Published in Biochem Biophys Res Commun on November 08, 2005
Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1. Nature (2008) 3.68
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2. J Neurosci (2009) 1.59
Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis. PLoS Genet (2010) 1.42
dAtaxin-2 mediates expanded Ataxin-1-induced neurodegeneration in a Drosophila model of SCA1. PLoS Genet (2007) 1.38
Protein aggregation in amyotrophic lateral sclerosis. Acta Neuropathol (2013) 1.32
Deranged calcium signaling in Purkinje cells and pathogenesis in spinocerebellar ataxia 2 (SCA2) and other ataxias. Cerebellum (2012) 1.12
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice. Nature (2017) 1.11
Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2. Hum Mol Genet (2012) 1.05
Role of inositol 1,4,5-trisphosphate receptors in pathogenesis of Huntington's disease and spinocerebellar ataxias. Neurochem Res (2011) 1.04
Candidate genes for plasma triglyceride, FFA, and glucose revealed from an intercross between inbred mouse strains NZB/B1NJ and NZW/LacJ. J Lipid Res (2008) 0.97
Generation of human-induced pluripotent stem cells to model spinocerebellar ataxia type 2 in vitro. J Mol Neurosci (2012) 0.96
12q24 locus association with type 1 diabetes: SH2B3 or ATXN2? World J Diabetes (2014) 0.95
Evaluation of A2BP1 as an obesity gene. Diabetes (2010) 0.91
Macromolecular transport between the nucleus and the cytoplasm: Advances in mechanism and emerging links to disease. Biochim Biophys Acta (2014) 0.89
Dissociated fear and spatial learning in mice with deficiency of ataxin-2. PLoS One (2009) 0.88
Spinocerebellar ataxia type 2 (SCA2) in an Egyptian family presenting with polyphagia and marked CAG expansion in infancy. J Neurol (2008) 0.87
Ataxin-2 modulates the levels of Grb2 and SRC but not ras signaling. J Mol Neurosci (2013) 0.84
Genetically engineered mouse models of the trinucleotide-repeat spinocerebellar ataxias. Brain Res Bull (2011) 0.84
ETS1 regulates the expression of ATXN2. Hum Mol Genet (2012) 0.84
Unexpanded and intermediate CAG polymorphisms at the SCA2 locus (ATXN2) in the Cuban population: evidence about the origin of expanded SCA2 alleles. Eur J Hum Genet (2011) 0.83
Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7. Mol Ther (2014) 0.83
Therapeutic prospects for spinocerebellar ataxia type 2 and 3. Drugs Future (2009) 0.82
Recent advances in RNA interference therapeutics for CNS diseases. Neurotherapeutics (2013) 0.81
Genetic variance in the spinocerebellar ataxia type 2 (ATXN2) gene in children with severe early onset obesity. PLoS One (2009) 0.81
Ataxin-2 (Atxn2)-Knock-Out Mice Show Branched Chain Amino Acids and Fatty Acids Pathway Alterations. Mol Cell Proteomics (2016) 0.81
Genetic ablation of ataxin-2 increases several global translation factors in their transcript abundance but decreases translation rate. Neurogenetics (2015) 0.80
Ataxin-2 regulates RGS8 translation in a new BAC-SCA2 transgenic mouse model. PLoS Genet (2015) 0.80
Ataxin-2: From RNA Control to Human Health and Disease. Genes (Basel) (2017) 0.76
Degenerative ataxias, from genes to therapies: The 2015 Cotzias Lecture. Neurology (2016) 0.75
Cell size and fat content of dietary-restricted Caenorhabditis elegans are regulated by ATX-2, an mTOR repressor. Proc Natl Acad Sci U S A (2016) 0.75
Inositol 1,4,5-tripshosphate receptor, calcium signaling, and polyglutamine expansion disorders. Curr Top Membr (2010) 0.75
Motor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive Review. Front Neurosci (2016) 0.75
Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation. Biochim Biophys Acta (2016) 0.75
Heart regeneration in zebrafish. Science (2002) 10.45
Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism. Cell (2004) 7.45
Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia. Science (2002) 4.40
Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations. Proc Natl Acad Sci U S A (2005) 4.14
Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat Med (2007) 3.98
p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. Genes Dev (2005) 3.88
Spectrum and prevalence of cardiac sodium channel variants among black, white, Asian, and Hispanic individuals: implications for arrhythmogenic susceptibility and Brugada/long QT syndrome genetic testing. Heart Rhythm (2004) 3.15
Gene expression analysis of zebrafish heart regeneration. PLoS Biol (2006) 3.00
Tales of regeneration in zebrafish. Dev Dyn (2003) 2.63
A critical role for elastin signaling in vascular morphogenesis and disease. Development (2003) 2.47
fgf20 is essential for initiating zebrafish fin regeneration. Science (2005) 2.43
Vesicular glutamate transporter 3 is required for synaptic transmission in zebrafish hair cells. J Neurosci (2008) 2.36
FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction. Proc Natl Acad Sci U S A (2006) 2.30
