Published in Chem Commun (Camb) on October 10, 2005
Minute dosages of alpha(nu)beta3-targeted fumagillin nanoparticles impair Vx-2 tumor angiogenesis and development in rabbits. FASEB J (2008) 1.67
Synthesis, characterization, and biological evaluation of integrin alphavbeta3-targeted PAMAM dendrimers. Mol Pharm (2008) 1.39
A quantitative assessment of nanoparticle-ligand distributions: implications for targeted drug and imaging delivery in dendrimer conjugates. ACS Nano (2010) 1.29
Functional delivery of siRNA in mice using dendriworms. ACS Nano (2009) 1.27
Polymeric nanomedicine for cancer MR imaging and drug delivery. Chem Commun (Camb) (2009) 1.24
Polyfluorophores on a DNA backbone: a multicolor set of labels excited at one wavelength. J Am Chem Soc (2009) 1.19
In vivo optical imaging of integrin alphaV-beta3 in mice using multivalent or monovalent cRGD targeting vectors. Mol Cancer (2007) 1.17
PAMAM-RGD conjugates enhance siRNA delivery through a multicellular spheroid model of malignant glioma. Bioconjug Chem (2009) 1.08
Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis. Arthritis Rheum (2011) 1.03
Quantitative analysis of generation and branch defects in G5 poly(amidoamine) dendrimer. Polymer (Guildf) (2013) 1.00
Integrin Targeted MR Imaging. Theranostics (2011) 1.00
Understanding specific and nonspecific toxicities: a requirement for the development of dendrimer-based pharmaceuticals. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.00
Synthesis and characterization of PAMAM dendrimer-based multifunctional nanodevices for targeting alphavbeta3 integrins. Bioconjug Chem (2007) 0.97
Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery. Bioorg Med Chem Lett (2010) 0.94
Synthesis and characterization of nanoscale dendritic RGD clusters for potential applications in tissue engineering and drug delivery. Int J Nanomedicine (2007) 0.93
Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting. Eur J Med Chem (2011) 0.91
Targeting the efficacy of a dendrimer-based nanotherapeutic in heterogeneous xenograft tumors in vivo. Anticancer Drugs (2010) 0.91
The synthesis of a c(RGDyK) targeted SN38 prodrug with an indolequinone structure for bioreductive drug release. Org Lett (2010) 0.91
The facile synthesis of multifunctional PAMAM dendrimer conjugates through copper-free click chemistry. Bioorg Med Chem Lett (2012) 0.91
RGD dendron bodies; synthetic avidity agents with defined and potentially interchangeable effector sites that can substitute for antibodies. Bioconjug Chem (2009) 0.89
DNA nanotubes as combinatorial vehicles for cellular delivery. Biomacromolecules (2008) 0.88
Binding and transport of PAMAM-RGD in a tumor spheroid model: the effect of RGD targeting ligand density. Biotechnol Bioeng (2011) 0.88
Fluorescence imaging agents in cancerology. Radiol Oncol (2010) 0.87
Avidity modulation of folate-targeted multivalent dendrimers for evaluating biophysical models of cancer targeting nanoparticles. ACS Chem Biol (2013) 0.87
Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform. Bioconjug Chem (2011) 0.86
Dendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry. Mol Pharm (2013) 0.84
Mechanisms and implications of dual-acting methotrexate in folate-targeted nanotherapeutic delivery. Int J Mol Sci (2015) 0.84
A foldamer-dendrimer conjugate neutralizes synaptotoxic β-amyloid oligomers. PLoS One (2012) 0.84
Nanomedicines based on recombinant fusion proteins for targeting therapeutic siRNA oligonucleotides. Ther Deliv (2011) 0.82
Peptide ligands that use a novel binding site to target both TGF-β receptors. Mol Biosyst (2010) 0.82
Peptide- and saccharide-conjugated dendrimers for targeted drug delivery: a concise review. Interface Focus (2012) 0.82
Synthesis and Spectral Studies of CdTe-Dendrimer Conjugates. Nanoscale Res Lett (2009) 0.81
Enhanced optical breakdown in KB cells labeled with folate-targeted silver-dendrimer composite nanodevices. Nanomedicine (2010) 0.80
Targeting and detecting cancer cells using spontaneously formed multifunctional dendrimer-stabilized gold nanoparticles. Analyst (2009) 0.80
Design and in vitro validation of multivalent dendrimer methotrexates as a folate-targeting anticancer therapeutic. Curr Pharm Des (2013) 0.80
