Published in Prostaglandins Leukot Essent Fatty Acids on November 29, 2008
Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters. J Lipid Res (2009) 1.42
Fish oil -- how does it reduce plasma triglycerides? Biochim Biophys Acta (2011) 1.20
Lowering dietary linoleic acid reduces bioactive oxidized linoleic acid metabolites in humans. Prostaglandins Leukot Essent Fatty Acids (2012) 1.09
Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. Prostaglandins Leukot Essent Fatty Acids (2013) 0.98
Cytochrome P450 epoxygenase pathway of polyunsaturated fatty acid metabolism. Biochim Biophys Acta (2014) 0.91
Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA. Prostaglandins Other Lipid Mediat (2014) 0.90
Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins. Prostaglandins Other Lipid Mediat (2014) 0.85
Lipid profiling following intake of the omega 3 fatty acid DHA identifies the peroxidized metabolites F4-neuroprostanes as the best predictors of atherosclerosis prevention. PLoS One (2014) 0.84
Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study. J Lipid Res (2015) 0.83
Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids: Implications for idiopathic pain syndromes? Mol Pain (2016) 0.80
Aging, estrogen loss and epoxyeicosatrienoic acids (EETs). PLoS One (2013) 0.79
The Postprandial Effects of a Moderately High-Fat Meal on Lipid Profiles and Vascular Inflammation in Alzheimer's Disease Patients: A Pilot Study. J Gen Pract (Los Angel) (2015) 0.77
High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy. Circ Cardiovasc Genet (2014) 0.76
Effect of omega-3 fatty acid ethyl esters on the oxylipin composition of lipoproteins in hypertriglyceridemic, statin-treated subjects. PLoS One (2014) 0.76
EPA and/or DHA? A test question on the principles and opportunities in utilizing the therapeutic potential of omega-3 fatty acids. J Lipid Res (2016) 0.75
Omega-6 and omega-3 oxylipins are implicated in soybean oil-induced obesity in mice. Sci Rep (2017) 0.75
Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: An exploratory study. Psychiatry Res (2017) 0.75
Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proc Natl Acad Sci U S A (2005) 4.07
Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway. Circ Res (2004) 2.98
Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. Proc Natl Acad Sci U S A (1992) 2.51
The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS. J Lipid Res (2002) 2.32
Sequential flotation ultracentrifugation. Methods Enzymol (1986) 2.27
Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases. Am J Physiol Renal Physiol (2005) 2.10
Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors. Proc Natl Acad Sci U S A (2006) 2.07
Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. J Biol Chem (2005) 1.73
Lipid inflammatory mediators in diabetic vascular disease. Arterioscler Thromb Vasc Biol (2004) 1.61
Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques. J Clin Invest (1995) 1.47
Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease. Free Radic Biol Med (2006) 1.33
Interaction of prostaglandins with blood plasma proteins. Comparative binding of prostaglandins A 2 , F 2 and E 2 to human plasma proteins. Biochem J (1972) 1.32
Beyond vasodilatation: non-vasomotor roles of epoxyeicosatrienoic acids in the cardiovascular system. Trends Pharmacol Sci (2006) 1.28
Arachidonic acid epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma. Biochem Biophys Res Commun (1992) 1.21
Identification of 9-hydroxyoctadecadienoic acid and other oxidized free fatty acids as ligands of the G protein-coupled receptor G2A. J Biol Chem (2005) 1.15
High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha: a candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion. Circ Res (2006) 1.06
13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells. Biochem Pharmacol (2007) 1.06
Proteinuria increases oxylipid concentrations in VLDL and HDL but not LDL particles in the rat. J Lipid Res (2007) 1.06
5-oxo-6,8,11,14-eicosatetraenoic acid induces the infiltration of granulocytes into human skin. J Allergy Clin Immunol (2003) 0.99
5-oxo-ETE induces pulmonary eosinophilia in an integrin-dependent manner in Brown Norway rats. J Clin Invest (1998) 0.95
Interaction of prostaglandins with blood plasma proteins. I. Binding of prostaglandin E 2 to human plasma proteins and its effect on the physiological activity of prostaglandin E 2 in vitro and in vivo. Biochim Biophys Acta (1972) 0.93
Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL. J Lipid Res (1994) 0.93
Induction of interleukin 1 beta expression from human peripheral blood monocyte-derived macrophages by 9-hydroxyoctadecadienoic acid. J Biol Chem (1992) 0.93
Identification and analysis of products formed from phospholipids in the free radical oxidation of human low density lipoproteins. J Lipid Res (2004) 0.91
Measurement of products of docosahexaenoic acid peroxidation, neuroprostanes, and neurofurans. Methods Enzymol (2007) 0.91
Endothelial bound lipoprotein lipase (LpL) depletion in hypoalbuminemia results from decreased endothelial binding, not decreased secretion. Kidney Int (2006) 0.90
Lipolytic PPAR activation: new insights into the intersection of triglycerides and inflammation? Curr Opin Clin Nutr Metab Care (2004) 0.90
Hypoalbuminemia and proteinuria contribute separately to reduced lipoprotein catabolism in the nephrotic syndrome. Kidney Int (2001) 0.87
Insulin and glucose play a role in foam cell formation and function. Cardiovasc Diabetol (2006) 0.87
Novel site in lipoprotein lipase (LPL415;-438) essential for substrate interaction and dimer stability. J Lipid Res (2001) 0.85
Interactions of prostaglandin H2 and thromboxane A2 with human serum albumin. Eur J Biochem (1980) 0.82
Oxidation of glycerophospholipids from biological membranes by reactive oxygen species: liquid chromatographic-mass spectrometric analysis of eicosanoid products. J Chromatogr B Biomed Sci Appl (1999) 0.81
Disparate effects of 12-lipoxygenase and 12-hydroxyeicosatetraenoic acid in vascular endothelial and smooth muscle cells and in cardiomyocytes. Arch Physiol Biochem (2006) 0.80
Translocation of phospholipase A2 to membranes by oxidized LDL and hydroxyoctadecadienoic acid to contribute to cholesteryl ester formation. Biochim Biophys Acta (2004) 0.78
Increased clearance of low density lipoprotein precursors in patients with heterozygous familial defective apolipoprotein B-100: a stable isotope approach. J Lipid Res (1996) 0.77
The association between apolipoprotein A-I and prostacyclin binding in human serum. Prostaglandins (1989) 0.77
Interaction of prostaglandins with blood plasma proteins. 3. Rate of disappearance and metabolites formation after intravenous administration of free or albumin-bound prostaglandins F 2 and A 2 . Life Sci II (1972) 0.77
Perturbation of lipid metabolism by linoleic acid hydroperoxide in CaCo-2 cells. Biol Chem (2002) 0.76
The human serum metabolome. PLoS One (2011) 5.55
Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proc Natl Acad Sci U S A (2005) 4.07
Structural refinement of inhibitors of urea-based soluble epoxide hydrolases. Biochem Pharmacol (2002) 2.86
An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension (2005) 2.76
Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. J Am Soc Nephrol (2004) 2.59
Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ Res (2006) 2.33
Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PLoS One (2010) 2.14
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nat Neurosci (2008) 2.09
Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice. J Biol Chem (2006) 1.95
Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways. J Lipid Res (2012) 1.79
Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Hum Mol Genet (2006) 1.74
Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation. J Lipid Res (2008) 1.71
An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol (2005) 1.59
Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters. J Lipid Res (2009) 1.42
Increased expression of receptors for orexigenic factors in nodose ganglion of diet-induced obese rats. Am J Physiol Endocrinol Metab (2009) 1.37
Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats. Clin Sci (Lond) (2009) 1.34
Increased blood pressure in mice lacking cytochrome P450 2J5. FASEB J (2008) 1.30
Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase. Biochemistry (2005) 1.21
Quantitative profiling of oxylipins through comprehensive LC-MS/MS analysis: application in cardiac surgery. Anal Bioanal Chem (2012) 1.18
In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecyl-urea. Drug Metab Dispos (2003) 1.14
Basal omega-3 fatty acid status affects fatty acid and oxylipin responses to high-dose n3-HUFA in healthy volunteers. J Lipid Res (2012) 1.12