Compound mutations: a common cause of severe long-QT syndrome. Circulation (2004) 2.29
Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel. Circulation (2002) 2.20
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF. Mol Cell (2004) 2.19
Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes. Nat Genet (2006) 2.09
Chemical modulation of receptor signaling inhibits regenerative angiogenesis in adult zebrafish. Nat Chem Biol (2006) 2.08
Mps1 defines a proximal blastemal proliferative compartment essential for zebrafish fin regeneration. Development (2002) 2.05
A cardiac arrhythmia syndrome caused by loss of ankyrin-B function. Proc Natl Acad Sci U S A (2004) 1.98
Metavinculin mutations alter actin interaction in dilated cardiomyopathy. Circulation (2002) 1.95
GTF2I hemizygosity implicated in mental retardation in Williams syndrome: genotype-phenotype analysis of five families with deletions in the Williams syndrome region. Am J Med Genet A (2003) 1.94
Location of mutation in the KCNQ1 and phenotypic presentation of long QT syndrome. J Cardiovasc Electrophysiol (2003) 1.91
Shared predispositions of parkinsonism and cancer: a population-based pedigree-linked study. Arch Neurol (2012) 1.87
Anillin localization defect in cardiomyocyte binucleation. J Mol Cell Cardiol (2006) 1.78
A proliferation gradient between proximal and msxb-expressing distal blastema directs zebrafish fin regeneration. Development (2002) 1.76
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 2. J Neurosci (2009) 1.59
Normal newt limb regeneration requires matrix metalloproteinase function. Dev Biol (2005) 1.59
Familial clustering of ALS in a population-based resource. Neurology (2013) 1.55
The GSK-3 inhibitor BIO promotes proliferation in mammalian cardiomyocytes. Chem Biol (2006) 1.52
CACNA1H mutations in autism spectrum disorders. J Biol Chem (2006) 1.35
Activin-betaA signaling is required for zebrafish fin regeneration. Curr Biol (2007) 1.31
Transcriptional profiling of caudal fin regeneration in zebrafish. ScientificWorldJournal (2006) 1.30
Late-onset Friedreich ataxia: phenotypic analysis, magnetic resonance imaging findings, and review of the literature. Arch Neurol (2005) 1.20
Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study. Orphanet J Rare Dis (2013) 1.15
Positional cloning of a temperature-sensitive mutant emmental reveals a role for sly1 during cell proliferation in zebrafish fin regeneration. Dev Biol (2003) 1.09
Heat-shock protein 60 is required for blastema formation and maintenance during regeneration. Proc Natl Acad Sci U S A (2005) 1.07
Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1. Genes Dev (2004) 1.03
Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling. Hum Mol Genet (2002) 0.97
An intronic mutation causes long QT syndrome. J Am Coll Cardiol (2004) 0.97
Quantification of vestibular-induced eye movements in zebrafish larvae. BMC Neurosci (2010) 0.96
Impaired interaction between the slide helix and the C-terminus of Kir2.1: a novel mechanism of Andersen syndrome. Cardiovasc Res (2007) 0.96
Tissue inhibitor of metalloproteinase 1 regulates matrix metalloproteinase activity during newt limb regeneration. Dev Dyn (2006) 0.94
Parkin is an E3 ubiquitin-ligase for normal and mutant ataxin-2 and prevents ataxin-2-induced cell death. Exp Neurol (2006) 0.93
HRS inhibits EGF receptor signaling in the RT4 rat schwannoma cell line. Biochem Biophys Res Commun (2005) 0.88
Phenotypic variability associated with Arg26Gln mutation in caveolin3. Muscle Nerve (2004) 0.86
Mesial temporal lobe epilepsy in a patient with spinocerebellar ataxia type 13 (SCA13). Int J Neurosci (2013) 0.86
ETS1 regulates the expression of ATXN2. Hum Mol Genet (2012) 0.84
Mitochondrial complex I gene variant associated with early age at onset in spinocerebellar ataxia type 2. Arch Neurol (2007) 0.81
Clinical evaluation of eye movements in spinocerebellar ataxias: a prospective multicenter study. J Neuroophthalmol (2015) 0.80
Coenzyme Q10 and spinocerebellar ataxias. Mov Disord (2014) 0.79
Effects of Nf2 missense mutations on schwannomin interactions. Biochem Biophys Res Commun (2002) 0.79
Bethlem myopathy in a black creole pedigree. J Clin Neuromuscul Dis (2002) 0.79
Genetic heterogeneity of stably transfected cell lines revealed by expression profiling with oligonucleotide microarrays. J Cell Biochem (2003) 0.78
Ataxin-2 mediated cell death is dependent on domains downstream of the polyQ repeat. Exp Neurol (2007) 0.78
Dystonia (DYT) genetic loci. Eur J Paediatr Neurol (2005) 0.77
Juvenile parkinsonism. Eur J Paediatr Neurol (2008) 0.76
Repolarization matters: mutations in the Kv4.3 potassium channel cause SCA19/22. Ann Neurol (2012) 0.75
Segmental unilateral lentiginosis in generalized neurofibromatosis type 1. Arch Neurol (2002) 0.75