Published in Mol Microbiol on December 01, 2005
Molecular regulation of antibiotic biosynthesis in streptomyces. Microbiol Mol Biol Rev (2013) 2.24
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The twin-arginine translocation pathway is a major route of protein export in Streptomyces coelicolor. Proc Natl Acad Sci U S A (2006) 1.34
Interspecies DNA microarray analysis identifies WblA as a pleiotropic down-regulator of antibiotic biosynthesis in Streptomyces. J Bacteriol (2007) 1.15
Triggers and cues that activate antibiotic production by actinomycetes. J Ind Microbiol Biotechnol (2013) 1.14
"Pseudo" gamma-butyrolactone receptors respond to antibiotic signals to coordinate antibiotic biosynthesis. J Biol Chem (2010) 1.14
Phosphorylated AbsA2 negatively regulates antibiotic production in Streptomyces coelicolor through interactions with pathway-specific regulatory gene promoters. J Bacteriol (2007) 1.12
Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2). BMC Genomics (2008) 1.12
Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074. Microb Biotechnol (2014) 1.03
Regulation of morphological differentiation in S. coelicolor by RNase III (AbsB) cleavage of mRNA encoding the AdpA transcription factor. Mol Microbiol (2010) 1.01
Mass spectrometric screening of transcriptional regulators involved in antibiotic biosynthesis in Streptomyces coelicolor A3(2). J Ind Microbiol Biotechnol (2009) 1.01
Regulation of ppk expression and in vivo function of Ppk in Streptomyces lividans TK24. J Bacteriol (2006) 1.01
Genetic factors that influence moenomycin production in streptomycetes. J Ind Microbiol Biotechnol (2010) 1.00
Transcriptome dynamics-based operon prediction and verification in Streptomyces coelicolor. Nucleic Acids Res (2007) 1.00
The gene encoding RNase III in Streptomyces coelicolor is transcribed during exponential phase and is required for antibiotic production and for proper sporulation. J Bacteriol (2008) 0.97
RNA-Seq and RNA immunoprecipitation analyses of the transcriptome of Streptomyces coelicolor identify substrates for RNase III. J Bacteriol (2012) 0.94
Identification of a gene negatively affecting antibiotic production and morphological differentiation in Streptomyces coelicolor A3(2). J Bacteriol (2006) 0.94
Characterization of rrdA, a TetR family protein gene involved in the regulation of secondary metabolism in Streptomyces coelicolor. Appl Environ Microbiol (2009) 0.94
Hopanoids are not essential for growth of Streptomyces scabies 87-22. J Bacteriol (2009) 0.93
In vivo studies suggest that induction of VanS-dependent vancomycin resistance requires binding of the drug to D-Ala-D-Ala termini in the peptidoglycan cell wall. Antimicrob Agents Chemother (2013) 0.93
Two-component systems in Streptomyces: key regulators of antibiotic complex pathways. Microb Cell Fact (2013) 0.93
The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase. Nucleic Acids Res (2013) 0.91
Autoregulation of AbsB (RNase III) expression in Streptomyces coelicolor by endoribonucleolytic cleavage of absB operon transcripts. J Bacteriol (2008) 0.91
Expression of the Streptomyces coelicolor SoxR regulon is intimately linked with actinorhodin production. J Bacteriol (2010) 0.89
Genome-wide inference of regulatory networks in Streptomyces coelicolor. BMC Genomics (2010) 0.88
Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin. Open Biol (2013) 0.87
Regulation of a novel gene cluster involved in secondary metabolite production in Streptomyces coelicolor. J Bacteriol (2010) 0.87
Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor. J Bacteriol (2008) 0.86
Synthetic promoter library for modulation of actinorhodin production in Streptomyces coelicolor A3(2). PLoS One (2014) 0.85
An orphan histidine kinase, OhkA, regulates both secondary metabolism and morphological differentiation in Streptomyces coelicolor. J Bacteriol (2011) 0.85
Complex transcriptional control of the antibiotic regulator afsS in Streptomyces: PhoP and AfsR are overlapping, competitive activators. J Bacteriol (2011) 0.84