Novel peptide-dendrimer conjugates as drug carriers for targeting nonsmall cell lung cancer. Int J Nanomedicine (2010) 0.78
Tumor microvasculature targeting with dendrimer-entrapped gold nanoparticles. Soft Matter (2008) 0.78
In Vivo Biodistribution and Anti-Tumor Efficacy Evaluation of Doxorubicin and Paclitaxel-Loaded Pluronic Micelles Decorated with c(RGDyK) Peptide. PLoS One (2016) 0.78
Biophysical characterization of a riboflavin-conjugated dendrimer platform for targeted drug delivery. Biomacromolecules (2012) 0.78
Atomic force microscopy probing of receptor-nanoparticle interactions for riboflavin receptor targeted gold-dendrimer nanocomposites. J Phys Chem B (2014) 0.76
Dendrimer-doxorubicin conjugates exhibit improved anticancer activity and reduce doxorubicin-induced cardiotoxicity in a murine hepatocellular carcinoma model. PLoS One (2017) 0.75
Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. Cancer Res (2005) 4.71
Artemisinin‐induced dormancy in plasmodium falciparum: duration, recovery rates, and implications in treatment failure. J Infect Dis (2010) 2.89
Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy. J Med Chem (2005) 2.32
Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor. Pharm Res (2002) 2.30
PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality. Biomacromolecules (2006) 2.17
Synthesis and functional evaluation of DNA-assembled polyamidoamine dendrimer clusters for cancer cell-specific targeting. Chem Biol (2005) 2.05
Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum. Antimicrob Agents Chemother (2010) 1.90
Targeting and inhibition of cell growth by an engineered dendritic nanodevice. J Med Chem (2005) 1.80
HER2 specific tumor targeting with dendrimer conjugated anti-HER2 mAb. Bioconjug Chem (2006) 1.36
Transcription and expression of Plasmodium falciparum histidine-rich proteins in different stages and strains: implications for rapid diagnostic tests. PLoS One (2011) 1.35
Dendrimer-epidermal growth factor conjugate displays superagonist activity. Biomacromolecules (2008) 1.31
Targeted gadolinium-loaded dendrimer nanoparticles for tumor-specific magnetic resonance contrast enhancement. Int J Nanomedicine (2008) 1.28
Synthesis and in vitro testing of J591 antibody-dendrimer conjugates for targeted prostate cancer therapy. Bioconjug Chem (2004) 1.24
Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge. Antimicrob Agents Chemother (2011) 1.23
Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers. ACS Nano (2008) 1.22
Synthesis, characterization, and intracellular uptake of carboxyl-terminated poly(amidoamine) dendrimer-stabilized iron oxide nanoparticles. Phys Chem Chem Phys (2007) 1.20
Real-time biomolecular binding detection using a sensitive photonic crystal biosensor. Anal Chem (2010) 1.17
Sensitive molecular binding assay using a photonic crystal structure in total internal reflection. Opt Express (2008) 1.14
In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles. Biomacromolecules (2004) 1.13
Levels of chloroquine resistance in Plasmodium falciparum are determined by loci other than pfcrt and pfmdr1. J Infect Dis (2002) 1.05
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate. Chem Commun (Camb) (2010) 1.04
Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis. Arthritis Rheum (2011) 1.03
Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations. Biomacromolecules (2009) 1.03
Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells. Biomacromolecules (2007) 1.03
In Vivo Monitoring of Multiple Circulating Cell Populations Using Two-photon Flow Cytometry. Opt Commun (2008) 1.02
Activation of human and mouse Kupffer cells by lipopolysaccharide is mediated by CD14. Am J Physiol Gastrointest Liver Physiol (2002) 1.01
Quantitative two-photon flow cytometry--in vitro and in vivo. J Biomed Opt (2008) 1.01
Efficacy, immunogenicity and stability of a novel intranasal nanoemulsion-adjuvanted influenza vaccine in a murine model. Hum Vaccin (2010) 0.98
Preclinical antitumor efficacy evaluation of dendrimer-based methotrexate conjugates. Anticancer Drugs (2008) 0.97
Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery. Bioorg Med Chem Lett (2010) 0.94
HER2 specific delivery of methotrexate by dendrimer conjugated anti-HER2 mAb. Nanotechnology (2008) 0.94