imDEV: a graphical user interface to R multivariate analysis tools in Microsoft Excel. Bioinformatics (2012) 1.12
Type 2 diabetes associated changes in the plasma non-esterified fatty acids, oxylipins and endocannabinoids. PLoS One (2012) 1.09
Involvement of CYP 2C9 in mediating the proinflammatory effects of linoleic acid in vascular endothelial cells. J Am Coll Nutr (2003) 1.06
Peptidyl-urea based inhibitors of soluble epoxide hydrolases. Bioorg Med Chem Lett (2006) 1.05
IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high-fat meal. Circ Res (2012) 1.04
Impact of circulating esterified eicosanoids and other oxylipins on endothelial function. Curr Atheroscler Rep (2009) 1.03
Genetic contribution of the leukotriene pathway to coronary artery disease. Hum Genet (2011) 0.96
12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms. Atherosclerosis (2011) 0.95
Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obes Res (2004) 0.93
Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. Chem Res Toxicol (2008) 0.93
Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study. BMC Med Genomics (2010) 0.89
Effect of industrially produced trans fat on markers of systemic inflammation: evidence from a randomized trial in women. J Lipid Res (2011) 0.89
Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice. Am J Respir Cell Mol Biol (2014) 0.89
Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition. J Pharmacol Exp Ther (2005) 0.89
Fatty acid composition of liver, adipose tissue, spleen, and heart of mice fed diets containing t10, c12-, and c9, t11-conjugated linoleic acid. Prostaglandins Leukot Essent Fatty Acids (2006) 0.87
Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics (2007) 0.86
Methylmalonic acid quantification in low serum volumes by UPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci (2011) 0.85
Web-enabled and improved software tools and data are needed to measure nutrient intakes and physical activity for personalized health research. J Nutr (2010) 0.84
Vitamin B-12 supplementation of rural Mexican women changes biochemical vitamin B-12 status indicators but does not affect hematology or a bone turnover marker. J Nutr (2012) 0.83
ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation. J Lipid Res (2011) 0.83
Plasma oxylipin profiling identifies polyunsaturated vicinal diols as responsive to arachidonic acid and docosahexaenoic acid intake in growing piglets. J Lipid Res (2013) 0.83
Arachidonate 5-lipoxygenase gene variants affect response to fish oil supplementation by healthy African Americans. J Nutr (2012) 0.82
Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism. Toxicol Sci (2004) 0.82
The effect of docosahexaenoic acid on t10, c12-conjugated linoleic acid-induced changes in fatty acid composition of mouse liver, adipose, and muscle. Metab Syndr Relat Disord (2012) 0.81
Graded effects of proteinuria on HDL structure in nephrotic rats. J Am Soc Nephrol (2005) 0.81
Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol. BMC Cardiovasc Disord (2013) 0.80
Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model. Int J Oncol (2011) 0.80
Congener-based Aroclor quantification and speciation techniques: a comparison of the strengths, weaknesses, and proper use of two alternative approaches. Environ Sci Technol (2003) 0.80
Effects of dynamic exercise on plasma arachidonic acid epoxides and diols in human volunteers. Int J Sport Nutr Exerc Metab (2011) 0.80
Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults. Nutrients (2013) 0.79
Salt loading increases urinary excretion of linoleic acid diols and triols in healthy human subjects. Hypertension (2008) 0.79
Direct comparison of fatty acid ratios in single cellular lipid droplets as determined by comparative Raman spectroscopy and gas chromatography. Analyst (2013) 0.78
Variation in metabolic responses to meal challenges differing in glycemic index in healthy women: Is it meaningful? Nutr Metab (Lond) (2012) 0.77
Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice. Int J Oncol (2012) 0.77
Habitual diets rich in dark-green vegetables are associated with an increased response to ω-3 fatty acid supplementation in Americans of African ancestry. J Nutr (2013) 0.76
Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model. Int J Oncol (2012) 0.75
Effects of pyridine exposure upon structural lipid metabolism in Swiss Webster mice. Chem Res Toxicol (2008) 0.75