The phage growth limitation system in Streptomyces coelicolor A(3)2 is a toxin/antitoxin system, comprising enzymes with DNA methyltransferase, protein kinase and ATPase activity. Virology (2015) 0.83
Disruption of the siderophore-binding desE receptor gene in Streptomyces coelicolor A3(2) results in impaired growth in spite of multiple iron-siderophore transport systems. Microb Biotechnol (2011) 0.82
Deciphering the regulon of Streptomyces coelicolor AbrC3, a positive response regulator of antibiotic production. Appl Environ Microbiol (2014) 0.82
Bacterial transmembrane proteins that lack N-terminal signal sequences. PLoS One (2011) 0.80
BldG and SCO3548 interact antagonistically to control key developmental processes in Streptomyces coelicolor. J Bacteriol (2009) 0.80
Identification and characterization of NocR as a positive transcriptional regulator of the beta-lactam nocardicin A in Nocardia uniformis. J Bacteriol (2008) 0.79
Complex intra-operonic dynamics mediated by a small RNA in Streptomyces coelicolor. PLoS One (2014) 0.79
Constitutive overexpression of asm2 and asm39 increases AP-3 production in the actinomycete Actinosynnema pretiosum. J Ind Microbiol Biotechnol (2009) 0.77
Dynamic localization of Tat protein transport machinery components in Streptomyces coelicolor. J Bacteriol (2012) 0.77
The adnAB locus, encoding a putative helicase-nuclease activity, is essential in Streptomyces. J Bacteriol (2014) 0.77
Determination of phosphorylation sites in the DivIVA cytoskeletal protein of Streptomyces coelicolor by targeted LC-MS/MS. J Proteome Res (2013) 0.76
Development, antibiotic production, and ribosome assembly in Streptomyces venezuelae are impacted by RNase J and RNase III deletion. J Bacteriol (2014) 0.76
Duplication and evolution of devA-like genes in Streptomyces has resulted in distinct developmental roles. PLoS One (2011) 0.76
Properties of lanK-based regulatory circuit involved in landomycin biosynthesis in Streptomyces cyanogenus S136. Genetika (2010) 0.76
Tools for metabolic engineering in Streptomyces. Bioengineered (2014) 0.75
A Cassette Containing Thiostrepton, Gentamicin Resistance Genes, and dif sequences Is Effective in Construction of Recombinant Mycobacteria. Front Microbiol (2017) 0.75
Recent advances in understanding Streptomyces. F1000Res (2016) 0.75
Regulatory genes and their roles for improvement of antibiotic biosynthesis in Streptomyces. 3 Biotech (2017) 0.75
Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med (2010) 17.57
Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays. Proc Natl Acad Sci U S A (2002) 6.93
Structural and functional features and significance of the physical linkage between ER and mitochondria. J Cell Biol (2006) 5.37
SOS response induction by beta-lactams and bacterial defense against antibiotic lethality. Science (2004) 4.20
Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury. Crit Care (2013) 3.90
Giant magnetoresistance in organic spin-valves. Nature (2004) 3.72
Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium. Nat Rev Microbiol (2009) 3.28
Control of mitochondrial motility and distribution by the calcium signal: a homeostatic circuit. J Cell Biol (2004) 3.12
Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication. Am J Respir Crit Care Med (2014) 2.93
Application of combinatorial chemistry science on modern drug discovery. J Comb Chem (2008) 2.64
TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation. Proc Natl Acad Sci U S A (2003) 2.46
The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin. Cell (2006) 2.40
Effects of threshold choice on biological conclusions reached during analysis of gene expression by DNA microarrays. Proc Natl Acad Sci U S A (2005) 2.37
Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma. J Allergy Clin Immunol (2004) 2.33
Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci. Proc Natl Acad Sci U S A (2003) 2.18
MICU1 controls both the threshold and cooperative activation of the mitochondrial Ca²⁺ uniporter. Cell Metab (2013) 2.15
Thiol-based regulatory switches. Annu Rev Genet (2003) 2.14
Mitochondrial 'kiss-and-run': interplay between mitochondrial motility and fusion-fission dynamics. EMBO J (2009) 2.11