Detection and analysis of tumor fluorescence using a two-photon optical fiber probe. Biophys J (2004) 0.93
Media influences on body satisfaction in female students. Psicothema (2008) 0.93
Fiber-optic multiphoton flow cytometry in whole blood and in vivo. J Biomed Opt (2010) 0.91
Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting. Eur J Med Chem (2011) 0.91
The synthesis of a c(RGDyK) targeted SN38 prodrug with an indolequinone structure for bioreductive drug release. Org Lett (2010) 0.91
Photochemical release of methotrexate from folate receptor-targeting PAMAM dendrimer nanoconjugate. Photochem Photobiol Sci (2012) 0.91
Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia. Am J Clin Nutr (2007) 0.90
Bifunctional PAMAM dendrimer conjugates of folic acid and methotrexate with defined ratio. Biomacromolecules (2012) 0.90
Investigation of tumor cell targeting of a dendrimer nanoparticle using a double-clad optical fiber probe. J Biomed Opt (2008) 0.90
Prevention of influenza pneumonitis by sialic Acid-conjugated dendritic polymers. J Infect Dis (2002) 0.88
Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surface. ACS Nano (2012) 0.87
Avidity modulation of folate-targeted multivalent dendrimers for evaluating biophysical models of cancer targeting nanoparticles. ACS Chem Biol (2013) 0.87
The operations manual: a mechanism for improving the research process. Nurs Res (2002) 0.86
Dendrimer-based tumor cell targeting of fibroblast growth factor-1. Bioorg Med Chem Lett (2009) 0.86
Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform. Bioconjug Chem (2011) 0.86
Nanoemulsion W805EC improves immune responses upon intranasal delivery of an inactivated pandemic H1N1 influenza vaccine. Vaccine (2012) 0.85
Characterization of stability and nasal delivery systems for immunization with nanoemulsion-based vaccines. J Aerosol Med Pulm Drug Deliv (2010) 0.84
Human plasma-mediated hypoxic activation of indolequinone-based naloxone pro-drugs. Bioorg Med Chem Lett (2009) 0.83
Exercise behavior in older adults: a test of the transtheoretical model. J Aging Phys Act (2007) 0.83
Extended cavity laser enhanced two-photon flow cytometry. J Biomed Opt (2008) 0.83
OT-II TCR transgenic mice fail to produce anti-ovalbumin antibodies upon vaccination. Cell Immunol (2013) 0.83
Targeted dendrimeric anticancer prodrug: a methotrexate-folic acid-poly(amidoamine) conjugate and a novel, rapid, "one pot" synthetic approach. Bioconjug Chem (2010) 0.82
Regulation of the human taurine transporter by oxidative stress in retinal pigment epithelial cells stably transformed to overexpress aldose reductase. Antioxid Redox Signal (2005) 0.82
Polyvalent saccharide-functionalized generation 3 poly(amidoamine) dendrimer-methotrexate conjugate as a potential anticancer agent. Bioorg Med Chem (2011) 0.82
Design and in vitro validation of multivalent dendrimer methotrexates as a folate-targeting anticancer therapeutic. Curr Pharm Des (2013) 0.80
PSMA-targeted stably linked "dendrimer-glutamate urea-methotrexate" as a prostate cancer therapeutic. Biomacromolecules (2014) 0.80
Effectiveness of vegetation surrogates for parasitoid wasps in reserve selection. Conserv Biol (2008) 0.79
Sustained analgesia achieved through esterase-activated morphine prodrugs complexed with PAMAM dendrimer. Pharm Res (2012) 0.79
Specific and cooperative interactions between oximes and PAMAM dendrimers as demonstrated by (1)H NMR study. J Phys Chem B (2012) 0.78
Optical fiber-based in vivo quantification of growth factor receptors. Cancer (2011) 0.77
Cancer vaccines. Any future? Arch Immunol Ther Exp (Warsz) (2011) 0.76
Connective tissue activation XXXVIII: heparin/heparanase activity of human platelets resides in a high molecular weight protein, not in connective tissue activating peptide III. J Rheumatol (2002) 0.76
Label-free biosensing using a photonic crystal structure in a total-internal-reflection geometry. Proc SPIE Int Soc Opt Eng (2009) 0.75
Progress in cancer nanotechnology. Prog Mol Biol Transl Sci (2010) 0.75
Folate Receptor-Targeted Dendrimer-Methotrexate Conjugate for Inflammatory Arthritis. J Biomed Nanotechnol (2015) 0.75
Plasma-mediated release of morphine from synthesized prodrugs. Bioorg Med Chem Lett (2010) 0.75