Published in Nature on November 24, 2005
Enzymatic assembly of DNA molecules up to several hundred kilobases. Nat Methods (2009) 22.47
Engineering BioBrick vectors from BioBrick parts. J Biol Eng (2008) 5.98
Synthetic biology: new engineering rules for an emerging discipline. Mol Syst Biol (2006) 5.92
A synchronized quorum of genetic clocks. Nature (2010) 5.47
Genome engineering. Nat Biotechnol (2009) 4.60
Systems medicine: the future of medical genomics and healthcare. Genome Med (2009) 3.85
Programming gene expression with combinatorial promoters. Mol Syst Biol (2007) 3.29
Environmental signal integration by a modular AND gate. Mol Syst Biol (2007) 3.25
A synthetic genetic edge detection program. Cell (2009) 3.20
Modular cell biology: retroactivity and insulation. Mol Syst Biol (2008) 3.11
A synthetic Escherichia coli predator-prey ecosystem. Mol Syst Biol (2008) 2.92
A modular and extensible RNA-based gene-regulatory platform for engineering cellular function. Proc Natl Acad Sci U S A (2007) 2.91
Dispersing biofilms with engineered enzymatic bacteriophage. Proc Natl Acad Sci U S A (2007) 2.87
Synthetic biology: caught between property rights, the public domain, and the commons. PLoS Biol (2007) 2.80
Measuring the activity of BioBrick promoters using an in vivo reference standard. J Biol Eng (2009) 2.79
High-fidelity gene synthesis by retrieval of sequence-verified DNA identified using high-throughput pyrosequencing. Nat Biotechnol (2010) 2.68
Precise and reliable gene expression via standard transcription and translation initiation elements. Nat Methods (2013) 2.61
Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen. Mol Syst Biol (2011) 2.59
The role of social scientists in synthetic biology. Science & Society Series on Convergence Research. EMBO Rep (2009) 2.57
Using movies to analyse gene circuit dynamics in single cells. Nat Rev Microbiol (2009) 2.44
Combinatorial promoter design for engineering noisy gene expression. Proc Natl Acad Sci U S A (2007) 2.40
Targeted development of registries of biological parts. PLoS One (2008) 2.33
BglBricks: A flexible standard for biological part assembly. J Biol Eng (2010) 2.32
Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae. Nat Chem Biol (2008) 2.19
A sensing array of radically coupled genetic 'biopixels'. Nature (2011) 2.18
Quantitative estimation of activity and quality for collections of functional genetic elements. Nat Methods (2013) 2.03
Diffusion of synthetic biology: a challenge to biosafety. Syst Synth Biol (2008) 2.00
The economics of synthetic biology. Mol Syst Biol (2007) 1.99
Synthetic biology: promises and challenges. Mol Syst Biol (2007) 1.99
Genomic mining of prokaryotic repressors for orthogonal logic gates. Nat Chem Biol (2013) 1.98
RNA processing enables predictable programming of gene expression. Nat Biotechnol (2012) 1.92
Design and characterization of molecular tools for a Synthetic Biology approach towards developing cyanobacterial biotechnology. Nucleic Acids Res (2010) 1.88
Engineering biological systems with synthetic RNA molecules. Mol Cell (2011) 1.80
Principles of genetic circuit design. Nat Methods (2014) 1.79
Frameworks for programming biological function through RNA parts and devices. Chem Biol (2009) 1.74
Ribozyme-based insulator parts buffer synthetic circuits from genetic context. Nat Biotechnol (2012) 1.70
Synthetic biology: integrated gene circuits. Science (2011) 1.66
Rationally designed families of orthogonal RNA regulators of translation. Nat Chem Biol (2012) 1.66
Entrainment of a population of synthetic genetic oscillators. Science (2011) 1.66
Writing DNA with GenoCAD. Nucleic Acids Res (2009) 1.60
A synthetic time-delay circuit in mammalian cells and mice. Proc Natl Acad Sci U S A (2007) 1.59
Design, construction and characterization of a set of insulated bacterial promoters. Nucleic Acids Res (2010) 1.55
A load driver device for engineering modularity in biological networks. Nat Biotechnol (2014) 1.53
Synthetic organisms and living machines : Positioning the products of synthetic biology at the borderline between living and non-living matter. Syst Synth Biol (2009) 1.53
Composability of regulatory sequences controlling transcription and translation in Escherichia coli. Proc Natl Acad Sci U S A (2013) 1.53
Rational diversification of a promoter providing fine-tuned expression and orthogonal regulation for synthetic biology. PLoS One (2012) 1.52
Towards programming languages for genetic engineering of living cells. J R Soc Interface (2009) 1.51
Cell-free synthetic biology: thinking outside the cell. Metab Eng (2011) 1.49
Model-guided design of ligand-regulated RNAi for programmable control of gene expression. Mol Syst Biol (2008) 1.46
Synthesis of orthogonal transcription-translation networks. Proc Natl Acad Sci U S A (2009) 1.46
The Standard European Vector Architecture (SEVA): a coherent platform for the analysis and deployment of complex prokaryotic phenotypes. Nucleic Acids Res (2012) 1.42