The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor. Proc Natl Acad Sci U S A (2004) 2.04
Global analysis of Escherichia coli RNA degradosome function using DNA microarrays. Proc Natl Acad Sci U S A (2004) 1.94
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission. Nat Chem Biol (2007) 1.83
Convergence of conduction bands as a means of enhancing thermoelectric performance of n-type Mg2Si(1-x)Sn(x) solid solutions. Phys Rev Lett (2012) 1.81
The chaplins: a family of hydrophobic cell-surface proteins involved in aerial mycelium formation in Streptomyces coelicolor. Genes Dev (2003) 1.80
DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization. Mol Cell (2010) 1.78
Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein. Proc Natl Acad Sci U S A (2012) 1.72
Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue. Blood (2014) 1.71
RNase G complementation of rne null mutation identifies functional interrelationships with RNase E in Escherichia coli. Mol Microbiol (2002) 1.66
Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism. Structure (2009) 1.64
Recruitment of terminal protein to the ends of Streptomyces linear plasmids and chromosomes by a novel telomere-binding protein essential for linear DNA replication. Genes Dev (2003) 1.58
Dementia lacking distinctive histology (DLDH) revisited. Acta Neuropathol (2006) 1.58
A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor. Nat Chem Biol (2010) 1.51
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance. Mol Microbiol (2004) 1.50
The Mycobacterium tuberculosis FAS-II condensing enzymes: their role in mycolic acid biosynthesis, acid-fastness, pathogenesis and in future drug development. Mol Microbiol (2007) 1.49
Empowering young scientists. Science (2010) 1.47
The Role of zinc in the disulphide stress-regulated anti-sigma factor RsrA from Streptomyces coelicolor. J Mol Biol (2003) 1.42
Evidence that the Streptomyces developmental protein WhiD, a member of the WhiB family, binds a [4Fe-4S] cluster. J Biol Chem (2004) 1.42
The role of the novel Fem protein VanK in vancomycin resistance in Streptomyces coelicolor. J Biol Chem (2005) 1.42
Bidirectional effect of Wnt signaling antagonist DKK1 on the modulation of anthrax toxin uptake. Sci China Life Sci (2014) 1.41
Protein-passivated Fe(3)O(4) nanoparticles: low toxicity and rapid heating for thermal therapy. J Mater Chem (2008) 1.39
An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma. Oncogene (2005) 1.38
Metamaterial with simultaneously negative bulk modulus and mass density. Phys Rev Lett (2007) 1.38
Complete genome analysis of the C4 subgenotype strains of enterovirus 71: predominant recombination C4 viruses persistently circulating in China for 14 years. PLoS One (2013) 1.36
Genome plasticity in Streptomyces: identification of 1 Mb TIRs in the S. coelicolor A3(2) chromosome. Mol Microbiol (2004) 1.35
RraA. a protein inhibitor of RNase E activity that globally modulates RNA abundance in E. coli. Cell (2003) 1.34
The vancomycin resistance VanRS two-component signal transduction system of Streptomyces coelicolor. Mol Microbiol (2006) 1.34
Rates of sexual victimization in prison for inmates with and without mental disorders. Psychiatr Serv (2007) 1.32
A Streptomyces coelicolor functional orthologue of Escherichia coli RNase E shows shuffling of catalytic and PNPase-binding domains. Mol Microbiol (2003) 1.31
A rare leucine codon in adpA is implicated in the morphological defect of bldA mutants of Streptomyces coelicolor. Mol Microbiol (2003) 1.31
Redox control in actinobacteria. Biochim Biophys Acta (2008) 1.30
A master regulator sigmaB governs osmotic and oxidative response as well as differentiation via a network of sigma factors in Streptomyces coelicolor. Mol Microbiol (2005) 1.28
Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth. Mol Microbiol (2010) 1.26
Differential modulation of E. coli mRNA abundance by inhibitory proteins that alter the composition of the degradosome. Mol Microbiol (2006) 1.26
Vancomycin resistance VanS/VanR two-component systems. Adv Exp Med Biol (2008) 1.25
