Published in Chem Biol on January 01, 2005
Hydrophobization and bioconjugation for enhanced siRNA delivery and targeting. RNA (2007) 1.46
Navigare necessere est. Improved navigation would help to solve two crucial problems in modern drug therapy: toxicity and precise delivery. EMBO Rep (2005) 1.42
Regulating immune response using polyvalent nucleic acid-gold nanoparticle conjugates. Mol Pharm (2009) 1.40
A quantitative assessment of nanoparticle-ligand distributions: implications for targeted drug and imaging delivery in dendrimer conjugates. ACS Nano (2010) 1.29
Biodistribution studies of protein cage nanoparticles demonstrate broad tissue distribution and rapid clearance in vivo. Int J Nanomedicine (2007) 1.27
In quest of a systematic framework for unifying and defining nanoscience. J Nanopart Res (2009) 1.25
Impact of nanotechnology in cancer: emphasis on nanochemoprevention. Int J Nanomedicine (2012) 1.05
Flow chamber analysis of size effects in the adhesion of spherical particles. Int J Nanomedicine (2007) 0.99
Dendrimer-triglycine-EGF nanoparticles for tumor imaging and targeted nucleic acid and drug delivery. Oral Oncol (2010) 0.98
Molecular dynamics studies of the size, shape, and internal structure of 0% and 90% acetylated fifth-generation polyamidoamine dendrimers in water and methanol. J Phys Chem B (2006) 0.97
Nanotechnology-based approaches in anticancer research. Int J Nanomedicine (2012) 0.93
Multiscale modeling of dendrimers and their interactions with bilayers and polyelectrolytes. Molecules (2009) 0.92
Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting. Eur J Med Chem (2011) 0.91
RGD dendron bodies; synthetic avidity agents with defined and potentially interchangeable effector sites that can substitute for antibodies. Bioconjug Chem (2009) 0.89
Design, synthesis, and biological functionality of a dendrimer-based modular drug delivery platform. Bioconjug Chem (2011) 0.86
RNA interference and antiviral therapy. World J Gastroenterol (2007) 0.86
Combinatorial and rational approaches to polymer synthesis for medicine. Adv Drug Deliv Rev (2008) 0.86
Cellular uptake mechanism and intracellular fate of hydrophobically modified pullulan nanoparticles. Int J Nanomedicine (2013) 0.85
A multivalent probe for AI-2 quorum-sensing receptors. J Am Chem Soc (2011) 0.81
Targeting cancer cells with dendrimers. Chem Biol (2005) 0.81
Wireless fluorescence capsule for endoscopy using single photon-based detection. Sci Rep (2015) 0.80
Nanoparticles as Drug Delivery Systems in Cancer Medicine: Emphasis on RNAi-Containing Nanoliposomes. Pharmaceuticals (Basel) (2013) 0.78
Polymeric micelle-based bioassay with femtomolar sensitivity. Anal Biochem (2007) 0.78
Biophysical characterization of a riboflavin-conjugated dendrimer platform for targeted drug delivery. Biomacromolecules (2012) 0.78
DNA-melamine hybrid molecules: from self-assembly to nanostructures. Beilstein J Nanotechnol (2015) 0.77
Nanotechnology of emerging targeting systems. Minerva Biotecnol (2008) 0.75
The baffling human body and the boundless nanomaterial boon-a trap for cancer crab. J Clin Diagn Res (2014) 0.75
Tumor cell imaging using the intrinsic emission from PAMAM dendrimer: a case study with HeLa cells. Cytotechnology (2009) 0.75
Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer. Cancer Res (2005) 4.71
The binding avidity of a nanoparticle-based multivalent targeted drug delivery platform. Chem Biol (2007) 3.36
Interaction of polycationic polymers with supported lipid bilayers and cells: nanoscale hole formation and enhanced membrane permeability. Bioconjug Chem (2006) 2.87
Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport. Bioconjug Chem (2004) 2.66
Nanoparticle interaction with biological membranes: does nanotechnology present a Janus face? Acc Chem Res (2007) 2.34
Poly(amidoamine) dendrimer-based multifunctional engineered nanodevice for cancer therapy. J Med Chem (2005) 2.32
Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor. Pharm Res (2002) 2.30
PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality. Biomacromolecules (2006) 2.17
Targeted drug delivery with dendrimers: comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex. Adv Drug Deliv Rev (2005) 1.97
Wide varieties of cationic nanoparticles induce defects in supported lipid bilayers. Nano Lett (2008) 1.96