Teaching synthetic biology, bioinformatics and engineering to undergraduates: the interdisciplinary Build-a-Genome course. Genetics (2008) 1.41
A comparative analysis of synthetic genetic oscillators. J R Soc Interface (2010) 1.41
Reproducibility of Fluorescent Expression from Engineered Biological Constructs in E. coli. PLoS One (2016) 1.41
Synthetic biology in mammalian cells: next generation research tools and therapeutics. Nat Rev Mol Cell Biol (2014) 1.41
Engineered Regulatory Systems Modulate Gene Expression of Human Commensals in the Gut. Cell (2017) 1.40
TinkerCell: modular CAD tool for synthetic biology. J Biol Eng (2009) 1.38
Designing and engineering evolutionary robust genetic circuits. J Biol Eng (2010) 1.37
Laying the foundations for a bio-economy. Syst Synth Biol (2008) 1.36
Fast, cheap and somewhat in control. Genome Biol (2006) 1.35
Synthetic biology: discovering new worlds and new words. EMBO Rep (2008) 1.35
Biology by design: reduction and synthesis of cellular components and behaviour. J R Soc Interface (2007) 1.33
The transcription factor titration effect dictates level of gene expression. Cell (2014) 1.30
High-yield hydrogen production from starch and water by a synthetic enzymatic pathway. PLoS One (2007) 1.29
Application of synthetic biology in cyanobacteria and algae. Front Microbiol (2012) 1.28
Synthetic translational regulation by an L7Ae-kink-turn RNP switch. Nat Chem Biol (2009) 1.28
Piecing together a puzzle. An exposition of synthetic biology. EMBO Rep (2009) 1.28
Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology. J Biomed Biotechnol (2010) 1.27
Molecular circuits for associative learning in single-celled organisms. J R Soc Interface (2008) 1.25
OptCircuit: an optimization based method for computational design of genetic circuits. BMC Syst Biol (2008) 1.24
Synthetic protocell biology: from reproduction to computation. Philos Trans R Soc Lond B Biol Sci (2007) 1.23
Quantitative dissection of the simple repression input-output function. Proc Natl Acad Sci U S A (2011) 1.23
Designing and encoding models for synthetic biology. J R Soc Interface (2009) 1.23
The Modular Organization of Protein Interactions in Escherichia coli. PLoS Comput Biol (2009) 1.20
Synthetic biology in society: learning from past experience? Syst Synth Biol (2009) 1.20
Small-scale copy number variation and large-scale changes in gene expression. Proc Natl Acad Sci U S A (2008) 1.20
Standard biological parts knowledgebase. PLoS One (2011) 1.19
Synthetic biology: ethical ramifications 2009. Syst Synth Biol (2009) 1.18
Tracing explosives in soil with transcriptional regulators of Pseudomonas putida evolved for responding to nitrotoluenes. Microb Biotechnol (2008) 1.17
Robust synchronization control scheme of a population of nonlinear stochastic synthetic genetic oscillators under intrinsic and extrinsic molecular noise via quorum sensing. BMC Syst Biol (2012) 1.17
A survey of enabling technologies in synthetic biology. J Biol Eng (2013) 1.14
Informing biological design by integration of systems and synthetic biology. Cell (2011) 1.10
Reduced evolvability of Escherichia coli MDS42, an IS-less cellular chassis for molecular and synthetic biology applications. Microb Cell Fact (2010) 1.10
GenoCAD for iGEM: a grammatical approach to the design of standard-compliant constructs. Nucleic Acids Res (2010) 1.10
Genetic design automation: engineering fantasy or scientific renewal? Trends Biotechnol (2011) 1.08
Prokaryotic gene clusters: a rich toolbox for synthetic biology. Biotechnol J (2010) 1.07
Eugene--a domain specific language for specifying and constraining synthetic biological parts, devices, and systems. PLoS One (2011) 1.06
Automatic design of digital synthetic gene circuits. PLoS Comput Biol (2011) 1.06
Synthetic biology: advancing biological frontiers by building synthetic systems. Genome Biol (2012) 1.06
Applications of genetically-encoded biosensors for the construction and control of biosynthetic pathways. Metab Eng (2011) 1.05
Automatic compilation from high-level biologically-oriented programming language to genetic regulatory networks. PLoS One (2011) 1.05
Strategies for protein synthetic biology. Nucleic Acids Res (2010) 1.04
One-pot DNA construction for synthetic biology: the Modular Overlap-Directed Assembly with Linkers (MODAL) strategy. Nucleic Acids Res (2013) 1.03
Playing God in Frankenstein's Footsteps: Synthetic Biology and the Meaning of Life. Nanoethics (2009) 1.03
Network integration and graph analysis in mammalian molecular systems biology. IET Syst Biol (2008) 1.03
Modeling structure-function relationships in synthetic DNA sequences using attribute grammars. PLoS Comput Biol (2009) 1.03
A synthetic three-color scaffold for monitoring genetic regulation and noise. J Biol Eng (2010) 1.03
Engineering ecosystems and synthetic ecologies. Mol Biosyst (2012) 1.02
Synthetic biology and patents. A European perspective. EMBO Rep (2009) 1.02
Oscillations by minimal bacterial suicide circuits reveal hidden facets of host-circuit physiology. PLoS One (2010) 1.02