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathol (2006) 1.24
Lift-off PMN-PT Thick Film for High Frequency Ultrasonic Biomicroscopy. J Am Ceram Soc (2010) 1.24
Smurf2 up-regulation activates telomere-dependent senescence. Genes Dev (2004) 1.23
A crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyrase. Science (2009) 1.23
Inhibition of HIV budding by a genetically selected cyclic peptide targeting the Gag-TSG101 interaction. ACS Chem Biol (2008) 1.23
Specialized osmotic stress response systems involve multiple SigB-like sigma factors in Streptomyces coelicolor. Mol Microbiol (2003) 1.21
Anisotropic thermopower and planar Nernst effect in Ga1-xMnxAs ferromagnetic semiconductors. Phys Rev Lett (2006) 1.19
Identification and structure of the anti-sigma factor-binding domain of the disulphide-stress regulated sigma factor sigma(R) from Streptomyces coelicolor. J Mol Biol (2002) 1.19
Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2). Microbiology (2004) 1.18
The Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residue. J Biol Chem (2008) 1.18
Evolutionary relationships among actinophages and a putative adaptation for growth in Streptomyces spp. J Bacteriol (2013) 1.17
Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the 'AMC-Senshu' method. Ann Rheum Dis (2012) 1.16
A signal transduction system in Streptomyces coelicolor that activates the expression of a putative cell wall glycan operon in response to vancomycin and other cell wall-specific antibiotics. Mol Microbiol (2002) 1.16
Mechanistic insight into the nitrosylation of the [4Fe-4S] cluster of WhiB-like proteins. J Am Chem Soc (2010) 1.16
Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis. J Biol Chem (2010) 1.15
From the characterization of the four serine/threonine protein kinases (PknA/B/G/L) of Corynebacterium glutamicum toward the role of PknA and PknB in cell division. J Biol Chem (2008) 1.15
Interspecies DNA microarray analysis identifies WblA as a pleiotropic down-regulator of antibiotic biosynthesis in Streptomyces. J Bacteriol (2007) 1.15
Tapetum degeneration retardation is critical for aliphatic metabolism and gene regulation during rice pollen development. Mol Plant (2008) 1.15
A key developmental regulator controls the synthesis of the antibiotic erythromycin in Saccharopolyspora erythraea. Proc Natl Acad Sci U S A (2008) 1.15
Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays. Metab Eng (2004) 1.14
The Ser/Thr protein kinase AfsK regulates polar growth and hyphal branching in the filamentous bacteria Streptomyces. Proc Natl Acad Sci U S A (2012) 1.14
Pharmacokinetics of levetiracetam in neonates with seizures. J Pediatr (2011) 1.13
Heterodimeric integrin complexes containing beta1-integrin promote internalization and lethality of anthrax toxin. Proc Natl Acad Sci U S A (2010) 1.11
OsPHF1 regulates the plasma membrane localization of low- and high-affinity inorganic phosphate transporters and determines inorganic phosphate uptake and translocation in rice. Plant Physiol (2011) 1.11
The Streptomyces coelicolor polynucleotide phosphorylase homologue, and not the putative poly(A) polymerase, can polyadenylate RNA. J Bacteriol (2003) 1.10
Analysis of DNA microarrays using algorithms that employ rule-based expert knowledge. Proc Natl Acad Sci U S A (2002) 1.10
Prognostic significance of aberrant gene methylation in gastric cancer. Am J Cancer Res (2011) 1.10
Associations among lipids, leptin, and leptin receptor gene Gin223Arg polymorphisms and breast cancer in China. Biol Trace Elem Res (2008) 1.08
Panoramic radiographic atheromas portend adverse vascular events. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2007) 1.08
Regulation of apical growth and hyphal branching in Streptomyces. Curr Opin Microbiol (2012) 1.08
Suppression of human tumor cell proliferation by Smurf2-induced senescence. J Cell Physiol (2008) 1.07
EST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxin. Proc Natl Acad Sci U S A (2004) 1.07
SapB and the chaplins: connections between morphogenetic proteins in Streptomyces coelicolor. Mol Microbiol (2007) 1.06