Protein modification, bioconjugation, and disulfide bridging using bromomaleimides. J Am Chem Soc (2010) 1.89
Targeting and inhibition of cell growth by an engineered dendritic nanodevice. J Med Chem (2005) 1.80
Dendritic polymer macromolecular carriers for drug delivery. Curr Opin Chem Biol (2002) 1.77
Applications of nanotechnology for immunology. Nat Rev Immunol (2013) 1.65
Tumor angiogenic vasculature targeting with PAMAM dendrimer-RGD conjugates. Chem Commun (Camb) (2005) 1.58
Lipid bilayer disruption by polycationic polymers: the roles of size and chemical functional group. Langmuir (2005) 1.56
Dendrimer-entrapped gold nanoparticles as a platform for cancer-cell targeting and imaging. Small (2007) 1.45
Direct observation of lipid bilayer disruption by poly(amidoamine) dendrimers. Chem Phys Lipids (2004) 1.42
Bromomaleimides: new reagents for the selective and reversible modification of cysteine. Chem Commun (Camb) (2009) 1.40
Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis. Chem Commun (Camb) (2011) 1.38
Pre-event smallpox vaccination and postevent exposure and disease: a report of the Joint Task Force on Smallpox Vaccination for Allergists. Ann Allergy Asthma Immunol (2005) 1.38
HER2 specific tumor targeting with dendrimer conjugated anti-HER2 mAb. Bioconjug Chem (2006) 1.36
In situ maleimide bridging of disulfides and a new approach to protein PEGylation. Bioconjug Chem (2011) 1.33
Dendrimer-epidermal growth factor conjugate displays superagonist activity. Biomacromolecules (2008) 1.31
A quantitative assessment of nanoparticle-ligand distributions: implications for targeted drug and imaging delivery in dendrimer conjugates. ACS Nano (2010) 1.29
Targeted gadolinium-loaded dendrimer nanoparticles for tumor-specific magnetic resonance contrast enhancement. Int J Nanomedicine (2008) 1.28
Mucosal immunization with a novel nanoemulsion-based recombinant anthrax protective antigen vaccine protects against Bacillus anthracis spore challenge. Infect Immun (2007) 1.27
Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes. J Phys Chem B (2009) 1.27
Synthesis and in vitro testing of J591 antibody-dendrimer conjugates for targeted prostate cancer therapy. Bioconjug Chem (2004) 1.24
Synthesis, characterization, and in vitro testing of superparamagnetic iron oxide nanoparticles targeted using folic Acid-conjugated dendrimers. ACS Nano (2008) 1.22
The role of apoptosis in thyroid autoimmunity. Thyroid (2007) 1.20
Synthesis, characterization, and intracellular uptake of carboxyl-terminated poly(amidoamine) dendrimer-stabilized iron oxide nanoparticles. Phys Chem Chem Phys (2007) 1.20
Pre-clinical evaluation of a novel nanoemulsion-based hepatitis B mucosal vaccine. PLoS One (2008) 1.20
Nasal immunization with a recombinant HIV gp120 and nanoemulsion adjuvant produces Th1 polarized responses and neutralizing antibodies to primary HIV type 1 isolates. AIDS Res Hum Retroviruses (2008) 1.18
Development of immune response that protects mice from viral pneumonitis after a single intranasal immunization with influenza A virus and nanoemulsion. Vaccine (2003) 1.17
Real-time biomolecular binding detection using a sensitive photonic crystal biosensor. Anal Chem (2010) 1.17
Bromopyridazinedione-mediated protein and peptide bioconjugation. Chem Commun (Camb) (2011) 1.15
Current dendrimer applications in cancer diagnosis and therapy. Curr Top Med Chem (2008) 1.14
Sensitive molecular binding assay using a photonic crystal structure in total internal reflection. Opt Express (2008) 1.14
Silver/dendrimer nanocomposites as biomarkers: fabrication, characterization, in vitro toxicity, and intracellular detection. Nano Lett (2005) 1.13
In vitro targeting of synthesized antibody-conjugated dendrimer nanoparticles. Biomacromolecules (2004) 1.13
Two-photon fluorescence correlation spectroscopy through a dual-clad optical fiber. Opt Express (2008) 1.12
Isolation and characterization of dendrimers with precise numbers of functional groups. Chemistry (2010) 1.11
Bromomaleimide-linked bioconjugates are cleavable in mammalian cells. Chembiochem (2011) 1.09
Induction of Th17 cellular immunity with a novel nanoemulsion adjuvant. Crit Rev Immunol (2010) 1.07
HPLC analysis of PAMAM dendrimer based multifunctional devices. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.07
