PubRank

Alan N Schechter

Author PubWeight™ 103.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Pulmonary hypertension as a risk factor for death in patients with sickle cell disease. N Engl J Med 2004 10.51
2 Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nat Med 2003 8.95
3 Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med 2002 7.59
4 Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control. J Clin Invest 2005 3.08
5 The emerging biology of the nitrite anion. Nat Chem Biol 2005 2.88
6 Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation. Blood 2005 2.76
7 Hemolysis-associated endothelial dysfunction mediated by accelerated NO inactivation by decompartmentalized oxyhemoglobin. J Clin Invest 2005 2.75
8 Nitrite infusion in humans and nonhuman primates: endocrine effects, pharmacokinetics, and tolerance formation. Circulation 2007 2.46
9 Hemolysis in sickle cell mice causes pulmonary hypertension due to global impairment in nitric oxide bioavailability. Blood 2007 2.30
10 NO contest: nitrite versus S-nitroso-hemoglobin. Circ Res 2004 2.21
11 Inhaled nebulized nitrite is a hypoxia-sensitive NO-dependent selective pulmonary vasodilator. Nat Med 2004 2.09
12 Erythrocytes are the major intravascular storage sites of nitrite in human blood. Blood 2005 2.08
13 Hydroxyurea induces fetal hemoglobin by the nitric oxide-dependent activation of soluble guanylyl cyclase. J Clin Invest 2003 2.00
14 Divergent nitric oxide bioavailability in men and women with sickle cell disease. Circulation 2003 1.98
15 Randomization in clinical trials of titrated therapies: unintended consequences of using fixed treatment protocols. Crit Care Med 2007 1.88
16 Plasma nitrite concentrations reflect the degree of endothelial dysfunction in humans. Free Radic Biol Med 2005 1.85
17 Unraveling the reactions of nitric oxide, nitrite, and hemoglobin in physiology and therapeutics. Arterioscler Thromb Vasc Biol 2006 1.79
18 Red blood cell magnetophoresis. Biophys J 2003 1.78
19 S-Nitrosohemoglobin is unstable in the reductive erythrocyte environment and lacks O2/NO-linked allosteric function. J Biol Chem 2002 1.62
20 Nitric oxide's reactions with hemoglobin: a view through the SNO-storm. Nat Med 2003 1.61
21 Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease. Br J Haematol 2002 1.52
22 Erythropoietin and hypoxia stimulate erythropoietin receptor and nitric oxide production by endothelial cells. Blood 2004 1.43
23 The measurement of blood and plasma nitrite by chemiluminescence: pitfalls and solutions. Free Radic Biol Med 2006 1.38
24 Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells. Blood 2007 1.27
25 Platelet inhibition by nitrite is dependent on erythrocytes and deoxygenation. PLoS One 2012 1.23
26 Exogenous reference RNA for normalization of real-time quantitative PCR. Biotechniques 2003 1.19
27 The reaction between nitrite and oxyhemoglobin: a mechanistic study. J Biol Chem 2008 1.14
28 Increasing hemoglobin oxygen saturation levels in sickle trait donor whole blood prevents hemoglobin S polymerization and allows effective white blood cell reduction by filtration. Transfusion 2004 1.12
29 Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells. Blood 2006 1.12
30 Emerging role of nitrite in human biology. Blood Cells Mol Dis 2004 1.07
31 Funding priorities for medical research. JAMA 2002 1.06
32 Nitric oxide from nitrite reduction by hemoglobin in the plasma and erythrocytes. Nitric Oxide 2007 1.03
33 Fetal hemoglobin silencing in humans. Blood 2006 1.03
34 Translational medicine--doing it backwards. J Transl Med 2010 1.03
35 Dietary nitrite and nitrate: a review of potential mechanisms of cardiovascular benefits. Eur J Nutr 2011 1.03
36 Effect of blood nitrite and nitrate levels on murine platelet function. PLoS One 2013 1.00
37 NIH support for basic and clinical research: biomedical researcher angst in 2006. JAMA 2006 0.99
38 Effects of iron nitrosylation on sickle cell hemoglobin solubility. J Biol Chem 2002 0.98
39 Inorganic nitrate: a major player in the cardiovascular health benefits of vegetables? Nutr Rev 2012 0.98
40 Electron paramagnetic resonance analysis of nitrosylhemoglobin in humans during NO inhalation. J Biol Chem 2005 0.94
41 Erythropoietin and hypoxia increase erythropoietin receptor and nitric oxide levels in lung microvascular endothelial cells. Cytokine 2011 0.89
42 Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life. PLoS One 2013 0.88
43 Acute erythropoietin cardioprotection is mediated by endothelial response. Basic Res Cardiol 2011 0.88
44 Sickle Hb polymerization in RBC components from donors with sickle cell trait prevents effective WBC reduction by filtration. Transfusion 2002 0.88
45 Oxidation of iron-nitrosyl-hemoglobin by dehydroascorbic acid releases nitric oxide to form nitrite in human erythrocytes. Biochemistry 2008 0.86
46 Measurement of nitrite in blood samples using the ferricyanide-based hemoglobin oxidation assay. Methods Mol Biol 2011 0.84
47 Increasing oxygen tension improves filtration of sickle trait donor blood. Br J Haematol 2003 0.83
48 The reaction of cell-free oxyhemoglobin with nitrite under physiologically relevant conditions: Implications for nitrite-based therapies. Nitric Oxide 2008 0.83
49 Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity. Nitric Oxide 2007 0.82
50 Effects of nitric oxide on red blood cell development and phenotype. Curr Top Dev Biol 2008 0.82
51 Globin gene expression in correlation with G protein-related genes during erythroid differentiation. BMC Genomics 2013 0.80
52 The role of nitrite in neurovascular coupling. Brain Res 2011 0.80
53 Comments on 'vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway'. Br J Clin Pharmacol 2013 0.80
54 JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny. J Transl Med 2012 0.79
55 Identification and characterization of mechanistically distinct inducers of gamma-globin transcription. Biochem Pharmacol 2003 0.78
56 Effect of storage on levels of nitric oxide metabolites in platelet preparations. Transfusion 2012 0.77
57 Correction: Nitrate Reduction to Nitrite, Nitric Oxide and Ammonia by Gut Bacteria under Physiological Conditions. PLoS One 2015 0.76
58 How do red blood cells dilate blood vessels?--Reply. Circ Res 2004 0.75
59 Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production. Exp Hematol 2009 0.75
60 To publish or not to publish? J Lab Clin Med 2005 0.75
61 Introduction to the symposium on synthetic life. Perspect Biol Med 2012 0.75
62 In vivo reduction of cell-free methemoglobin to oxyhemoglobin results in vasoconstriction in canines. Transfusion 2013 0.75
63 In reply. Transfusion 2013 0.75
64 Linderstrom-Lang-Schellman's model for protein stabilization revisited. Curr Protein Pept Sci 2004 0.75
65 Introduction to the symposium on recurrent debates on the causal role of genes. Perspect Biol Med 2014 0.75
66 General Introduction. Perspect Biol Med 2015 0.75