regulatory systems operate in the midpiece and principal piece of the mammalian sperm flagellum. Soc Reprod Fertil Suppl (2007) 0.86
An allelic series uncovers novel roles of the BRCT domain-containing protein PTIP in mouse embryonic vascular development. Mol Cell Biol (2008) 0.86
Functional annotation of mouse mutations in embryonic stem cells by use of expression profiling. Mamm Genome (2004) 0.84
A haplolethal locus uncovered by deletions in the mouse T complex. Genetics (2002) 0.83
Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitro. Regen Med (2014) 0.83
A reduction of licensed origins reveals strain-specific replication dynamics in mice. Mamm Genome (2011) 0.83
Using genetic networks and homology to understand the evolution of phenotypic traits. Curr Genomics (2012) 0.82
An allele separating skeletal patterning and spermatogonial renewal functions of PLZF. BMC Dev Biol (2010) 0.82
AKAP9 is essential for spermatogenesis and sertoli cell maturation in mice. Genetics (2013) 0.81
Development and use of DNA archives at veterinary teaching hospitals to investigate the genetic basis of disease in dogs. J Am Vet Med Assoc (2009) 0.81
The full-length isoform of the mouse pleckstrin homology domain-interacting protein (PHIP) is required for postnatal growth. FEBS Lett (2010) 0.80
Genetic background affects induced pluripotent stem cell generation. Stem Cell Res Ther (2012) 0.80
Overlapping deletions define novel embryonic lethal loci in the mouse t complex. Genesis (2003) 0.78
IQ motif-containing G (Iqcg) is required for mouse spermiogenesis. G3 (Bethesda) (2014) 0.78
Genomewide two-generation screens for recessive mutations by ES cell mutagenesis. Mamm Genome (2004) 0.78
Identification of a cryptic lethal mutation in the mouse t(w73) haplotype. Genet Res (2004) 0.76
Applying "Gold Standards" to In-Vitro-Derived Germ Cells. Cell (2014) 0.75