Synthetic PAMAM-RGD conjugates target and bind to odontoblast-like MDPC 23 cells and the predentin in tooth organ cultures. Bioconjug Chem (2007) 1.06
The role of ganglioside GM1 in cellular internalization mechanisms of poly(amidoamine) dendrimers. Bioconjug Chem (2009) 1.05
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugate. Chem Commun (Camb) (2010) 1.04
A novel, killed-virus nasal vaccinia virus vaccine. Clin Vaccine Immunol (2007) 1.03
Folate-targeted nanoparticles show efficacy in the treatment of inflammatory arthritis. Arthritis Rheum (2011) 1.03
Dendrimer-based targeted delivery of an apoptotic sensor in cancer cells. Biomacromolecules (2007) 1.03
Cationic poly(amidoamine) dendrimer induces lysosomal apoptotic pathway at therapeutically relevant concentrations. Biomacromolecules (2009) 1.03
Poly(amidoamine) dendrimers on lipid bilayers I: Free energy and conformation of binding. J Phys Chem B (2008) 1.02
In Vivo Monitoring of Multiple Circulating Cell Populations Using Two-photon Flow Cytometry. Opt Commun (2008) 1.02
A novel inactivated intranasal respiratory syncytial virus vaccine promotes viral clearance without Th2 associated vaccine-enhanced disease. PLoS One (2011) 1.02
Quantitative two-photon flow cytometry--in vitro and in vivo. J Biomed Opt (2008) 1.01
Quantitative analysis of generation and branch defects in G5 poly(amidoamine) dendrimer. Polymer (Guildf) (2013) 1.00
The implications of stochastic synthesis for the conjugation of functional groups to nanoparticles. Bioconjug Chem (2008) 1.00
Understanding specific and nonspecific toxicities: a requirement for the development of dendrimer-based pharmaceuticals. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 1.00
Homogeneous antibody fragment conjugation by disulfide bridging introduces 'spinostics'. Sci Rep (2013) 0.99
Efficacy, immunogenicity and stability of a novel intranasal nanoemulsion-adjuvanted influenza vaccine in a murine model. Hum Vaccin (2010) 0.98
Polymeric dibromomaleimides as extremely efficient disulfide bridging bioconjugation and pegylation agents. J Am Chem Soc (2012) 0.98
Best practices for purification and characterization of PAMAM dendrimer. Macromolecules (2012) 0.98
The fungicidal activity of novel nanoemulsion (X8W60PC) against clinically important yeast and filamentous fungi. Mycopathologia (2002) 0.98
Biosensing based on two-photon fluorescence measurements through optical fibers. Opt Lett (2002) 0.98
Multifunctional dendrimer-modified multiwalled carbon nanotubes: synthesis, characterization, and in vitro cancer cell targeting and imaging. Biomacromolecules (2009) 0.97
Molecular dynamics studies of the size, shape, and internal structure of 0% and 90% acetylated fifth-generation polyamidoamine dendrimers in water and methanol. J Phys Chem B (2006) 0.97
Preclinical antitumor efficacy evaluation of dendrimer-based methotrexate conjugates. Anticancer Drugs (2008) 0.97
HPLC separation of different generations of poly(amidoamine) dendrimers modified with various terminal groups. Anal Chem (2005) 0.96
A unique combination of inflammatory cytokines enhances apoptosis of thyroid follicular cells and transforms nondestructive to destructive thyroiditis in experimental autoimmune thyroiditis. J Immunol (2002) 0.96
IFNgamma sensitization to TRAIL-induced apoptosis in human thyroid carcinoma cells by upregulating Bak expression. Oncogene (2004) 0.95
Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted delivery. Bioorg Med Chem Lett (2010) 0.94
Nanoemulsion mucosal adjuvant uniquely activates cytokine production by nasal ciliated epithelium and induces dendritic cell trafficking. Eur J Immunol (2012) 0.94
HER2 specific delivery of methotrexate by dendrimer conjugated anti-HER2 mAb. Nanotechnology (2008) 0.94
Synthesis, characterization and stability of a luteinizing hormone-releasing hormone (LHRH)-functionalized poly(amidoamine) dendrimer conjugate. J Biomater Sci Polym Ed (2008) 0.94
Detection and analysis of tumor fluorescence using a two-photon optical fiber probe. Biophys J (2004) 0.93
Copper-free click conjugation of methotrexate to a PAMAM dendrimer platform. Tetrahedron Lett (2011) 0.93
Development of a remanence measurement-based SQUID system with in-depth resolution for nanoparticle imaging. Phys Med Biol (2009) 0.93
Methotrexate delivery via folate targeted dendrimer-based nanotherapeutic platform. Wiley Interdiscip Rev Nanomed Nanobiotechnol (2010) 0.93