John W Newman

Author PubWeight™ 78.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The human serum metabolome. PLoS One 2011 5.55
2 Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proc Natl Acad Sci U S A 2005 4.07
3 Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women. J Nutr 2009 3.32
4 Structural refinement of inhibitors of urea-based soluble epoxide hydrolases. Biochem Pharmacol 2002 2.86
5 An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension 2005 2.76
6 Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. J Am Soc Nephrol 2004 2.59
7 Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ Res 2006 2.33
8 Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PLoS One 2010 2.14
9 Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat Neurosci 2008 2.09
10 Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice. J Biol Chem 2006 1.95
11 Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways. J Lipid Res 2012 1.79
12 Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Hum Mol Genet 2006 1.74
13 Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation. J Lipid Res 2008 1.71
14 An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol 2005 1.59
15 Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters. J Lipid Res 2009 1.42
16 Increased expression of receptors for orexigenic factors in nodose ganglion of diet-induced obese rats. Am J Physiol Endocrinol Metab 2009 1.37
17 Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. Clin Sci (Lond) 2009 1.34
18 Increased blood pressure in mice lacking cytochrome P450 2J5. FASEB J 2008 1.30
19 Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase. Biochemistry 2005 1.21
20 Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery. Anal Bioanal Chem 2012 1.18
21 In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea. Drug Metab Dispos 2003 1.14
22 Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers. J Lipid Res 2012 1.12
23 imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel. Bioinformatics 2012 1.12
24 Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids. PLoS One 2012 1.09
25 Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. J Am Coll Nutr 2003 1.06
26 Peptidyl-urea based inhibitors of soluble epoxide hydrolases. Bioorg Med Chem Lett 2006 1.05
27 IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal. Circ Res 2012 1.04
28 Impact of circulating esterified eicosanoids and other oxylipins on endothelial function. Curr Atheroscler Rep 2009 1.03
29 Lipoprotein lipase releases esterified oxylipins from very low-density lipoproteins. Prostaglandins Leukot Essent Fatty Acids 2008 1.02
30 Genetic contribution of the leukotriene pathway to coronary artery disease. Hum Genet 2011 0.96
31 12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms. Atherosclerosis 2011 0.95
32 Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obes Res 2004 0.93
33 Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. Chem Res Toxicol 2008 0.93
34 Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study. BMC Med Genomics 2010 0.89
35 Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice. Am J Respir Cell Mol Biol 2014 0.89
36 Effect of industrially produced trans fat on markers of systemic inflammation: evidence from a randomized trial in women. J Lipid Res 2011 0.89
37 Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition. J Pharmacol Exp Ther 2005 0.89
38 Fatty acid composition of liver, adipose tissue, spleen, and heart of mice fed diets containing t10, c12-, and c9, t11-conjugated linoleic acid. Prostaglandins Leukot Essent Fatty Acids 2006 0.87
39 Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics 2007 0.86
40 Methylmalonic acid quantification in low serum volumes by UPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2011 0.85
41 Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research. J Nutr 2010 0.84
42 ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation. J Lipid Res 2011 0.83
43 Vitamin B-12 supplementation of rural Mexican women changes biochemical vitamin B-12 status indicators but does not affect hematology or a bone turnover marker. J Nutr 2012 0.83
44 Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets. J Lipid Res 2013 0.83
45 Arachidonate 5-lipoxygenase gene variants affect response to fish oil supplementation by healthy African Americans. J Nutr 2012 0.82
46 Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism. Toxicol Sci 2004 0.82
47 The effect of docosahexaenoic acid on t10, c12-conjugated linoleic acid-induced changes in fatty acid composition of mouse liver, adipose, and muscle. Metab Syndr Relat Disord 2012 0.81
48 Graded effects of proteinuria on HDL structure in nephrotic rats. J Am Soc Nephrol 2005 0.81
49 Congener-based Aroclor quantification and speciation techniques: a comparison of the strengths, weaknesses, and proper use of two alternative approaches. Environ Sci Technol 2003 0.80
50 Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol. BMC Cardiovasc Disord 2013 0.80
51 Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model. Int J Oncol 2011 0.80
52 Effects of dynamic exercise on plasma arachidonic acid epoxides and diols in human volunteers. Int J Sport Nutr Exerc Metab 2011 0.80
53 Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults. Nutrients 2013 0.79
54 Salt loading increases urinary excretion of linoleic acid diols and triols in healthy human subjects. Hypertension 2008 0.79
55 Daily consumption of orange-fleshed sweet potato for 60 days increased plasma β-carotene concentration but did not increase total body vitamin A pool size in Bangladeshi women. J Nutr 2012 0.78
56 Direct comparison of fatty acid ratios in single cellular lipid droplets as determined by comparative Raman spectroscopy and gas chromatography. Analyst 2013 0.78
57 Variation in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful? Nutr Metab (Lond) 2012 0.77
58 Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice. Int J Oncol 2012 0.77
59 Habitual diets rich in dark-green vegetables are associated with an increased response to ω-3 fatty acid supplementation in Americans of African ancestry. J Nutr 2013 0.76
60 Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model. Int J Oncol 2012 0.75
61 Effects of pyridine exposure upon structural lipid metabolism in Swiss Webster mice. Chem Res Toxicol 2008 0.75